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Samraj, Annie N., Pearce, Oliver M. T., Läubli, Heinz, Crittenden, Alyssa N., Bergfeld, Anne K., Banda, Kalyan, Gregg, Christopher J., Bingman, Andrea E., Secrest, Patrick, Diaz, Sandra L., Varki, Nissi M., Varki, Ajit
Published in Proceedings of the National Academy of Sciences - PNAS (13.01.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (13.01.2015)
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Engagement of myelomonocytic Siglecs by tumor-associated ligands modulates the innate immune response to cancer
Läubli, Heinz, Pearce, Oliver M. T., Schwarz, Flavio, Siddiqui, Shoib S., Deng, Lingquan, Stanczak, Michal A., Deng, Liwen, Verhagen, Andrea, Secrest, Patrick, Lusk, Chrissy, Schwartz, Ann G., Varki, Nissi M., Bui, Jack D., Varki, Ajit
Published in Proceedings of the National Academy of Sciences - PNAS (30.09.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (30.09.2014)
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ApoC-III ASO promotes tissue LPL activity in the absence of apoE-mediated TRL clearance
Ramms, Bastian, Patel, Sohan, Nora, Chelsea, Pessentheiner, Ariane R., Chang, Max W., Green, Courtney R., Golden, Gregory J., Secrest, Patrick, Krauss, Ronald M., Metallo, Christian M., Benner, Christopher, Alexander, Veronica J., Witztum, Joseph L., Tsimikas, Sotirios, Esko, Jeffrey D., Gordts, Philip L.S.M.
Published in Journal of lipid research (01.08.2019)
Published in Journal of lipid research (01.08.2019)
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Inverse hormesis of cancer growth mediated by narrow ranges of tumor-directed antibodies
Pearce, Oliver M. T., Läubli, Heinz, Verhagen, Andrea, Secrest, Patrick, Zhang, Jiquan, Varki, Nissi M., Crocker, Paul R., Bui, Jack D., Varki, Ajit
Published in Proceedings of the National Academy of Sciences - PNAS (22.04.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (22.04.2014)
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Sialidases on Mammalian Sperm Mediate Deciduous Sialylation during Capacitation
Ma, Fang, Wu, Diana, Deng, Liwen, Secrest, Patrick, Zhao, June, Varki, Nissi, Lindheim, Steven, Gagneux, Pascal
Published in The Journal of biological chemistry (02.11.2012)
Published in The Journal of biological chemistry (02.11.2012)
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Human Xeno-Autoantibodies against a Non-Human Sialic Acid Serve as Novel Serum Biomarkers and Immunotherapeutics in Cancer
PADLER-KARAVANI, Vered, HURTADO-ZIOLA, Nancy, SINGER, Oded, GHADERI, Darius, VERMA, Inder M, LIU, Yu-Tsueng, MESSER, Karen, XI CHEN, VARKI, Ajit, SCHWAB, Richard, MINYA PU, HAI YU, SHENGSHU HUANG, MUTHANA, Saddam, CHOKHAWALA, Harshal A, HONGZHI CAO, SECREST, Patrick, FRIEDMANN-MORVINSKI, Dinorah
Published in Cancer research (Chicago, Ill.) (01.05.2011)
Published in Cancer research (Chicago, Ill.) (01.05.2011)
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Sexual selection by female immunity against paternal antigens can fix loss of function alleles
Ghaderi, Darius, Springer, Stevan A, Ma, Fang, Cohen, Miriam, Secrest, Patrick, Taylor, Rachel E, Varki, Ajit, Gagneux, Pascal
Published in Proceedings of the National Academy of Sciences - PNAS (25.10.2011)
Published in Proceedings of the National Academy of Sciences - PNAS (25.10.2011)
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Siglec receptors impact mammalian lifespan by modulating oxidative stress
Schwarz, Flavio, Pearce, Oliver M T, Wang, Xiaoxia, Samraj, Annie N, Läubli, Heinz, Garcia, Javier O, Lin, Hongqiao, Fu, Xiaoming, Garcia-Bingman, Andrea, Secrest, Patrick, Romanoski, Casey E, Heyser, Charles, Glass, Christopher K, Hazen, Stanley L, Varki, Nissi, Varki, Ajit, Gagneux, Pascal
Published in eLife (07.04.2015)
Published in eLife (07.04.2015)
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Target Cell Expression of Suppressor of Cytokine Signaling-1 Prevents Diabetes in the NOD Mouse
FLODSTRÖM-TULLBERG, Malin, YADAV, Deepak, HÄGERKVIST, Robert, TSAI, Devin, SECREST, Patrick, STOTLAND, Alexandr, SARVETNICK, Nora
Published in Diabetes (New York, N.Y.) (01.11.2003)
Published in Diabetes (New York, N.Y.) (01.11.2003)
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Resistance of the target islet tissue to autoimmune destruction contributes to genetic susceptibility in Type 1 diabetes
Hill, Natasha J, Stotland, Aleksandr, Solomon, Michelle, Secrest, Patrick, Getzoff, Elizabeth, Sarvetnick, Nora
Published in Biology direct (25.01.2007)
Published in Biology direct (25.01.2007)
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A Mouse Model for Dietary Xenosialitis: ANTIBODIES TO XENOGLYCAN CAN REDUCE FERTILITY
