αβ T cell receptors as predictors of health and disease
Attaf, Meriem, Huseby, Eric, Sewell, Andrew K
Published in Cellular & molecular immunology (01.07.2015)
Published in Cellular & molecular immunology (01.07.2015)
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The promise of γδ T cells and the γδ T cell receptor for cancer immunotherapy
Legut, Mateusz, Cole, David K, Sewell, Andrew K
Published in Cellular & molecular immunology (01.11.2015)
Published in Cellular & molecular immunology (01.11.2015)
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Coreceptor Scanning by the T Cell Receptor Provides a Mechanism for T Cell Tolerance
Stepanek, Ondrej, Prabhakar, Arvind S., Osswald, Celine, King, Carolyn G., Bulek, Anna, Naeher, Dieter, Beaufils-Hugot, Marina, Abanto, Michael L., Galati, Virginie, Hausmann, Barbara, Lang, Rosemarie, Cole, David K., Huseby, Eric S., Sewell, Andrew K., Chakraborty, Arup K., Palmer, Ed
Published in Cell (09.10.2014)
Published in Cell (09.10.2014)
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Human TRAV1-2-negative MR1-restricted T cells detect S. pyogenes and alternatives to MAIT riboflavin-based antigens
Meermeier, Erin W., Laugel, Bruno F., Sewell, Andrew K., Corbett, Alexandra J., Rossjohn, Jamie, McCluskey, James, Harriff, Melanie J., Franks, Tamera, Gold, Marielle C., Lewinsohn, David M.
Published in Nature communications (16.08.2016)
Published in Nature communications (16.08.2016)
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Structural definition of HLA class II-presented SARS-CoV-2 epitopes reveals a mechanism to escape pre-existing CD4+ T cell immunity
Chen, Yuan, Mason, Georgina H., Scourfield, D. Oliver, Greenshields-Watson, Alexander, Haigh, Tracey A., Sewell, Andrew K., Long, Heather M., Gallimore, Awen M., Rizkallah, Pierre, MacLachlan, Bruce J., Godkin, Andrew
Published in Cell reports (Cambridge) (29.08.2023)
Published in Cell reports (Cambridge) (29.08.2023)
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Metabolic Adaptation of Human CD4 + and CD8 + T-Cells to T-Cell Receptor-Mediated Stimulation
Jones, Nicholas, Cronin, James G, Dolton, Garry, Panetti, Silvia, Schauenburg, Andrea J, Galloway, Sarah A E, Sewell, Andrew K, Cole, David K, Thornton, Catherine A, Francis, Nigel J
Published in Frontiers in immunology (09.11.2017)
Published in Frontiers in immunology (09.11.2017)
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Optimized Peptide-MHC Multimer Protocols for Detection and Isolation of Autoimmune T-Cells
Dolton, Garry, Zervoudi, Efthalia, Rius, Cristina, Wall, Aaron, Thomas, Hannah L, Fuller, Anna, Yeo, Lorraine, Legut, Mateusz, Wheeler, Sophie, Attaf, Meriem, Chudakov, Dmitriy M, Choy, Ernest, Peakman, Mark, Sewell, Andrew K
Published in Frontiers in immunology (29.06.2018)
Published in Frontiers in immunology (29.06.2018)
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Different T Cell Receptor Affinity Thresholds and CD8 Coreceptor Dependence Govern Cytotoxic T Lymphocyte Activation and Tetramer Binding Properties
Laugel, Bruno, van den Berg, Hugo A., Gostick, Emma, Cole, David K., Wooldridge, Linda, Boulter, Jonathan, Milicic, Anita, Price, David A., Sewell, Andrew K.
Published in The Journal of biological chemistry (17.08.2007)
Published in The Journal of biological chemistry (17.08.2007)
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Germ Line-governed Recognition of a Cancer Epitope by an Immunodominant Human T-cell Receptor
Cole, David K., Yuan, Fang, Rizkallah, Pierre J., Miles, John J., Gostick, Emma, Price, David A., Gao, George F., Jakobsen, Bent K., Sewell, Andrew K.
Published in The Journal of biological chemistry (02.10.2009)
Published in The Journal of biological chemistry (02.10.2009)
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Induction of influenza-specific local CD8 T-cells in the respiratory tract after aerosol delivery of vaccine antigen or virus in the Babraham inbred pig
Tungatt, Katie, Dolton, Garry, Morgan, Sophie B, Attaf, Meriem, Fuller, Anna, Whalley, Thomas, Hemmink, Johanneke D, Porter, Emily, Szomolay, Barbara, Montoya, Maria, Hammond, John A, Miles, John J, Cole, David K, Townsend, Alain, Bailey, Mick, Rizkallah, Pierre J, Charleston, Bryan, Tchilian, Elma, Sewell, Andrew K
Published in PLoS pathogens (01.05.2018)
Published in PLoS pathogens (01.05.2018)
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Nonstimulatory peptide–MHC enhances human T-cell antigen-specific responses by amplifying proximal TCR signaling
Zhao, Xiang, Sankaran, Shvetha, Yap, Jiawei, Too, Chien Tei, Ho, Zi Zong, Dolton, Garry, Legut, Mateusz, Ren, Ee Chee, Sewell, Andrew K., Bertoletti, Antonio, MacAry, Paul A., Brzostek, Joanna, Gascoigne, Nicholas R. J.
