Mechanistic Investigations of the Mitochondrial Complex I Inhibitor Rotenone in the Context of Pharmacological and Safety Evaluation
Heinz, Sabrina, Freyberger, Alexius, Lawrenz, Bettina, Schladt, Ludwig, Schmuck, Gabriele, Ellinger-Ziegelbauer, Heidrun
Published in Scientific reports (04.04.2017)
Published in Scientific reports (04.04.2017)
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Emodepside targets SLO-1 channels of Onchocerca ochengi and induces broad anthelmintic effects in a bovine model of onchocerciasis
Bah, Germanus S, Schneckener, Sebastian, Hahnel, Steffen R, Bayang, Nicolas H, Fieseler, Helena, Schmuck, Gabriele M, Krebber, Ralph, Sarr, Anouk, Terjung, Carsten, Ngangyung, Henrietta F, Ekale, David D, Mfopit, Youssouf M, Rufener, Lucien, Graham-Brown, John, Tanya, Vincent N, Glenschek-Sieberth, Martin, Kulke, Daniel, Makepeace, Benjamin L
Published in PLoS pathogens (02.06.2021)
Published in PLoS pathogens (02.06.2021)
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International STakeholder NETwork (ISTNET): creating a developmental neurotoxicity (DNT) testing road map for regulatory purposes
Bal-Price, Anna, Crofton, Kevin M., Leist, Marcel, Allen, Sandra, Arand, Michael, Buetler, Timo, Delrue, Nathalie, FitzGerald, Rex E., Hartung, Thomas, Heinonen, Tuula, Hogberg, Helena, Bennekou, Susanne Hougaard, Lichtensteiger, Walter, Oggier, Daniela, Paparella, Martin, Axelstad, Marta, Piersma, Aldert, Rached, Eva, Schilter, Benoît, Schmuck, Gabriele, Stoppini, Luc, Tongiorgi, Enrico, Tiramani, Manuela, Monnet-Tschudi, Florianne, Wilks, Martin F., Ylikomi, Timo, Fritsche, Ellen
Published in Archives of toxicology (01.02.2015)
Published in Archives of toxicology (01.02.2015)
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Journal Article
Artemisone-A Highly Active Antimalarial Drug of the Artemisinin Class
Haynes, Richard K., Fugmann, Burkhard, Stetter, Jörg, Rieckmann, Karl, Heilmann, Hans-Dietrich, Chan, Ho-Wai, Cheung, Man-Ki, Lam, Wai-Lun, Wong, Ho-Ning, Croft, Simon L., Vivas, Livia, Rattray, Lauren, Stewart, Lindsay, Peters, Wallace, Robinson, Brian L., Edstein, Michael D., Kotecka, Barbara, Kyle, Dennis E., Beckermann, Bernhard, Gerisch, Michael, Radtke, Martin, Schmuck, Gabriele, Steinke, Wolfram, Wollborn, Ute, Schmeer, Karl, Römer, Axel
Published in Angewandte Chemie (International ed.) (20.03.2006)
Published in Angewandte Chemie (International ed.) (20.03.2006)
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Neurotoxic Mode of Action of Artemisinin
SCHMUCK, Gabriele, ROEHRDANZ, Elke, HAYNES, Richard K, KAHL, Regine
Published in Antimicrobial Agents and Chemotherapy (01.03.2002)
Published in Antimicrobial Agents and Chemotherapy (01.03.2002)
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Journal Article
The influence of oxidative stress on catalase and MnSOD gene transcription in astrocytes
Röhrdanz, Elke, Schmuck, Gabriele, Ohler, Sandra, Kahl, Regine
Published in Brain research (04.05.2001)
Published in Brain research (04.05.2001)
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Journal Article
Consensus statement on the need for innovation, transition and implementation of developmental neurotoxicity (DNT) testing for regulatory purposes
Fritsche, Ellen, Grandjean, Philippe, Crofton, Kevin M., Aschner, Michael, Goldberg, Alan, Heinonen, Tuula, Hessel, Ellen V.S., Hogberg, Helena T., Bennekou, Susanne Hougaard, Lein, Pamela J., Leist, Marcel, Mundy, William R., Paparella, Martin, Piersma, Aldert H., Sachana, Magdalini, Schmuck, Gabriele, Solecki, Roland, Terron, Andrea, Monnet-Tschudi, Florianne, Wilks, Martin F., Witters, Hilda, Zurich, Marie-Gabrielle, Bal-Price, Anna
