Fragment-Based Discovery of New Highly Substituted 1H‑Pyrrolo[2,3‑b]- and 3H‑Imidazolo[4,5‑b]‑Pyridines as Focal Adhesion Kinase Inhibitors
Heinrich, Timo, Seenisamy, Jeyaprakashnarayanan, Emmanuvel, Lourdusamy, Kulkarni, Santosh S, Bomke, Jörg, Rohdich, Felix, Greiner, Hartmut, Esdar, Christina, Krier, Mireille, Grädler, Ulrich, Musil, Djordje
Published in Journal of medicinal chemistry (14.02.2013)
Published in Journal of medicinal chemistry (14.02.2013)
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Journal Article
Telomestatin and Diseleno Sapphyrin Bind Selectively to Two Different Forms of the Human Telomeric G-Quadruplex Structure
Rezler, Evonne M, Seenisamy, Jeyaprakashnarayanan, Bashyam, Sridevi, Kim, Mu-Yong, White, Elizabeth, Wilson, W. David, Hurley, Laurence H
Published in Journal of the American Chemical Society (06.07.2005)
Published in Journal of the American Chemical Society (06.07.2005)
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Journal Article
The Dynamic Character of the G-Quadruplex Element in the c-MYC Promoter and Modification by TMPyP4
Seenisamy, Jeyaprakashnarayanan, Rezler, Evonne M, Powell, Tiffanie J, Tye, Denise, Gokhale, Vijay, Joshi, Chandana Sharma, Siddiqui-Jain, Adam, Hurley, Laurence H
Published in Journal of the American Chemical Society (21.07.2004)
Published in Journal of the American Chemical Society (21.07.2004)
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Discovery of Potent, Selective, and Orally Bioavailable Alkynylphenoxyacetic Acid CRTH2 (DP2) Receptor Antagonists for the Treatment of Allergic Inflammatory Diseases
Crosignani, Stefano, Prêtre, Adeline, Jorand-Lebrun, Catherine, Fraboulet, Gaële, Seenisamy, Jeyaprakashnarayanan, Augustine, John Kallikat, Missotten, Marc, Humbert, Yves, Cleva, Christophe, Abla, Nada, Daff, Hamina, Schott, Olivier, Schneider, Manfred, Burgat-Charvillon, Fabienne, Rivron, Delphine, Hamernig, Ingrid, Arrighi, Jean-François, Gaudet, Marilène, Zimmerli, Simone C, Juillard, Pierre, Johnson, Zoe
Published in Journal of medicinal chemistry (27.10.2011)
Published in Journal of medicinal chemistry (27.10.2011)
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Journal Article
Solvent-Dependent Photophysics and Reactivity of Monomeric and Dimeric 4‑Amino-1,8-Naphthalimides
Kelly, Lisa A, Roll, Melissa, Joseph, Jayan, Seenisamy, Jeyaprakashnarayanan, Barrett, Justin, Kauser, Katalin, Warner, Kevin S
Published in The journal of physical chemistry. A, Molecules, spectroscopy, kinetics, environment, & general theory (25.03.2021)
Published in The journal of physical chemistry. A, Molecules, spectroscopy, kinetics, environment, & general theory (25.03.2021)
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Journal Article
Discovery and Structure-Based Optimization of Next-Generation Reversible Methionine Aminopeptidase‑2 (MetAP-2) Inhibitors
Heinrich, Timo, Seenisamy, Jeyaprakashnarayanan, Blume, Beatrix, Bomke, Jörg, Calderini, Michel, Eckert, Uwe, Friese-Hamim, Manja, Kohl, Rainer, Lehmann, Martin, Leuthner, Birgitta, Musil, Djordje, Rohdich, Felix, Zenke, Frank T
Published in Journal of medicinal chemistry (23.05.2019)
Published in Journal of medicinal chemistry (23.05.2019)
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Journal Article
Identification of Methionine Aminopeptidase‑2 (MetAP-2) Inhibitor M8891: A Clinical Compound for the Treatment of Cancer
Heinrich, Timo, Seenisamy, Jeyaprakashnarayanan, Becker, Frank, Blume, Beatrix, Bomke, Jörg, Dietz, Melanie, Eckert, Uwe, Friese-Hamim, Manja, Gunera, Jakub, Hansen, Kerrin, Leuthner, Birgitta, Musil, Djordje, Pfalzgraf, Jens, Rohdich, Felix, Siegl, Christian, Spuck, Dieter, Wegener, Ansgar, Zenke, Frank T
Published in Journal of medicinal chemistry (26.12.2019)
Published in Journal of medicinal chemistry (26.12.2019)
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Structure-Based Optimization and Discovery of M3258, a Specific Inhibitor of the Immunoproteasome Subunit LMP7 (β5i)
Klein, Markus, Busch, Michael, Friese-Hamim, Manja, Crosignani, Stefano, Fuchss, Thomas, Musil, Djordje, Rohdich, Felix, Sanderson, Michael P, Seenisamy, Jeyaprakashnarayanan, Walter-Bausch, Gina, Zanelli, Ugo, Hewitt, Philip, Esdar, Christina, Schadt, Oliver
Published in Journal of medicinal chemistry (22.07.2021)
Published in Journal of medicinal chemistry (22.07.2021)
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Synthesis and SAR development of quinoline analogs as novel P2X7 receptor antagonists
Xiao, Yufang, Karra, Srinivasa, Goutopoulos, Andreas, Morse, Noune Tahmassian, Zhang, Susan, Dhanabal, Mohanraj, Tian, Hui, Seenisamy, Jeyaprakashnarayanan, Jayadevan, Jayashankaran, Caldwell, Richard, Potnick, Justin, Bleich, Matthew, Chekler, Eugene, Sherer, Brian, Sriraman, Venkataraman
Published in Bioorganic & medicinal chemistry letters (01.07.2019)
Published in Bioorganic & medicinal chemistry letters (01.07.2019)
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Journal Article
Design and Synthesis of an Expanded Porphyrin That Has Selectivity for the c-MYC G-Quadruplex Structure
Seenisamy, Jeyaprakashnarayanan, Bashyam, Sridevi, Gokhale, Vijay, Vankayalapati, Hariprasad, Sun, Daekyu, Siddiqui-Jain, Adam, Streiner, Nicole, Shin-ya, Kazuo, White, Elizabeth, Wilson, W. David, Hurley, Laurence H
Published in Journal of the American Chemical Society (09.03.2005)
Published in Journal of the American Chemical Society (09.03.2005)
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Journal Article
티로신 키나제 비-수용체 1 (TNK1) 억제제 및 그의 용도
WARNER STEVEN L, SIDDIQUI JAIN ADAM, WHATCOTT CLIFFORD J, SEENISAMY JEYAPRAKASHNARAYANAN, BEARSS DAVID J
Year of Publication 08.03.2022
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Year of Publication 08.03.2022
Patent
Fragment-Based Discovery of New Highly Substituted 1 H -Pyrrolo[2,3- b ]- and 3 H -Imidazolo[4,5- b ]-Pyridines as Focal Adhesion Kinase Inhibitors
Heinrich, Timo, Seenisamy, Jeyaprakashnarayanan, Emmanuvel, Lourdusamy, Kulkarni, Santosh S., Bomke, Jörg, Rohdich, Felix, Greiner, Hartmut, Esdar, Christina, Krier, Mireille, Grädler, Ulrich, Musil, Djordje
Published in Journal of medicinal chemistry (14.02.2013)
Published in Journal of medicinal chemistry (14.02.2013)
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Journal Article