Getting a Handle on Neuropharmacology by Targeting Receptor-Associated Proteins
Maher, Michael P., Matta, Jose A., Gu, Shenyan, Seierstad, Mark, Bredt, David S.
Published in Neuron (Cambridge, Mass.) (06.12.2017)
Published in Neuron (Cambridge, Mass.) (06.12.2017)
Get full text
Journal Article
Dual serotonin transporter/histamine H3 ligands : Optimization of the H3 pharmacophore
KEITH, John M, GOMEZ, Leslie A, MAZUR, Curt, LOVENBERG, Timothy W, CARRUTHERS, Nicholas I, LETAVIC, Michael A, LY, Kiev S, JABLONOWSKI, Jill A, SEIERSTAD, Mark, BARBIER, Ann J, WILSON, Sandy J, BOGGS, Jamin D, FRASER, Ian C
Published in Bioorganic & medicinal chemistry letters (01.02.2007)
Published in Bioorganic & medicinal chemistry letters (01.02.2007)
Get full text
Journal Article
R3(BΔ23–27)R/I5 Chimeric Peptide, a Selective Antagonist for GPCR135 and GPCR142 over Relaxin Receptor LGR7
Kuei, Chester, Sutton, Steven, Bonaventure, Pascal, Pudiak, Cindy, Shelton, Jonathan, Zhu, Jessica, Nepomuceno, Diane, Wu, Jiejun, Chen, Jingcai, Kamme, Fredrik, Seierstad, Mark, Hack, Michael D., Bathgate, Ross A.D., Hossain, Mohammed Akhter, Wade, John D., Atack, John, Lovenberg, Timothy W., Liu, Changlu
Published in The Journal of biological chemistry (31.08.2007)
Published in The Journal of biological chemistry (31.08.2007)
Get full text
Journal Article
Correction: Convergent synthesis of thiodiazole dioxides from simple ketones and amines through an unusual nitrogen-migration mechanism
Punjajom, Kunlayanee, Sinclair, Paul P, Saha, Ishika, Seierstad, Mark, Ameriks, Michael K, García-Reynaga, Pablo, Lebold, Terry P, Sarpong, Richmond
Published in Chemical science (Cambridge) (17.07.2024)
Published in Chemical science (Cambridge) (17.07.2024)
Get full text
Journal Article
Convergent synthesis of thiodiazole dioxides from simple ketones and amines through an unusual nitrogen-migration mechanism
Punjajom, Kunlayanee, Sinclair, Paul P, Saha, Ishika, Seierstad, Mark, Ameriks, Michael K, García-Reynaga, Pablo, Lebold, Terry P, Sarpong, Richmond
Published in Chemical science (Cambridge) (20.12.2023)
Published in Chemical science (Cambridge) (20.12.2023)
Get full text
Journal Article
Identification of highly selective SIK1/2 inhibitors that modulate innate immune activation and suppress intestinal inflammation
Babbe, Holger, Sundberg, Thomas B, Tichenor, Mark, Seierstad, Mark, Bacani, Genesis, Berstler, James, Chai, Wenying, Chang, Leon, Chung, De Michael, Coe, Kevin, Collins, Bernard, Finley, Michael, Guletsky, Alexander, Lemke, Christopher T, Mak, Puiying A, Mathur, Ashok, Mercado-Marin, Eduardo V, Metkar, Shailesh, Raymond, Donald D, Rives, Marie-Laure, Rizzolio, Michele, Shaffer, Paul L, Smith, Russell, Smith, Jacqueline, Steele, Ruth, Steffens, Helena, Suarez, Javier, Tian, Gaochao, Majewski, Nathan, Volak, Laurie P, Wei, Jianmei, Desai, Prerak T, Ong, Luvena L, Koudriakova, Tatiana, Goldberg, Steven D, Hirst, Gavin, Kaushik, Virendar K, Ort, Tatiana, Seth, Nilufer, Graham, Daniel B, Plevy, Scott, Venable, Jennifer D, Xavier, Ramnik J, Towne, Jennifer E
Published in Proceedings of the National Academy of Sciences - PNAS (02.01.2024)
Published in Proceedings of the National Academy of Sciences - PNAS (02.01.2024)
Get full text
Journal Article
Discovery of a Gut-Restricted JAK Inhibitor for the Treatment of Inflammatory Bowel Disease
Leonard, Kristi A, Madge, Lisa A, Krawczuk, Paul J, Wang, Aihua, Kreutter, Kevin D, Bacani, Genesis M, Chai, Wenying, Smith, Russell C, Tichenor, Mark S, Harris, Michael C, Malaviya, Ravi, Seierstad, Mark, Johnson, Marguerite E, Venable, Jennifer D, Kim, Suzie, Hirst, Gavin C, Mathur, Ashok S, Rao, Tadimeti S, Edwards, James P, Rizzolio, Michele C, Koudriakova, Tatiana
Published in Journal of medicinal chemistry (26.03.2020)
Published in Journal of medicinal chemistry (26.03.2020)
Get full text
Journal Article
Discovery of JNJ-64264681: A Potent and Selective Covalent Inhibitor of Bruton’s Tyrosine Kinase
Tichenor, Mark S., Wiener, John J. M., Rao, Navin L., Bacani, Genesis M., Wei, Jianmei, Pooley Deckhut, Charlotte, Barbay, J. Kent, Kreutter, Kevin D., Chang, Leon, Clancy, Kathleen W., Murrey, Heather E., Wang, Weixue, Ahn, Kay, Huber, Michael, Rex, Elizabeth, Coe, Kevin J., Wu, Jiejun, Rui, Haopeng, Sepassi, Kia, Gaudiano, Marcello, Bekkers, Mariette, Cornelissen, Ivo, Packman, Kathryn, Seierstad, Mark, Xiouras, Christos, Bembenek, Scott D., Alexander, Richard, Milligan, Cynthia, Balasubramanian, Sriram, Lebsack, Alec D., Venable, Jennifer D., Philippar, Ulrike, Edwards, James P., Hirst, Gavin
Published in Journal of medicinal chemistry (10.11.2022)
Published in Journal of medicinal chemistry (10.11.2022)
Get full text
Journal Article
Structure-Based Optimization of Selective and Brain Penetrant CK1δ Inhibitors for the Treatment of Circadian Disruptions
McCarver, Stefan, Hanna, Luke, Samant, Andrew, Thompson, Aaron A., Seierstad, Mark, Saha, Arjun, Wu, Dongpei, Lord, Brian, Sutton, Steven W., Shah, Vishal, Milligan, Cynthia M., Wennerholm, Michelle, Shelton, Jonathan, Lebold, Terry P., Shireman, Brock T.