Published in Toxicology and applied pharmacology (01.09.2018)
Published in Toxicology and applied pharmacology (01.09.2018)
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Assessment of DNA double-strand breaks and gamma H2AX induced by the topoisomerase II poisons etoposide and mitoxantrone
Smart, D J, Halicka, H D, Schmuck, G, Traganos, F, Darzynkiewicz, Z, Williams, G M
Published in Mutation Research-Fundamental and Molecular Mechanisms of Mutagenesis (10.05.2008)
Published in Mutation Research-Fundamental and Molecular Mechanisms of Mutagenesis (10.05.2008)
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Relationship of cellular topoisomerase IIα inhibition to cytotoxicity and published genotoxicity of fluoroquinolone antibiotics in V79 cells
Williams, Gary M., Brunnemann, Klaus D., Smart, Daniel J., Molina, David, Jeffrey, Alan M., Duan, Jian-Dong, Krebsfaenger, Niels, Kampkoetter, Andreas, Schmuck, Gabriele
Published in Chemico-biological interactions (25.04.2013)
Published in Chemico-biological interactions (25.04.2013)
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Journal Article
Relationship of cellular topoisomerase III- inhibition to cytotoxicity and published genotoxicity of fluoroquinolone antibiotics in V79 cells
Williams, Gary, Brunnemann, Klaus, Smart, Daniel, Molina, David, Jeffrey, Alan, Duan, Jian-Dong, Krebsfaenger, Niels, Kampkoetter, Andreas, Schmuck, Gabriele
Published in Chemico-biological interactions (01.04.2013)
Published in Chemico-biological interactions (01.04.2013)
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Journal Article
Cyclophosphamide and etoposide canine studies demonstrate the cross-species potential of the flow cytometric peripheral blood micronucleated reticulocyte endpoint
McKeon, Marie, Xu, Yong, Kirkland, David, Schmuck, Gabriele, Krebsfänger, Niels, Avlasevich, Svetlana L., Dertinger, Stephen D.
Published in Mutation research (18.02.2012)
Published in Mutation research (18.02.2012)
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Strategies to replace in vivo acute systemic toxicity testing. The report and recommendations of ECVAM Workshop 50
Gennari, Alessandra, van den Berghe, Christine, Casati, Silvia, Castell, José, Clemedson, Cecilia, Coecke, Sandra, Colombo, Alessandra, Curren, Rodger, Dal Negro, Gianni, Goldberg, Alan, Gosmore, Catherine, Hartung, Thomas, Langezaal, Ingrid, Lessigiarska, Iglika, Maas, Wilfred, Mangelsdorf, Inge, Parchment, Ralph, Prieto, Pilar, Sintes, Juan Riego, Ryan, Michael, Schmuck, Gabriele, Stitzel, Katherine, Stokes, William, Vericat, Joan-Albert, Gribaldo, Laura
Published in Alternatives to laboratory animals (01.10.2004)
Published in Alternatives to laboratory animals (01.10.2004)
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Improvements in an in-vitro assay for excitotoxicity by measurement of early gene (c-fos mRNA) levels
ROGERS, Annamarie, SCHMUCK, Gabriele, SCHOLZ, Gabriele, GRIFFITHS, Roger, MEREDITH, Clive, SCHOUSBOE, Arne, CAMPIANI, Giuseppe, WILLIAMS, D. Clive
Published in Archives of toxicology (01.03.2005)
Published in Archives of toxicology (01.03.2005)
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Journal Article
Changes in antioxidant enzyme expression in response to hydrogen peroxide in rat astroglial cells
RÖHRDANZ, Elke, SCHMUCK, Gabriele, OHLER, Sandra, TRAN-THI, Quynh-Hoa, KAHL, Regine
Published in Archives of toxicology (01.05.2001)
Published in Archives of toxicology (01.05.2001)
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