Serum Neutralizing Activity Elicited by mRNA-1273 Vaccine
Wu, Kai, Werner, Anne P, Koch, Matthew, Choi, Angela, Narayanan, Elisabeth, Stewart-Jones, Guillaume B.E, Colpitts, Tonya, Bennett, Hamilton, Boyoglu-Barnum, Seyhan, Shi, Wei, Moliva, Juan I, Sullivan, Nancy J, Graham, Barney S, Carfi, Andrea, Corbett, Kizzmekia S, Seder, Robert A, Edwards, Darin K
Published in New England Journal of Medicine (15.04.2021)
Published in New England Journal of Medicine (15.04.2021)
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Prevention of tuberculosis in macaques after intravenous BCG immunization
Darrah, Patricia A., Zeppa, Joseph J., Maiello, Pauline, Hackney, Joshua A., Wadsworth, Marc H., Hughes, Travis K., Pokkali, Supriya, Swanson, Phillip A., Grant, Nicole L., Rodgers, Mark A., Kamath, Megha, Causgrove, Chelsea M., Laddy, Dominick J., Bonavia, Aurelio, Casimiro, Danilo, Lin, Philana Ling, Klein, Edwin, White, Alexander G., Scanga, Charles A., Shalek, Alex K., Roederer, Mario, Flynn, JoAnne L., Seder, Robert A.
Published in Nature (London) (02.01.2020)
Published in Nature (London) (02.01.2020)
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Albumin/vaccine nanocomplexes that assemble in vivo for combination cancer immunotherapy
Zhu, Guizhi, Lynn, Geoffrey M., Jacobson, Orit, Chen, Kai, Liu, Yi, Zhang, Huimin, Ma, Ying, Zhang, Fuwu, Tian, Rui, Ni, Qianqian, Cheng, Siyuan, Wang, Zhantong, Lu, Nan, Yung, Bryant C., Wang, Zhe, Lang, Lixin, Fu, Xiao, Jin, Albert, Weiss, Ido D., Vishwasrao, Harshad, Niu, Gang, Shroff, Hari, Klinman, Dennis M., Seder, Robert A., Chen, Xiaoyuan
Published in Nature communications (05.12.2017)
Published in Nature communications (05.12.2017)
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SARS-CoV-2 variant prediction and antiviral drug design are enabled by RBD in vitro evolution
Zahradník, Jiří, Marciano, Shir, Shemesh, Maya, Zoler, Eyal, Harari, Daniel, Chiaravalli, Jeanne, Meyer, Björn, Rudich, Yinon, Li, Chunlin, Marton, Ira, Dym, Orly, Elad, Nadav, Lewis, Mark G., Andersen, Hanne, Gagne, Matthew, Seder, Robert A., Douek, Daniel C., Schreiber, Gideon
Published in Nature microbiology (01.09.2021)
Published in Nature microbiology (01.09.2021)
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Antibody Feedback Limits the Expansion of B Cell Responses to Malaria Vaccination but Drives Diversification of the Humoral Response
McNamara, Hayley A., Idris, Azza H., Sutton, Henry J., Vistein, Rachel, Flynn, Barbara J., Cai, Yeping, Wiehe, Kevin, Lyke, Kirsten E., Chatterjee, Deepyan, KC, Natasha, Chakravarty, Sumana, Lee Sim, B. Kim, Hoffman, Stephen L., Bonsignori, Mattia, Seder, Robert A., Cockburn, Ian A.
Published in Cell host & microbe (07.10.2020)
Published in Cell host & microbe (07.10.2020)
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Atypical B cells are part of an alternative lineage of B cells that participates in responses to vaccination and infection in humans
Sutton, Henry J., Aye, Racheal, Idris, Azza H., Vistein, Rachel, Nduati, Eunice, Kai, Oscar, Mwacharo, Jedida, Li, Xi, Gao, Xin, Andrews, T. Daniel, Koutsakos, Marios, Nguyen, Thi H.O., Nekrasov, Maxim, Milburn, Peter, Eltahla, Auda, Berry, Andrea A., KC, Natasha, Chakravarty, Sumana, Sim, B. Kim Lee, Wheatley, Adam K., Kent, Stephen J., Hoffman, Stephen L., Lyke, Kirsten E., Bejon, Philip, Luciani, Fabio, Kedzierska, Katherine, Seder, Robert A., Ndungu, Francis M., Cockburn, Ian A.
