1,4-Diaryl-2-oxo-1,2-dihydro-quinoline-3-carboxylic acids as endothelin receptor antagonists
Mederski, Werner W.K.R., Osswald, Mathias, Dorsch, Dieter, Christadler, Maria, Schmitges, Claus-Jochen, Wilm, Claudia
Published in Bioorganic & medicinal chemistry letters (22.07.1997)
Published in Bioorganic & medicinal chemistry letters (22.07.1997)
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3. Endothelin antagonists: discovery of EMD 122946, a highly potent and orally active ET A selective antagonist
Mederski, Werner W.K.R., Dorsch, Dieter, Osswald, Mathias, Anzali, Soheila, Christadler, Maria, Schmitges, Claus-Jochen, Schelling, Pierre, Wilm, Claudia, Fluck, Markus
Published in Bioorganic & medicinal chemistry letters (07.07.1998)
Published in Bioorganic & medicinal chemistry letters (07.07.1998)
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Journal Article
Pyridazinones with a pendant acylsulfonamide moiety as endothelin receptor antagonists
Dorsch, Dieter, Mederski, Werner W.K.R., Osswald, Mathias, Devant, Ralf M., Schmitges, Claus-Jochen, Christadler, Maria, Wilm, Claudia
Published in Bioorganic & medicinal chemistry letters (04.02.1997)
Published in Bioorganic & medicinal chemistry letters (04.02.1997)
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Benzofuro[3,2-b]pyridines as mixed [formula omitted] and selective ET B endothelin receptor antagonists
Mederski, Werner W.K.R., Osswald, Mathias, Dorsch, Dieter, Christadler, Maria, Schmitges, Claus-Jochen, Wilm, Claudia
Published in Bioorganic & medicinal chemistry letters (1999)
Published in Bioorganic & medicinal chemistry letters (1999)
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2.Endothelin antagonists: Evaluation of 2,1,3-benzothiadiazole as a methylendioxyphenyl bioisoster
Mederski, Werner W.K.R, Osswald, Mathias, Dorsch, Dieter, Anzali, Soheila, Christadler, Maria, Schmitges, Claus-Jochen, Wilm, Claudia
Published in Bioorganic & medicinal chemistry letters (06.01.1998)
Published in Bioorganic & medicinal chemistry letters (06.01.1998)
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Journal Article
3. endothelin antagonists : Discovery of EMD 122946, a highly potent and orally active ETA selective antagonist
MEDERSKI, W. W. K. R, DORSCH, D, OSSWALD, M, ANZALI, S, CHRISTADLER, M, SCHMITGES, C.-J, SCHELLING, P, WILM, C, FLUCK, M
Published in Bioorganic & medicinal chemistry letters (07.07.1998)
Published in Bioorganic & medicinal chemistry letters (07.07.1998)
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Substrate analog renin inhibitors containing replacements of histidine in P2 or isosteres of the amide bond between P3 and P2 sites
Raddatz, Peter, Jonczyk, Alfred, Minck, Klaus Otto, Schmitges, Claus Jochen, Sombroek, Jan
Published in Journal of medicinal chemistry (01.11.1991)
Published in Journal of medicinal chemistry (01.11.1991)
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Journal Article
BENZOTHIA(OXA)DIAZOL DERIVATIVES AND THEIR USE AS ENDOTHELIN-RECEPTOR ANTAGONISTS
OSSWALD MATHIAS, MEDERSKI WERNER DR, WILM CLAUDIA, SCHMITGES CLAUS JOCHEN, CHRISTADLER MARIA, DORSCH DIETER
Year of Publication 30.07.2001
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Year of Publication 30.07.2001
Patent
Benzothia(oxa)diazol derivatives and their use as endothelin-receptor antagonists
WERNER MEDERSKI, CLAUS JOCHEN SCHMITGES, CLAUDIA WILM, MARIA CHRISTADLER, DIETER DORSCH, MATHIAS OSSWALD
Year of Publication 10.05.2001
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Year of Publication 10.05.2001
Patent
Benzothia(oxa)diazol derivatives and their use as endothelin-receptor antagonists
OSSWALD MATHIAS, MEDERSKI WERNER, WILM CLAUDIA, SCHMITGES CLAUS JOCHEN, DORSCH DIETER, CHRISTADLER MARIA
Year of Publication 06.03.2001
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Year of Publication 06.03.2001
Patent