The siRNA‐mediated downregulation of PD‐1 alone or simultaneously with CTLA‐4 shows enhanced in vitro CAR‐T‐cell functionality for further clinical development towards the potential use in immunotherapy of melanoma
Simon, Bianca, Harrer, Dennis C., Schuler‐Thurner, Beatrice, Schaft, Niels, Schuler, Gerold, Dörrie, Jan, Uslu, Ugur
Published in Experimental dermatology (01.07.2018)
Published in Experimental dermatology (01.07.2018)
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Journal Article
Comparison of the oncolytic activity of a replication‐competent and a replication‐deficient herpes simplex virus 1
Lindner, Georg, Walter, Annika, Magnus, Clara L., Rosenhammer, Katharina, Holoborodko, Bohdan, Koch, Victoria, Hirsch, Sarah, Grossmann, Luis, Li, Suqi, Knipe, David M., DeLuca, Neal, Schuler‐Thurner, Beatrice, Gross, Stefanie, Schwertner, Barbara, Toelge, Martina, Rohrhofer, Anette, Stöckl, Sabine, Bauer, Richard J., Knoll, Gertrud, Ehrenschwender, Martin, Haferkamp, Sebastian, Schmidt, Barbara, Schuster, Philipp
Published in Immunology (01.06.2024)
Published in Immunology (01.06.2024)
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Journal Article
Therapeutic Cancer Vaccination with Ex Vivo RNA-Transfected Dendritic Cells-An Update
Dörrie, Jan, Schaft, Niels, Schuler, Gerold, Schuler-Thurner, Beatrice
Published in Pharmaceutics (23.01.2020)
Published in Pharmaceutics (23.01.2020)
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Journal Article
The Generation of CAR-Transfected Natural Killer T Cells for the Immunotherapy of Melanoma
Simon, Bianca, Wiesinger, Manuel, März, Johannes, Wistuba-Hamprecht, Kilian, Weide, Benjamin, Schuler-Thurner, Beatrice, Schuler, Gerold, Dörrie, Jan, Uslu, Ugur
Published in International journal of molecular sciences (11.08.2018)
Published in International journal of molecular sciences (11.08.2018)
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Journal Article
The future of affordable cancer immunotherapy
Schaft, Niels, Dörrie, Jan, Schuler, Gerold, Schuler-Thurner, Beatrice, Sallam, Husam, Klein, Shiri, Eisenberg, Galit, Frankenburg, Shoshana, Lotem, Michal, Khatib, Areej
Published in Frontiers in immunology (06.09.2023)
Published in Frontiers in immunology (06.09.2023)
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Journal Article
Concurrent interaction of DCs with CD4+ and CD8+ T cells improves secondary CTL expansion: It takes three to tango
Hoyer, Stefanie, Prommersberger, Sabrina, Pfeiffer, Isabell A., Schuler‐Thurner, Beatrice, Schuler, Gerold, Dörrie, Jan, Schaft, Niels
Published in European journal of immunology (01.12.2014)
Published in European journal of immunology (01.12.2014)
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Journal Article
The use of dendritic cells in cancer immunotherapy
Schuler, Gerold, Schuler-Thurner, Beatrice, Steinman, Ralph M
Published in Current opinion in immunology (01.04.2003)
Published in Current opinion in immunology (01.04.2003)
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Journal Article
A One-Armed Phase I Dose Escalation Trial Design: Personalized Vaccination with IKKβ-Matured, RNA-Loaded Dendritic Cells for Metastatic Uveal Melanoma
Koch, Elias A T, Schaft, Niels, Kummer, Mirko, Berking, Carola, Schuler, Gerold, Hasumi, Kenichiro, Dörrie, Jan, Schuler-Thurner, Beatrice
Published in Frontiers in immunology (04.02.2022)
Published in Frontiers in immunology (04.02.2022)
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Journal Article
Stability and activity of MCSP-specific chimeric antigen receptors (CARs) depend on the scFv antigen-binding domain and the protein backbone
Krug, Christian, Birkholz, Katrin, Paulus, Alexander, Schwenkert, Michael, Schmidt, Patrick, Hoffmann, Nicole, Hombach, Andreas, Fey, Georg, Abken, Hinrich, Schuler, Gerold, Schuler-Thurner, Beatrice, Dörrie, Jan, Schaft, Niels
Published in Cancer Immunology, Immunotherapy (01.12.2015)
Published in Cancer Immunology, Immunotherapy (01.12.2015)
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Journal Article
Denileukin diftitox (ONTAK) induces a tolerogenic phenotype in dendritic cells and stimulates survival of resting Treg
Baur, Andreas S., Lutz, Manfred B., Schierer, Stephan, Beltrame, Luca, Theiner, Gabi, Zinser, Elisabeth, Ostalecki, Christian, Heidkamp, Gordon, Haendle, Ina, Erdmann, Michael, Wiesinger, Manuel, Leisgang, Waltraud, Gross, Stefanie, Pommer, Ansgar J., Kämpgen, Eckhart, Dudziak, Diana, Steinkasserer, Alexander, Cavalieri, Duccio, Schuler-Thurner, Beatrice, Schuler, Gerold
Published in Blood (26.09.2013)
Published in Blood (26.09.2013)
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Journal Article
Blood Eosinophilia is an on-Treatment Biomarker in Patients with Solid Tumors Undergoing Dendritic Cell Vaccination with Autologous Tumor-RNA
Moreira, Alvaro, Erdmann, Michael, Uslu, Ugur, Vass, Verona, Schuler, Gerold, Schuler-Thurner, Beatrice
Published in Pharmaceutics (01.03.2020)
Published in Pharmaceutics (01.03.2020)
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Journal Article
