Beyond Competitive Inhibition: Regulation of ABC Transporters by Kinases and Protein-Protein Interactions as Potential Mechanisms of Drug-Drug Interactions
Crawford, Rebecca R, Potukuchi, Praveen K, Schuetz, Erin G, Schuetz, John D
Published in Drug metabolism and disposition (01.05.2018)
Published in Drug metabolism and disposition (01.05.2018)
Get full text
Journal Article
Pheophorbide A: Fluorescent Bcrp Substrate to Measure Oral Drug-Drug Interactions in Real-Time In Vivo
Yasuda, Kazuto, Ganguly, Samit, Schuetz, Erin G
Published in Drug metabolism and disposition (01.11.2018)
Published in Drug metabolism and disposition (01.11.2018)
Get full text
Journal Article
Zebrafish abcb11b mutant reveals strategies to restore bile excretion impaired by bile salt export pump deficiency
Ellis, Jillian L., Bove, Kevin E., Schuetz, Erin G., Leino, Daniel, Valencia, C. Alexander, Schuetz, John D., Miethke, Alexander, Yin, Chunyue
Published in Hepatology (Baltimore, Md.) (01.04.2018)
Published in Hepatology (Baltimore, Md.) (01.04.2018)
Get full text
Journal Article
Drug transporters on arachnoid barrier cells contribute to the blood-cerebrospinal fluid barrier
Yasuda, Kazuto, Cline, Cynthia, Vogel, Peter, Onciu, Mihaela, Fatima, Soghra, Sorrentino, Brian P, Thirumaran, Ranjit K, Ekins, Sean, Urade, Yoshihiro, Fujimori, Ko, Schuetz, Erin G
Published in Drug metabolism and disposition (01.04.2013)
Published in Drug metabolism and disposition (01.04.2013)
Get full text
Journal Article
Metabolomic and transcriptomic analysis reveals endogenous substrates and metabolic adaptation in rats lacking Abcg2 and Abcb1a transporters
Ganguly, Samit, Finkelstein, David, Shaw, Timothy I, Michalek, Ryan D, Zorn, Kimberly M, Ekins, Sean, Yasuda, Kazuto, Fukuda, Yu, Schuetz, John D, Mukherjee, Kamalika, Schuetz, Erin G
Published in PloS one (13.07.2021)
Published in PloS one (13.07.2021)
Get full text
Journal Article
Polymorphic Human Sulfotransferase 2A1 Mediates the Formation of 25-Hydroxyvitamin D3-3-O-Sulfate, a Major Circulating Vitamin D Metabolite in Humans
Wong, Timothy, Wang, Zhican, Chapron, Brian D, Suzuki, Mizuki, Claw, Katrina G, Gao, Chunying, Foti, Robert S, Prasad, Bhagwat, Chapron, Alenka, Calamia, Justina, Chaudhry, Amarjit, Schuetz, Erin G, Horst, Ronald L, Mao, Qingcheng, de Boer, Ian H, Thornton, Timothy A, Thummel, Kenneth E
Published in Drug metabolism and disposition (01.04.2018)
Published in Drug metabolism and disposition (01.04.2018)
Get full text
Journal Article
Vitamin D levels do not cause vitamin-drug interactions with dexamethasone or dasatinib in mice
Annu, Kavya, Yasuda, Kazuto, Caufield, William V, Freeman, 3rd, Burgess B, Schuetz, Erin G
Published in PloS one (20.10.2021)
Published in PloS one (20.10.2021)
Get full text
Journal Article
Predictors of Variation in CYP2A6 mRNA, Protein, and Enzyme Activity in a Human Liver Bank: Influence of Genetic and Nongenetic Factors
Tanner, Julie-Anne, Prasad, Bhagwat, Claw, Katrina G, Stapleton, Patricia, Chaudhry, Amarjit, Schuetz, Erin G, Thummel, Kenneth E, Tyndale, Rachel F
Published in The Journal of pharmacology and experimental therapeutics (01.01.2017)
Published in The Journal of pharmacology and experimental therapeutics (01.01.2017)
Get full text
Journal Article
Genetic contribution to variable human CYP3A-mediated metabolism
Lamba, Jatinder K, Lin, Yvonne S, Schuetz, Erin G, Thummel, Kenneth E
Published in Advanced drug delivery reviews (18.11.2002)
Published in Advanced drug delivery reviews (18.11.2002)
Get full text
Journal Article
Piperine activates human pregnane X receptor to induce the expression of cytochrome P450 3A4 and multidrug resistance protein 1
Wang, Yue-Ming, Lin, Wenwei, Chai, Sergio C., Wu, Jing, Ong, Su Sien, Schuetz, Erin G., Chen, Taosheng
Published in Toxicology and applied pharmacology (01.10.2013)
Published in Toxicology and applied pharmacology (01.10.2013)
Get full text
Journal Article