Published in Nature communications (13.07.2018)
Published in Nature communications (13.07.2018)
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Peptide length determines the outcome of TCR/peptide-MHCI engagement
Ekeruche-Makinde, Julia, Miles, John J., van den Berg, Hugo A., Skowera, Ania, Cole, David K., Dolton, Garry, Schauenburg, Andrea J.A., Tan, Mai Ping, Pentier, Johanne M., Llewellyn-Lacey, Sian, Miles, Kim M., Bulek, Anna M., Clement, Mathew, Williams, Tamsin, Trimby, Andrew, Bailey, Mick, Rizkallah, Pierre, Rossjohn, Jamie, Peakman, Mark, Price, David A., Burrows, Scott R., Sewell, Andrew K., Wooldridge, Linda
Published in Blood (14.02.2013)
Published in Blood (14.02.2013)
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Human TCR-Binding Affinity is Governed by MHC Class Restriction
Cole, David K, Pumphrey, Nicholas J, Boulter, Jonathan M, Sami, Malkit, Bell, John I, Gostick, Emma, Price, David A, Gao, George F, Sewell, Andrew K, Jakobsen, Bent K
Published in Journal of Immunology (01.05.2007)
Published in Journal of Immunology (01.05.2007)
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The molecular determinants of CD8 co‐receptor function
Cole, David K., Laugel, Bruno, Clement, Mathew, Price, David A., Wooldridge, Linda, Sewell, Andrew K.
Published in Immunology (01.10.2012)
Published in Immunology (01.10.2012)
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Distortion of the Major Histocompatibility Complex Class I Binding Groove to Accommodate an Insulin-derived 10-Mer Peptide
Motozono, Chihiro, Pearson, James A., De Leenheer, Evy, Rizkallah, Pierre J., Beck, Konrad, Trimby, Andrew, Sewell, Andrew K., Wong, F. Susan, Cole, David K.
Published in The Journal of biological chemistry (31.07.2015)
Published in The Journal of biological chemistry (31.07.2015)
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Profound Inhibition of Antigen-Specific T-Cell Effector Functions by Dasatinib
Weichsel, Ralf, Dix, Carolin, Wooldridge, Linda, Clement, Matthew, Fenton-May, Angharad, Sewell, Andrew K, Zezula, Josef, Greiner, Elisabeth, Gostick, Emma, Price, David A, Einsele, Hermann, Seggewiss, Ruth
Published in Clinical cancer research (15.04.2008)
Published in Clinical cancer research (15.04.2008)
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Cytomegalovirus-Mediated T Cell Receptor Repertoire Perturbation Is Present in Early Life
Attaf, Meriem, Roider, Julia, Malik, Amna, Rius Rafael, Cristina, Dolton, Garry, Predergast, Andrew J, Leslie, Alasdair, Ndung'u, Thumbi, Kløverpris, Henrik N, Sewell, Andrew K, Goulder, Philip J
Published in Frontiers in immunology (30.09.2020)
Published in Frontiers in immunology (30.09.2020)
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Major TCR Repertoire Perturbation by Immunodominant HLA-B44:03-Restricted CMV-Specific T Cells
Attaf, Meriem, Malik, Amna, Severinsen, Mai C., Roider, Julia, Ogongo, Paul, Buus, Søren, Ndung'u, Thumbi, Leslie, Alasdair, Kløverpris, Henrik N., Matthews, Philippa C., Sewell, Andrew K., Goulder, Philip
Published in Frontiers in immunology (14.11.2018)
Published in Frontiers in immunology (14.11.2018)
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GPU-Accelerated Discovery of Pathogen-Derived Molecular Mimics of a T-Cell Insulin Epitope
Whalley, Thomas, Dolton, Garry, Brown, Paul E, Wall, Aaron, Wooldridge, Linda, van den Berg, Hugo, Fuller, Anna, Hopkins, Jade R, Crowther, Michael D, Attaf, Meriem, Knight, Robin R, Cole, David K, Peakman, Mark, Sewell, Andrew K, Szomolay, Barbara
Published in Frontiers in immunology (28.02.2020)
Published in Frontiers in immunology (28.02.2020)
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