Preliminary in Vitro Assessment of the Potential of EST64454, a Sigma-1 Receptor Antagonist, for Pharmacokinetic Drug–Drug Interactions
Yeste, Sandra, Reinoso, Raquel F., Ayet, Eva, Pretel, Maria José, Balada, Ariadna, Serafini, Maria Teresa
Published in Biological & pharmaceutical bulletin (01.01.2020)
Published in Biological & pharmaceutical bulletin (01.01.2020)
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Synthesis and Biological Evaluation of the 1-Arylpyrazole Class of sigma(1) Receptor Antagonists: Identification of 4-{2-[5-Methyl-1-(naphthalen-2-yl)-1H-pyrazol-3-yloxy]ethyl}morpholine (S1RA, E-52862)
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Published in Journal of medicinal chemistry (11.10.2012)
Published in Journal of medicinal chemistry (11.10.2012)
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Synthesis and Biological Evaluation of the 1‑Arylpyrazole Class of σ1 Receptor Antagonists: Identification of 4‑{2-[5-Methyl-1-(naphthalen-2-yl)‑1H‑pyrazol-3-yloxy]ethyl}morpholine (S1RA, E‑52862)
Díaz, José Luis, Cuberes, Rosa, Berrocal, Joana, Contijoch, Montserrat, Christmann, Ute, Fernández, Ariadna, Port, Adriana, Holenz, Jörg, Buschmann, Helmut, Laggner, Christian, Serafini, Maria Teresa, Burgueño, Javier, Zamanillo, Daniel, Merlos, Manuel, Vela, José Miguel, Almansa, Carmen
Published in Journal of medicinal chemistry (11.10.2012)
Published in Journal of medicinal chemistry (11.10.2012)
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4‑Aryl-1-oxa-4,9-diazaspiro[5.5]undecane Derivatives as Dual μ‑Opioid Receptor Agonists and σ1 Receptor Antagonists for the Treatment of Pain
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Published in Journal of medicinal chemistry (12.03.2020)
Published in Journal of medicinal chemistry (12.03.2020)
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Comparative In vitro Metabolism of Enflicoxib in Dogs, Rats, and Humans: Main Metabolites and Proposed Metabolic Pathways
Solà, Josep, Menargues, Àngel, Homedes, Josep, Salichs, Marta, Serafini, Maria Teresa, Encina, Gregorio
Published in Drug metabolism letters (2021)
Published in Drug metabolism letters (2021)
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Bispecific sigma-1 receptor antagonism and mu-opioid receptor partial agonism: WLB-73502, an analgesic with improved efficacy and safety profile compared to strong opioids
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Published in Acta pharmaceutica Sinica. B (01.01.2023)
Published in Acta pharmaceutica Sinica. B (01.01.2023)
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4-Aryl-1-oxa-4,9-diazaspiro[5.5]undecane Derivatives as Dual mu-Opioid Receptor Agonists and sigma(1) Receptor Antagonists for the Treatment of Pain
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Published in Journal of medicinal chemistry (12.03.2020)
Published in Journal of medicinal chemistry (12.03.2020)
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Preliminary in vitro approach to evaluate the drug-drug interaction potential of EST73502, a dual µ-opioid receptor partial agonist and σ1 receptor antagonist
Ayet, Eva, Yeste, Sandra, Reinoso, Raquel F., Pretel, María José, Balada, Ariadna, Serafini, Maria Teresa
Published in Xenobiotica (04.05.2021)
Published in Xenobiotica (04.05.2021)
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Preliminary in vitro assessment of pharmacokinetic drug-drug interactions of EST64401 and EST64514, two sigma-1 receptor antagonists
Reinoso, Raquel F., Yeste, Sandra, Ayet, Eva, Pretel, María José, Balada, Ariadna, Serafini, Maria Teresa
Published in Xenobiotica (03.04.2021)
Published in Xenobiotica (03.04.2021)
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Synthesis and Biological Evaluation of the 1-Arylpyrazole Class of σ 1 Receptor Antagonists: Identification of 4-{2-[5-Methyl-1-(naphthalen-2-yl)-1 H -pyrazol-3-yloxy]ethyl}morpholine (S1RA, E-52862)
Díaz, José Luis, Cuberes, Rosa, Berrocal, Joana, Contijoch, Montserrat, Christmann, Ute, Fernández, Ariadna, Port, Adriana, Holenz, Jörg, Buschmann, Helmut, Laggner, Christian, Serafini, Maria Teresa, Burgueño, Javier, Zamanillo, Daniel, Merlos, Manuel, Vela, José Miguel, Almansa, Carmen
Published in Journal of medicinal chemistry (11.10.2012)
Published in Journal of medicinal chemistry (11.10.2012)
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4-Aryl-1-oxa-4,9-diazaspiro[5.5]undecane Derivatives as Dual μ-Opioid Receptor Agonists and σ 1 Receptor Antagonists for the Treatment of Pain
García, Mónica, Virgili, Marina, Alonso, Mònica, Alegret, Carles, Fernández, Begoña, Port, Adriana, Pascual, Rosalía, Monroy, Xavier, Vidal-Torres, Alba, Serafini, María-Teresa, Vela, José Miguel, Almansa, Carmen
Published in Journal of medicinal chemistry (12.03.2020)
Published in Journal of medicinal chemistry (12.03.2020)
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A Medicinal-Chemistry-Guided Approach to Selective and Druglike Sigma 1 Ligands
Corbera, Jordi, Vaño, David, Martínez, Daniel, Vela, José M., Zamanillo, Daniel, Dordal, Alberto, Andreu, Francesc, Hernandez, Enric, Perez, Raquel, Escriche, Marisol, Salgado, Leonardo, Yeste, Sandra, Serafini, Maria Teresa, Pascual, Rosalia, Alegre, Júlia, Calvet, Maria Carme, Cano, Núria, Carro, Mónica, Buschmann, Helmut, Holenz, Jörg
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Published in ChemMedChem (01.01.2006)
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Published in Bioorganic & medicinal chemistry letters (2005)
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Published in Bioorganic & medicinal chemistry letters (2005)
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A preliminary study of the metabolic stability of a series of benzoxazinone derivatives as potent neuropeptide Y5 antagonists
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Year of Publication 27.02.2018
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