Eradication of Tumors through Simultaneous Ablation of CD276/B7-H3-Positive Tumor Cells and Tumor Vasculature
Seaman, Steven, Zhu, Zhongyu, Saha, Saurabh, Zhang, Xiaoyan M., Yang, Mi Young, Hilton, Mary Beth, Morris, Karen, Szot, Christopher, Morris, Holly, Swing, Deborah A., Tessarollo, Lino, Smith, Sean W., Degrado, Sylvia, Borkin, Dmitry, Jain, Nareshkumar, Scheiermann, Julia, Feng, Yang, Wang, Yanping, Li, Jinyu, Welsch, Dean, DeCrescenzo, Gary, Chaudhary, Amit, Zudaire, Enrique, Klarmann, Kimberly D., Keller, Jonathan R., Dimitrov, Dimiter S., St. Croix, Brad
Published in Cancer cell (10.04.2017)
Published in Cancer cell (10.04.2017)
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Tumor stroma-targeted antibody-drug conjugate triggers localized anticancer drug release
Szot, Christopher, Saha, Saurabh, Zhang, Xiaoyan M, Zhu, Zhongyu, Hilton, Mary Beth, Morris, Karen, Seaman, Steven, Dunleavey, James M, Hsu, Kuo-Sheng, Yu, Guo-Jun, Morris, Holly, Swing, Deborah A, Haines, Diana C, Wang, Yanping, Hwang, Jennifer, Feng, Yang, Welsch, Dean, DeCrescenzo, Gary, Chaudhary, Amit, Zudaire, Enrique, Dimitrov, Dimiter S, St Croix, Brad
Published in The Journal of clinical investigation (01.07.2018)
Published in The Journal of clinical investigation (01.07.2018)
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GPR124 Functions as a WNT7-Specific Coactivator of Canonical β-Catenin Signaling
Posokhova, Ekaterina, Shukla, Animesh, Seaman, Steven, Volate, Suresh, Hilton, Mary Beth, Wu, Bofan, Morris, Holly, Swing, Deborah A., Zhou, Ming, Zudaire, Enrique, Rubin, Jeffrey S., St. Croix, Brad
Published in Cell reports (Cambridge) (13.01.2015)
Published in Cell reports (Cambridge) (13.01.2015)
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Cancer cell survival depends on collagen uptake into tumor-associated stroma
Hsu, Kuo-Sheng, Dunleavey, James M., Szot, Christopher, Yang, Liping, Hilton, Mary Beth, Morris, Karen, Seaman, Steven, Feng, Yang, Lutz, Emily M., Koogle, Robert, Tomassoni-Ardori, Francesco, Saha, Saurabh, Zhang, Xiaoyan M., Zudaire, Enrique, Bajgain, Pradip, Rose, Joshua, Zhu, Zhongyu, Dimitrov, Dimiter S., Cuttitta, Frank, Emenaker, Nancy J., Tessarollo, Lino, St. Croix, Brad
Published in Nature communications (18.11.2022)
Published in Nature communications (18.11.2022)
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High-resolution structural genomics reveals new therapeutic vulnerabilities in glioblastoma
Johnston, Michael J, Nikolic, Ana, Ninkovic, Nicoletta, Guilhamon, Paul, Cavalli, Florence M G, Seaman, Steven, Zemp, Franz J, Lee, John, Abdelkareem, Aly, Ellestad, Katrina, Murison, Alex, Kushida, Michelle M, Coutinho, Fiona J, Ma, Yussanne, Mungall, Andrew J, Moore, Richard, Marra, Marco A, Taylor, Michael D, Dirks, Peter B, Pugh, Trevor J, Morrissy, Sorana, St Croix, Bradley, Mahoney, Douglas J, Lupien, Mathieu, Gallo, Marco
Published in Genome research (01.08.2019)
Published in Genome research (01.08.2019)
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GPR124, an orphan G protein-coupled receptor, is required for CNS-specific vascularization and establishment of the blood-brain barrier
Cullen, Mike, Elzarrad, Mohammed K, Seaman, Steven, Zudaire, Enrique, Stevens, Janine, Yang, Mi Young, Li, Xiujie, Chaudhary, Amit, Xu, Lihong, Hilton, Mary Beth, Logsdon, Daniel, Hsiao, Emily, Stein, Erica V, Cuttitta, Frank, Haines, Diana C, Nagashima, Kunio, Tessarollo, Lino, St. Croix, Brad
Published in Proceedings of the National Academy of Sciences - PNAS (05.04.2011)
Published in Proceedings of the National Academy of Sciences - PNAS (05.04.2011)
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TEM8/ANTXR1 Blockade Inhibits Pathological Angiogenesis and Potentiates Tumoricidal Responses against Multiple Cancer Types
Chaudhary, Amit, Hilton, Mary Beth, Seaman, Steven, Haines, Diana C., Stevenson, Susan, Lemotte, Peter K., Tschantz, William R., Zhang, Xiaoyan M., Saha, Saurabh, Fleming, Tony, St. Croix, Brad
Published in Cancer cell (14.02.2012)
Published in Cancer cell (14.02.2012)
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Id1 and Id3 Maintain Steady-State Hematopoiesis by Promoting Sinusoidal Endothelial Cell Survival and Regeneration
Gadomski, Stephen, Singh, Satyendra K., Singh, Shweta, Sarkar, Tanmoy, Klarmann, Kimberly D., Berenschot, Maximillian, Seaman, Steven, Jakubison, Brad, Gudmundsson, Kristbjorn O., Lockett, Stephen, Keller, Jonathan R.
