Critical assessment of human antibody generation in humanized mouse models
Villaudy, Julien, Schotte, Remko, Legrand, Nicolas, Spits, Hergen
Published in Journal of immunological methods (01.08.2014)
Published in Journal of immunological methods (01.08.2014)
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Development of human plasmacytoid dendritic cells depends on the combined action of the basic helix-loop-helix factor E2-2 and the Ets factor Spi-B
Nagasawa, Maho, Schmidlin, Heike, Hazekamp, Mark G, Schotte, Remko, Blom, Bianca
Published in European journal of immunology (01.09.2008)
Published in European journal of immunology (01.09.2008)
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Functional CD47/signal regulatory protein alpha (SIRPα) interaction is required for optimal human T- and natural killer- (NK) cell homeostasis in vivo
Legrand, Nicolas, Huntington, Nicholas D, Nagasawa, Maho, Bakker, Arjen Q, Schotte, Remko, Strick-Marchand, Hélène, de Geus, Sandra J, Pouw, Stephan M, Böhne, Martino, Voordouw, Arie, Weijer, Kees, Di Santo, James P, Spits, Hergen
Published in Proceedings of the National Academy of Sciences - PNAS (09.08.2011)
Published in Proceedings of the National Academy of Sciences - PNAS (09.08.2011)
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STAT5 regulates the self-renewal capacity and differentiation of human memory B cells and controls Bcl-6 expression
Spits, Hergen, Scheeren, Ferenc A, Naspetti, Marianne, Diehl, Sean, Schotte, Remko, Nagasawa, Maho, Wijnands, Erwin, Gimeno, Ramon, Vyth-Dreese, Florry A, Blom, Bianca
Published in Nature immunology (01.03.2005)
Published in Nature immunology (01.03.2005)
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Journal Article
Spi-B inhibits human plasma cell differentiation by repressing BLIMP1 and XBP-1 expression
Schmidlin, Heike, Diehl, Sean A., Nagasawa, Maho, Scheeren, Ferenc A., Schotte, Remko, Uittenbogaart, Christel H., Spits, Hergen, Blom, Bianca
Published in Blood (01.09.2008)
Published in Blood (01.09.2008)
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721 AT1412, a patient-derived CD9 antibody in preclinical development promoting tumor immune infiltration and inducing tumor rejection
Schotte, Remko, Villaudy, Julien, Kedde, Martijn, Pos, Wouter, Go, Daniel, Fatmawati, Christien, Moiset, Gemma, Yasuda, Etsuko, Cercel, Madalina, Frankin, Esmay, Hal, Susan van, Helden, Pauline van, Verdegaal, Els, Burg, Sjoerd van der, Spits, Hergen, Eenennaam, Hans van
Published in Journal for immunotherapy of cancer (01.11.2020)
Published in Journal for immunotherapy of cancer (01.11.2020)
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Prospects and limitations of T cell receptor gene therapy
Jorritsma, Annelies, Schotte, Remko, Coccoris, Miriam, de Witte, Moniek A, Schumacher, Ton N M
Published in Current gene therapy (01.08.2011)
Published in Current gene therapy (01.08.2011)
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Journal Article
High-throughput epitope discovery reveals frequent recognition of neo-antigens by CD4+ T cells in human melanoma
Linnemann, Carsten, van Buuren, Marit M, Bies, Laura, Verdegaal, Els M E, Schotte, Remko, Calis, Jorg J A, Behjati, Sam, Velds, Arno, Hilkmann, Henk, Atmioui, Dris el, Visser, Marten, Stratton, Michael R, Haanen, John B A G, Spits, Hergen, van der Burg, Sjoerd H, Schumacher, Ton N M
Published in Nature medicine (01.01.2015)
Published in Nature medicine (01.01.2015)
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Neoantigen landscape dynamics during human melanoma–T cell interactions
Verdegaal, Els M. E., de Miranda, Noel F. C. C., Visser, Marten, Harryvan, Tom, van Buuren, Marit M., Andersen, Rikke S., Hadrup, Sine R., van der Minne, Caroline E., Schotte, Remko, Spits, Hergen, Haanen, John B. A. G., Kapiteijn, Ellen H. W., Schumacher, Ton N., van der Burg, Sjoerd H.