Human UGT1A4 and UGT1A3 Conjugate 25-Hydroxyvitamin D3: Metabolite Structure, Kinetics, Inducibility, and Interindividual Variability
Wang, Zhican, Wong, Timothy, Hashizume, Takanori, Dickmann, Leslie Z, Scian, Michele, Koszewski, Nicholas J, Goff, Jesse P, Horst, Ronald L, Chaudhry, Amarjit S, Schuetz, Erin G, Thummel, Kenneth E
Published in Endocrinology (Philadelphia) (01.06.2014)
Published in Endocrinology (Philadelphia) (01.06.2014)
Get full text
Journal Article
Hepatic CYP2B6 Expression: Gender and Ethnic Differences and Relationship to CYP2B6 Genotype and CAR (Constitutive Androstane Receptor) Expression
Lamba, Vishal, Lamba, Jatinder, Yasuda, Kazuto, Strom, Stephen, Davila, Julio, Hancock, Michael L, Fackenthal, James D, Rogan, Peter K, Ring, Barbara, Wrighton, Steven A, Schuetz, Erin G
Published in The Journal of pharmacology and experimental therapeutics (01.12.2003)
Published in The Journal of pharmacology and experimental therapeutics (01.12.2003)
Get full text
Journal Article
Ontogeny and Sorafenib Metabolism
ZIMMERMAN, Eric I, ROBERTS, Justin L, LIE LI, FINKELSTEIN, David, GIBSON, Alice, CHAUDHRY, Amarjit S, SCHUETZ, Erin G, RUBNITZ, Jeffrey E, INABA, Hiroto, BAKER, Sharyn D
Published in Clinical cancer research (15.10.2012)
Published in Clinical cancer research (15.10.2012)
Get full text
Journal Article
Functional characterization of novel rare CYP2A6 variants and potential implications for clinical outcomes
El‐Boraie, Ahmed, Tanner, Julie‐Anne, Zhu, Andy Z.X., Claw, Katrina G., Prasad, Bhagwat, Schuetz, Erin G., Thummel, Kenneth E., Fukunaga, Koya, Mushiroda, Taisei, Kubo, Michiaki, Benowitz, Neal L., Lerman, Caryn, Tyndale, Rachel F.
Published in Clinical and translational science (01.01.2022)
Published in Clinical and translational science (01.01.2022)
Get full text
Journal Article
Characterization of CYP3A pharmacogenetic variation in American Indian and Alaska Native communities, targeting CYP3A41G allele function
Fohner, Alison E., Dalton, Rachel, Skagen, Kasse, Jackson, Konner, Claw, Katrina G., Hopkins, Scarlett E., Robinson, Renee, Khan, Burhan A., Prasad, Bhagwat, Schuetz, Erin G., Nickerson, Deborah A., Thornton, Timothy A., Dillard, Denise A., Boyer, Bert B., Thummel, Kenneth E., Woodahl, Erica L.
Published in Clinical and translational science (01.07.2021)
Published in Clinical and translational science (01.07.2021)
Get full text
Journal Article
Co-Regulation of CYP3A4 and CYP3A5 and Contribution to Hepatic and Intestinal Midazolam Metabolism
Lin, Yvonne S, Dowling, Amy L S, Quigley, Sean D, Farin, Federico M, Zhang, Jiong, Lamba, Jatinder, Schuetz, Erin G, Thummel, Kenneth E
Published in Molecular pharmacology (01.07.2002)
Published in Molecular pharmacology (01.07.2002)
Get full text
Journal Article
Induction of carbonyl reductase 1 (CBR1) expression in human lung tissues and lung cancer cells by the cigarette smoke constituent benzo[a]pyrene
Kalabus, James L., Cheng, Qiuying, Jamil, Raqeeb G., Schuetz, Erin G., Blanco, Javier G.
Published in Toxicology letters (20.06.2012)
Published in Toxicology letters (20.06.2012)
Get full text
Journal Article
Interactions between Hepatic Mrp4 and Sult2a as Revealed by the Constitutive Androstane Receptor and Mrp4 Knockout Mice
Assem, Mahfoud, Schuetz, Erin G, Leggas, Markos, Sun, Daxi, Yasuda, Kazuto, Reid, Glen, Zelcer, Noam, Adachi, Masashi, Strom, Stephen, Evans, Ronald M, Moore, David D, Borst, Piet, Schuetz, John D
Published in The Journal of biological chemistry (21.05.2004)
Published in The Journal of biological chemistry (21.05.2004)
Get full text
Journal Article
Pharmacogenetics of Deoxycytidine Kinase: Identification and Characterization of Novel Genetic Variants
Lamba, Jatinder K, Crews, Kristine, Pounds, Stanley, Schuetz, Erin G, Gresham, Jessica, Gandhi, Varsha, Plunkett, William, Rubnitz, Jeffrey, Ribeiro, Raul
Published in The Journal of pharmacology and experimental therapeutics (01.12.2007)
Published in The Journal of pharmacology and experimental therapeutics (01.12.2007)
Get full text
Journal Article