Published in Cell reports (Cambridge) (09.02.2021)
Published in Cell reports (Cambridge) (09.02.2021)
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Vaccine priming is restricted to draining lymph nodes and controlled by adjuvant-mediated antigen uptake
Liang, Frank, Lindgren, Gustaf, Sandgren, Kerrie J, Thompson, Elizabeth A, Francica, Joseph R, Seubert, Anja, De Gregorio, Ennio, Barnett, Susan, O'Hagan, Derek T, Sullivan, Nancy J, Koup, Richard A, Seder, Robert A, Loré, Karin
Published in Science translational medicine (07.06.2017)
Published in Science translational medicine (07.06.2017)
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Protective effects of combining monoclonal antibodies and vaccines against the Plasmodium falciparum circumsporozoite protein
Wang, Lawrence T, Pereira, Lais S, Kiyuka, Patience K, Schön, Arne, Kisalu, Neville K, Vistein, Rachel, Dillon, Marlon, Bonilla, Brian G, Molina-Cruz, Alvaro, Barillas-Mury, Carolina, Tan, Joshua, Idris, Azza H, Francica, Joseph R, Seder, Robert A
Published in PLoS pathogens (01.12.2021)
Published in PLoS pathogens (01.12.2021)
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Pathogen-Specific T Cell Polyfunctionality Is a Correlate of T Cell Efficacy and Immune Protection
Boyd, Anders, Almeida, Jorge R, Darrah, Patricia A, Sauce, Delphine, Seder, Robert A, Appay, Victor, Gorochov, Guy, Larsen, Martin
Published in PloS one (05.06.2015)
Published in PloS one (05.06.2015)
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Structural basis for self-discrimination by neoantigen-specific TCRs
Finnigan, John P., Newman, Jenna H., Patskovsky, Yury, Patskovska, Larysa, Ishizuka, Andrew S., Lynn, Geoffrey M., Seder, Robert A., Krogsgaard, Michelle, Bhardwaj, Nina
Published in Nature communications (08.03.2024)
Published in Nature communications (08.03.2024)
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Safety, Immunogenicity, and Protective Efficacy against Controlled Human Malaria Infection of Plasmodium falciparum Sporozoite Vaccine in Tanzanian Adults
Jongo, Said A, Shekalaghe, Seif A, Church, L W Preston, Ruben, Adam J, Schindler, Tobias, Zenklusen, Isabelle, Rutishauser, Tobias, Rothen, Julian, Tumbo, Anneth, Mkindi, Catherine, Mpina, Maximillian, Mtoro, Ali T, Ishizuka, Andrew S, Kassim, Kamaka Ramadhani, Milando, Florence A, Qassim, Munira, Juma, Omar A, Mwakasungula, Solomon, Simon, Beatus, James, Eric R, Abebe, Yonas, Kc, Natasha, Chakravarty, Sumana, Saverino, Elizabeth, Bakari, Bakari M, Billingsley, Peter F, Seder, Robert A, Daubenberger, Claudia, Sim, B Kim Lee, Richie, Thomas L, Tanner, Marcel, Abdulla, Salim, Hoffman, Stephen L
Published in The American journal of tropical medicine and hygiene (01.01.2018)
Published in The American journal of tropical medicine and hygiene (01.01.2018)
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Safety, immunogenicity and efficacy of PfSPZ Vaccine against malaria in infants in western Kenya: a double-blind, randomized, placebo-controlled phase 2 trial
Oneko, Martina, Steinhardt, Laura C., Yego, Reuben, Wiegand, Ryan E., Swanson, Phillip A., KC, Natasha, Akach, Dorcas, Sang, Tony, Gutman, Julie R., Nzuu, Elizabeth L., Dungani, Allan, Kim Lee Sim, B., Oloo, Paul Ndaya, Otieno, Kephas, Bii, Dennis K., Billingsley, Peter F., James, Eric R., Kariuki, Simon, Samuels, Aaron M., Jongo, Said, Chebore, Winnie, Abdulla, Salim, Daubenberger, Claudia, Mpina, Maxmillian, Styers, David, Potter, Gail E., Abarbanell, Ginnie, Richie, Thomas L., Hoffman, Stephen L., Seder, Robert A.