Published in Nature (London) (04.08.2016)
Published in Nature (London) (04.08.2016)
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High-throughput identification of antigen-specific TCRs by TCR gene capture
Linnemann, Carsten, Heemskerk, Bianca, Kvistborg, Pia, Kluin, Roelof J C, Bolotin, Dmitriy A, Chen, Xiaojing, Bresser, Kaspar, Nieuwland, Marja, Schotte, Remko, Michels, Samira, Gomez-Eerland, Raquel, Jahn, Lorenz, Hombrink, Pleun, Legrand, Nicolas, Shu, Chengyi Jenny, Mamedov, Ilgar Z, Velds, Arno, Blank, Christian U, Haanen, John B A G, Turchaninova, Maria A, Kerkhoven, Ron M, Spits, Hergen, Hadrup, Sine Reker, Heemskerk, Mirjam H M, Blankenstein, Thomas, Chudakov, Dmitriy M, Bendle, Gavin M, Schumacher, Ton N M
Published in Nature medicine (01.11.2013)
Published in Nature medicine (01.11.2013)
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Abstract 532: A patient-derived anti-CD9 antibody induces tumor rejection and synergistically enhances anti-PD1 activity
Schotte, Remko, Villaudy, Julien, Kedde, Martijn, Pos, Wouter, Wagner, Koen, Neviani, Viviana, Go, Daniel, Yasuda, Etsuko, Fatmawati, Christien, Verdegaal, Els, van Hal, Susan, Claasen, Yvonne, van Eenennaam, Hans, van Helden, Pauline, Gros, Piet, van der Burg, Sjoerd, Spits, Hergen
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Tumor infiltrating lymphocytes (TIL) therapy in metastatic melanoma: boosting of neoantigen-specific T cell reactivity and long-term follow-up
van den Berg, Joost H, Heemskerk, Bianca, van Rooij, Nienke, Gomez-Eerland, Raquel, Michels, Samira, van Zon, Maaike, de Boer, Renate, Bakker, Noor A M, Jorritsma-Smit, Annelies, van Buuren, Marit M, Kvistborg, Pia, Spits, Hergen, Schotte, Remko, Mallo, Henk, Karger, Matthias, van der Hage, Joris A, Wouters, Michel W J M, Pronk, Loes M, Geukes Foppen, Marnix H, Blank, Christian U, Beijnen, Jos H, Nuijen, Bastiaan, Schumacher, Ton N, Haanen, John B A G
Published in Journal for immunotherapy of cancer (01.08.2020)
Published in Journal for immunotherapy of cancer (01.08.2020)
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Journal Article
Preclinical Development of AT1412, a Patient Derived CD9 Antibody That Does Not Induce Thrombosis for Treatment of B ALL
Schotte, Remko, Villaudy, Julien, De Jong, Greta, Neviani, Viviana, Pos, Wouter, Levie, Sophie E, Go, Daniel M, Yasuda, Etsuko, Frankin, Esmay, Cercel, Madalina, van Hal-van Veen, Susan E, van de Berg, Dorien, Szabó, Anikó, Fatmawati, Christien, Kedde, Martijn, Claassen, Yvonne, Horbach, Sjeng, Rijneveld, Anita W, Gros, Piet, Spits, Hergen, Hazenberg, Mette D, van Eenennaam, Hans
Published in Blood (05.11.2020)
Published in Blood (05.11.2020)
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Journal Article
Abstract 531: AT1412, a patient-derived antibody in development for the treatment of CD9-positive precursor B-acute lymphoblastic leukemia
de Jong, Greta, Levie, Sophie E., Schotte, Remko, Pos, Wouter, Go, Daniel, Yasuda, Etsuko, Cercel, Madalina, van Hal, Susan E., Frankin, Esmay, Szabo, Aniko, Kedde, Martijn, Verdegaal, Els, Villaudy, Julien, van der Burg, Sjoerd, van Helden, Pauline M., van Eenennaam, Hans, Spits, Hergen, van Rijneveld, Anita, Hazenberg, Mette D.
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Abstract 542: T-cell engager bispecific formats of an AML patient-derived antibody targeting a unique sialylated CD43 epitope induce kill of melanoma cells in vitro and in vivo
de Jong, Greta, Bartels, Lina, Kedde, Martijn, Verdegaal, Els, Gillissen, Marijn A., Levie, Sophie E., Cercel, Madalina G., van Hal-van Veen, Susan E., Fatmawati, Christien, van de Berg, Dorien, Yasuda, Etsuko, Claassen, Yvonne, Bakker, Arjen Q., Schotte, Remko, Villaudy, Julien, Wagner, Koen, Spits, Hergen, Hazenberg, Mette D., van Helden, Pauline M.
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Journal Article
Abstract LB-200: A patient derived antibody targeting the tetraspanin CD9 synergistically inhibits tumor growth with an anti PD1 antibody
Schotte, Remko, Helden, Pauline van, Go, Daniel, Fatmawati, Christien, Verdegaal, Els, Bru, Camile, Villaudy, Julien, Wagner, Koen, Burg, Sjoerd van der, Spits, Hergen, Pos, Wouter
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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Journal Article
AT1412, a Patient-Derived Antibody in Development for the Treatment of CD9 Positive Precursor B-Acute Lymphoblastic Leukemia
De Jong, Greta, Levie, Sophie E, Schotte, Remko, Pos, Wouter, Go, Daniel, Yasuda, Etsuko, Cercel, Madalina, van Hal-van Veen, Susan E, Frankin, Esmay, Szabó, Anikó, Villaudy, Julien, van Helden, Pauline M, van Eenennaam, Hans, Spits, Hergen, Rijneveld, Anita W, Hazenberg, Mette D
Published in Blood (13.11.2019)
Published in Blood (13.11.2019)
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Synergy between IL-15 and Id2 promotes the expansion of human NK progenitor cells, which can be counteracted by the E protein HEB required to drive T cell development
Schotte, Remko, Dontje, Wendy, Nagasawa, Maho, Yasuda, Yuko, Bakker, Arjen Q, Spits, Hergen, Blom, Bianca
Published in The Journal of immunology (1950) (15.06.2010)
Published in The Journal of immunology (1950) (15.06.2010)
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Erratum: Corrigendum: High-throughput epitope discovery reveals frequent recognition of neo-antigens by CD4+ T cells in human melanoma
Linnemann, Carsten, van Buuren, Marit M, Bies, Laura, Verdegaal, Els M E, Schotte, Remko, Calis, Jorg J A, Behjati, Sam, Velds, Arno, Hilkmann, Henk, el Atmioui, Dris, Visser, Marten, Stratton, Michael R, Haanen, John B A G, Spits, Hergen, van der Burg, Sjoerd H, Schumacher, Ton N M
Published in Nature medicine (06.10.2016)
Published in Nature medicine (06.10.2016)
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