Published in ACS medicinal chemistry letters (11.04.2024)
Published in ACS medicinal chemistry letters (11.04.2024)
Get full text
Journal Article
Heteroarylureas with fused bicyclic diamine cores as inhibitors of fatty acid amide hydrolase
Keith, John M., Jones, William, Pierce, Joan M., Seierstad, Mark, Palmer, James A., Webb, Michael, Karbarz, Mark, Scott, Brian P., Wilson, Sandy J., Luo, Lin, Wennerholm, Michelle, Chang, Leon, Rizzolio, Michele, Rynberg, Raymond, Chaplan, Sandra, Guy Breitenbucher, J.
Published in Bioorganic & medicinal chemistry letters (15.10.2020)
Published in Bioorganic & medicinal chemistry letters (15.10.2020)
Get full text
Journal Article
Novel Reagent Space: Identifying Unorderable but Readily Synthesizable Building Blocks
Seierstad, Mark, Tichenor, Mark S, DesJarlais, Renee L, Na, Jim, Bacani, Genesis M, Chung, De Michael, Mercado-Marin, Eduardo V, Steffens, Helena C, Mirzadegan, Taraneh
Published in ACS medicinal chemistry letters (11.11.2021)
Published in ACS medicinal chemistry letters (11.11.2021)
Get full text
Journal Article
Preclinical Characterization of the FAAH Inhibitor JNJ-42165279
Keith, John M, Jones, William M, Tichenor, Mark, Liu, Jing, Seierstad, Mark, Palmer, James A, Webb, Michael, Karbarz, Mark, Scott, Brian P, Wilson, Sandy J, Luo, Lin, Wennerholm, Michelle L, Chang, Leon, Rizzolio, Michele, Rynberg, Raymond, Chaplan, Sandra R, Breitenbucher, J. Guy
Published in ACS medicinal chemistry letters (10.12.2015)
Published in ACS medicinal chemistry letters (10.12.2015)
Get full text
Journal Article
R3(BDelta23 27)R/I5 chimeric peptide, a selective antagonist for GPCR135 and GPCR142 over relaxin receptor LGR7: in vitro and in vivo characterization
Kuei, Chester, Sutton, Steven, Bonaventure, Pascal, Pudiak, Cindy, Shelton, Jonathan, Zhu, Jessica, Nepomuceno, Diane, Wu, Jiejun, Chen, Jingcai, Kamme, Fredrik, Seierstad, Mark, Hack, Michael D, Bathgate, Ross A D, Hossain, Mohammed Akhter, Wade, John D, Atack, John, Lovenberg, Timothy W, Liu, Changlu
Published in The Journal of biological chemistry (31.08.2007)
Published in The Journal of biological chemistry (31.08.2007)
Get full text
Journal Article
카제인 키나아제 1 델타 조절제
PATRICK KELSEY, HANNA LUKE EDWARD, SEIERSTAD MARK, SWIFT ELIZABETH, SAMANT ANDREW V, WU DONGPEI, MCCARVER STEFAN, LEBOLD TERRY PATRICK, PREVILLE CATHY, SHIREMAN BROCK T
Year of Publication 19.05.2023
Get full text
Year of Publication 19.05.2023
Patent
카제인 키나제 1 델타 조절제
MCCLURE KELLY J, WANG JOCELYN, SEIERSTAD MARK, ZIFF JEANNIE, WU DONGPEI, MCCARVER STEFAN, ZHANG WEI, LEBOLD TERRY PATRICK, PREVILLE CATHY, SHIREMAN BROCK T
Year of Publication 18.05.2023
Get full text
Year of Publication 18.05.2023
Patent
Discovery of Imidazo[1,2‑a]pyrazines and Pyrazolo[1,5‑c]pyrimidines as TARP γ‑8 Selective AMPAR Negative Modulators
Savall, Brad M, Wu, Dongpei, Swanson, Devin M, Seierstad, Mark, Wu, Nyantsz, Vives Martinez, Jorge, García Olmos, Beatriz, Lord, Brian, Coe, Kevin, Koudriakova, Tatiana, Lovenberg, Timothy W, Carruthers, Nicholas I, Maher, Michael P, Ameriks, Michael K
Published in ACS medicinal chemistry letters (14.03.2019)
Published in ACS medicinal chemistry letters (14.03.2019)
Get full text
Journal Article