A bicistronic vector with destabilized mRNA secondary structure yields scalable higher titer expression of human neurturin in E. coli
Roy, Varnika, Roth, Robert, Berge, Mark, Chitta, Rajesh, Vajrala, Sucheta, Kuntumalla, Srilatha, E. Schmelzer, Albert, Schoner, Ron
Published in Biotechnology and bioengineering (01.08.2017)
Published in Biotechnology and bioengineering (01.08.2017)
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Developing an Anion Exchange Chromatography Assay for Determining Empty and Full Capsid Contents in AAV6.2
Wang, Chunlei, Mulagapati, Sri Hari Raju, Chen, Zhongying, Du, Jing, Zhao, Xiaohui, Xi, Guoling, Chen, Liyan, Linke, Thomas, Gao, Cuihua, Schmelzer, Albert E., Liu, Dengfeng
Published in Molecular therapy. Methods & clinical development (13.12.2019)
Published in Molecular therapy. Methods & clinical development (13.12.2019)
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Journal Article
Development of a CHO-Based Cell-Free Platform for Synthesis of Active Monoclonal Antibodies
Martin, Rey W, Majewska, Natalia I, Chen, Cindy X, Albanetti, Thomas E, Jimenez, Rod Brian C, Schmelzer, Albert E, Jewett, Michael C, Roy, Varnika
Published in ACS synthetic biology (21.07.2017)
Published in ACS synthetic biology (21.07.2017)
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Chemically Defined, High-Density Insect Cell-Based Expression System for Scalable AAV Vector Production
Kurasawa, James H., Park, Andrew, Sowers, Carrie R., Halpin, Rebecca A., Tovchigrechko, Andrey, Dobson, Claire L., Schmelzer, Albert E., Gao, Changshou, Wilson, Susan D., Ikeda, Yasuhiro
Published in Molecular therapy. Methods & clinical development (11.12.2020)
Published in Molecular therapy. Methods & clinical development (11.12.2020)
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Journal Article
Production and characterization of active recombinant human factor II with consistent sialylation
Lee, Jeong H., Reier, Jason, Heffner, Kelley M., Barton, Christopher, Spencer, David, Schmelzer, Albert E., Venkat, Raghavan
Published in Biotechnology and bioengineering (01.09.2017)
Published in Biotechnology and bioengineering (01.09.2017)
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Process economics evaluation and optimization of adeno‐associated virus downstream processing
Lyle, Annabel, Stamatis, Christos, Linke, Thomas, Hulley, Martyn, Schmelzer, Albert, Turner, Richard, Farid, Suzanne S.
Published in Biotechnology and bioengineering (01.08.2024)
Published in Biotechnology and bioengineering (01.08.2024)
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Journal Article
2-Iminopyrrolidines as Potent and Selective Inhibitors of Human Inducible Nitric Oxide Synthase
Hagen, Timothy J, Bergmanis, Arija A, Kramer, Steven W, Fok, Kam F, Schmelzer, Albert E, Pitzele, Barnett S, Swenton, Lydia, Jerome, Gina M, Kornmeier, Christine M, Moore, William M, Branson, Linda F, Connor, Jane R, Manning, Pamela T, Currie, Mark G, Hallinan, E. Ann
Published in Journal of medicinal chemistry (10.09.1998)
Published in Journal of medicinal chemistry (10.09.1998)
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Accelerated cell culture process development and characterization for cilgavimab/tixagevimab (AZD7442) for the prevention and treatment of COVID-19
Handlogten, Michael W, Bosley, Stefanie, Dunn, Sarah, Zhu, Jie, Lee-O'Brien, Allison, Li, Lina, Therres, Jamy, Chakrabarti, Lina, Khanal, Bijay, Mowery, Rachel, Arumugam, Subhashini, Klover, Judith, Taleb, Mohammed, Reier, Jason, Hatton, Diane, Schmelzer, Albert
Published in Biotechnology and bioengineering (07.02.2023)
Published in Biotechnology and bioengineering (07.02.2023)
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Journal Article
Liquid-liquid phase separation causes high turbidity and pressure during low pH elution process in Protein A chromatography
Luo, Haibin, Lee, Nacole, Wang, Xiangyang, Li, Yuling, Schmelzer, Albert, Hunter, Alan K., Pabst, Timothy, Wang, William K.
Published in Journal of Chromatography A (10.03.2017)
Published in Journal of Chromatography A (10.03.2017)
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Journal Article
Role of Nucleotide Sugar Pools in the Inhibition of NCAM Polysialylation by Ammonia
Zanghi, James A., Mendoza, Thomas P., Schmelzer, Albert E., Knop, Richard H., Miller, William M.
Published in Biotechnology progress (01.11.1998)
Published in Biotechnology progress (01.11.1998)
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