WSX-1 Is Required for the Initiation of Th1 Responses and Resistance to L. major Infection
Yoshida, Hiroki, Hamano, Shinjiro, Senaldi, Giorgio, Covey, Todd, Faggioni, Raffaella, Mu, Sharon, Xia, Min, Wakeham, Andrew C, Nishina, Hiroshi, Potter, Julia, Saris, Chris J.M, Mak, Tak W
Published in Immunity (Cambridge, Mass.) (01.10.2001)
Published in Immunity (Cambridge, Mass.) (01.10.2001)
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Transgenic overexpression of human IL-17E results in eosinophilia, B-lymphocyte hyperplasia, and altered antibody production
Kim, Mee Rhan, Manoukian, Raffi, Yeh, Richard, Silbiger, Scott M., Danilenko, Dimitry M., Scully, Sheila, Sun, Jilin, DeRose, Margaret L., Stolina, Marina, Chang, David, Van, Gwyneth Y., Clarkin, Kristie, Nguyen, Hung Q., Yu, Yan Bin, Jing, Shuqian, Senaldi, Giorgio, Elliott, Gary, Medlock, Eugene S.
Published in Blood (01.10.2002)
Published in Blood (01.10.2002)
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Mechanisms of Inhibition of Collagen-Induced Arthritis by Murine IL-18 Binding Protein
Banda, Nirmal K, Vondracek, Andrea, Kraus, Damian, Dinarello, Charles A, Kim, Soo-Hyun, Bendele, Alison, Senaldi, Giorgio, Arend, William P
Published in The Journal of immunology (1950) (15.02.2003)
Published in The Journal of immunology (1950) (15.02.2003)
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Genetic Evidence for Functional Redundancy of Platelet/Endothelial Cell Adhesion Molecule-1 (PECAM-1): CD31-Deficient Mice Reveal PECAM-1-Dependent and PECAM-1-Independent Functions
Duncan, Gordon S, Andrew, David P, Takimoto, Hiroaki, Kaufman, Stephen A, Yoshida, Hiroki, Spellberg, Jason, Luis de la Pompa, Jose, Elia, Andrew, Wakeham, Andrew, Karan-Tamir, Barbara, Muller, William A, Senaldi, Giorgio, Zukowski, Mark M, Mak, Tak W
Published in The Journal of immunology (1950) (01.03.1999)
Published in The Journal of immunology (1950) (01.03.1999)
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Journal Article
TACI is a TRAF-interacting receptor for TALL-1, a tumor necrosis factor family member involved in B cell regulation
Xia, X Z, Treanor, J, Senaldi, G, Khare, S D, Boone, T, Kelley, M, Theill, L E, Colombero, A, Solovyev, I, Lee, F, McCabe, S, Elliott, R, Miner, K, Hawkins, N, Guo, J, Stolina, M, Yu, G, Wang, J, Delaney, J, Meng, S Y, Boyle, W J, Hsu, H
Published in The Journal of experimental medicine (03.07.2000)
Published in The Journal of experimental medicine (03.07.2000)
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Novel Neurotrophin-1/B Cell-Stimulating Factor-3: A Cytokine of the IL-6 Family
Senaldi, G, Varnum, B C, Sarmiento, U, Starnes, C, Lile, J, Scully, S, Guo, J, Elliott, G, McNinch, J, Shaklee, C L, Freeman, D, Manu, F, Simonet, W S, Boone, T, Chang, M S
Published in Proceedings of the National Academy of Sciences - PNAS (28.09.1999)
Published in Proceedings of the National Academy of Sciences - PNAS (28.09.1999)
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CD44 regulates hematopoietic progenitor distribution, granuloma formation, and tumorigenicity
SCHMITS, R, FILMUS, J, FURLONGER, C, ZAKARIAN, A, SIMARD, J. J. L, OHASHI, P. S, PAIGE, C. J, GUTIERREZ-RAMOS, J. C, MAK, T. W, GERWIN, N, SENALDI, G, KIEFER, F, KUNDIG, T, WAKEHAM, A, SHAHINIAN, A, CATZAVELOS, C, RAK, J
Published in Blood (15.09.1997)
Published in Blood (15.09.1997)
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CD44 Regulates Hematopoietic Progenitor Distribution, Granuloma Formation, and Tumorigenicity
Schmits, Rudolf, Filmus, Jorge, Gerwin, Nicole, Senaldi, Giorgio, Kiefer, Friedemann, Kundig, Thomas, Wakeham, Andrew, Shahinian, Arda, Catzavelos, Charles, Rak, Janusz, Furlonger, Caren, Zakarian, Arsen, Simard, John J.L., Ohashi, Pamela S., Paige, Christopher J., Gutierrez-Ramos, Jose C., Mak, Tak W.
