Neuron-specific signatures in the chromosomal connectome associated with schizophrenia risk
Rajarajan, Prashanth, Borrman, Tyler, Liao, Will, Schrode, Nadine, Flaherty, Erin, Casiño, Charlize, Powell, Samuel, Yashaswini, Chittampalli, LaMarca, Elizabeth A, Kassim, Bibi, Javidfar, Behnam, Espeso-Gil, Sergio, Li, Aiqun, Won, Hyejung, Geschwind, Daniel H, Ho, Seok-Man, MacDonald, Matthew, Hoffman, Gabriel E, Roussos, Panos, Zhang, Bin, Hahn, Chang-Gyu, Weng, Zhiping, Brennand, Kristen J, Akbarian, Schahram
Published in Science (American Association for the Advancement of Science) (14.12.2018)
Published in Science (American Association for the Advancement of Science) (14.12.2018)
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Synergistic effects of common schizophrenia risk variants
Schrode, Nadine, Ho, Seok-Man, Yamamuro, Kazuhiko, Dobbyn, Amanda, Huckins, Laura, Matos, Marliette R., Cheng, Esther, Deans, P. J. Michael, Flaherty, Erin, Barretto, Natalie, Topol, Aaron, Alganem, Khaled, Abadali, Sonya, Gregory, James, Hoelzli, Emily, Phatnani, Hemali, Singh, Vineeta, Girish, Deeptha, Aronow, Bruce, Mccullumsmith, Robert, Hoffman, Gabriel E., Stahl, Eli A., Morishita, Hirofumi, Sklar, Pamela, Brennand, Kristen J.
Published in Nature genetics (01.10.2019)
Published in Nature genetics (01.10.2019)
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Transformative Network Modeling of Multi-omics Data Reveals Detailed Circuits, Key Regulators, and Potential Therapeutics for Alzheimer’s Disease
Wang, Minghui, Li, Aiqun, Sekiya, Michiko, Beckmann, Noam D., Quan, Xiuming, Schrode, Nadine, Fernando, Michael B., Yu, Alex, Zhu, Li, Cao, Jiqing, Lyu, Liwei, Horgusluoglu, Emrin, Wang, Qian, Guo, Lei, Wang, Yuan-shuo, Neff, Ryan, Song, Won-min, Wang, Erming, Shen, Qi, Zhou, Xianxiao, Ming, Chen, Ho, Seok-Man, Vatansever, Sezen, Kaniskan, H. Ümit, Jin, Jian, Zhou, Ming-Ming, Ando, Kanae, Ho, Lap, Slesinger, Paul A., Yue, Zhenyu, Zhu, Jun, Katsel, Pavel, Gandy, Sam, Ehrlich, Michelle E., Fossati, Valentina, Noggle, Scott, Cai, Dongming, Haroutunian, Vahram, Iijima, Koichi M., Schadt, Eric, Brennand, Kristen J., Zhang, Bin
Published in Neuron (Cambridge, Mass.) (20.01.2021)
Published in Neuron (Cambridge, Mass.) (20.01.2021)
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The methyltransferase SETDB1 regulates a large neuron-specific topological chromatin domain
Jiang, Yan, Loh, Yong-Hwee Eddie, Rajarajan, Prashanth, Hirayama, Teruyoshi, Liao, Will, Kassim, Bibi S, Javidfar, Behnam, Hartley, Brigham J, Kleofas, Lisa, Park, Royce B, Labonte, Benoit, Ho, Seok-Man, Chandrasekaran, Sandhya, Do, Catherine, Ramirez, Brianna R, Peter, Cyril J, C W, Julia T, Safaie, Brian M, Morishita, Hirofumi, Roussos, Panos, Nestler, Eric J, Schaefer, Anne, Tycko, Benjamin, Brennand, Kristen J, Yagi, Takeshi, Shen, Li, Akbarian, Schahram
Published in Nature genetics (01.08.2017)
Published in Nature genetics (01.08.2017)
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Dual Functions of Highly Potent Graphene Derivative–Poly‑l‑Lysine Composites To Inhibit Bacteria and Support Human Cells
Some, Surajit, Ho, Seok-Man, Dua, Pooja, Hwang, Eunhee, Shin, Young Hun, Yoo, HeeJoun, Kang, Jong-Sun, Lee, Dong-ki, Lee, Hyoyoung
Published in ACS nano (28.08.2012)
Published in ACS nano (28.08.2012)
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Induction of dopaminergic neurons for neuronal subtype-specific modeling of psychiatric disease risk
Powell, Samuel K., O’Shea, Callan, Townsley, Kayla, Prytkova, Iya, Dobrindt, Kristina, Elahi, Rahat, Iskhakova, Marina, Lambert, Tova, Valada, Aditi, Liao, Will, Ho, Seok-Man, Slesinger, Paul A., Huckins, Laura M., Akbarian, Schahram, Brennand, Kristen J.
Published in Molecular psychiatry (01.05.2023)
Published in Molecular psychiatry (01.05.2023)
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Integration of CRISPR-engineering and hiPSC-based models of psychiatric genomics
Matos, Marliette R., Ho, Seok-Man, Schrode, Nadine, Brennand, Kristen J.