Published in Nature medicine (01.09.2021)
Published in Nature medicine (01.09.2021)
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The P. falciparum CSP repeat region contains three distinct epitopes required for protection by antibodies in vivo
Flores-Garcia, Yevel, Wang, Lawrence T, Park, Minah, Asady, Beejan, Idris, Azza H, Kisalu, Neville K, Muñoz, Christian, Pereira, Lais S, Francica, Joseph R, Seder, Robert A, Zavala, Fidel
Published in PLoS pathogens (08.11.2021)
Published in PLoS pathogens (08.11.2021)
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Monocytes Acquire the Ability to Prime Tissue-Resident T Cells via IL-10-Mediated TGF-β Release
Thompson, Elizabeth A., Darrah, Patricia A., Foulds, Kathryn E., Hoffer, Elena, Caffrey-Carr, Alayna, Norenstedt, Sophie, Perbeck, Leif, Seder, Robert A., Kedl, Ross M., Loré, Karin
Published in Cell reports (Cambridge) (30.07.2019)
Published in Cell reports (Cambridge) (30.07.2019)
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Structural basis of epitope selectivity and potent protection from malaria by PfCSP antibody L9
Martin, Gregory M., Fernández-Quintero, Monica L., Lee, Wen-Hsin, Pholcharee, Tossapol, Eshun-Wilson, Lisa, Liedl, Klaus R., Pancera, Marie, Seder, Robert A., Wilson, Ian A., Ward, Andrew B.
Published in Nature communications (17.05.2023)
Published in Nature communications (17.05.2023)
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Star nanoparticles delivering HIV-1 peptide minimal immunogens elicit near-native envelope antibody responses in nonhuman primates
Francica, Joseph R, Laga, Richard, Lynn, Geoffrey M, Mužíková, Gabriela, Androvič, Ladislav, Aussedat, Baptiste, Walkowicz, William E, Padhan, Kartika, Ramirez-Valdez, Ramiro Andrei, Parks, Robert, Schmidt, Stephen D, Flynn, Barbara J, Tsybovsky, Yaroslav, Stewart-Jones, Guillaume B E, Saunders, Kevin O, Baharom, Faezzah, Petrovas, Constantinos, Haynes, Barton F, Seder, Robert A
Published in PLoS biology (17.06.2019)
Published in PLoS biology (17.06.2019)
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Interaction dynamics between innate and adaptive immune cells responding to SARS-CoV-2 vaccination in non-human primates
Schramm, Chaim A., Moon, Damee, Peyton, Lowrey, Lima, Noemia S., Wake, Christian, Boswell, Kristin L., Henry, Amy R., Laboune, Farida, Ambrozak, David, Darko, Samuel W., Teng, I-Ting, Foulds, Kathryn E., Carfi, Andrea, Edwards, Darin K., Kwong, Peter D., Koup, Richard A., Seder, Robert A., Douek, Daniel C.
Published in Nature communications (02.12.2023)
Published in Nature communications (02.12.2023)
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Intravenous heterologous prime-boost vaccination activates innate and adaptive immunity to promote tumor regression
Ramirez-Valdez, Ramiro A., Baharom, Faezzah, Khalilnezhad, Ahad, Fussell, Sloane C., Hermans, Dalton J., Schrager, Alexander M., Tobin, Kennedy K.S., Lynn, Geoffrey M., Khalilnezhad, Shabnam, Ginhoux, Florent, Van den Eynde, Benoit J., Leung, Carol Sze Ki, Ishizuka, Andrew S., Seder, Robert A.
Published in Cell reports (Cambridge) (27.06.2023)
Published in Cell reports (Cambridge) (27.06.2023)
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Mucosal vaccines for SARS-CoV-2: scientific gaps and opportunities—workshop report
Knisely, Jane M., Buyon, Lucas E., Mandt, Rebecca, Farkas, Rebecca, Balasingam, Shobana, Bok, Karin, Buchholz, Ursula J., D’Souza, M. Patricia, Gordon, Jennifer L., King, Deborah F. L., Le, Tung T., Leitner, Wolfgang W., Seder, Robert A., Togias, Alkis, Tollefsen, Stig, Vaughn, David W., Wolfe, Daniel N., Taylor, Kimberly L., Fauci, Anthony S.
Published in npj vaccines (12.04.2023)
Published in npj vaccines (12.04.2023)
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Variant-proof high affinity ACE2 antagonist limits SARS-CoV-2 replication in upper and lower airways
Gagne, Matthew, Flynn, Barbara J., Honeycutt, Christopher Cole, Flebbe, Dillon R., Andrew, Shayne F., Provost, Samantha J., McCormick, Lauren, Van Ry, Alex, McCarthy, Elizabeth, Todd, John-Paul M., Bao, Saran, Teng, I-Ting, Marciano, Shir, Rudich, Yinon, Li, Chunlin, Jain, Shilpi, Wali, Bushra, Pessaint, Laurent, Dodson, Alan, Cook, Anthony, Lewis, Mark G., Andersen, Hanne, Zahradník, Jiří, Suthar, Mehul S., Nason, Martha C., Foulds, Kathryn E., Kwong, Peter D., Roederer, Mario, Schreiber, Gideon, Seder, Robert A., Douek, Daniel C.
Published in Nature communications (12.08.2024)
Published in Nature communications (12.08.2024)
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