Published in Blood (15.09.1997)
Published in Blood (15.09.1997)
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IL-18-Binding Protein Protects Against Lipopolysaccharide- Induced Lethality and Prevents the Development of Fas/Fas Ligand-Mediated Models of Liver Disease in Mice
Faggioni, Raffaella, Cattley, Russell C, Guo, Jane, Flores, Silvia, Brown, Heather, Qi, Meiying, Yin, Songmei, Hill, David, Scully, Sheila, Chen, Ching, Brankow, David, Lewis, Jeffrey, Baikalov, Claudia, Yamane, Harvey, Meng, Tina, Martin, Frank, Hu, Sylvia, Boone, Tom, Senaldi, Giorgio
Published in The Journal of immunology (1950) (15.11.2001)
Published in The Journal of immunology (1950) (15.11.2001)
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Pulmonary Inflammation Induced by Pseudomonas aeruginosa Lipopolysaccharide, Phospholipase C, and Exotoxin A: Role of Interferon Regulatory Factor 1
WIELAND, Catharina W, SIEGMUND, Britta, SENALDI, Giorgio, VASIL, Michael L, DINARELLO, Charles A, FANTUZZI, Giamila
Published in Infection and Immunity (01.03.2002)
Published in Infection and Immunity (01.03.2002)
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Journal Article
Role of IL-18 in Acute Lung Inflammation
Jordan, Jacqueline A, Guo, Ren-Feng, Yun, Edward C, Sarma, Vidya, Warner, Roscoe L, Crouch, Larry D, Senaldi, Giorgio, Ulich, Thomas R, Ward, Peter A
Published in The Journal of immunology (1950) (15.12.2001)
Published in The Journal of immunology (1950) (15.12.2001)
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Regulatory Effects of Novel Neurotrophin-1/B Cell-Stimulating Factor-3 (Cardiotrophin-Like Cytokine) on B Cell Function
Senaldi, Giorgio, Stolina, Marina, Guo, Jane, Faggioni, Raffaella, McCabe, Susan, Kaufman, Stephen A, Van, Gwyneth, Xu, Weilong, Fletcher, Frederick A, Boone, Thomas, Chang, Ming-Shi, Sarmiento, Ulla, Cattley, Russell C
Published in The Journal of immunology (1950) (01.06.2002)
Published in The Journal of immunology (1950) (01.06.2002)
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U.S. Phase I First-in-human Study of Taletrectinib (DS-6051b/AB-106), a ROS1/TRK Inhibitor, in Patients with Advanced Solid Tumors
Papadopoulos, Kyriakos P, Borazanci, Erkut, Shaw, Alice T, Katayama, Ryohei, Shimizu, Yuki, Zhu, Viola W, Sun, Thomas Yang, Wakelee, Heather A, Madison, Russell, Schrock, Alexa B, Senaldi, Giorgio, Nakao, Naoki, Hanzawa, Hiroyuki, Tachibana, Masaya, Isoyama, Takeshi, Nakamaru, Kenji, Deng, Chenhui, Li, Meijing, Fan, Frank, Zhao, Qinying, Gao, Yanfei, Seto, Takashi, Jänne, Pasi A, Ou, Sai-Hong Ignatius
Published in Clinical cancer research (15.09.2020)
Published in Clinical cancer research (15.09.2020)
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First-in-Human Study of the Safety, Tolerability, Pharmacokinetics, Immunogenicity, and Pharmacodynamics of DS-7011a, an Anti-TLR7 Antagonistic Monoclonal Antibody for the Treatment of Systemic Lupus Erythematosus
Senaldi, Giorgio, Mohan, Aparna, Zhang, Li, Tanaka, Jun, Lin, Yong, Pandya, Grishma, Grossman, Sindee, Urbina, Sarah, Reynolds, Steven H, Hand, Alan H
Published in Journal of clinical pharmacology (22.08.2024)
Published in Journal of clinical pharmacology (22.08.2024)
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Phase 1 Study To Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Multiple Oral Doses of DS-2969b, a Novel GyrB Inhibitor, in Healthy Subjects
Vandell, Alexander G, Inoue, Satoshi, Dennie, Justin, Nagasawa, Yasuo, Gajee, Roohi, Pav, Joe, Zhang, George, Zamora, Cynthia, Masuda, Nobuhisa, Senaldi, Giorgio
Published in Antimicrobial agents and chemotherapy (01.05.2018)
Published in Antimicrobial agents and chemotherapy (01.05.2018)
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Open-Label Single-Dose Study to Assess the Effect of Mild and Moderate Hepatic Impairment on the Pharmacokinetics of Mirogabalin
Duchin, Kenneth, Senaldi, Giorgio, Warren, Vance, Marbury, Thomas, Lasseter, Kenneth, Zahir, Hamim
Published in Clinical drug investigation (01.11.2018)
Published in Clinical drug investigation (01.11.2018)
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A Phase 1 Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single Oral Doses of DS-3801b, a Motilin Receptor Agonist, in Healthy Subjects
Dennie, Justin, Atiee, George, Warren, Vance, Tao, Ben, Morimoto, Kiyoshi, Senaldi, Giorgio
Published in Journal of clinical pharmacology (01.09.2017)
Published in Journal of clinical pharmacology (01.09.2017)
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A Phase I, Single-Ascending-Dose Study in Healthy Subjects to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of DS-2969b, a Novel GyrB Inhibitor
Dennie, Justin, Vandell, Alexander G, Inoue, Satoshi, Gajee, Roohi, Pav, Joseph, Zhang, George, Zamora, Cynthia, Masuda, Nobuhisa, Uchiyama, Minoru, Yamada, Makiko, Senaldi, Giorgio
Published in Journal of clinical pharmacology (01.12.2018)
Published in Journal of clinical pharmacology (01.12.2018)
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A phase 1 safety and bioimaging trial of antibody DS-8895a against EphA2 in patients with advanced or metastatic EphA2 positive cancers
Gan, Hui K., Parakh, Sagun, Lee, F. T., Tebbutt, Niall C., Ameratunga, Malaka, Lee, Sze Ting, O’Keefe, Graeme J., Gong, Sylvia J., Vanrenen, Christine, Caine, Jaren, Giovannetti, Mara, Murone, Carmel, Scott, Fiona E., Guo, Nancy, Burvenich, Ingrid J. G., Paine, Cameron, Macri, Mary J., Kotsuma, Masakatsu, Senaldi, Giorgio, Venhaus, Ralph, Scott, Andrew M.
Published in Investigational new drugs (01.08.2022)
Published in Investigational new drugs (01.08.2022)
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