Published in Cell reports (Cambridge) (28.04.2020)
Published in Cell reports (Cambridge) (28.04.2020)
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Engineering CD276/B7-H3-targeted antibody-drug conjugates with enhanced cancer-eradicating capability
Feng, Yang, Lee, Jaewon, Yang, Liping, Hilton, Mary Beth, Morris, Karen, Seaman, Steven, Edupuganti, Veera V. Shivaji R., Hsu, Kuo-Sheng, Dower, Christopher, Yu, Guojun, So, Daeho, Bajgain, Pradip, Zhu, Zhongyu, Dimitrov, Dimiter S., Patel, Nimit L., Robinson, Christina M., Difilippantonio, Simone, Dyba, Marzena, Corbel, Amanda, Basuli, Falguni, Swenson, Rolf E., Kalen, Joseph D., Suthe, Sreedhar Reddy, Hussain, Myer, Italia, James S., Souders, Colby A., Gao, Ling, Schnermann, Martin J., St. Croix, Brad
Published in Cell reports (Cambridge) (26.12.2023)
Published in Cell reports (Cambridge) (26.12.2023)
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Host-Derived Tumor Endothelial Marker 8 Promotes the Growth of Melanoma
CULLEN, Mike, SEAMAN, Steven, CHAUDHARY, Amit, MI YOUNG YANG, HILTON, Mary Beth, LOGSDON, Daniel, HAINES, Diana C, TESSAROLLO, Lino, CROIX, Brad St
Published in Cancer research (Chicago, Ill.) (01.08.2009)
Published in Cancer research (Chicago, Ill.) (01.08.2009)
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Essential Regulation of Lung Surfactant Homeostasis by the Orphan G Protein-Coupled Receptor GPR116
Yang, Mi Young, Hilton, Mary Beth, Seaman, Steven, Haines, Diana C., Nagashima, Kunio, Burks, Christina M., Tessarollo, Lino, Ivanova, Pavlina T., Brown, H. Alex, Umstead, Todd M., Floros, Joanna, Chroneos, Zissis C., St. Croix, Brad
Published in Cell reports (Cambridge) (30.05.2013)
Published in Cell reports (Cambridge) (30.05.2013)
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Identification of a binding partner for the endothelial cell surface proteins TEM7 and TEM7R
NANDA, Akash, BUCKHAULTS, Phillip, VOGELSTEIN, Bert, KINZLER, Kenneth W, CROIX, Brad St, SEAMAN, Steven, AGRAWAL, Nishant, BOUTIN, Paula, SHANKARA, Srinivas, NACHT, Mariana, TEICHER, Beverly, STAMPFL, Jason, SINGLY, Sujay
Published in Cancer research (Chicago, Ill.) (01.12.2004)
Published in Cancer research (Chicago, Ill.) (01.12.2004)
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TEM8/ANTXR1-Specific CAR T Cells as a Targeted Therapy for Triple-Negative Breast Cancer
Byrd, Tiara T, Fousek, Kristen, Pignata, Antonella, Szot, Christopher, Samaha, Heba, Seaman, Steven, Dobrolecki, Lacey, Salsman, Vita S, Oo, Htoo Zarni, Bielamowicz, Kevin, Landi, Daniel, Rainusso, Nino, Hicks, John, Powell, Suzanne, Baker, Matthew L, Wels, Winfried S, Koch, Joachim, Sorensen, Poul H, Deneen, Benjamin, Ellis, Matthew J, Lewis, Michael T, Hegde, Meenakshi, Fletcher, Bradley S, St Croix, Brad, Ahmed, Nabil
Published in Cancer research (Chicago, Ill.) (15.01.2018)
Published in Cancer research (Chicago, Ill.) (15.01.2018)
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The B7-H3-Targeting Antibody-Drug Conjugate m276-SL-PBD Is Potently Effective Against Pediatric Cancer Preclinical Solid Tumor Models
Kendsersky, Nathan M, Lindsay, Jarrett, Kolb, E Anders, Smith, Malcolm A, Teicher, Beverly A, Erickson, Stephen W, Earley, Eric J, Mosse, Yael P, Martinez, Daniel, Pogoriler, Jennifer, Krytska, Kateryna, Patel, Khushbu, Groff, David, Tsang, Matthew, Ghilu, Samson, Wang, Yifei, Seaman, Steven, Feng, Yang, Croix, Brad St, Gorlick, Richard, Kurmasheva, Raushan, Houghton, Peter J, Maris, John M
Published in Clinical cancer research (15.05.2021)
Published in Clinical cancer research (15.05.2021)
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COX-2 inhibition potentiates antiangiogenic cancer therapy and prevents metastasis in preclinical models
Xu, Lihong, Stevens, Janine, Hilton, Mary Beth, Seaman, Steven, Conrads, Thomas P, Veenstra, Timothy D, Logsdon, Daniel, Morris, Holly, Swing, Deborah A, Patel, Nimit L, Kalen, Joseph, Haines, Diana C, Zudaire, Enrique, St Croix, Brad
Published in Science translational medicine (25.06.2014)
Published in Science translational medicine (25.06.2014)
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Journal Article
Genes that Distinguish Physiological and Pathological Angiogenesis
Seaman, Steven, Stevens, Janine, Yang, Mi Young, Logsdon, Daniel, Graff-Cherry, Cari, St. Croix, Brad
Published in Cancer cell (01.06.2007)
Published in Cancer cell (01.06.2007)
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Advanced genetic engineering to achieve in vivo targeting of adenovirus utilizing camelid single domain antibody
Lee, Myungeun, Lu, Zhi Hong, Shoemaker, Charles B., Tremblay, Jacqueline M., St. Croix, Bradley, Seaman, Steven, Gonzalez-Pastor, Rebeca, Kashentseva, Elena A., Dmitriev, Igor P., Curiel, David T.
