Humanized UGT2 and CYP3A transchromosomic rats for improved prediction of human drug metabolism
Kazuki, Yasuhiro, Kobayashi, Kaoru, Hirabayashi, Masumi, Abe, Satoshi, Kajitani, Naoyo, Kazuki, Kanako, Takehara, Shoko, Takiguchi, Masato, Satoh, Daisuke, Kuze, Jiro, Sakuma, Tetsushi, Kaneko, Takehito, Mashimo, Tomoji, Osamura, Minori, Hashimoto, Mari, Wakatsuki, Riko, Hirashima, Rika, Fujiwara, Ryoichi, Deguchi, Tsuneo, Kurihara, Atsushi, Tsukazaki, Yasuko, Senda, Naoto, Yamamoto, Takashi, Scheer, Nico, Oshimura, Mitsuo
Published in Proceedings of the National Academy of Sciences - PNAS (19.02.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (19.02.2019)
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Modification of single-nucleotide polymorphism in a fully humanized CYP3A mouse by genome editing technology
Abe, Satoshi, Kobayashi, Kaoru, Oji, Asami, Sakuma, Tetsushi, Kazuki, Kanako, Takehara, Shoko, Nakamura, Kazuomi, Okada, Azusa, Tsukazaki, Yasuko, Senda, Naoto, Honma, Kazuhisa, Yamamoto, Takashi, Ikawa, Masahito, Chiba, Kan, Oshimura, Mitsuo, Kazuki, Yasuhiro
Published in Scientific reports (09.11.2017)
Published in Scientific reports (09.11.2017)
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Trans-chromosomic mice containing a human CYP3A cluster for prediction of xenobiotic metabolism in humans
Kazuki, Yasuhiro, Kobayashi, Kaoru, Aueviriyavit, Sasitorn, Oshima, Takeshi, Kuroiwa, Yoshimi, Tsukazaki, Yasuko, Senda, Naoto, Kawakami, Hiroki, Ohtsuki, Sumio, Abe, Satoshi, Takiguchi, Masato, Hoshiya, Hidetoshi, Kajitani, Naoyo, Takehara, Shoko, Kubo, Kinya, Terasaki, Tetsuya, Chiba, Kan, Tomizuka, Kazuma, Oshimura, Mitsuo
Published in Human molecular genetics (01.02.2013)
Published in Human molecular genetics (01.02.2013)
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Knockout of mouse Cyp3a gene enhances synthesis of cholesterol and bile acid in the liver
Hashimoto, Mari, Kobayashi, Kaoru, Watanabe, Mio, Kazuki, Yasuhiro, Takehara, Shoko, Inaba, Asumi, Nitta, Shin-ichiro, Senda, Naoto, Oshimura, Mitsuo, Chiba, Kan
Published in Journal of lipid research (01.08.2013)
Published in Journal of lipid research (01.08.2013)
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Development of a High-Sensitivity Quantitation Method for Arginine Vasopressin by High-Performance Liquid Chromatography Tandem Mass Spectrometry, and Comparison with Quantitative Values by Radioimmunoassay
TSUKAZAKI, Yasuko, SENDA, Naoto, KUBO, Kinya, YAMADA, Shigeru, KUGOH, Hiroyuki, KAZUKI, Yasuhiro, OSHIMURA, Mitsuo
Published in Analytical Sciences (2016)
Published in Analytical Sciences (2016)
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Application of Liquid Chromatography Tandem Mass Spectrometry to Bioanalysis Services: Role of the “GLP (Good Laboratory Practice)-Free” Laboratory
TSUKAZAKI, Yasuko, NAKANO, Hidehiko, SENDA, Naoto
Published in Journal of the Mass Spectrometry Society of Japan (01.08.2009)
Published in Journal of the Mass Spectrometry Society of Japan (01.08.2009)
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Application of Liquid Chromatography Tandem Mass Spectrometry to Bioanalysis Services
TSUKAZAKI, Yasuko, NAKANO, Hidehiko, SENDA, Naoto
Published in Journal of the Mass Spectrometry Society of Japan (01.07.2009)
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Published in Journal of the Mass Spectrometry Society of Japan (01.07.2009)
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Acute Effect of Amitriptyline, Phenobarbital or Cobaltous Chloride on δ-Aminolevulinic Acid Synthetase, Heme Oxygenase and Microsomal Heme Content and Drug Metabolism in Rat Liver
HOSHI, Katsuji, SENDA, Naoto, FUJINO, Sumiko
Published in Japanese journal of pharmacology (01.01.1989)
Published in Japanese journal of pharmacology (01.01.1989)
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Effects of Co-Administration of Monomethylaminoantipyrine and Cobaltous Chloride on Hepatic Glutathione Level and Glutathione-Related Enzyme Activities in Rats
HOSHI, Katsuji, SENDA, Naoto, IGARASHI, Takashi, SATOH, Tetsuo, UENO, Koichi, KITAGAWA, Haruo
Published in Japanese Journal of Pharmacology (1987)
Published in Japanese Journal of Pharmacology (1987)
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