Anti-human TREM2 induces microglia proliferation and reduces pathology in an Alzheimer's disease model
Wang, Shoutang, Mustafa, Meer, Yuede, Carla M, Salazar, Santiago Viveros, Kong, Philip, Long, Hua, Ward, Michael, Siddiqui, Omer, Paul, Robert, Gilfillan, Susan, Ibrahim, Adiljan, Rhinn, Hervé, Tassi, Ilaria, Rosenthal, Arnon, Schwabe, Tina, Colonna, Marco
Published in The Journal of experimental medicine (07.09.2020)
Published in The Journal of experimental medicine (07.09.2020)
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Journal Article
TREM2 activation on microglia promotes myelin debris clearance and remyelination in a model of multiple sclerosis
Cignarella, Francesca, Filipello, Fabia, Bollman, Bryan, Cantoni, Claudia, Locca, Alberto, Mikesell, Robert, Manis, Melissa, Ibrahim, Adiljan, Deng, Li, Benitez, Bruno A., Cruchaga, Carlos, Licastro, Danilo, Mihindukulasuriya, Kathie, Harari, Oscar, Buckland, Michael, Holtzman, David M., Rosenthal, Arnon, Schwabe, Tina, Tassi, Ilaria, Piccio, Laura
Published in Acta neuropathologica (01.10.2020)
Published in Acta neuropathologica (01.10.2020)
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Journal Article
Latozinemab, a novel progranulin-elevating therapy for frontotemporal dementia
Kurnellas, Michael, Mitra, Ananya, Schwabe, Tina, Paul, Robert, Arrant, Andrew E, Roberson, Erik D, Ward, Michael, Yeh, Felix, Long, Hua, Rosenthal, Arnon
Published in Journal of translational medicine (15.06.2023)
Published in Journal of translational medicine (15.06.2023)
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Journal Article
The cAMP effector PKA mediates Moody GPCR signaling in Drosophila blood-brain barrier formation and maturation
Li, Xiaoling, Fetter, Richard, Schwabe, Tina, Jung, Christophe, Liu, Liren, Steller, Hermann, Gaul, Ulrike
Published in eLife (12.08.2021)
Published in eLife (12.08.2021)
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Journal Article
Preclinical and first-in-human evaluation of AL002, a novel TREM2 agonistic antibody for Alzheimer's disease
Long, Hua, Simmons, Adam, Mayorga, Arthur, Burgess, Brady, Nguyen, Tuan, Budda, Balasubrahmanyam, Rychkova, Anna, Rhinn, Herve, Tassi, Ilaria, Ward, Michael, Yeh, Felix, Schwabe, Tina, Paul, Robert, Kenkare-Mitra, Sara, Rosenthal, Arnon
Published in Alzheimer's research & therapy (23.10.2024)
Published in Alzheimer's research & therapy (23.10.2024)
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Journal Article
Uncoupling of Voltage- and Ligand-Induced Activation in HCN2 Channels by Glycine Inserts
Yüksel, Sezin, Bonus, Michele, Schwabe, Tina, Pfleger, Christopher, Zimmer, Thomas, Enke, Uta, Saß, Inga, Gohlke, Holger, Benndorf, Klaus, Kusch, Jana
Published in Frontiers in physiology (25.08.2022)
Published in Frontiers in physiology (25.08.2022)
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Journal Article
GPCR Signaling Is Required for Blood-Brain Barrier Formation in Drosophila
Schwabe, Tina, Bainton, Roland J., Fetter, Richard D., Heberlein, Ulrike, Gaul, Ulrike
Published in Cell (07.10.2005)
Published in Cell (07.10.2005)
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Journal Article
Functional and structural characterization of interactions between opposite subunits in HCN pacemaker channels
Kondapuram, Mahesh, Frieg, Benedikt, Yüksel, Sezin, Schwabe, Tina, Sattler, Christian, Lelle, Marco, Schweinitz, Andrea, Schmauder, Ralf, Benndorf, Klaus, Gohlke, Holger, Kusch, Jana
Published in Communications biology (09.05.2022)
Published in Communications biology (09.05.2022)
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Journal Article
Juvenile Emotional Experience Alters Synaptic Composition in the Rodent Cortex, Hippocampus, and Lateral Amygdala
Poeggel, Gerd, Helmeke, Carina, Abraham, Andreas, Schwabe, Tina, Friedrich, Patricia, Braun, Katharina
Published in Proceedings of the National Academy of Sciences - PNAS (23.12.2003)
Published in Proceedings of the National Academy of Sciences - PNAS (23.12.2003)
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Journal Article
More than just glue: The diverse roles of cell adhesion molecules in the Drosophila nervous system
Schwabe, Tina, Gontang, Allison C., Clandinin, Thomas R.
Published in Cell adhesion & migration (01.01.2009)
Published in Cell adhesion & migration (01.01.2009)
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Journal Article
Single-molecule observation of binding cooperativity in non-activated pacemaker channels
Kuschke, Stefan, Thon, Susanne, Schwabe, Tina, Benndorf, Klaus, Schmauder, Ralf
Published in Biophysical journal (11.02.2022)
Published in Biophysical journal (11.02.2022)
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Journal Article
cAMP binding to closed pacemaker ion channels is cooperative
Kuschke, Stefan, Thon, Susanne, Sattler, Christian, Schwabe, Tina, Benndorf, Klaus, Schmauder, Ralf
Published in Proceedings of the National Academy of Sciences - PNAS (27.02.2024)
Published in Proceedings of the National Academy of Sciences - PNAS (27.02.2024)
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Journal Article
Ligand binding to resting pacemaker channels is cooperative in native membranes
Kuschke, Stefan, Thon, Susanne, Schwabe, Tina, Sattler, Christian, Benndorf, Klaus, Schmauder, Ralf
Published in Biophysical journal (08.02.2024)
Published in Biophysical journal (08.02.2024)
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Journal Article
Stepwise activation of a class C GPCR begins with millisecond dimer rearrangement
Grushevskyi, Eugene O., Kukaj, Taulant, Schmauder, Ralf, Bock, Andreas, Zabel, Ulrike, Schwabe, Tina, Benndorf, Klaus, Lohse, Martin J.
Published in Proceedings of the National Academy of Sciences - PNAS (14.05.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (14.05.2019)
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Journal Article
AL002c‐mediated reduction in amyloid β pathology is reflected by changes in plasma Alzheimer’s disease biomarkers in 5XFAD mice
Burgess, Brady, Ibrahim, Adiljan, Stansley, Branden, Schwabe, Tina, Wang, Shoutang, Colonna, Marco, Tassi, Ilaria
Published in Alzheimer's & dementia (01.12.2023)
Published in Alzheimer's & dementia (01.12.2023)
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Journal Article
Relating ligand binding to activation gating in P2X2 receptors using a novel fluorescent ATP derivative
Sattler, Christian, Schmauder, Ralf, Schwabe, Tina, Schweinitz, Andrea, Unzeitig, Christopher, Schwede, Frank, Otte, Maik, Benndorf, Klaus
Published in Journal of neurochemistry (01.08.2020)
Published in Journal of neurochemistry (01.08.2020)
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