Autoimmunity and primary immunodeficiency: two sides of the same coin?
Schmidt, Reinhold E., Grimbacher, Bodo, Witte, Torsten
Published in Nature reviews. Rheumatology (01.01.2018)
Published in Nature reviews. Rheumatology (01.01.2018)
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Serum neurofilament light levels in normal aging and their association with morphologic brain changes
Khalil, Michael, Pirpamer, Lukas, Hofer, Edith, Voortman, Margarete M., Barro, Christian, Leppert, David, Benkert, Pascal, Ropele, Stefan, Enzinger, Christian, Fazekas, Franz, Schmidt, Reinhold, Kuhle, Jens
Published in Nature communications (10.02.2020)
Published in Nature communications (10.02.2020)
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Longitudinal change of small-vessel disease-related brain abnormalities
Schmidt, Reinhold, Seiler, Stephan, Loitfelder, Marisa
Published in Journal of cerebral blood flow and metabolism (01.01.2016)
Published in Journal of cerebral blood flow and metabolism (01.01.2016)
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Journal Article
CD161+ MAIT cells are severely reduced in peripheral blood and lymph nodes of HIV-infected individuals independently of disease progression
Eberhard, Johanna Maria, Hartjen, Philip, Kummer, Silke, Schmidt, Reinhold E, Bockhorn, Maximilian, Lehmann, Clara, Balagopal, Ashwin, Hauber, Joachim, van Lunzen, Jan, Schulze zur Wiesch, Julian
Published in PloS one (04.11.2014)
Published in PloS one (04.11.2014)
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The adaptor ASC has extracellular and 'prionoid' activities that propagate inflammation
Franklin, Bernardo S, Bossaller, Lukas, De Nardo, Dominic, Ratter, Jacqueline M, Stutz, Andrea, Engels, Gudrun, Brenker, Christoph, Nordhoff, Mark, Mirandola, Sandra R, Al-Amoudi, Ashraf, Mangan, Matthew S, Zimmer, Sebastian, Monks, Brian G, Fricke, Martin, Schmidt, Reinhold E, Espevik, Terje, Jones, Bernadette, Jarnicki, Andrew G, Hansbro, Philip M, Busto, Patricia, Marshak-Rothstein, Ann, Hornemann, Simone, Aguzzi, Adriano, Kastenmüller, Wolfgang, Latz, Eicke
Published in Nature immunology (01.08.2014)
Published in Nature immunology (01.08.2014)
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Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function
Hagenaars, Saskia P., Liewald, David C. M., Ahola-Olli, Ari V., Barnes, Catriona L. K., Bertram, Lars, Bis, Joshua C., Burdick, Katherine E., Christoforou, Andrea, Espeseth, Thomas, Giakoumaki, Stella, Giddaluru, Sudheer, Gustavson, Daniel E., Lahti, Jari, Leber, Markus, Melle, Ingrid, Oldmeadow, Christopher, Reynolds, Chandra A., Scholz, Markus, Smith, Jennifer A., Smith, Albert V., Thalamuthu, Anbupalam, Trompet, Stella, van der Lee, Sven J., Ware, Erin B., Yang, Jingyun, Ames, David, Armstrong, Nicola J., Assareh, Amelia A., Böhmer, Anne C., Campbell, Harry, Cannon, Tyrone D., Corley, Janie, Cox, Simon R., Dale, Anders M., Dick, Danielle, Evangelou, Evangelos, Faul, Jessica D., Ford, Ian, Gao, He, Giegling, Ina, Gillespie, Nathan A., Gordon, Scott D., Gottesman, Rebecca F., Griswold, Michael E., Hatzimanolis, Alex, Heiss, Gerardo, Joshi, Peter K., Kähönen, Mika, Kleineidam, Luca, Kochan, Nicole A., Le Hellard, Stephanie, Lee, Teresa, Lill, Christina M., Longstreth, Will T., Lopez, Oscar L., Loukola, Anu, Lyytikäinen, Leo-Pekka, Martin, Nicholas G., Murray, Alison D., Need, Anna C., Ollier, William, Polasek, Ozren, Riedel-Heller, Steffi G., Rose, Richard J., Rovio, Suvi P., Schmid, Matthias, Scott, Rodney J., Scult, Matthew