Published in Molecular and cellular neuroscience (01.09.2020)
Published in Molecular and cellular neuroscience (01.09.2020)
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In utero exposure to maternal smoking is associated with DNA methylation alterations and reduced neuronal content in the developing fetal brain
Chatterton, Zac, Hartley, Brigham J, Seok, Man-Ho, Mendelev, Natalia, Chen, Sean, Milekic, Maria, Rosoklija, Gorazd, Stankov, Aleksandar, Trencevsja-Ivanovska, Iskra, Brennand, Kristen, Ge, Yongchao, Dwork, Andrew J, Haghighi, Fatemeh
Published in Epigenetics & chromatin (26.01.2017)
Published in Epigenetics & chromatin (26.01.2017)
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Evaluating Synthetic Activation and Repression of Neuropsychiatric-Related Genes in hiPSC-Derived NPCs, Neurons, and Astrocytes
Ho, Seok-Man, Hartley, Brigham J., Flaherty, Erin, Rajarajan, Prashanth, Abdelaal, Rawan, Obiorah, Ifeanyi, Barretto, Natalie, Muhammad, Hamza, Phatnani, Hemali P., Akbarian, Schahram, Brennand, Kristen J.
Published in Stem cell reports (08.08.2017)
Published in Stem cell reports (08.08.2017)
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Using the dCas9-KRAB system to repress gene expression in hiPSC-derived NGN2 neurons
Li, Aiqun, Cartwright, Samuel, Yu, Alex, Ho, Seok-Man, Schrode, Nadine, Deans, P.J. Michael, Matos, Marliette R., Garcia, Meilin Fernandez, Townsley, Kayla G., Zhang, Bin, Brennand, Kristen J.
Published in STAR protocols (18.06.2021)
Published in STAR protocols (18.06.2021)
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Activity-Dependent Transcriptional Program in NGN2+ Neurons Enriched for Genetic Risk for Brain-Related Disorders
Ma, Yixuan, Bendl, Jaroslav, Hartley, Brigham J., Fullard, John F., Abdelaal, Rawan, Ho, Seok-Man, Kosoy, Roman, Gochman, Peter, Rapoport, Judith, Hoffman, Gabriel E., Brennand, Kristen J., Roussos, Panos
Published in Biological psychiatry (1969) (15.01.2024)
Published in Biological psychiatry (1969) (15.01.2024)
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ASCL1- and DLX2-induced GABAergic neurons from hiPSC-derived NPCs
Barretto, Natalie, Zhang, Hanwen, Powell, Samuel K., Fernando, Michael B., Zhang, Siwei, Flaherty, Erin K., Ho, Seok-Man, Slesinger, Paul A., Duan, Jubao, Brennand, Kristen J.
Published in Journal of neuroscience methods (15.03.2020)
Published in Journal of neuroscience methods (15.03.2020)
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Cdo suppresses canonical Wnt signalling via interaction with Lrp6 thereby promoting neuronal differentiation
Jeong, Myong-Ho, Ho, Seok-Man, Vuong, Tuan Anh, Jo, Shin-Bum, Liu, Guizhong, Aaronson, Stuart A., Leem, Young-Eun, Kang, Jong-Sun
Published in Nature communications (19.11.2014)
Published in Nature communications (19.11.2014)
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TGF-β-activated Kinase 1 (TAK1) and Apoptosis Signal-regulating Kinase 1 (ASK1) Interact with the Promyogenic Receptor Cdo to Promote Myogenic Differentiation via Activation of p38MAPK Pathway
Tran, Phong, Ho, Seok-Man, Kim, Bok-Geon, Vuong, Tuan Anh, Leem, Young-Eun, Bae, Gyu-Un, Kang, Jong-Sun
Published in The Journal of biological chemistry (06.04.2012)
Published in The Journal of biological chemistry (06.04.2012)
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Small-molecule inhibition of kinesin KIF18A reveals a mitotic vulnerability enriched in chromosomally unstable cancers
Payton, Marc, Belmontes, Brian, Hanestad, Kelly, Moriguchi, Jodi, Chen, Kui, McCarter, John D, Chung, Grace, Ninniri, Maria Stefania, Sun, Jan, Manoukian, Raffi, Chambers, Stuart, Ho, Seok-Man, Kurzeja, Robert J M, Edson, Katheryne Z, Dahal, Upendra P, Wu, Tian, Wannberg, Sharon, Beltran, Pedro J, Canon, Jude, Boghossian, Andrew S, Rees, Matthew G, Ronan, Melissa M, Roth, Jennifer A, Minocherhomji, Sheroy, Bourbeau, Matthew P, Allen, Jennifer R, Coxon, Angela, Tamayo, Nuria A, Hughes, Paul E
Published in Nature cancer (01.01.2024)
Published in Nature cancer (01.01.2024)
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Cdo interacts with APPL1 and activates Akt in myoblast differentiation
Bae, Gyu-Un, Lee, Jae-Rin, Kim, Bok-Geon, Han, Ji-Won, Leem, Young-Eun, Lee, Hey-Jin, Ho, Seok-Man, Hahn, Myong-Joon, Kang, Jong-Sun
Published in Molecular biology of the cell (15.07.2010)
Published in Molecular biology of the cell (15.07.2010)
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