Monitoring Count Time Series in R : Aberration Detection in Public Health Surveillance
Salmon, Maëlle, Schumacher, Dirk, Höhle, Michael
Published in Journal of statistical software (01.05.2016)
Published in Journal of statistical software (01.05.2016)
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Molecular dissection of colorectal cancer in pre-clinical models identifies biomarkers predicting sensitivity to EGFR inhibitors
Schütte, Moritz, Risch, Thomas, Abdavi-Azar, Nilofar, Boehnke, Karsten, Schumacher, Dirk, Keil, Marlen, Yildiriman, Reha, Jandrasits, Christine, Borodina, Tatiana, Amstislavskiy, Vyacheslav, Worth, Catherine L., Schweiger, Caroline, Liebs, Sandra, Lange, Martin, Warnatz, Hans- Jörg, Butcher, Lee M., Barrett, James E., Sultan, Marc, Wierling, Christoph, Golob-Schwarzl, Nicole, Lax, Sigurd, Uranitsch, Stefan, Becker, Michael, Welte, Yvonne, Regan, Joseph Lewis, Silvestrov, Maxine, Kehler, Inge, Fusi, Alberto, Kessler, Thomas, Herwig, Ralf, Landegren, Ulf, Wienke, Dirk, Nilsson, Mats, Velasco, Juan A., Garin-Chesa, Pilar, Reinhard, Christoph, Beck, Stephan, Schäfer, Reinhold, Regenbrecht, Christian R. A., Henderson, David, Lange, Bodo, Haybaeck, Johannes, Keilholz, Ulrich, Hoffmann, Jens, Lehrach, Hans, Yaspo, Marie-Laure
Published in Nature communications (10.02.2017)
Published in Nature communications (10.02.2017)
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Non-Canonical Hedgehog Signaling Is a Positive Regulator of the WNT Pathway and Is Required for the Survival of Colon Cancer Stem Cells
Regan, Joseph L., Schumacher, Dirk, Staudte, Stephanie, Steffen, Andreas, Haybaeck, Johannes, Keilholz, Ulrich, Schweiger, Caroline, Golob-Schwarzl, Nicole, Mumberg, Dominik, Henderson, David, Lehrach, Hans, Regenbrecht, Christian R.A., Schäfer, Reinhold, Lange, Martin
Published in Cell reports (Cambridge) (05.12.2017)
Published in Cell reports (Cambridge) (05.12.2017)
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Heterogeneous pathway activation and drug response modelled in colorectal-tumor-derived 3D cultures
Schumacher, Dirk, Andrieux, Geoffroy, Boehnke, Karsten, Keil, Marlen, Silvestri, Alessandra, Silvestrov, Maxine, Keilholz, Ulrich, Haybaeck, Johannes, Erdmann, Gerrit, Sachse, Christoph, Templin, Markus, Hoffmann, Jens, Boerries, Melanie, Schäfer, Reinhold, Regenbrecht, Christian R A
Published in PLoS genetics (29.03.2019)
Published in PLoS genetics (29.03.2019)
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Assay Establishment and Validation of a High-Throughput Screening Platform for Three-Dimensional Patient-Derived Colon Cancer Organoid Cultures
Boehnke, Karsten, Iversen, Philip W., Schumacher, Dirk, Lallena, María José, Haro, Rubén, Amat, Joaquín, Haybaeck, Johannes, Liebs, Sandra, Lange, Martin, Schäfer, Reinhold, Regenbrecht, Christian R. A., Reinhard, Christoph, Velasco, Juan A.
