Search Results - "SCHILS Didier" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Establishing Best Practice for the Application and Support of Solubility Purge Factors

Establishing Best Practice for the Application and Support of Solubility Purge Factors

by Burns, Michael J., Andrews, Ian X., Baumann, Jens-Christoph, Elliott, Eric L., Fennell, Jared W., Kallemeyn, Jeffrey M., Lemaire, Sebastien, Murphy, Natasha S., Palacio, Magali, Raw, Steven A., Roberts, Alastair J., Moura Rocha, Nayrton Flávio, Schils, Didier, Oestrich, Rolf Schulte, Shannon-Little, Andrew L., Stevenson, Neil, Talavera, Pere, Teasdale, Andrew, Urquhart, Michael W., Waechter, Fernanda
Published in Organic process research & development (20.10.2023)

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Journal Article

(5S)-사이클로프로필-5-[3-[(3S)-4--3-메틸-피페라진-1-일]-3-옥소-프로필]이미다졸리딘-2,4-디온의 고체 형태

(5S)-사이클로프로필-5-[3-[(3S)-4--3-메틸-피페라진-1-일]-3-옥소-프로필]이미다졸리딘-2,4-디온의 고체 형태

by LYNCH MICHAEL ANTHONY, CORVELEYN SAM BOB, DULOS GRADUS JOHANNES, LEPINE RENAUD HENRI MARCEL, SCHILS DIDIER PHILIPPE ROBERT, LEBLANC NICOLAS VALENTIN
Year of Publication 21.08.2023

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Patent

New Semi-Automated Computer-Based System for Assessing the Purge of Mutagenic Impurities

New Semi-Automated Computer-Based System for Assessing the Purge of Mutagenic Impurities

by Burns, Michael J, Ott, Martin A, Teasdale, Andrew, Stalford, Susanne A, Antonucci, Vincent, Baumann, Jens-Christoph, Brown, Roland, Covey-Crump, Elizabeth M, Elder, David, Elliott, Eric, Fennell, Jared W, Gallou, Fabrice, Ide, Nathan D, Itoh, Tetsuji, Jordine, Guido, Kallemeyn, Jeffrey M, Lauwers, Dirk, Looker, Adam R, Lovelle, Lucie E, Molzahn, Robert, Schils, Didier, Schulte Oestrich, Rolf, Sluggett, Gregory W, Stevenson, Neil, Talavera, Pere, Urquhart, Michael W, Varie, David L, Welch, Dennie S
Published in Organic process research & development (15.11.2019)

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Journal Article

N-Thiazolylamide-based free fatty-acid 2 receptor agonists: Discovery, lead optimization and demonstration of off-target effect in a diabetes model

N-Thiazolylamide-based free fatty-acid 2 receptor agonists: Discovery, lead optimization and demonstration of off-target effect in a diabetes model

by Hoveyda, Hamid R., Fraser, Graeme L., Zoute, Ludivine, Dutheuil, Guillaume, Schils, Didier, Brantis, Cyrille, Lapin, Alexey, Parcq, Julien, Guitard, Sandra, Lenoir, François, Bousmaqui, Mohamed El, Rorive, Sarah, Hospied, Sandrine, Blanc, Sébastien, Bernard, Jérôme, Ooms, Frédéric, McNelis, Joanne C., Olefsky, Jerrold M.
Published in Bioorganic & medicinal chemistry (01.10.2018)

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A consortium-driven framework to guide the implementation of ICH M7 Option 4 control strategies

A consortium-driven framework to guide the implementation of ICH M7 Option 4 control strategies

by Barber, Chris, Antonucci, Vincent, Baumann, Jens-Christoph, Brown, Roland, Covey-Crump, Elizabeth, Elder, David, Elliott, Eric, Fennell, Jared W., Gallou, Fabrice, Ide, Nathan D., Jordine, Guido, Kallemeyn, Jeffrey M., Lauwers, Dirk, Looker, Adam R., Lovelle, Lucie E., McLaughlin, Mark, Molzahn, Robert, Ott, Martin, Schils, Didier, Oestrich, Rolf Schulte, Stevenson, Neil, Talavera, Pere, Teasdale, Andrew, Urquhart, Michael W., Varie, David L., Welch, Dennie
Published in Regulatory toxicology and pharmacology (01.11.2017)

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Journal Article

Ligandless Heck Coupling between a Halogenated Aniline and Acrylonitrile Catalyzed by Pd/C: Development and Optimization of an Industrial-Scale Heck Process for the Production of a Pharmaceutical Intermediate