A., Simino, Jeannette, Straub, Richard E., Tzoulaki, Ioanna, Uitterlinden, André, Vitart, Veronique, Wagner, Michael, Weinhold, Leonie, Wen, K. Hoyan, Adams, Hieab H. H., Arking, Dan E., Chiba-Falek, Ornit, Debette, Stéphanie, Donohoe, Gary, Elliott, Paul, Gill, Michael, Hägg, Sara, Hansell, Narelle K., Vuoksimaa, Eero, Pendleton, Neil, Porteous, David J., Rudan, Igor, Dan Rujescu, Schmidt, Reinhold, Schofield, Peter W., Steen, Vidar M., Van Duijn, Cornelia M., Villringer, Arno, Weinberger, Daniel R., McIntosh, Andrew M., Gale, Catharine R., Mosley, Thomas H., Lencz, Todd
Published in Nature communications (29.05.2018)
Published in Nature communications (29.05.2018)
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Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels
Li, Yong, Wuttke, Matthias, Kirsten, Holger, Qiu, Chengxiang, Gorski, Mathias, Giri, Ayush, Li, Man, Noce, Damia, van der Most, Peter J., Horn, Katrin, Xu, Yizhe, Fuchsberger, Christian, Baptista, Daniela, Brumat, Marco, Campana, Eric, Campbell, Archie, Campbell, Harry, Carroll, Robert J., Catamo, Eulalia, Ciullo, Marina, Concas, Maria Pina, Coresh, Josef, De Grandi, Alessandro, Dittrich, Katalin, Eckardt, Kai-Uwe, Endlich, Karlhans, Evans, Michele K., Gieger, Christian, Gudbjartsson, Daniel F., Hicks, Andrew A., Hofer, Edith, Huang, Wei, Hutri-Kähönen, Nina, Hwang, Shih-Jen, Ikram, M. Arfan, Jakobsdottir, Johanna, Jonsson, Helgi, Joshi, Peter K., Josyula, Navya Shilpa, Jung, Bettina, Kähönen, Mika, Kamatani, Yoichiro, Kanai, Masahiro, Kooner, Jaspal S., Körner, Antje, Kovacs, Peter, Krämer, Bernhard K., Kronenberg, Florian, Kubo, Michiaki, Kühnel, Brigitte, Lange, Leslie A., Loeffler, Markus, Loos, Ruth J. F., Lyytikäinen, Leo-Pekka, Matsuda, Koichi, Meitinger, Thomas, Mishra, Pashupati P., Montgomery, Grant W., Müller-Nurasyid, Martina, Nadkarni, Girish N., Nolte, Ilja M., Noordam, Raymond, Perls, Thomas, Pirastu, Mario, Pistis, Giorgio, Ponte, Belen, Poulain, Tanja, Rabelink, Ton J., Rettig, Rainer, Rheinberger, Myriam, Rice, Kenneth M., Rudan, Igor, Rueedi, Rico, Ryan, Kathleen A., Saba, Yasaman, Shaffer, Christian M., Smith, Albert V., Stumvoll, Michael, Thiery, Joachim, Thio, Chris H. L., Thorsteinsdottir, Unnur, Uitterlinden, André G., Völker, Uwe, Waldenberger, Melanie, Whitfield, John B., Wilson, James F., Zonderman, Alan B., Wilson, James G., Ho, Kevin, Parsa, Afshin, Psaty, Bruce M., Böger, Carsten A., Butterworth, Adam S., Stefansson, Kari, Heid, Iris M., Hung, Adriana M., Teumer, Alexander, Pattaro, Cristian, Woodward, Owen M., Vitart, Veronique
Published in Nature genetics (01.10.2019)
Published in Nature genetics (01.10.2019)
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Autosomal dominant immune dysregulation syndrome in humans with CTLA4 mutations
Schubert, Desirée, Bode, Claudia, Kenefeck, Rupert, Hou, Tie Zheng, Wing, James B, Kennedy, Alan, Bulashevska, Alla, Petersen, Britt-Sabina, Schäffer, Alejandro A, Grüning, Björn A, Unger, Susanne, Frede, Natalie, Baumann, Ulrich, Witte, Torsten, Schmidt, Reinhold E, Dueckers, Gregor, Niehues, Tim, Seneviratne, Suranjith, Kanariou, Maria, Speckmann, Carsten, Ehl, Stephan, Rensing-Ehl, Anne, Warnatz, Klaus, Rakhmanov, Mirzokhid, Thimme, Robert, Hasselblatt, Peter, Emmerich, Florian, Cathomen, Toni, Backofen, Rolf, Fisch, Paul, Seidl, Maximilian, May, Annette, Schmitt-Graeff, Annette, Ikemizu, Shinji, Salzer, Ulrich, Franke, Andre, Sakaguchi, Shimon, Walker, Lucy S K, Sansom, David M, Grimbacher, Bodo
Published in Nature medicine (01.12.2014)