Published in Journal of controlled release (10.06.2021)
Published in Journal of controlled release (10.06.2021)
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Abstract 6594: 4-1BB: A double-edged sword for T cells
Yang, Liping, Sheets, Timothy P., Feng, Yang, Hsu, Kuo-Sheng, Yu, Guojun, Seaman, Steven, Bajgain, Pradip, So, Daeho, Lee, Jaewon, Chari, Raj, St. Croix, Brad
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
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Initial sequencing and comparative analysis of the mouse genome
Waterston, Robert H, Lindblad-Toh, Kerstin, Birney, Ewan, Rogers, Jane, Abril, Josep F, Agarwal, Pankaj, Agarwala, Richa, Ainscough, Rachel, Alexandersson, Marina, An, Peter, Antonarakis, Stylianos E, Attwood, John, Baertsch, Robert, Bailey, Jonathon, Barlow, Karen, Beck, Stephan, Berry, Eric, Birren, Bruce, Bloom, Toby, Bork, Peer, Botcherby, Marc, Bray, Nicolas, Brent, Michael R, Brown, Daniel G, Brown, Stephen D, Bult, Carol, Burton, John, Butler, Jonathan, Campbell, Robert D, Carninci, Piero, Cawley, Simon, Chiaromonte, Francesca, Chinwalla, Asif T, Church, Deanna M, Clamp, Michele, Clee, Christopher, Collins, Francis S, Cook, Lisa L, Copley, Richard R, Coulson, Alan, Couronne, Olivier, Cuff, James, Curwen, Val, Cutts, Tim, Daly, Mark, David, Robert, Davies, Joy, Delehaunty, Kimberly D, Deri, Justin, Dermitzakis, Emmanouil T, Dewey, Colin, Dickens, Nicholas J, Diekhans, Mark, Dodge, Sheila, Dubchak, Inna, Dunn, Diane M, Eddy, Sean R, Elnitski, Laura, Emes, Richard D, Eswara, Pallavi, Eyras, Eduardo, Felsenfeld, Adam, Fewell, Ginger A, Flicek, Paul, Foley, Karen, Frankel, Wayne N, Fulton, Lucinda A, Fulton, Robert S, Furey, Terrence S, Gage, Diane, Gibbs, Richard A, Glusman, Gustavo, Gnerre, Sante, Goldman, Nick, Goodstadt, Leo, Grafham, Darren, Graves, Tina A, Green, Eric D, Gregory, Simon, Guigó, Roderic, Guyer, Mark, Hardison, Ross C, Haussler, David, Hayashizaki, Yoshihide, Hillier, LaDeana W, Hinrichs, Angela, Hlavina, Wratko, Holzer, Timothy, Hsu, Fan, Hua, Axin, Hubbard, Tim, Hunt, Adrienne, Jackson, Ian, Jaffe, David B, Johnson, L Steven, Jones, Matthew, Jones, Thomas A, Joy, Ann, Kamal, Michael, Karlsson, Elinor K
Published in Nature (London) (05.12.2002)
Published in Nature (London) (05.12.2002)
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TEM8 interacts with the cleaved C5 domain of collagen α3(VI)
NANDA, Akash, CARSON-WALTER, Eleanor B, SEAMAN, Steven, BARBER, Thomas D, STAMPFL, Jason, SINGH, Sujay, VOGELSTEIN, Bert, KINZLER, Kenneth W, CROIX, Brad St
Published in Cancer research (Chicago, Ill.) (01.02.2004)
Published in Cancer research (Chicago, Ill.) (01.02.2004)
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