2- and 3-Substituted 1,4-Naphthoquinone Derivatives as Subversive Substrates of Trypanothione Reductase and Lipoamide Dehydrogenase from Trypanosoma cruzi: Synthesis and Correlation between Redox Cycling Activities and in Vitro Cytotoxicity
SALMON-CHEMIN, Laurence, BUISINE, Eric, YARDLEY, Vanessa, KOHLER, Sven, DEBREU, Marie-Ange, LANDRY, Valérie, SERGHERAERT, Christian, CROFT, Simon L., KRAUTH-SIEGEL, R. Luise, DAVIOUD-CHARVET, Elisabeth
Published in Journal of medicinal chemistry (15.02.2001)
Published in Journal of medicinal chemistry (15.02.2001)
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A Prodrug Form of a Plasmodium falciparum Glutathione Reductase Inhibitor Conjugated with a 4-Anilinoquinoline
Davioud-Charvet, Elisabeth, Delarue, Sandrine, Biot, Christophe, Schwöbel, Babett, Boehme, Catharina C, Müssigbrodt, Andreas, Maes, Louis, Sergheraert, Christian, Grellier, Philippe, Schirmer, R. Heiner, Becker, Katja
Published in Journal of medicinal chemistry (22.11.2001)
Published in Journal of medicinal chemistry (22.11.2001)
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Trypanosoma cruzi Prolyl Oligopeptidase Tc80 Is Involved in Nonphagocytic Mammalian Cell Invasion by Trypomastigotes
Grellier, Philippe, Vendeville, Sandrine, Joyeau, Roger, Bastos, Izabela M.D., Drobecq, Hervé, Frappier, François, Teixeira, Antonio R.L., Schrével, Joseph, Davioud-Charvet, Elisabeth, Sergheraert, Christian, Santana, Jaime M.
Published in The Journal of biological chemistry (14.12.2001)
Published in The Journal of biological chemistry (14.12.2001)
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Synthesis and in Vitro and in Vivo Antimalarial Activity of New 4-Anilinoquinolines
Delarue, Sandrine, Girault, Sophie, Maes, Louis, Debreu-Fontaine, Marie-Ange, Labaeïd, Mehdi, Grellier, Philippe, Sergheraert, Christian
Published in Journal of medicinal chemistry (16.08.2001)
Published in Journal of medicinal chemistry (16.08.2001)
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Parallel Synthesis and Anti-Malarial Activity of a Sulfonamide Library
Ryckebusch, A, Déprez-Poulain, R, Debreu-Fontaine, M.-A, Vandaele, R, Mouray, E, Grellier, P, Sergheraert, C
Published in Bioorganic & medicinal chemistry letters (16.09.2002)
Published in Bioorganic & medicinal chemistry letters (16.09.2002)
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Antiplasmodial Activity and Cytotoxicity of Bis-, Tris-, and Tetraquinolines with Linear or Cyclic Amino Linkers
Girault, Sophie, Grellier, Philippe, Berecibar, Amaya, Maes, Louis, Lemière, Pascal, Mouray, Elisabeth, Davioud-Charvet, Elisabeth, Sergheraert, Christian
Published in Journal of medicinal chemistry (24.05.2001)
Published in Journal of medicinal chemistry (24.05.2001)
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Lacrimal gland PKC isoforms are differentially involved in agonist-induced protein secretion
Zoukhri, D, Hodges, R R, Sergheraert, C, Toker, A, Dartt, D A
Published in The American journal of physiology (01.01.1997)
Published in The American journal of physiology (01.01.1997)
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Synthetic hispidin, a PKC inhibitor, is more cytotoxic toward cancer cells than normal cells in vitro
GONINDARD, C, BERGONZI, C, DENIER, C, SERGHERAERT, C, KLAEBE, A, CHAVANT, L, HOLLANDE, E
Published in Cell biology and toxicology (01.03.1997)
Published in Cell biology and toxicology (01.03.1997)
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Design, synthesis and antimalarial activity of a glyoxylylhydrazone library
Ryckebusch, A., Fruchart, J.-S., Cattiaux, L., Rousselot-Paillet, P., Leroux, V., Melnyk, O., Grellier, P., Mouray, E., Sergheraert, C., Melnyk, P.
Published in Bioorganic & medicinal chemistry letters (06.09.2004)
Published in Bioorganic & medicinal chemistry letters (06.09.2004)
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Purification and characterization of a trypanothione-glutathione thioltransferase from Trypanosoma cruzi
Moutiez, M, Aumercier, M, Schöneck, R, Meziane-Cherif, D, Lucas, V, Aumercier, P, Ouaissi, A, Sergheraert, C, Tartar, A
Published in Biochemical journal (01.09.1995)
Published in Biochemical journal (01.09.1995)
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Antimalarial in-vivo activity of bis(9-amino-6-chloro-2-methoxyacridines)
Girault, S, Delarue, S, Grellier, P, Berecibar, A, Maes, L, Quirijnen, L, Lemiere, P, Debreu-Fontaine, MA, Sergheraert, C
Published in Journal of pharmacy and pharmacology (01.07.2001)
Published in Journal of pharmacy and pharmacology (01.07.2001)
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Synthesis and anti-HIV evaluation of D4T and D4T 5'-monophosphate prodrugs
Sergheraert, C, Pierlot, C, Tartar, A, Henin, Y, Lemaitre, M
Published in Journal of medicinal chemistry (02.04.1993)
Published in Journal of medicinal chemistry (02.04.1993)
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Reduction of a Trisulfide Derivative of Glutathione by Glutathione Reductase
Moutiez, M., Aumercier, M., Teissier, E., Parmentier, B., Tartar, A., Sergheraert, C.
Published in Biochemical and biophysical research communications (15.08.1994)
Published in Biochemical and biophysical research communications (15.08.1994)
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Design of potent protein kinase inhibitors using the bisubstrate approach
RICOUART, A, GESQUIERE, J. C, TARTAR, A, SERGHERAERT, C
Published in Journal of medicinal chemistry (1991)
Published in Journal of medicinal chemistry (1991)
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Preparation of trisulfide derivatives of cystine and their formation as by-products during peptide synthesis
Parmentier, B., Moutiez, M., Tartar, A., Sergheraert, C.
Published in Tetrahedron letters (23.05.1994)
Published in Tetrahedron letters (23.05.1994)
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Phorbol ester-stimulated exocytosis in lacrimal gland: PKC might not be the sole effector
Zoukhri, D, Sergheraert, C, Rossignol, B
Published in The American journal of physiology (01.04.1993)
Published in The American journal of physiology (01.04.1993)
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