The Hippo Transducer YAP1 Transforms Activated Satellite Cells and Is a Potent Effector of Embryonal Rhabdomyosarcoma Formation
Tremblay, Annie M., Missiaglia, Edoardo, Galli, Giorgio G., Hettmer, Simone, Urcia, Roby, Carrara, Matteo, Judson, Robert N., Thway, Khin, Nadal, Gema, Selfe, Joanna L., Murray, Graeme, Calogero, Raffaele A., De Bari, Cosimo, Zammit, Peter S., Delorenzi, Mauro, Wagers, Amy J., Shipley, Janet, Wackerhage, Henning, Camargo, Fernando D.
Published in Cancer cell (11.08.2014)
Published in Cancer cell (11.08.2014)
Get full text
Journal Article
Aurora A Kinase Inhibition Destabilizes PAX3-FOXO1 and MYCN and Synergizes with Navitoclax to Induce Rhabdomyosarcoma Cell Death
Ommer, Johannes, Selfe, Joanna L, Wachtel, Marco, O'Brien, Eleanor M, Laubscher, Dominik, Roemmele, Michaela, Kasper, Stephanie, Delattre, Olivier, Surdez, Didier, Petts, Gemma, Kelsey, Anna, Shipley, Janet, Schäfer, Beat W
Published in Cancer research (Chicago, Ill.) (15.02.2020)
Published in Cancer research (Chicago, Ill.) (15.02.2020)
Get full text
Journal Article
Dual Blockade of the PI3K/AKT/mTOR (AZD8055) and RAS/MEK/ERK (AZD6244) Pathways Synergistically Inhibits Rhabdomyosarcoma Cell Growth In Vitro and In Vivo
RENSHAW, Jane, TAYLOR, Kathryn R, SELFE, Joanna L, THWAY, Khin, PIETSCH, Torsten, PEARSON, Andrew D, SHIPLEY, Janet, BISHOP, Ryan, VALENTI, Melanie, DE HAVEN BRANDON, Alexis, GOWAN, Sharon, ECCLES, Suzanne A, RUDDLE, Ruth R, JOHNSON, Louise D, RAYNAUD, Florence I
Published in Clinical cancer research (01.11.2013)
Published in Clinical cancer research (01.11.2013)
Get full text
Journal Article
Germline and Somatic Genetic Variants in the p53 Pathway Interact to Affect Cancer Risk, Progression, and Drug Response
Zhang, Ping, Kitchen-Smith, Isaac, Xiong, Lingyun, Stracquadanio, Giovanni, Brown, Katherine, Richter, Philipp H, Wallace, Marsha D, Bond, Elisabeth, Sahgal, Natasha, Moore, Samantha, Nornes, Svanhild, De Val, Sarah, Surakhy, Mirvat, Sims, David, Wang, Xuting, Bell, Douglas A, Zeron-Medina, Jorge, Jiang, Yanyan, Ryan, Anderson J, Selfe, Joanna L, Shipley, Janet, Kar, Siddhartha, Pharoah, Paul D, Loveday, Chey, Jansen, Rick, Grochola, Lukasz F, Palles, Claire, Protheroe, Andrew, Millar, Val, Ebner, Daniel V, Pagadala, Meghana, Blagden, Sarah P, Maughan, Timothy S, Domingo, Enric, Tomlinson, Ian, Turnbull, Clare, Carter, Hannah, Bond, Gareth L
Published in Cancer research (Chicago, Ill.) (01.04.2021)
Published in Cancer research (Chicago, Ill.) (01.04.2021)
Get full text
Journal Article
Biological Role and Clinical Implications of MYOD1L122R Mutation in Rhabdomyosarcoma
Di Carlo, Daniela, Chisholm, Julia, Kelsey, Anna, Alaggio, Rita, Bisogno, Gianni, Minard-Colin, Veronique, Jenney, Meriel, Dávila Fajardo, Raquel, Merks, Johannes H. M., Shipley, Janet M., Selfe, Joanna L.
