Proteome activity landscapes of tumor cell lines determine drug responses
Frejno, Martin, Meng, Chen, Ruprecht, Benjamin, Oellerich, Thomas, Scheich, Sebastian, Kleigrewe, Karin, Drecoll, Enken, Samaras, Patroklos, Hogrebe, Alexander, Helm, Dominic, Mergner, Julia, Zecha, Jana, Heinzlmeir, Stephanie, Wilhelm, Mathias, Dorn, Julia, Kvasnicka, Hans-Michael, Serve, Hubert, Weichert, Wilko, Kuster, Bernhard
Published in Nature communications (20.07.2020)
Published in Nature communications (20.07.2020)
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Midostaurin plus Chemotherapy for Acute Myeloid Leukemia with a FLT3 Mutation
Stone, Richard M, Mandrekar, Sumithra J, Sanford, Ben L, Laumann, Kristina, Geyer, Susan, Bloomfield, Clara D, Thiede, Christian, Prior, Thomas W, Döhner, Konstanze, Marcucci, Guido, Lo-Coco, Francesco, Klisovic, Rebecca B, Wei, Andrew, Sierra, Jorge, Sanz, Miguel A, Brandwein, Joseph M, de Witte, Theo, Niederwieser, Dietger, Appelbaum, Frederick R, Medeiros, Bruno C, Tallman, Martin S, Krauter, Jürgen, Schlenk, Richard F, Ganser, Arnold, Serve, Hubert, Ehninger, Gerhard, Amadori, Sergio, Larson, Richard A, Döhner, Hartmut
Published in The New England journal of medicine (03.08.2017)
Published in The New England journal of medicine (03.08.2017)
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Loss of the histone methyltransferase EZH2 induces resistance to multiple drugs in acute myeloid leukemia
Göllner, Stefanie, Oellerich, Thomas, Agrawal-Singh, Shuchi, Schenk, Tino, Klein, Hans-Ulrich, Rohde, Christian, Pabst, Caroline, Sauer, Tim, Lerdrup, Mads, Tavor, Sigal, Stölzel, Friedrich, Herold, Sylvia, Ehninger, Gerhard, Köhler, Gabriele, Pan, Kuan-Ting, Urlaub, Henning, Serve, Hubert, Dugas, Martin, Spiekermann, Karsten, Vick, Binje, Jeremias, Irmela, Berdel, Wolfgang E, Hansen, Klaus, Zelent, Arthur, Wickenhauser, Claudia, Müller, Lutz P, Thiede, Christian, Müller-Tidow, Carsten
Published in Nature medicine (01.01.2017)
Published in Nature medicine (01.01.2017)
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A novel hierarchical prognostic model of AML solely based on molecular mutations
Grossmann, Vera, Schnittger, Susanne, Kohlmann, Alexander, Eder, Christiane, Roller, Andreas, Dicker, Frank, Schmid, Christoph, Wendtner, Clemens-Martin, Staib, Peter, Serve, Hubert, Kreuzer, Karl-Anton, Kern, Wolfgang, Haferlach, Torsten, Haferlach, Claudia
Published in Blood (11.10.2012)
Published in Blood (11.10.2012)
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Outcome of relapsed adult lymphoblastic leukemia depends on response to salvage chemotherapy, prognostic factors, and performance of stem cell transplantation
Gökbuget, Nicola, Stanze, Daniel, Beck, Joachim, Diedrich, Helmut, Horst, Heinz-August, Hüttmann, Andreas, Kobbe, Guido, Kreuzer, Karl-Anton, Leimer, Lothar, Reichle, Albrecht, Schaich, Markus, Schwartz, Stefan, Serve, Hubert, Starck, Michael, Stelljes, Matthias, Stuhlmann, Reingard, Viardot, Andreas, Wendelin, Knut, Freund, Mathias, Hoelzer, Dieter
Published in Blood (06.09.2012)
Published in Blood (06.09.2012)
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A proof of concept phase I/II pilot trial of LSD1 inhibition by tranylcypromine combined with ATRA in refractory/relapsed AML patients not eligible for intensive therapy
Wass, Maxi, Göllner, Stefanie, Besenbeck, Birgit, Schlenk, Richard F., Mundmann, Petra, Göthert, Joachim R., Noppeney, Richard, Schliemann, Christoph, Mikesch, Jan-Henrik, Lenz, Georg, Dugas, Martin, Wermke, Martin, Röllig, Christoph, Bornhäuser, Martin, Serve, Hubert, Platzbecker, Uwe, Foerster, Kathrin I., Burhenne, Jürgen, Haefeli, Walter E., Müller, Lutz P., Binder, Mascha, Pabst, Caroline, Müller-Tidow, Carsten
Published in Leukemia (01.03.2021)
Published in Leukemia (01.03.2021)