Published in Journal of biomolecular screening (01.10.2016)
Published in Journal of biomolecular screening (01.10.2016)
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Network quantification of EGFR signaling unveils potential for targeted combination therapy
Klinger, Bertram, Sieber, Anja, Fritsche‐Guenther, Raphaela, Witzel, Franziska, Berry, Leanne, Schumacher, Dirk, Yan, Yibing, Durek, Pawel, Merchant, Mark, Schäfer, Reinhold, Sers, Christine, Blüthgen, Nils
Published in Molecular systems biology (2013)
Published in Molecular systems biology (2013)
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DNA copy number changes define spatial patterns of heterogeneity in colorectal cancer
Mamlouk, Soulafa, Childs, Liam Harold, Aust, Daniela, Heim, Daniel, Melching, Friederike, Oliveira, Cristiano, Wolf, Thomas, Durek, Pawel, Schumacher, Dirk, Bläker, Hendrik, von Winterfeld, Moritz, Gastl, Bastian, Möhr, Kerstin, Menne, Andrea, Zeugner, Silke, Redmer, Torben, Lenze, Dido, Tierling, Sascha, Möbs, Markus, Weichert, Wilko, Folprecht, Gunnar, Blanc, Eric, Beule, Dieter, Schäfer, Reinhold, Morkel, Markus, Klauschen, Frederick, Leser, Ulf, Sers, Christine
Published in Nature communications (25.01.2017)
Published in Nature communications (25.01.2017)
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Exposure Patterns Driving Ebola Transmission in West Africa: A Retrospective Observational Study
Agua-Agum, Junerlyn, Ariyarajah, Archchun, Aylward, Bruce, Bawo, Luke, Bilivogui, Pepe, Blake, Isobel M, Brennan, Richard J, Cawthorne, Amy, Cleary, Eilish, Clement, Peter, Conteh, Roland, Cori, Anne, Dafae, Foday, Dahl, Benjamin, Dangou, Jean-Marie, Diallo, Boubacar, Donnelly, Christl A, Dorigatti, Ilaria, Dye, Christopher, Eckmanns, Tim, Fallah, Mosoka, Ferguson, Neil M, Fiebig, Lena, Fraser, Christophe, Garske, Tini, Gonzalez, Lice, Hamblion, Esther, Hamid, Nuha, Hersey, Sara, Hinsley, Wes, Jambei, Amara, Jombart, Thibaut, Kargbo, David, Keita, Sakoba, Kinzer, Michael, George, Fred Kuti, Godefroy, Beatrice, Gutierrez, Giovanna, Kannangarage, Niluka, Mills, Harriet L, Moller, Thomas, Meijers, Sascha, Mohamed, Yasmine, Morgan, Oliver, Nedjati-Gilani, Gemma, Newton, Emily, Nouvellet, Pierre, Nyenswah, Tolbert, Perea, William, Perkins, Devin, Riley, Steven, Rodier, Guenael, Rondy, Marc, Sagrado, Maria, Savulescu, Camelia, Schafer, Ilana J, Schumacher, Dirk, Seyler, Thomas, Shah, Anita, Van Kerkhove, Maria D, Wesseh, C Samford, Yoti, Zabulon
Published in PLoS medicine (15.11.2016)
Published in PLoS medicine (15.11.2016)
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Timeliness in the German surveillance system for infectious diseases: Amendment of the infection protection act in 2013 decreased local reporting time to 1 day
Schumacher, Jakob, Diercke, Michaela, Salmon, Maëlle, Czogiel, Irina, Schumacher, Dirk, Claus, Hermann, Gilsdorf, Andreas
Published in PloS one (31.10.2017)
Published in PloS one (31.10.2017)
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Journal Article
Identification of a neural development gene expression signature in colon cancer stem cells reveals a role for EGR2 in tumorigenesis
Regan, Joseph L., Schumacher, Dirk, Staudte, Stephanie, Steffen, Andreas, Lesche, Ralf, Toedling, Joern, Jourdan, Thibaud, Haybaeck, Johannes, Golob-Schwarzl, Nicole, Mumberg, Dominik, Henderson, David, Győrffy, Balázs, Regenbrecht, Christian R.A., Keilholz, Ulrich, Schäfer, Reinhold, Lange, Martin
Published in iScience (15.07.2022)
Published in iScience (15.07.2022)
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Journal Article
RNA sequencing of long-term label-retaining colon cancer stem cells identifies novel regulators of quiescence
Regan, Joseph L., Schumacher, Dirk, Staudte, Stephanie, Steffen, Andreas, Lesche, Ralf, Toedling, Joern, Jourdan, Thibaud, Haybaeck, Johannes, Mumberg, Dominik, Henderson, David, Győrffy, Balázs, Regenbrecht, Christian R.A., Keilholz, Ulrich, Schäfer, Reinhold, Lange, Martin
Published in iScience (25.06.2021)
Published in iScience (25.06.2021)
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Journal Article
Disease severity of the first COVID-19 wave in Germany using reporting data from the national notification system
Schilling, Julia, Lehfeld, Ann-Sophie, Schumacher, Dirk, Ullrich, Alexander, Diercke, Michaela, Buda, Silke, Haas, Walter
Published in Journal of health monitoring (01.02.2021)
Published in Journal of health monitoring (01.02.2021)
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Journal Article
After Ebola in West Africa — Unpredictable Risks, Preventable Epidemics