Published in Cancers (07.03.2023)
Published in Cancers (07.03.2023)
Get full text
Journal Article
ATR Is a Therapeutic Target in Synovial Sarcoma
Jones, Samuel E, Fleuren, Emmy D G, Frankum, Jessica, Konde, Asha, Williamson, Chris T, Krastev, Dragomir B, Pemberton, Helen N, Campbell, James, Gulati, Aditi, Elliott, Richard, Menon, Malini, Selfe, Joanna L, Brough, Rachel, Pettitt, Stephen J, Niedzwiedz, Wojciech, van der Graaf, Winette T A, Shipley, Janet, Ashworth, Alan, Lord, Christopher J
Published in Cancer research (Chicago, Ill.) (15.12.2017)
Published in Cancer research (Chicago, Ill.) (15.12.2017)
Get full text
Journal Article
Role for the Histone Demethylase KDM4B in Rhabdomyosarcoma via CDK6 and CCNA2: Compensation by KDM4A and Apoptotic Response of Targeting Both KDM4B and KDM4A
Walters, Zoë S, Aladowicz, Ewa, Villarejo-Balcells, Barbara, Nugent, Gary, Selfe, Joanna L, Eve, Paul, Blagg, Julian, Rossanese, Olivia, Shipley, Janet
Published in Cancers (06.04.2021)
Published in Cancers (06.04.2021)
Get full text
Journal Article
Genomic and Epigenetic Changes Drive Aberrant Skeletal Muscle Differentiation in Rhabdomyosarcoma
Pomella, Silvia, Danielli, Sara G, Alaggio, Rita, Breunis, Willemijn B, Hamed, Ebrahem, Selfe, Joanna, Wachtel, Marco, Walters, Zoe S, Schäfer, Beat W, Rota, Rossella, Shipley, Janet M, Hettmer, Simone
Published in Cancers (18.05.2023)
Published in Cancers (18.05.2023)
Get full text
Journal Article
FGF7–FGFR2 autocrine signaling increases growth and chemoresistance of fusion‐positive rhabdomyosarcomas
Milton, Christopher I., Selfe, Joanna, Aladowicz, Ewa, Man, Stella Y. K., Bernauer, Carolina, Missiaglia, Edoardo, Walters, Zoë S., Gatz, Susanne A., Kelsey, Anna, Generali, Melanie, Box, Gary, Valenti, Melanie, Haven‐Brandon, Alexis, Galiwango, David, Hayes, Angela, Clarke, Matthew, Izquierdo, Elisa, Gonzalez De Castro, David, Raynaud, Florence I., Kirkin, Vladimir, Shipley, Janet M.
Published in Molecular oncology (01.03.2022)
Published in Molecular oncology (01.03.2022)
Get full text
Journal Article
Antitumor Activity of Sustained N-Myc Reduction in Rhabdomyosarcomas and Transcriptional Block by Antigene Therapy
TONELLI, Roberto, MCINTYRE, Alan, ASTOLFI, Annalisa, TAYLOR, Kathryn R, SERRAVALLE, Salvatore, BISHOP, Ryan, NANNI, Cristina, VALENTIJN, Linda J, FACCINI, Andrea, LEUSCHNER, Ivo, FORMICA, Serena, REIS-FILHO, Jorge S, CAMERIN, Consuelo, AMBROSINI, Valentina, THWAY, Khin, FRANZONI, Monica, SUMMERSGILL, Brenda, MARCHELLI, Rosangela, HRELIA, Patrizia, CANTELLI-FORTI, Giorgio, FANTI, Stefano, CORRADINI, Roberto, PESSION, Andrea, WALTERS, Zoë S, SHIPLEY, Janet, DI LEO, Korinne, SELFE, Joanna, PURGATO, Stefania, MISSIAGLIA, Edoardo, TORTORI, Andrea, RENSHAW, Jane
Published in Clinical cancer research (01.02.2012)
Published in Clinical cancer research (01.02.2012)
Get full text
Journal Article
Pharmacological EZH2 inhibition combined with retinoic acid treatment promotes differentiation and apoptosis in rhabdomyosarcoma cells
O'Brien, Eleanor, Tse, Carmen, Tracy, Ian, Reddin, Ian, Selfe, Joanna, Gibson, Jane, Tapper, William, Pengelly, Reuben J, Gao, Jinhui, Aladowicz, Ewa, Petts, Gemma, Thway, Khin, Popov, Sergey, Kelsey, Anna, Underwood, Timothy J, Shipley, Janet, Walters, Zoë S
Published in Clinical epigenetics (19.10.2023)
Published in Clinical epigenetics (19.10.2023)
Get full text
Journal Article