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Sorafenib in Combination With Intensive Chemotherapy in Elderly Patients With Acute Myeloid Leukemia: Results From a Randomized, Placebo-Controlled Trial
SERVE, Hubert, KRUG, Utz, FISCHER, Thomas, GIAGOUNIDIS, Aristoteles, NEUBAUER, Andreas, REICHLE, Albrecht, AULITZKY, Walter, NOPPENEY, Richard, BLAU, Igor, KUNZMANN, Volker, STUHLMANN, Reingard, KRÄMER, Alwin, WAGNER, Ruth, KREUZER, Karl-Anton, BRANDTS, Christian, STEFFEN, Björn, THIEDE, Christian, MÜLLER-TIDOW, Carsten, EHNINGER, Gerhard, BERDEL, Wolfgang E, SAUERLAND, M. Cristina, HEINECKE, Achim, BRUNNBERG, Uta, SCHAICH, Markus, OTTMANN, Oliver, DUYSTER, Justus, WANDT, Hannes
Published in Journal of clinical oncology (01.09.2013)
Published in Journal of clinical oncology (01.09.2013)
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Midostaurin reduces relapse in FLT3-mutant acute myeloid leukemia: the Alliance CALGB 10603/RATIFY trial
Larson, Richard A., Mandrekar, Sumithra J., Huebner, Lucas J., Sanford, Ben L., Laumann, Kristina, Geyer, Susan, Bloomfield, Clara D., Thiede, Christian, Prior, Thomas W., Döhner, Konstanze, Marcucci, Guido, Voso, Maria Teresa, Klisovic, Rebecca B., Galinsky, Ilene, Wei, Andrew H., Sierra, Jorge, Sanz, Miguel A., Brandwein, Joseph M., de Witte, Theo, Niederwieser, Dietger, Appelbaum, Frederick R., Medeiros, Bruno C., Tallman, Martin S., Krauter, Jürgen, Schlenk, Richard F., Ganser, Arnold, Serve, Hubert, Ehninger, Gerhard, Amadori, Sergio, Gathmann, Insa, Döhner, Hartmut, Stone, Richard M.
Published in Leukemia (01.09.2021)
Published in Leukemia (01.09.2021)
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MALAT-1, a novel noncoding RNA, and thymosin β4 predict metastasis and survival in early-stage non-small cell lung cancer
PING JI, DIEDERICHS, Sven, THOMAS, Michael, BERDEL, Wolfgang E, SERVE, Hubert, MÜLLER-TIDOW, Carsten, WENBING WANG, BÖING, Sebastian, METZGER, Ralf, SCHNEIDER, Paul M, TIDOW, Nicola, BRANDT, Burkhard, BUERGER, Horst, BULK, Etmar
Published in Oncogene (11.09.2003)
Published in Oncogene (11.09.2003)
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Long-term survival after intensive chemotherapy or hypomethylating agents in AML patients aged 70 years and older: a large patient data set study from European registries
Récher, Christian, Röllig, Christoph, Bérard, Emilie, Bertoli, Sarah, Dumas, Pierre-Yves, Tavitian, Suzanne, Kramer, Michael, Serve, Hubert, Bornhäuser, Martin, Platzbecker, Uwe, Müller-Tidow, Carsten, Baldus, Claudia D., Martínez-Cuadrón, David, Serrano, Josefina, Martínez-Sánchez, Pilar, Arbolí, Eduardo Rodríguez, Gil, Cristina, Bergua, Juan, Bernal, Teresa, de la Fuente Burguera, Adolfo, Delabesse, Eric, Bidet, Audrey, Pigneux, Arnaud, Montesinos, Pau
Published in Leukemia (01.04.2022)
Published in Leukemia (01.04.2022)
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Colonization with multidrug resistant organisms determines the clinical course of patients with acute myeloid leukemia undergoing intensive induction chemotherapy
Ballo, Olivier, Tarazzit, Ikram, Stratmann, Jan, Reinheimer, Claudia, Hogardt, Michael, Wichelhaus, Thomas A, Kempf, Volkhard, Serve, Hubert, Finkelmeier, Fabian, Brandts, Christian
Published in PloS one (23.01.2019)
Published in PloS one (23.01.2019)
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LSD1 inhibition by tranylcypromine derivatives interferes with GFI1-mediated repression of PU.1 target genes and induces differentiation in AML
Barth, Jessica, Abou-El-Ardat, Khalil, Dalic, Denis, Kurrle, Nina, Maier, Anna-Maria, Mohr, Sebastian, Schütte, Judith, Vassen, Lothar, Greve, Gabriele, Schulz-Fincke, Johannes, Schmitt, Martin, Tosic, Milica, Metzger, Eric, Bug, Gesine, Khandanpour, Cyrus, Wagner, Sebastian A., Lübbert, Michael, Jung, Manfred, Serve, Hubert, Schüle, Roland, Berg, Tobias
Published in Leukemia (01.06.2019)
Published in Leukemia (01.06.2019)