Published in Nature medicine (01.12.2014)
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Dysbiosis, gut barrier dysfunction and inflammation in dementia: a pilot study
Stadlbauer, Vanessa, Engertsberger, Lara, Komarova, Irina, Feldbacher, Nicole, Leber, Bettina, Pichler, Gerald, Fink, Nicole, Scarpatetti, Monika, Schippinger, Walter, Schmidt, Reinhold, Horvath, Angela
Published in BMC geriatrics (20.07.2020)
Published in BMC geriatrics (20.07.2020)
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A Novel Imaging Marker for Small Vessel Disease Based on Skeletonization of White Matter Tracts and Diffusion Histograms
Baykara, Ebru, Gesierich, Benno, Adam, Ruth, Tuladhar, Anil Man, Biesbroek, J. Matthijs, Koek, Huiberdina L., Ropele, Stefan, Jouvent, Eric, Chabriat, Hugues, Ertl-Wagner, Birgit, Ewers, Michael, Schmidt, Reinhold, de Leeuw, Frank-Erik, Biessels, Geert Jan, Dichgans, Martin, Duering, Marco
Published in Annals of neurology (01.10.2016)
Published in Annals of neurology (01.10.2016)
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Quantitative Susceptibility Mapping in Parkinson's Disease
Langkammer, Christian, Pirpamer, Lukas, Seiler, Stephan, Deistung, Andreas, Schweser, Ferdinand, Franthal, Sebastian, Homayoon, Nina, Katschnig-Winter, Petra, Koegl-Wallner, Mariella, Pendl, Tamara, Stoegerer, Eva Maria, Wenzel, Karoline, Fazekas, Franz, Ropele, Stefan, Reichenbach, Jürgen Rainer, Schmidt, Reinhold, Schwingenschuh, Petra
Published in PloS one (06.09.2016)
Published in PloS one (06.09.2016)
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Cerebral small vessel disease genomics and its implications across the lifespan
Sargurupremraj, Muralidharan, Suzuki, Hideaki, Jian, Xueqiu, Sarnowski, Chloé, Evans, Tavia E., Eiriksdottir, Gudny, Sakaue, Saori, Terzikhan, Natalie, Zhao, Wei, Armstrong, Nicola J., Yanek, Lisa R., Kumar, Rajan B., van den Akker, Erik B., McWhirter, Rebekah E., Trompet, Stella, Mishra, Aniket, Saba, Yasaman, Satizabal, Claudia L., Beaudet, Gregory, Petit, Laurent, Tsuchida, Ami, Schilling, Sabrina, Sigurdsson, Sigurdur, Lewis, Cora E., Lopez, Oscar L., Smith, Jennifer A., Valdés Hernández, Maria C., van der Grond, Jeroen, Wright, Margaret J., Knol, Maria J., Thomson, Russell J., Le Grand, Quentin, Duperron, Marie-Gabrielle, Smith, Albert V., Schreiner, Pamela J., Evans, Denis A., Rotter, Jerome I., Beiser, Alexa S., Maniega, Susana Muñoz, Beekman, Marian, Trollor, Julian, Stott, David J., Vernooij, Meike W., Wittfeld, Katharina, Niessen, Wiro J., Soumaré, Aicha, Sidney, Stephen, Turner, Stephen T., Davies, Gail, Thalamuthu, Anbupalam, Völker, Uwe, van Buchem, Mark A., Dupuis, Josée, Bastin, Mark E., Teumer, Alexander, Amouyel, Philippe, Kwok, John B., Bülow, Robin, Deary, Ian J., Schofield, Peter R., Brodaty, Henry, Jiang, Jiyang, Tabara, Yasuharu, Setoh, Kazuya, Miyamoto, Susumu, Yoshida, Kazumichi, Nagata, Manabu, Matsuda, Fumihiko, Psaty, Bruce M., Bennett, David A., De Jager, Philip L., Mosley, Thomas H., Sachdev, Perminder S., Schmidt, Reinhold, Evangelou, Evangelos, Trégouët, David-Alexandre, Ikram, Mohammad A., DeCarli, Charles, Srikanth, Velandai K., Jukema, J. Wouter, Slagboom, Eline P., Kardia, Sharon L. R., Okada, Yukinori, Mazoyer, Bernard, Wardlaw, Joanna M., Nyquist, Paul A., Mather, Karen A., Grabe, Hans J., Schmidt, Helena, Van Duijn, Cornelia M., Gudnason, Vilmundur, Longstreth, William T., Launer, Lenore J., Lathrop, Mark, Seshadri, Sudha, Tzourio, Christophe, Adams, Hieab H., Matthews, Paul M., Fornage, Myriam, Debette, Stéphanie