Ligandless Heck Coupling between a Halogenated Aniline and Acrylonitrile Catalyzed by Pd/C: Development and Optimization of an Industrial-Scale Heck Process for the Production of a Pharmaceutical Intermediate

by Schils, Didier, Stappers, Fred, Solberghe, Geoffrey, van Heck, Richard, Coppens, Michelle, Van den Heuvel, Dirk, Van der Donck, Peter, Callewaert, Tom, Meeussen, Frank, Bie, Erika De, Eersels, Kristof, Schouteden, Ellen
Published in Organic process research & development (01.05.2008)

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Journal Article

COMPOUNDS, PHARMACEUTICAL COMPOSITION AND METHODS FOR USE IN TREATING INFLAMMATORY DISEASES

COMPOUNDS, PHARMACEUTICAL COMPOSITION AND METHODS FOR USE IN TREATING INFLAMMATORY DISEASES

by ZOUTE LUDIVINE, BERNARD JEROME, PARCQ JULIEN, FRASER GRAEME, SCHILS DIDIER, HOVEYDA HAMID
Year of Publication 06.07.2016

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Patent

PYRROLIDINE OR THIAZOLIDINE CARBOXYLIC ACID DERIVATIVES, PHARMACEUTICAL COMPOSITION AND METHODS FOR USE IN TREATING METABOLIC DISORDERS AS AGONISTS OF G-PROTEIN COUPLED RECEPTOR 43 (GPR43)

PYRROLIDINE OR THIAZOLIDINE CARBOXYLIC ACID DERIVATIVES, PHARMACEUTICAL COMPOSITION AND METHODS FOR USE IN TREATING METABOLIC DISORDERS AS AGONISTS OF G-PROTEIN COUPLED RECEPTOR 43 (GPR43)

by ZOUTE LUDIVINE, PARCQ JULIEN, SCHILS DIDIER, HOVEYDA HAMID
Year of Publication 13.05.2014

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Patent

Utilization of Sequential Palladium-Catalyzed Cross-Coupling Reactions in the Stereospecific Synthesis of Trisubstituted Olefins

Utilization of Sequential Palladium-Catalyzed Cross-Coupling Reactions in the Stereospecific Synthesis of Trisubstituted Olefins

by Houpis, Ioannis N, Schils, Didier, Nettekoven, Ulrike, Schnyder, Anita, Bappert, Erhart, Weerts, Koen, Canters, Martine, Vermeulen, Wim
Published in Organic process research & development (18.09.2009)

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Journal Article

COMPOUNDS, PHARMACEUTICAL COMPOSITION AND METHODS FOR USE IN TREATING METABOLIC DISORDERS

COMPOUNDS, PHARMACEUTICAL COMPOSITION AND METHODS FOR USE IN TREATING METABOLIC DISORDERS

by DUTHEUIL GUILLAUME, ZOUTE LUDIVINE, BERNARD JEROME, BRANTIS CYRILLE EVANGELOS, SCHILS DIDIER, HOVEYDA HAMID
Year of Publication 31.08.2011

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Patent

SOLID FORMS OF (5S)-CYCLOPROPYL-5-[3-[(3S)-4-(3,5-DIFLUOROPHENYL)-3-METHYL-PIPERAZIN-1-YL]-3-OXO-PROPYL]IMIDAZOLIDINE-2,4-DIONE

SOLID FORMS OF (5S)-CYCLOPROPYL-5-[3-[(3S)-4-(3,5-DIFLUOROPHENYL)-3-METHYL-PIPERAZIN-1-YL]-3-OXO-PROPYL]IMIDAZOLIDINE-2,4-DIONE

by CORVELEYN, Sam Bob, DULOS, Gradus Johannes, LYNCH, Michael, LÉPINE, Renaud, SCHILS, Didier, LEBLANC, Nicolas
Year of Publication 03.08.2023

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Patent

SOLID FORMS OF (5S)-CYCLOPROPYL-5-[3-[(3S)-4-(3,5-DIFLUOROPHENYL)-3-METHYL-PIPERAZIN-1-YL]-3-OXO-PROPYL]IMIDAZOLIDINE-2,4-DIONE

SOLID FORMS OF (5S)-CYCLOPROPYL-5-[3-[(3S)-4-(3,5-DIFLUOROPHENYL)-3-METHYL-PIPERAZIN-1-YL]-3-OXO-PROPYL]IMIDAZOLIDINE-2,4-DIONE

by LÉPINE, Renaud Henri Marcel, LEBLANC, Nicolas Valentin, CORVELEYN, Sam Bob, DULOS, Gradus Johannes, SCHILS, Didier Philippe Robert, LYNCH, Michael Anthony
Year of Publication 18.04.2024

