Preclinical Development of Ipilimumab and Nivolumab Combination Immunotherapy: Mouse Tumor Models, In Vitro Functional Studies, and Cynomolgus Macaque Toxicology
Selby, Mark J, Engelhardt, John J, Johnston, Robert J, Lu, Li-Sheng, Han, Minhua, Thudium, Kent, Yao, Dapeng, Quigley, Michael, Valle, Jose, Wang, Changyu, Chen, Bing, Cardarelli, Pina M, Blanset, Diann, Korman, Alan J
Published in PloS one (09.09.2016)
Published in PloS one (09.09.2016)
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Elective Nodal Irradiation Attenuates the Combinatorial Efficacy of Stereotactic Radiation Therapy and Immunotherapy
Marciscano, Ariel E, Ghasemzadeh, Ali, Nirschl, Thomas R, Theodros, Debebe, Kochel, Christina M, Francica, Brian J, Muroyama, Yuki, Anders, Robert A, Sharabi, Andrew B, Velarde, Esteban, Mao, Wendy, Chaudhary, Kunal R, Chaimowitz, Matthew G, Wong, John, Selby, Mark J, Thudium, Kent B, Korman, Alan J, Ulmert, David, Thorek, Daniel L J, DeWeese, Theodore L, Drake, Charles G
Published in Clinical cancer research (15.10.2018)
Published in Clinical cancer research (15.10.2018)
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Temporally Distinct PD-L1 Expression by Tumor and Host Cells Contributes to Immune Escape
Noguchi, Takuro, Ward, Jeffrey P, Gubin, Matthew M, Arthur, Cora D, Lee, Sang Hun, Hundal, Jasreet, Selby, Mark J, Graziano, Robert F, Mardis, Elaine R, Korman, Alan J, Schreiber, Robert D
Published in Cancer immunology research (01.02.2017)
Published in Cancer immunology research (01.02.2017)
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Interleukin-21 combined with PD-1 or CTLA-4 blockade enhances antitumor immunity in mouse tumor models
Lewis, Katherine E., Selby, Mark J., Masters, Gregg, Valle, Jose, Dito, Gennaro, Curtis, Wendy R., Garcia, Richard, Mink, Kathy A., Waggie, Kimberly S., Holdren, Matthew S., Grosso, Joseph F., Korman, Alan J., Jure-Kunkel, Maria, Dillon, Stacey R.
Published in Oncoimmunology (02.01.2018)
Published in Oncoimmunology (02.01.2018)
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Increased DNA Vaccine Delivery and Immunogenicity by Electroporation In Vivo
Widera, Georg, Austin, Melissa, Rabussay, Dietmar, Goldbeck, Cheryl, Barnett, Susan W, Chen, Minchao, Leung, Louisa, Otten, Gillis R, Thudium, Kent, Selby, Mark J, Ulmer, Jeffrey B
Published in The Journal of immunology (1950) (01.05.2000)
Published in The Journal of immunology (1950) (01.05.2000)
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Journal Article
Correction: Preclinical Development of Ipilimumab and Nivolumab Combination Immunotherapy: Mouse Tumor Models, In Vitro Functional Studies, and Cynomolgus Macaque Toxicology
Selby, Mark J, Engelhardt, John J, Johnston, Robert J, Lu, Li-Sheng, Han, Minhua, Thudium, Kent, Yao, Dapeng, Quigley, Michael, Valle, Jose, Wang, Changyu, Chen, Bing, Cardarelli, Pina M, Blanset, Diann, Korman, Alan J
Published in PloS one (18.11.2016)
Published in PloS one (18.11.2016)
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Journal Article
Anti-CTLA-4 antibodies of IgG2a isotype enhance antitumor activity through reduction of intratumoral regulatory T cells
Selby, Mark J, Engelhardt, John J, Quigley, Michael, Henning, Karla A, Chen, Timothy, Srinivasan, Mohan, Korman, Alan J
Published in Cancer immunology research (01.07.2013)
Published in Cancer immunology research (01.07.2013)
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In vitro characterization of the anti-PD-1 antibody nivolumab, BMS-936558, and in vivo toxicology in non-human primates
Wang, Changyu, Thudium, Kent B, Han, Minhua, Wang, Xi-Tao, Huang, Haichun, Feingersh, Diane, Garcia, Candy, Wu, Yi, Kuhne, Michelle, Srinivasan, Mohan, Singh, Sujata, Wong, Susan, Garner, Neysa, Leblanc, Heidi, Bunch, R Todd, Blanset, Diann, Selby, Mark J, Korman, Alan J
Published in Cancer immunology research (01.09.2014)
Published in Cancer immunology research (01.09.2014)