Genomic imbalances in rhabdomyosarcoma cell lines affect expression of genes frequently altered in primary tumors: An approach to identify candidate genes involved in tumor development
Missiaglia, Edoardo, Selfe, Joanna, Hamdi, Mohamed, Williamson, Daniel, Schaaf, Gerben, Fang, Cheng, Koster, Jan, Summersgill, Brenda, Messahel, Boo, Versteeg, Rogier, Pritchard-Jones, Kathy, Kool, Marcel, Shipley, Janet
Published in Genes chromosomes & cancer (01.06.2009)
Published in Genes chromosomes & cancer (01.06.2009)
Get full text
Journal Article
Chemosensitivity profiling of osteosarcoma tumour cell lines identifies a model of BRCAness
Holme, Harriett, Gulati, Aditi, Brough, Rachel, Fleuren, Emmy D G, Bajrami, Ilirjana, Campbell, James, Chong, Irene Y, Costa-Cabral, Sara, Elliott, Richard, Fenton, Tim, Frankum, Jessica, Jones, Samuel E, Menon, Malini, Miller, Rowan, Pemberton, Helen N, Postel-Vinay, Sophie, Rafiq, Rumana, Selfe, Joanna L, von Kriegsheim, Alex, Munoz, Amaya Garcia, Rodriguez, Javier, Shipley, Janet, van der Graaf, Winette T A, Williamson, Chris T, Ryan, Colm J, Pettitt, Stephen, Ashworth, Alan, Strauss, Sandra J, Lord, Christopher J
Published in Scientific reports (13.07.2018)
Published in Scientific reports (13.07.2018)
Get full text
Journal Article
Author Correction: Chemosensitivity profiling of osteosarcoma tumour cell lines identifies a model of BRCAness
Holme, Harriett, Gulati, Aditi, Brough, Rachel, Fleuren, Emmy D G, Bajrami, Ilirjana, Campbell, James, Chong, Irene Y, Costa-Cabral, Sara, Elliott, Richard, Fenton, Tim, Frankum, Jessica, Jones, Samuel E, Menon, Malini, Miller, Rowan, Pemberton, Helen N, Postel-Vinay, Sophie, Rafiq, Rumana, Selfe, Joanna L, von Kriegsheim, Alex, Munoz, Amaya Garcia, Rodriguez, Javier, Shipley, Janet, van der Graaf, Winette T A, Williamson, Chris T, Ryan, Colm J, Pettitt, Stephen, Ashworth, Alan, Strauss, Sandra J, Lord, Christopher J
Published in Scientific reports (21.08.2018)
Published in Scientific reports (21.08.2018)
Get full text
Journal Article
Genomic Classification and Clinical Outcome in Rhabdomyosarcoma: A Report From an International Consortium
Shern, Jack F, Selfe, Joanna, Izquierdo, Elisa, Patidar, Rajesh, Chou, Hsien-Chao, Song, Young K, Yohe, Marielle E, Sindiri, Sivasish, Wei, Jun, Wen, Xinyu, Rudzinski, Erin R, Barkauskas, Donald A, Lo, Tammy, Hall, David, Linardic, Corinne M, Hughes, Debbie, Jamal, Sabri, Jenney, Meriel, Chisholm, Julia, Brown, Rebecca, Jones, Kristine, Hicks, Belynda, Angelini, Paola, George, Sally, Chesler, Louis, Hubank, Michael, Kelsey, Anna, Gatz, Susanne A, Skapek, Stephen X, Hawkins, Douglas S, Shipley, Janet M, Khan, Javed
Published in Journal of clinical oncology (10.09.2021)
Published in Journal of clinical oncology (10.09.2021)
Get full text
Journal Article
Endo180 (MRC2) Antibody-Drug Conjugate for the Treatment of Sarcoma
Evans, Rachel J, Perkins, Douglas W, Selfe, Joanna, Kelsey, Anna, Birch, Gavin P, Shipley, Janet M, Schipper, Koen, Isacke, Clare M
Published in Molecular cancer therapeutics (01.02.2023)
Published in Molecular cancer therapeutics (01.02.2023)
Get full text
Journal Article
The Hippo effector TAZ (WWTR1) transforms myoblasts and TAZ abundance is associated with reduced survival in embryonal rhabdomyosarcoma
Mohamed, Abdalla, Sun, Congshan, De Mello, Vanessa, Selfe, Joanna, Missiaglia, Edoardo, Shipley, Janet, Murray, Graeme I, Zammit, Pete S, Wackerhage, Henning
Published in The Journal of pathology (01.09.2016)
Published in The Journal of pathology (01.09.2016)
Get full text
Journal Article