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COVID-19 in multiple-myeloma patients: cellular and humoral immunity against SARS-CoV-2 in a short- and long-term view
von Metzler, Ivana, Campe, Julia, Huenecke, Sabine, Raab, Marc S., Goldschmidt, Hartmut, Schubert, Ralf, Rabenau, Holger F., Ciesek, Sandra, Serve, Hubert, Ullrich, Evelyn
Published in Journal of molecular medicine (Berlin, Germany) (01.03.2022)
Published in Journal of molecular medicine (Berlin, Germany) (01.03.2022)
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Metabolic Plasticity of Acute Myeloid Leukemia
Kreitz, Johanna, Schönfeld, Christine, Seibert, Marcel, Stolp, Verena, Alshamleh, Islam, Oellerich, Thomas, Steffen, Björn, Schwalbe, Harald, Schnütgen, Frank, Kurrle, Nina, Serve, Hubert
Published in Cells (Basel, Switzerland) (31.07.2019)
Published in Cells (Basel, Switzerland) (31.07.2019)
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Hoxa9 and Meis1 Cooperatively Induce Addiction to Syk Signaling by Suppressing miR-146a in Acute Myeloid Leukemia
Mohr, Sebastian, Doebele, Carmen, Comoglio, Federico, Berg, Tobias, Beck, Julia, Bohnenberger, Hanibal, Alexe, Gabriela, Corso, Jasmin, Ströbel, Philipp, Wachter, Astrid, Beissbarth, Tim, Schnütgen, Frank, Cremer, Anjali, Haetscher, Nadine, Göllner, Stefanie, Rouhi, Arefeh, Palmqvist, Lars, Rieger, Michael A., Schroeder, Timm, Bönig, Halvard, Müller-Tidow, Carsten, Kuchenbauer, Florian, Schütz, Ekkehard, Green, Anthony R., Urlaub, Henning, Stegmaier, Kimberly, Humphries, R. Keith, Serve, Hubert, Oellerich, Thomas
Published in Cancer cell (10.04.2017)
Published in Cancer cell (10.04.2017)
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Journal Article
Blast vacuolization in AML patients indicates adverse-risk AML and is associated with impaired survival after intensive induction chemotherapy
Ballo, Olivier, Stratmann, Jan, Serve, Hubert, Steffen, Björn, Finkelmeier, Fabian, Brandts, Christian
Published in PloS one (30.09.2019)
Published in PloS one (30.09.2019)
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Genomic CDKN2A/2B deletions in adult Ph+ ALL are adverse despite allogeneic stem cell transplantation
Pfeifer, Heike, Raum, Katharina, Markovic, Sandra, Nowak, Verena, Fey, Stephanie, Obländer, Julia, Pressler, Jovita, Böhm, Verena, Brüggemann, Monika, Wunderle, Lydia, Hüttmann, Andreas, Wäsch, Ralph, Beck, Joachim, Stelljes, Matthias, Viardot, Andreas, Lang, Fabian, Hoelzer, Dieter, Hofmann, Wolf-Karsten, Serve, Hubert, Weiss, Christel, Goekbuget, Nicola, Ottmann, Oliver G., Nowak, Daniel
Published in Blood (29.03.2018)
Published in Blood (29.03.2018)
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CMR imaging biosignature of cardiac involvement due to cancer-related treatment by T1 and T2 mapping
Haslbauer, Jasmin D., Lindner, Sarah, Valbuena-Lopez, Silvia, Zainal, Hafisyatul, Zhou, Hui, D'Angelo, Tommaso, Pathan, Faraz, Arendt, Christophe A., Bug, Gesine, Serve, Hubert, Vogl, Thomas J., Zeiher, Andreas M., Carr-White, Gerry, Nagel, Eike, Puntmann, Valentina O.
Published in International journal of cardiology (15.01.2019)
Published in International journal of cardiology (15.01.2019)
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Selective inactivation of hypomethylating agents by SAMHD1 provides a rationale for therapeutic stratification in AML
Oellerich, Thomas, Schneider, Constanze, Thomas, Dominique, Knecht, Kirsten M., Buzovetsky, Olga, Kaderali, Lars, Schliemann, Christoph, Bohnenberger, Hanibal, Angenendt, Linus, Hartmann, Wolfgang, Wardelmann, Eva, Rothenburger, Tamara, Mohr, Sebastian, Scheich, Sebastian, Comoglio, Federico, Wilke, Anne, Ströbel, Philipp, Serve, Hubert, Michaelis, Martin, Ferreirós, Nerea, Geisslinger, Gerd, Xiong, Yong, Keppler, Oliver T., Cinatl, Jindrich
Published in Nature communications (02.08.2019)
Published in Nature communications (02.08.2019)
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