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A conserved intratumoral regulatory T cell signature identifies 4-1BB as a pan-cancer target
Freeman, Zachary T, Nirschl, Thomas R, Hovelson, Daniel H, Johnston, Robert J, Engelhardt, John J, Selby, Mark J, Kochel, Christina M, Lan, Ruth Y, Zhai, Jingyi, Ghasemzadeh, Ali, Gupta, Anuj, Skaist, Alyza M, Wheelan, Sarah J, Jiang, Hui, Pearson, Alexander T, Snyder, Linda A, Korman, Alan J, Tomlins, Scott A, Yegnasubramanian, Srinivasan, Drake, Charles G
Published in The Journal of clinical investigation (01.03.2020)
Published in The Journal of clinical investigation (01.03.2020)
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Castration-mediated IL-8 promotes myeloid infiltration and prostate cancer progression
Lopez-Bujanda, Zoila A, Haffner, Michael C, Chaimowitz, Matthew G, Chowdhury, Nivedita, Venturini, Nicholas J, Patel, Radhika A, Obradovic, Aleksandar, Hansen, Corey S, Jacków, Joanna, Maynard, Janielle P, Sfanos, Karen S, Abate-Shen, Cory, Bieberich, Charles J, Hurley, Paula J, Selby, Mark J, Korman, Alan J, Christiano, Angela M, De Marzo, Angelo M, Drake, Charles G
Published in Nature cancer (01.08.2021)
Published in Nature cancer (01.08.2021)
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Combining intratumoral Treg depletion with androgen deprivation therapy (ADT): preclinical activity in the Myc-CaP model
Shen, Ying-Chun, Ghasemzadeh, Ali, Kochel, Christina M, Nirschl, Thomas R, Francica, Brian J, Lopez-Bujanda, Zoila A, Carrera Haro, Maria A, Tam, Ada, Anders, Robert A, Selby, Mark J, Korman, Alan J, Drake, Charles G
Published in Prostate cancer and prostatic diseases (01.04.2018)
Published in Prostate cancer and prostatic diseases (01.04.2018)
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Journal Article
Aryl hydrocarbon receptor acts as a tumor suppressor in a syngeneic MC38 colon carcinoma tumor model
Yakkundi, Poonam, Gonsalves, Eleanor, Galou-Lameyer, Maria, Selby, Mark J, Chan, William K
Published in Hypoxia (01.01.2019)
Published in Hypoxia (01.01.2019)
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Journal Article
Synthesis of a novel hepatitis C virus protein by ribosomal frameshift
Xu, Zhenming, Choi, Jinah, Yen, T.S.Benedict, Lu, Wen, Strohecker, Anne, Govindarajan, Sugantha, Chien, David, Selby, Mark J., Ou, Jing-hsiung
Published in The EMBO journal (16.07.2001)
Published in The EMBO journal (16.07.2001)
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Journal Article
Distribution of DNA Vaccines Determines Their Immunogenicity After Intramuscular Injection in Mice
Dupuis, Marc, Denis-Mize, Kimberly, Woo, Carolyn, Goldbeck, Cheryl, Selby, Mark J, Chen, Minchao, Otten, Gillis R, Ulmer, Jeffrey B, Donnelly, John J, Ott, Gary, McDonald, Donald M
Published in The Journal of immunology (1950) (01.09.2000)
Published in The Journal of immunology (1950) (01.09.2000)
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Journal Article
LAG-3 -PD-1 COMBINATION OF ANTI-LAG-3 ANTIBODIES AND ANTI-PD-1 ANTIBODIES TO TREAT TUMORS
SELBY MARK J, LONBERG NILS, LEWIS KATHERINE E, KORMAN ALAN J, GUTIERREZ ANDRES A, FONTANA DAVID J
Year of Publication 12.03.2024
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Year of Publication 12.03.2024
Patent
HUMAN MONOCLONAL ANTIBODY AGAINST PROGRAMMED DEATH 1 (PD-1) AND METHOD FOR TREATING CANCER USING ANTI-PD-1 ANTIBODY ALONE OR IN COMBINATION WITH OTHER IMMUNOTHERAPY
SELBY MARK J, WANG CHANGYU, CHEN BING, KORMAN ALAN J, HUANG HAICHUN, CARDARELLI JOSEPHINE M, SRINIVASAN MOHAN
Year of Publication 21.02.2024
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Year of Publication 21.02.2024
Patent
LAG-3 -PD-1 COMBINATION OF ANTI-LAG-3 ANTIBODIES AND ANTI-PD-1 ANTIBODIES TO TREAT TUMORS
SELBY MARK J, LONBERG NILS, LEWIS KATHERINE E, KORMAN ALAN J, GUTIERREZ ANDRES A, FONTANA DAVID J
Year of Publication 13.01.2023
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Year of Publication 13.01.2023
Patent