Heparanase levels are elevated in the urine and plasma of type 2 diabetes patients and associate with blood glucose levels
Shafat, Itay, Ilan, Neta, Zoabi, Samih, Vlodavsky, Israel, Nakhoul, Farid
Published in PloS one (22.02.2011)
Published in PloS one (22.02.2011)
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Journal Article
The heparanase system and tumor metastasis: is heparanase the seed and soil?
Arvatz, Gil, Shafat, Itay, Levy-Adam, Flonia, Ilan, Neta, Vlodavsky, Israel
Published in Cancer and metastasis reviews (01.06.2011)
Published in Cancer and metastasis reviews (01.06.2011)
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Journal Article
Characterization of Mechanisms Involved in Secretion of Active Heparanase
Shafat, Itay, Vlodavsky, Israel, Ilan, Neta
Published in The Journal of biological chemistry (18.08.2006)
Published in The Journal of biological chemistry (18.08.2006)
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Journal Article
Elevated urine heparanase levels are associated with proteinuria and decreased renal allograft function
Shafat, Itay, Agbaria, Amir, Boaz, Mona, Schwartz, Doron, Baruch, Ronny, Nakash, Richard, Ilan, Neta, Vlodavsky, Israel, Weinstein, Talia
Published in PloS one (13.09.2012)
Published in PloS one (13.09.2012)
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Journal Article
Alternatively Spliced Spalax Heparanase Inhibits Extracellular Matrix Degradation, Tumor Growth, and Metastasis
Nasser, Nicola J., Avivi, Aaron, Shafat, Itay, Edovitsky, Evgeny, Zcharia, Eyal, Ilan, Neta, Vlodavsky, Israel, Nevo, Eviatar
Published in Proceedings of the National Academy of Sciences - PNAS (17.02.2009)
Published in Proceedings of the National Academy of Sciences - PNAS (17.02.2009)
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Journal Article
Heparanase: One Molecule with Multiple Functions in Cancer Progression
Vlodavsky, Israel, Elkin, Michael, Abboud-Jarrous, Ghada, Levi-Adam, Flonia, Fuks, Liat, Shafat, Itay, Ilan, Neta
Published in Connective Tissue Research (01.01.2008)
Published in Connective Tissue Research (01.01.2008)
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Journal Article
Clinical Significance of Urine Heparanase in Bladder Cancer Progression
Shafat, Itay, Pode, Dov, Peretz, Tamar, Ilan, Neta, Vlodavsky, Israel, Benjamin, Nisman
Published in Neoplasia (New York, N.Y.) (01.02.2008)
Published in Neoplasia (New York, N.Y.) (01.02.2008)
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Journal Article
Heparanase regulates retention and proliferation of primitive Sca-1+/c-Kit+/Lin− cells via modulation of the bone marrow microenvironment
Spiegel, Asaf, Zcharia, Eyal, Vagima, Yaron, Itkin, Tomer, Kalinkovich, Alexander, Dar, Ayelet, Kollet, Orit, Netzer, Neta, Golan, Karin, Shafat, Itay, Ilan, Neta, Nagler, Arnon, Vlodavsky, Israel, Lapidot, Tsvee
Published in Blood (15.05.2008)
Published in Blood (15.05.2008)
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Journal Article
Inverse correlation between HPSE gene single nucleotide polymorphisms and heparanase expression: possibility of multiple levels of heparanase regulation
Ostrovsky, Olga, Korostishevsky, Michael, Shafat, Itay, Mayorov, Margarita, Ilan, Neta, Vlodavsky, Israel, Nagler, Arnon
Published in Journal of leukocyte biology (01.08.2009)
Published in Journal of leukocyte biology (01.08.2009)
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Journal Article
Heparanase Levels Are Elevated in the Plasma of Pediatric Cancer Patients and Correlate with Response to Anticancer Treatment