Agua-Agum, Junerlyn, Allegranzi, Benedetta, Ariyarajah, Archchun, Aylward, R Bruce, Blake, Isobel M, Barboza, Philippe, Bausch, Daniel, Brennan, Richard J, Clement, Peter, Coffey, Pasqualina, Cori, Anne, Donnelly, Christl A, Dorigatti, Ilaria, Drury, Patrick, Durski, Kara, Dye, Christopher, Eckmanns, Tim, Ferguson, Neil M, Fraser, Christophe, Garcia, Erika, Garske, Tini, Gasasira, Alex, Gurry, Céline, Hamblion, Esther, Hinsley, Wes, Holden, Robert, Holmes, David, Hugonnet, Stéphane, Jaramillo Gutierrez, Giovanna, Jombart, Thibaut, Kelley, Edward, Santhana, Ravi, Mahmoud, Nuha, Mills, Harriet L, Mohamed, Yasmine, Musa, Emmanuel, Naidoo, Dhamari, Nedjati-Gilani, Gemma, Newton, Emily, Norton, Ian, Nouvellet, Pierre, Perkins, Devin, Perkins, Mark, Riley, Steven, Schumacher, Dirk, Shah, Anita, Tang, Minh, Varsaneux, Olivia, Van Kerkhove, Maria D
Published in The New England journal of medicine (11.08.2016)
Published in The New England journal of medicine (11.08.2016)
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Polychlorinated metallo-siloxanes of iron, molybdenum and tungsten - structure of 1-[dicarbonyl(η 5-cyclopentadienyl)ferrio]-1,1,3,3,3-pentachlorodisiloxane
Malisch, Wolfgang, Jehle, Heinrich, Schumacher, Dirk, Binnewies, Michael, Söger, Nicola
Published in Journal of organometallic chemistry (03.02.2003)
Published in Journal of organometallic chemistry (03.02.2003)
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Iron-Fragment-Substituted Heterosiloxanes of Gallium [Cp(OC)2Fe−SiR2OGaR′2]2 (R, R′ = Alkyl, Aryl) − Structures of [Cp(OC)2Fe−SiR2OGaMe2]2 (R = Me, Ph)
Malisch, Wolfgang, Schumacher, Dirk, Schmiedeskamp, Bernd, Jehle, Heinrich, Eisner, Dirk, Schoeller, Wolfgang W., Nieger, Martin
Published in European journal of inorganic chemistry (01.06.2003)
Published in European journal of inorganic chemistry (01.06.2003)
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Journal Article
West African Ebola Epidemic after One Year — Slowing but Not Yet under Control
Agua-Agum, Junerlyn, Ariyarajah, Archchun, Aylward, Bruce, Blake, Isobel M, Brennan, Richard, Cori, Anne, Donnelly, Christl A, Dorigatti, Ilaria, Dye, Christopher, Eckmanns, Tim, Ferguson, Neil M, Formenty, Pierre, Fraser, Christophe, Garcia, Erika, Garske, Tini, Hinsley, Wes, Holmes, David, Hugonnet, Stéphane, Iyengar, Swathi, Jombart, Thibaut, Krishnan, Ravi, Meijers, Sascha, Mills, Harriet L, Mohamed, Yasmine, Nedjati-Gilani, Gemma, Newton, Emily, Nouvellet, Pierre, Pelletier, Louise, Perkins, Devin, Riley, Steven, Sagrado, Maria, Schnitzler, Johannes, Schumacher, Dirk, Shah, Anita, Van Kerkhove, Maria D, Varsaneux, Olivia, Wijekoon Kannangarage, Niluka
Published in The New England journal of medicine (05.02.2015)
Published in The New England journal of medicine (05.02.2015)
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Journal Article
Heterogeneities in the case fatality ratio in the West African Ebola outbreak 2013–2016
Garske, Tini, Cori, Anne, Ariyarajah, Archchun, Blake, Isobel M., Dorigatti, Ilaria, Eckmanns, Tim, Fraser, Christophe, Hinsley, Wes, Jombart, Thibaut, Mills, Harriet L., Nedjati-Gilani, Gemma, Newton, Emily, Nouvellet, Pierre, Perkins, Devin, Riley, Steven, Schumacher, Dirk, Shah, Anita, Van Kerkhove, Maria D., Dye, Christopher, Ferguson, Neil M., Donnelly, Christl A.
Published in Philosophical transactions of the Royal Society of London. Series B. Biological sciences (26.05.2017)
Published in Philosophical transactions of the Royal Society of London. Series B. Biological sciences (26.05.2017)
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Journal Article
Ebola Virus Disease among Children in West Africa
Agua-Agum, Junerlyn, Ariyarajah, Archchun, Blake, Isobel M, Cori, Anne, Donnelly, Christl A, Dorigatti, Ilaria, Dye, Christopher, Eckmanns, Tim, Ferguson, Neil M, Fowler, Robert A, Fraser, Christophe, Garske, Tini, Hinsley, Wes, Jombart, Thibaut, Mills, Harriet L, Murthy, Srinivas, Nedjati Gilani, Gemma, Nouvellet, Pierre, Pelletier, Louise, Riley, Steven, Schumacher, Dirk, Shah, Anita, Van Kerkhove, Maria D
Published in The New England journal of medicine (26.03.2015)
Published in The New England journal of medicine (26.03.2015)
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Journal Article
Real-time monitoring of COVID-19 dynamics using automated trend fitting and anomaly detection
Jombart, Thibaut, Ghozzi, Stéphane, Schumacher, Dirk, Taylor, Timothy J, Leclerc, Quentin J, Jit, Mark, Flasche, Stefan, Greaves, Felix, Ward, Tom, Eggo, Rosalind M, Nightingale, Emily, Meakin, Sophie, Brady, Oliver J, Medley, Graham F, Höhle, Michael, Edmunds, W John
Published in Philosophical transactions of the Royal Society of London. Series B. Biological sciences (19.07.2021)
Published in Philosophical transactions of the Royal Society of London. Series B. Biological sciences (19.07.2021)
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