In-Depth Study of Tripeptide-Based α-Ketoheterocycles as Inhibitors of Thrombin. Effective Utilization of the S1‘ Subsite and Its Implications to Structure-Based Drug Design
Costanzo, Michael J, Almond, Harold R, Hecker, Leonard R, Schott, Mary R, Yabut, Stephen C, Zhang, Han-Cheng, Andrade-Gordon, Patricia, Corcoran, Thomas W, Giardino, Edward C, Kauffman, Jack A, Lewis, Joan M, de Garavilla, Lawrence, Haertlein, Barbara J, Maryanoff, Bruce E
Published in Journal of medicinal chemistry (24.03.2005)
Published in Journal of medicinal chemistry (24.03.2005)
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Journal Article
In-Depth Study of Tripeptide-Based α-Ketoheterocycles as Inhibitors of Thrombin. Effective Utilization of the S1‘ Subsite and Its Implications to Structure-Based Drug Design
Costanzo, Michael J, Almond, Harold R, Hecker, Leonard R, Schott, Mary R, Yabut, Stephen C, Zhang, Han-Cheng, Andrade-Gordon, Patricia, Corcoran, Thomas W, Giardino, Edward C, Kauffman, Jack A, Lewis, Joan M, de Garavilla, Lawrence, Haertlein, Barbara J, Maryanoff, Bruce E
Published in Journal of medicinal chemistry (15.11.2007)
Published in Journal of medicinal chemistry (15.11.2007)
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Journal Article
Potent Thrombin Inhibitors That Probe the S1‘ Subsite: Tripeptide Transition State Analogues Based on a Heterocycle-Activated Carbonyl Group
Costanzo, Michael J, Maryanoff, Bruce E, Hecker, Leonard R, Schott, Mary R, Yabut, Stephen C, Zhang, Han-Cheng, Andrade-Gordon, Patricia, Kauffman, Jack A, Lewis, Joan M, Krishnan, Raman, Tulinsky, Alexander
Published in Journal of medicinal chemistry (02.08.1996)
Published in Journal of medicinal chemistry (02.08.1996)
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Orally Active Benzamide Antipsychotic Agents with Affinity for Dopamine D2, Serotonin 5-HT1A, and Adrenergic α1 Receptors
Reitz, Allen B, Baxter, Ellen W, Codd, Ellen E, Davis, Coralie B, Jordan, Alfonzo D, Maryanoff, Bruce E, Maryanoff, Cynthia A, McDonnell, Mark E, Powell, Eugene T, Renzi, Michael J, Schott, Mary R, Scott, Malcolm K, Shank, Richard P, Vaught, Jeffry L
Published in Journal of medicinal chemistry (04.06.1998)
Published in Journal of medicinal chemistry (04.06.1998)
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Journal Article
In-depth study of tripeptide-based alpha-ketoheterocycles as inhibitors of thrombin. Effective utilization of the S-1 ' subsite and its implications to structure-based drug design
Costanzo, MJ, Almond, HR, Hecker, LR, Schott, MR, Yabut, SC, Zhang, HC, Andrade-Gordon, P, Corcoran, TW, Giardino, EC, Kauffman, JA, Lewis, JM, de Garavilla, L, Haertlein, BJ, Maryanoff, BE
Published in Journal of medicinal chemistry (24.03.2005)
Published in Journal of medicinal chemistry (24.03.2005)
Get full text
Journal Article
In-Depth Study of Tripeptide-Based α-Ketoheterocycles as Inhibitors of Thrombin. Effective Utilization of the S 1 ‘ Subsite and Its Implications to Structure-Based Drug Design
Costanzo, Michael J., Almond, Harold R., Hecker, Leonard R., Schott, Mary R., Yabut, Stephen C., Zhang, Han-Cheng, Andrade-Gordon, Patricia, Corcoran, Thomas W., Giardino, Edward C., Kauffman, Jack A., Lewis, Joan M., de Garavilla, Lawrence, Haertlein, Barbara J., Maryanoff, Bruce E.
Published in Journal of medicinal chemistry (15.11.2007)
Published in Journal of medicinal chemistry (15.11.2007)
Get full text
Journal Article
In-depth study of tripeptide-based α-ketoheterocycles as inhibitors of thrombin. Effective utilization of the S1' subsite and its implications to structure-based drug designs
COSTANZO, Michael J, ALMOND, Harold R, LEWIS, Joan M, DE GARAVILLA, Lawrence, HAERTLEIN, Barbara J, MARYANOFF, Bruce E, HECKER, Leonard R, SCHOTT, Mary R, YABUT, Stephen C, ZHANG, Han-Cheng, ANDRADE-GORDON, Patricia, CORCORAN, Thomas W, GIARDINO, Edward C, KAUFFMAN, Jack A
Published in Journal of medicinal chemistry (2005)
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Published in Journal of medicinal chemistry (2005)
Journal Article
Potent thrombin inhibitors that probe the S-1' subsite: Tripeptide transition state analogues based on a heterocycle-activated carbonyl group
Costanzo, MJ, Maryanoff, BE, Hecker, LR, Schott, MR, Yabut, SC, Zhang, HC, AndradeGordon, P, Kauffman, JA, Lewis, JM, Krishnan, R, Tulinsky, A
Published in Journal of medicinal chemistry (02.08.1996)
Published in Journal of medicinal chemistry (02.08.1996)
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Journal Article
Small-Molecule Immunostimulants. Synthesis and Activity of 7,8-Disubstituted Guanosines and Structurally Related Compounds
Reitz, Allen B, Goodman, Michael G, Pope, Barbara L, Argentieri, Dennis C, Bell, Stanley C, Burr, Levelle E, Chourmouzis, Erika, Come, Jon, Goodman, Jacquelyn H
Published in Journal of medicinal chemistry (01.10.1994)
Published in Journal of medicinal chemistry (01.10.1994)
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Journal Article
Orally Active Benzamide Antipsychotic Agents with Affinity for Dopamine D 2 , Serotonin 5-HT 1A , and Adrenergic α 1 Receptors
Reitz, Allen B., Baxter, Ellen W., Codd, Ellen E., Davis, Coralie B., Jordan, Alfonzo D., Maryanoff, Bruce E., Maryanoff, Cynthia A., McDonnell, Mark E., Powell, Eugene T., Renzi, Michael J., Schott, Mary R., Scott, Malcolm K., Shank, Richard P., Vaught, Jeffry L.
Published in Journal of medicinal chemistry (01.06.1998)
Published in Journal of medicinal chemistry (01.06.1998)
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Journal Article
GUANOSINE DERIVATIVES AS IMMUNOSTIMULANTS - DISCOVERY OF LOXORIBINE
CHEN, R, GOODMAN, MG, ARGENTIERI, D, BELL, SC, BURR, LE, COME, J, GOODMAN, JH, KLAUBERT, DH, MARYANOFF, BE, POPE, BL, RAMPULLA, MS, SCHOTT, MR, REITZ, AB
Published in Nucleosides & nucleotides (01.03.1994)
Published in Nucleosides & nucleotides (01.03.1994)
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