Shafat, Itay, Barak, Ayelet Ben, Postovsky, Sergey, Elhasid, Ronit, Ilan, Neta, Vlodavsky, Israel, Ben Arush, Miriam Weyl
Published in Neoplasia (New York, N.Y.) (01.11.2007)
Published in Neoplasia (New York, N.Y.) (01.11.2007)
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Journal Article
Low and high affinity receptors mediate cellular uptake of heparanase
Ben-Zaken, Olga, Shafat, Itay, Gingis-Velitski, Svetlana, Bangio, Haim, Kelson, Idil Kasuto, Alergand, Tal, Amor, Yehudit, Maya, Ruth Ben-Yakar, Vlodavsky, Israel, Ilan, Neta
Published in The international journal of biochemistry & cell biology (01.01.2008)
Published in The international journal of biochemistry & cell biology (01.01.2008)
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Journal Article
Adaptive Evolution of Heparanase in Hypoxia-Tolerant Spalax: Gene Cloning and Identification of a Unique Splice Variant
Nicola J. Nasser, Nevo, Eviatar, Itay Shafat, Neta Ilant, Vlodavsky, Israel, Avivi, Aaron
Published in Proceedings of the National Academy of Sciences - PNAS (18.10.2005)
Published in Proceedings of the National Academy of Sciences - PNAS (18.10.2005)
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Journal Article
Macrophage Activation by Heparanase Is Mediated by TLR-2 and TLR-4 and Associates With Plaque Progression
Blich, Miry, Golan, Amnon, Arvatz, Gil, Sebbag, Anat, Shafat, Itay, Sabo, Edmond, Cohen-Kaplan, Victoria, Petcherski, Sirouch, Avniel-Polak, Shani, Eitan, Amnon, Hammerman, Haim, Aronson, Doron, Axelman, Elena, Ilan, Neta, Nussbaum, Gabriel, Vlodavsky, Israel
Published in Arteriosclerosis, thrombosis, and vascular biology (01.02.2013)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.02.2013)
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Journal Article
An assay to evaluate heparanase procoagulant activity
Nadir, Yona, Kenig, Yael, Drugan, Arie, Shafat, Itay, Brenner, Benjamin
Published in Thrombosis research (01.10.2011)
Published in Thrombosis research (01.10.2011)
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Journal Article
Pre‐clinical and clinical significance of heparanase in Ewing’s sarcoma
Shafat, Itay, Ben‐Arush, Myriam Weyl, Issakov, Josephine, Meller, Isaac, Naroditsky, Inna, Tortoreto, Monica, Cassinelli, Giuliana, Lanzi, Cinzia, Pisano, Claudio, Ilan, Neta, Vlodavsky, Israel, Zunino, Franco
Published in Journal of cellular and molecular medicine (01.09.2011)
Published in Journal of cellular and molecular medicine (01.09.2011)
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Journal Article
Selective Autoantibody Production against CCL3 Is Associated with Human Type 1 Diabetes Mellitus and Serves As a Novel Biomarker for Its Diagnosis
Shehadeh, Naim, Pollack, Shirly, Wildbaum, Gizi, Zohar, Yaniv, Shafat, Itay, Makhoul, Reem, Daod, Essam, Hakim, Fahed, Perlman, Rina, Karin, Nathan
Published in The Journal of immunology (1950) (15.06.2009)
Published in The Journal of immunology (1950) (15.06.2009)
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Journal Article
Macrophages activation by heparanase is mediated by TLR-2 and TLR-4 and associates with plaque progression
Blich, Miry, Golan, Amnon, Arvatz, Gil, Sebbag, Anat, Shafat, Itay, Sabo, Edmond, Cohen-Kaplan, Victoria, Petcherski, Sirouch, Avniel-Polak, Shani, Eitan, Amnon, Hammerman, Haim, Aronson, Doron, Axelman, Elena, Ilan, Neta, Nussbaum, Gabriel, Vlodavsky, Israel
Published in Arteriosclerosis, thrombosis, and vascular biology (15.11.2012)
Published in Arteriosclerosis, thrombosis, and vascular biology (15.11.2012)
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Journal Article