Ma, Fang, Deng, Liwen, Secrest, Patrick, Shi, Linda, Zhao, June, Gagneux, Pascal
Published in The Journal of biological chemistry (26.08.2016)
Published in The Journal of biological chemistry (26.08.2016)
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Sialoglycan-binding patterns of bacterial AB5 toxin B subunits correlate with host range and toxicity, indicating evolution independent of A subunits
Khan, Naazneen, Sasmal, Aniruddha, Khedri, Zahra, Secrest, Patrick, Verhagen, Andrea, Srivastava, Saurabh, Varki, Nissi, Chen, Xi, Yu, Hai, Beddoe, Travis, Paton, Adrienne W., Paton, James C., Varki, Ajit
Published in The Journal of biological chemistry (01.05.2022)
Published in The Journal of biological chemistry (01.05.2022)
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Increased LL37 in psoriasis and other inflammatory disorders promotes LDL uptake and atherosclerosis
Nakamura, Yoshiyuki, Kulkarni, Nikhil N, Takahashi, Toshiya, Alimohamadi, Haleh, Dokoshi, Tatsuya, Liu, Edward, Shia, Michael, Numata, Tomofumi, Luo, Elizabeth Wc, Gombart, Adrian F, Yang, Xiaohong, Secrest, Patrick, Gordts, Philip Lsm, Tsimikas, Sotirios, Wong, Gerard Cl, Gallo, Richard L
Published in The Journal of clinical investigation (01.03.2024)
Published in The Journal of clinical investigation (01.03.2024)
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Altered sphingolipid biosynthetic flux and lipoprotein trafficking contribute to trans-fat-induced atherosclerosis
Gengatharan, Jivani M., Handzlik, Michal K., Chih, Zoya Y., Ruchhoeft, Maureen L., Secrest, Patrick, Ashley, Ethan L., Green, Courtney R., Wallace, Martina, Gordts, Philip L.S.M., Metallo, Christian M.
Published in Cell metabolism (13.11.2024)
Published in Cell metabolism (13.11.2024)
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Increased LL37 in psoriasis and other inflammatory disorders promotes LDL uptake and atherosclerosis
Nakamura, Yoshiyuki, Kulkarni, Nikhil N, Takahashi, Toshiya, Alimohamadi, Haleh, Dokoshi, Tatsuya, Liu, Edward, Shia, Michael, Numata, Tomofumi, Luo, Elizabeth W C, Combart, Adrian F, Yang, Xiaohong, Secrest, Patrick, Cordts, Philip L S M, Tsimikas, Sotirios, Wong, Gerard C L, Gallo, Richard L
Published in The Journal of clinical investigation (01.03.2024)
Published in The Journal of clinical investigation (01.03.2024)
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Effects of Early Life Oral Arsenic Exposure on Intestinal Tract Development and Lipid Homeostasis in Neonatal Mice: Implications for NAFLD Development
Yang, Xiaojing, Weber, André A, Mennillo, Elvira, Secrest, Patrick, Chang, Max, Wong, Samantha, Le, Sabrina, Liu, Junlai, Benner, Christopher W, Karin, Michael, Gordts, Philip L S M, Tukey, Robert H, Chen, Shujuan
Published in Environmental health perspectives (01.09.2023)
Published in Environmental health perspectives (01.09.2023)
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Development and applications of sialoglycan-recognizing probes (SGRPs) with defined specificities: exploring the dynamic mammalian sialoglycome
Srivastava, Saurabh, Verhagen, Andrea, Sasmal, Aniruddha, Wasik, Brian R, Diaz, Sandra, Yu, Hai, Bensing, Barbara A, Khan, Naazneen, Khedri, Zahra, Secrest, Patrick, Sullam, Paul, Varki, Nissi, Chen, Xi, Parrish, Colin R, Varki, Ajit
Published in Glycobiology (Oxford) (22.11.2022)
Published in Glycobiology (Oxford) (22.11.2022)
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A Mouse Model for Dietary Xenosialitis
Ma, Fang, Deng, Liwen, Secrest, Patrick, Shi, Linda, Zhao, June, Gagneux, Pascal
Published in The Journal of biological chemistry (26.08.2016)
Published in The Journal of biological chemistry (26.08.2016)
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Gut bacteria responding to dietary change encode sialidases that exhibit preference for red meat-associated carbohydrates
Zaramela, Livia S., Martino, Cameron, Alisson-Silva, Frederico, Rees, Steven D., Diaz, Sandra L., Chuzel, Léa, Ganatra, Mehul B., Taron, Christopher H., Secrest, Patrick, Zuñiga, Cristal, Huang, Jianbo, Siegel, Dionicio, Chang, Geoffrey, Varki, Ajit, Zengler, Karsten
Published in Nature microbiology (01.12.2019)
Published in Nature microbiology (01.12.2019)
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Hepatocyte Heparan Sulfate Is Required for Adeno-Associated Virus 2 but Dispensable for Adenovirus 5 Liver Transduction In Vivo
Zaiss, Anne K, Foley, Erin M, Lawrence, Roger, Schneider, Lina S, Hoveida, Hamidreza, Secrest, Patrick, Catapang, Arthur B, Yamaguchi, Yu, Alemany, Ramon, Shayakhmetov, Dmitry M, Esko, Jeffrey D, Herschman, Harvey R
Published in Journal of virology (01.01.2016)
Published in Journal of virology (01.01.2016)
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