Mechanistic Characterization of the Pharmacological Profile of HS-731, a Peripherally Acting Opioid Analgesic, at the µ-, δ-, κ-Opioid and Nociceptin Receptors
Puls, Kristina, Schmidhammer, Helmut, Wolber, Gerhard, Spetea, Mariana
Published in Molecules (Basel, Switzerland) (28.01.2022)
Published in Molecules (Basel, Switzerland) (28.01.2022)
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In vitro and in vivo Pharmacological Activities of 14- O -Phenylpropyloxymorphone, a Potent Mixed Mu/Delta/Kappa-Opioid Receptor Agonist With Reduced Constipation in Mice
Lattanzi, Roberta, Rief, Silvia, Schmidhammer, Helmut, Negri, Lucia, Spetea, Mariana
Published in Frontiers in pharmacology (31.08.2018)
Published in Frontiers in pharmacology (31.08.2018)
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On the Role of Peripheral Sensory and Gut Mu Opioid Receptors: Peripheral Analgesia and Tolerance
Fürst, Susanna, Zádori, Zoltán S, Zádor, Ferenc, Király, Kornél, Balogh, Mihály, László, Szilvia B, Hutka, Barbara, Mohammadzadeh, Amir, Calabrese, Chiara, Galambos, Anna Rita, Riba, Pál, Romualdi, Patrizia, Benyhe, Sándor, Timár, Júlia, Schmidhammer, Helmut, Spetea, Mariana, Al-Khrasani, Mahmoud
Published in Molecules (Basel, Switzerland) (26.05.2020)
Published in Molecules (Basel, Switzerland) (26.05.2020)
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Pharmacological investigations of N-substituent variation in morphine and oxymorphone: opioid receptor binding, signaling and antinociceptive activity
Ben Haddou, Tanila, Béni, Szabolcs, Hosztafi, Sándor, Malfacini, Davide, Calo, Girolamo, Schmidhammer, Helmut, Spetea, Mariana
Published in PloS one (11.06.2014)
Published in PloS one (11.06.2014)
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Current κ opioid receptor ligands and discovery of a new molecular scaffold as a κ opioid receptor antagonist using pharmacophore-based virtual screening
Spetea, Mariana, Asim, Muhammad Faheem, Noha, Stefan, Wolber, Gerhard, Schmidhammer, Helmut
Published in Current pharmaceutical design (2013)
Published in Current pharmaceutical design (2013)
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Functionalization of the carbonyl group in position 6 of morphinan-6-ones. Development of novel 6-amino and 6-guanidino substituted 14-alkoxymorphinans
Schmidhammer, Helmut, Spetea, Mariana, Windisch, Petra, Schütz, Johannes, Riba, Pal, Al-Khrasani, Mahmoud, Furst, Susanna
Published in Current pharmaceutical design (2013)
Published in Current pharmaceutical design (2013)
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Modulation of basal and stress-induced amygdaloid substance P release by the potent and selective NK1 receptor antagonist L-822429
Singewald, Nicolas, Chicchi, Gary G, Thurner, Clemens C, Tsao, Kwei-Lan, Spetea, Mariana, Schmidhammer, Helmut, Sreepathi, Hari Kishore, Ferraguti, Francesco, Singewald, Georg M, Ebner, Karl
Published in Journal of neurochemistry (01.09.2008)
Published in Journal of neurochemistry (01.09.2008)
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Lack of regulatory changes of µ-opioid receptors by 14-methoxymetopon treatment in rat brain. Further evidence for functional selectivity
Cinar, Resat, Kékesi, Orsolya, Birkás, Erika, Fábián, Gabriella, Schmidhammer, Helmut, Szücs, Mária
Published in Current pharmaceutical design (01.12.2013)
Published in Current pharmaceutical design (01.12.2013)
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Exploring Pharmacological Activities and Signaling of Morphinans Substituted in Position 6 as Potent Agonists Interacting with the μ Opioid Receptor
Haddou, Tanila Ben, Malfacini, Davide, Calo, Girolamo, Aceto, Mario D, Harris, Louis S, Traynor, John R, Coop, Andrew, Schmidhammer, Helmut, Spetea, Mariana
Published in Molecular pain (24.07.2014)
Published in Molecular pain (24.07.2014)
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Peripheral versus Central Antinociceptive Actions of 6-Amino Acid-Substituted Derivatives of 14-O-Methyloxymorphone in Acute and Inflammatory Pain in the Rat
Fürst, Susanna, Riba, Pal, Friedmann, Tamas, Tímar, Julia, Al-Khrasani, Mahmoud, Obara, Ilona, Makuch, Wioletta, Spetea, Mariana, Schütz, Johannes, Przewlocki, Ryszard, Przewlocka, Barbara, Schmidhammer, Helmut
Published in The Journal of pharmacology and experimental therapeutics (01.02.2005)
Published in The Journal of pharmacology and experimental therapeutics (01.02.2005)
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