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Patent

Substituted pyrrolidines as G-protein coupled receptor 43 agonists

Substituted pyrrolidines as G-protein coupled receptor 43 agonists

by Schils, Didier, Zoute, Ludivine, Hoveyda, Hamid R, Parcq, Julien
Year of Publication 27.07.2021

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Patent

SOLID FORMS OF (5S)-CYCLOPROPYL-5-[3-[(3S)-4-(3,5-DIFLUOROPHENYL)-3-METHYL-PIPERAZIN-1-YL]-3-OXO-PROPYL]IMIDAZOLIDINE-2,4-DIONE

SOLID FORMS OF (5S)-CYCLOPROPYL-5-[3-[(3S)-4-(3,5-DIFLUOROPHENYL)-3-METHYL-PIPERAZIN-1-YL]-3-OXO-PROPYL]IMIDAZOLIDINE-2,4-DIONE

by LÉPINE, Renaud, Henri, Marcel, SCHILS, Didier, Philippe, Robert, CORVELEYN, Sam Bob, DULOS, Gradus Johannes, LYNCH, Michael, Anthony, LEBLANC, Nicolas, Valentin
Year of Publication 25.10.2023

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Patent

Prodrug Modulators of the Cystic Fibrosis Transmembrane Conductance Regulator Protein and Methods of Use

Prodrug Modulators of the Cystic Fibrosis Transmembrane Conductance Regulator Protein and Methods of Use

by Schils, Didier Philippe Robert, Corveleyn, Sam Bob, De Kock, Herman Augustinus, Dufek, Matthew Beau
Year of Publication 08.09.2022

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Patent

SUBSTITUTED PYRROLIDINES AS G-PROTEIN COUPLED RECEPTOR 43 AGONISTS

SUBSTITUTED PYRROLIDINES AS G-PROTEIN COUPLED RECEPTOR 43 AGONISTS

by Schils, Didier, Zoute, Ludivine, Hoveyda, Hamid R, Parcq, Julien
Year of Publication 05.11.2020

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Patent

Substituted pyrrolidines as G-protein coupled receptor 43 agonists

Substituted pyrrolidines as G-protein coupled receptor 43 agonists

by Schils, Didier, Zoute, Ludivine, Hoveyda, Hamid R, Parcq, Julien
Year of Publication 22.09.2020

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Patent

SOLID FORMS OF (5S)-CYCLOPROPYL-5-[3-[(3S)-4-(3,5-DIFLUOROPHENYL)-3-METHYL-PIPERAZIN-1-YL]-3-OXO-PROPYL]IMIDAZOLIDINE-2,4-DIONE

SOLID FORMS OF (5S)-CYCLOPROPYL-5-[3-[(3S)-4-(3,5-DIFLUOROPHENYL)-3-METHYL-PIPERAZIN-1-YL]-3-OXO-PROPYL]IMIDAZOLIDINE-2,4-DIONE

by CORVELEYN, Sam Bob, DULOS, Gradus Johannes, LYNCH, Michael, LÉPINE, Renaud, SCHILS, Didier, LEBLANC, Nicolas
Year of Publication 23.06.2022

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Patent

Prodrug modulators of the cystic fibrosis transmembrane conductance regulator protein and methods of use

Prodrug modulators of the cystic fibrosis transmembrane conductance regulator protein and methods of use

by Schils, Didier Philippe Robert, Corveleyn, Sam Bob, De Kock, Herman Augustinus, Dufek, Matthew Beau
Year of Publication 31.05.2022

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Patent

PYRROLIDINE OR THIAZOLIDINE CARBOXYLIC ACID DERIVATIVES, PHARMACEUTICAL COMPOSITION AND METHODS FOR USE IN TREATING METABOLIC DISORDERS AS AGONISTS OF G-PROTEIN COUPLED RECEPTOR 43 (GPR43)

PYRROLIDINE OR THIAZOLIDINE CARBOXYLIC ACID DERIVATIVES, PHARMACEUTICAL COMPOSITION AND METHODS FOR USE IN TREATING METABOLIC DISORDERS AS AGONISTS OF G-PROTEIN COUPLED RECEPTOR 43 (GPR43)

by Schils, Didier, Zoute, Ludivine, Hoveyda, Hamid R, Parcq, Julien
Year of Publication 14.05.2020

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Patent

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