LINE1 Derepression in Aged Wild-Type and SIRT6-Deficient Mice Drives Inflammation
Simon, Matthew, Van Meter, Michael, Ablaeva, Julia, Ke, Zhonghe, Gonzalez, Raul S., Taguchi, Taketo, De Cecco, Marco, Leonova, Katerina I., Kogan, Valeria, Helfand, Stephen L., Neretti, Nicola, Roichman, Asael, Cohen, Haim Y., Meer, Margarita V., Gladyshev, Vadim N., Antoch, Marina P., Gudkov, Andrei V., Sedivy, John M., Seluanov, Andrei, Gorbunova, Vera
Published in Cell metabolism (02.04.2019)
Published in Cell metabolism (02.04.2019)
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Journal Article
Transcriptional landscape of repetitive elements in normal and cancer human cells
Criscione, Steven W, Zhang, Yue, Thompson, William, Sedivy, John M, Neretti, Nicola
Published in BMC genomics (11.07.2014)
Published in BMC genomics (11.07.2014)
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Journal Article
Inflammation, epigenetics, and metabolism converge to cell senescence and ageing: the regulation and intervention
Zhu, Xudong, Chen, Zhiyang, Shen, Weiyan, Huang, Gang, Sedivy, John M, Wang, Hu, Ju, Zhenyu
Published in Signal transduction and targeted therapy (28.06.2021)
Published in Signal transduction and targeted therapy (28.06.2021)
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Journal Article
Reduced Expression of MYC Increases Longevity and Enhances Healthspan
Hofmann, Jeffrey W., Zhao, Xiaoai, De Cecco, Marco, Peterson, Abigail L., Pagliaroli, Luca, Manivannan, Jayameenakshi, Hubbard, Gene B., Ikeno, Yuji, Zhang, Yongqing, Feng, Bin, Li, Xiaxi, Serre, Thomas, Qi, Wenbo, Van Remmen, Holly, Miller, Richard A., Bath, Kevin G., de Cabo, Rafael, Xu, Haiyan, Neretti, Nicola, Sedivy, John M.
Published in Cell (29.01.2015)
Published in Cell (29.01.2015)
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Journal Article
Identification and characterization of small molecule inhibitors of the LINE-1 retrotransposon endonuclease
D'Ordine, Alexandra M, Jogl, Gerwald, Sedivy, John M
Published in Nature communications (08.05.2024)
Published in Nature communications (08.05.2024)
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Journal Article
SLC1A5 glutamine transporter is a target of MYC and mediates reduced mTORC1 signaling and increased fatty acid oxidation in long‐lived Myc hypomorphic mice
Zhao, Xiaoai, Petrashen, Anna P., Sanders, Jennifer A., Peterson, Abigail L., Sedivy, John M.
Published in Aging cell (01.06.2019)
Published in Aging cell (01.06.2019)
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Journal Article
Genomes of replicatively senescent cells undergo global epigenetic changes leading to gene silencing and activation of transposable elements
Cecco, Marco, Criscione, Steven W., Peckham, Edward J., Hillenmeyer, Sara, Hamm, Eliza A., Manivannan, Jayameenakshi, Peterson, Abigail L., Kreiling, Jill A., Neretti, Nicola, Sedivy, John M.
Published in Aging cell (01.04.2013)
Published in Aging cell (01.04.2013)
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Journal Article
Cellular Senescence in Aging Primates
Herbig, Utz, Ferreira, Mark, Condel, Laura, Carey, Dee, Sedivy, John M
Published in Science (American Association for the Advancement of Science) (03.03.2006)
Published in Science (American Association for the Advancement of Science) (03.03.2006)
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Journal Article
Accumulation of senescent cells in mitotic tissue of aging primates
Jeyapalan, Jessie C., Ferreira, Mark, Sedivy, John M., Herbig, Utz
Published in Mechanisms of ageing and development (01.01.2007)
Published in Mechanisms of ageing and development (01.01.2007)
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Journal Article
Conference Proceeding
DNA Hypomethylation and Histone Variant macroH2A1 Synergistically Attenuate Chemotherapy-Induced Senescence to Promote Hepatocellular Carcinoma Progression
Borghesan, Michela, Fusilli, Caterina, Rappa, Francesca, Panebianco, Concetta, Rizzo, Giovanni, Oben, Jude A, Mazzoccoli, Gianluigi, Faulkes, Chris, Pata, Illar, Agodi, Antonella, Rezaee, Farhad, Minogue, Shane, Warren, Alessandra, Peterson, Abigail, Sedivy, John M, Douet, Julien, Buschbeck, Marcus, Cappello, Francesco, Mazza, Tommaso, Pazienza, Valerio, Vinciguerra, Manlio
Published in Cancer research (Chicago, Ill.) (01.02.2016)
Published in Cancer research (Chicago, Ill.) (01.02.2016)
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Journal Article
The number of p16INK4a positive cells in human skin reflects biological age
Waaijer, Mariëtte E.C., Parish, William E., Strongitharm, Barbara H., van Heemst, Diana, Slagboom, Pieternella E., de Craen, Anton J.M., Sedivy, John M., Westendorp, Rudi G.J., Gunn, David A., Maier, Andrea B.
Published in Aging cell (01.08.2012)
Published in Aging cell (01.08.2012)
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Journal Article
Global regulation of nucleotide biosynthetic genes by c-Myc
Liu, Yen-Chun, Li, Feng, Handler, Jesse, Huang, Cheng Ran Lisa, Xiang, Yan, Neretti, Nicola, Sedivy, John M, Zeller, Karen I, Dang, Chi V
Published in PloS one (16.07.2008)
Published in PloS one (16.07.2008)
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Journal Article
Age‐associated increase in heterochromatic marks in murine and primate tissues
Kreiling, Jill A., Tamamori‐Adachi, Mimi, Sexton, Alec N., Jeyapalan, Jessie C., Munoz‐Najar, Ursula, Peterson, Abigail L., Manivannan, Jayameenakshi, Rogers, Elizabeth S., Pchelintsev, Nikolay A., Adams, Peter D., Sedivy, John M.
Published in Aging cell (01.04.2011)
Published in Aging cell (01.04.2011)
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Journal Article
Proteomic profiling of Myc-associated proteins
Agrawal, Pooja, Yu, Kebing, Salomon, Arthur R., Sedivy, John M.
Published in Cell cycle (Georgetown, Tex.) (15.12.2010)
Published in Cell cycle (Georgetown, Tex.) (15.12.2010)
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