Published in Nature communications (08.12.2020)
Published in Nature communications (08.12.2020)
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Safety and immunogenicity of the tau vaccine AADvac1 in patients with Alzheimer's disease: a randomised, double-blind, placebo-controlled, phase 1 trial
Novak, Petr, Dr, Schmidt, Reinhold, Prof, Kontsekova, Eva, Prof, Zilka, Norbert, PhD, Kovacech, Branislav, PhD, Skrabana, Rostislav, PhD, Vince-Kazmerova, Zuzana, PhD, Katina, Stanislav, PhD, Fialova, Lubica, PhD, Prcina, Michal, PhD, Parrak, Vojtech, MD, Dal-Bianco, Peter, MD, Brunner, Martin, MD, Staffen, Wolfgang, MD, Rainer, Michael, MD, Ondrus, Matej, MD, Ropele, Stefan, Ing, Smisek, Miroslav, MD, Sivak, Roman, Ing, Winblad, Bengt, Prof, Novak, Michal, Prof
Published in Lancet neurology (01.02.2017)
Published in Lancet neurology (01.02.2017)
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Ocrelizumab Depletes CD20⁺ T Cells in Multiple Sclerosis Patients
Gingele, Stefan, Jacobus, Thais Langer, Konen, Franz Felix, Hümmert, Martin W, Sühs, Kurt-Wolfram, Schwenkenbecher, Philipp, Ahlbrecht, Jonas, Möhn, Nora, Müschen, Lars H, Bönig, Lena, Alvermann, Sascha, Schmidt, Reinhold E, Stangel, Martin, Jacobs, Roland, Skripuletz, Thomas
Published in Cells (Basel, Switzerland) (28.12.2018)
Published in Cells (Basel, Switzerland) (28.12.2018)
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Global Burden of Small Vessel Disease–Related Brain Changes on MRI Predicts Cognitive and Functional Decline
Jokinen, Hanna, Koikkalainen, Juha, Laakso, Hanna M., Melkas, Susanna, Nieminen, Tuomas, Brander, Antti, Korvenoja, Antti, Rueckert, Daniel, Barkhof, Frederik, Scheltens, Philip, Schmidt, Reinhold, Fazekas, Franz, Madureira, Sofia, Verdelho, Ana, Wallin, Anders, Wahlund, Lars-Olof, Waldemar, Gunhild, Chabriat, Hugues, Hennerici, Michael, O’Brien, John, Inzitari, Domenico, Lötjönen, Jyrki, Pantoni, Leonardo, Erkinjuntti, Timo
Published in Stroke (1970) (01.01.2020)
Published in Stroke (1970) (01.01.2020)
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High frequency of variants in genes associated with primary immunodeficiencies in patients with rheumatic diseases with secondary hypogammaglobulinaemia
Sogkas, Georgios, Dubrowinskaja, Natalia, Adriawan, Ignatius Ryan, Anim, Manfred, Witte, Torsten, Schmidt, Reinhold E, Atschekzei, Faranaz
Published in Annals of the rheumatic diseases (01.03.2021)
Published in Annals of the rheumatic diseases (01.03.2021)
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Cutting Edge: Protein Arginine Deiminase 2 and 4 Regulate NLRP3 Inflammasome-Dependent IL-1β Maturation and ASC Speck Formation in Macrophages
Mishra, Neha, Schwerdtner, Lidja, Sams, Kelly, Mondal, Santanu, Ahmad, Fareed, Schmidt, Reinhold E, Coonrod, Scott A, Thompson, Paul R, Lerch, Markus M, Bossaller, Lukas
Published in The Journal of immunology (1950) (15.08.2019)
Published in The Journal of immunology (1950) (15.08.2019)
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B cell depletion impairs vaccination-induced CD8+ T cell responses in a type I interferon-dependent manner
Graalmann, Theresa, Borst, Katharina, Manchanda, Himanshu, Vaas, Lea, Bruhn, Matthias, Graalmann, Lukas, Koster, Mario, Verboom, Murielle, Hallensleben, Michael, Guzmán, Carlos Alberto, Sutter, Gerd, Schmidt, Reinhold E, Witte, Torsten, Kalinke, Ulrich
Published in Annals of the rheumatic diseases (01.12.2021)
Published in Annals of the rheumatic diseases (01.12.2021)
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