Combined cytotoxic activity of an infectious, but non‐replicative herpes simplex virus type 1 and plasmacytoid dendritic cells against tumour cells
Thomann, Sabrina, Boscheinen, Jan B., Vogel, Karin, Knipe, David M., DeLuca, Neal, Gross, Stefanie, Schuler‐Thurner, Beatrice, Schuster, Philipp, Schmidt, Barbara
Published in Immunology (01.10.2015)
Published in Immunology (01.10.2015)
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Journal Article
Block Excision of Iridociliary Tumors Enables Molecular Profiling and Immune Vaccination
Heindl, Ludwig M., MD, Koch, Konrad R., MD, Hermann, Manuel M., MD, Merkelbach-Bruse, Sabine, MD, Schultheis, Anne M., MD, Wagener, Svenja, MD, Büttner, Reinhard, MD, Mauch, Cornelia, MD, Schuler-Thurner, Beatrice, MD, Schuler, Gerold, MD, Cursiefen, Claus, MD
Published in Ophthalmology (Rochester, Minn.) (01.02.2017)
Published in Ophthalmology (Rochester, Minn.) (01.02.2017)
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Journal Article
Good Manufacturing Practice-Compliant Production and Lot-Release of Ex Vivo Expanded Regulatory T Cells As Basis for Treatment of Patients with Autoimmune and Inflammatory Disorders
Wiesinger, Manuel, Stoica, Diane, Roessner, Susanne, Lorenz, Carmen, Fischer, Anika, Atreya, Raja, Neufert, Clemens F, Atreya, Imke, Scheffold, Alexander, Schuler-Thurner, Beatrice, Neurath, Markus F, Schuler, Gerold, Voskens, Caroline J
Published in Frontiers in immunology (26.10.2017)
Published in Frontiers in immunology (26.10.2017)
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Journal Article
Generation of an Oncolytic Herpes Simplex Virus 1 Expressing Human MelanA
Boscheinen, Jan B, Thomann, Sabrina, Knipe, David M, DeLuca, Neal, Schuler-Thurner, Beatrice, Gross, Stefanie, Dörrie, Jan, Schaft, Niels, Bach, Christian, Rohrhofer, Anette, Werner-Klein, Melanie, Schmidt, Barbara, Schuster, Philipp
Published in Frontiers in immunology (2019)
Published in Frontiers in immunology (2019)
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Journal Article
Gene network-based and ensemble modeling-based selection of tumor-associated antigens with a predicted low risk of tissue damage for targeted immunotherapy
Lischer, Christopher, Eberhardt, Martin, Flamann, Cindy, Berges, Johannes, Güse, Esther, Wessely, Anja, Weich, Adrian, Retzlaff, Jimmy, Dörrie, Jan, Schaft, Niels, Wiesinger, Manuel, März, Johannes, Schuler-Thurner, Beatrice, Knorr, Harald, Gupta, Shailendra, Singh, Krishna Pal, Schuler, Gerold, Heppt, Markus Vincent, Koch, Elias Andreas Thomas, van Kleef, Nadine D, Freen-van Heeren, Julian J, Turksma, Annelies W, Wolkenhauer, Olaf, Hohberger, Bettina, Berking, Carola, Bruns, Heiko, Vera, Julio
Published in Journal for immunotherapy of cancer (09.05.2024)
Published in Journal for immunotherapy of cancer (09.05.2024)
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Journal Article
Conventional and three-dimensional photography as a tool to map distribution patterns of in-transit melanoma metastases on the lower extremity
Müller, Kilian, Berking, Carola, Voskens, Caroline, Heppt, Markus V, Heinzerling, Lucie, Koch, Elias A T, Kramer, Rafaela, Merkel, Susanne, Schuler-Thurner, Beatrice, Schellerer, Vera, Steeb, Theresa, Wessely, Anja, Erdmann, Michael
Published in Frontiers in medicine (19.01.2023)
Published in Frontiers in medicine (19.01.2023)
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Journal Article
A comparison of two types of dendritic cell as adjuvants for the induction of melanoma‐specific T‐cell responses in humans following intranodal injection
Jonuleit, Helmut, Giesecke‐Tuettenberg, Andrea, Tüting, Thomas, Thurner‐Schuler, Beatrice, Stuge, Tor B., Paragnik, Lydia, Kandemir, Ayten, Lee, Peter P., Schuler, Gerold, Knop, Jürgen, Enk, Alexander H.
Published in International journal of cancer (15.07.2001)
Published in International journal of cancer (15.07.2001)
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Journal Article
Preclinical evaluation of NF-κB-triggered dendritic cells expressing the viral oncogenic driver of Merkel cell carcinoma for therapeutic vaccination
Gerer, Kerstin F., Erdmann, Michael, Hadrup, Sine R., Lyngaa, Rikke, Martin, Lena-Marie, Voll, Reinhard E., Schuler-Thurner, Beatrice, Schuler, Gerold, Schaft, Niels, Hoyer, Stefanie, Dörrie, Jan
Published in Therapeutic advances in medical oncology (01.07.2017)
Published in Therapeutic advances in medical oncology (01.07.2017)
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Journal Article
A method for the production of cryopreserved aliquots of antigen-preloaded, mature dendritic cells ready for clinical use
Feuerstein, Bernadette, Berger, Thomas G, Maczek, Christian, Röder, Claudia, Schreiner, Doris, Hirsch, Ute, Haendle, Ina, Leisgang, Waltraud, Glaser, Anke, Kuss, Oliver, Diepgen, Thomas L, Schuler, Gerold, Schuler-Thurner, Beatrice
Published in Journal of immunological methods (01.11.2000)
Published in Journal of immunological methods (01.11.2000)
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Journal Article