Improving Viral Protease Inhibitors to Counter Drug Resistance
Kurt Yilmaz, Nese, Swanstrom, Ronald, Schiffer, Celia A
Published in Trends in microbiology (Regular ed.) (01.07.2016)
Published in Trends in microbiology (Regular ed.) (01.07.2016)
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The molecular basis of drug resistance against hepatitis C virus NS3/4A protease inhibitors
Romano, Keith P, Ali, Akbar, Aydin, Cihan, Soumana, Djade, Ozen, Ayşegül, Deveau, Laura M, Silver, Casey, Cao, Hong, Newton, Alicia, Petropoulos, Christos J, Huang, Wei, Schiffer, Celia A
Published in PLoS pathogens (01.07.2012)
Published in PLoS pathogens (01.07.2012)
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Defining the substrate envelope of SARS-CoV-2 main protease to predict and avoid drug resistance
Shaqra, Ala M., Zvornicanin, Sarah N., Huang, Qiu Yu J., Lockbaum, Gordon J., Knapp, Mark, Tandeske, Laura, Bakan, David T., Flynn, Julia, Bolon, Daniel N. A., Moquin, Stephanie, Dovala, Dustin, Kurt Yilmaz, Nese, Schiffer, Celia A.
Published in Nature communications (21.06.2022)
Published in Nature communications (21.06.2022)
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Interactions of APOBEC3s with DNA and RNA
Maiti, Atanu, Hou, Shurong, Schiffer, Celia A, Matsuo, Hiroshi
Published in Current opinion in structural biology (01.04.2021)
Published in Current opinion in structural biology (01.04.2021)
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Crystal Structure of SARS-CoV-2 Main Protease in Complex with the Non-Covalent Inhibitor ML188
Lockbaum, Gordon J, Reyes, Archie C, Lee, Jeong Min, Tilvawala, Ronak, Nalivaika, Ellen A, Ali, Akbar, Kurt Yilmaz, Nese, Thompson, Paul R, Schiffer, Celia A
Published in Viruses (25.01.2021)
Published in Viruses (25.01.2021)
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Crystal structure of APOBEC3A bound to single-stranded DNA reveals structural basis for cytidine deamination and specificity
Kouno, Takahide, Silvas, Tania V., Hilbert, Brendan J., Shandilya, Shivender M. D., Bohn, Markus F., Kelch, Brian A., Royer, William E., Somasundaran, Mohan, Kurt Yilmaz, Nese, Matsuo, Hiroshi, Schiffer, Celia A.
Published in Nature communications (28.04.2017)
Published in Nature communications (28.04.2017)
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Crystal structure of the catalytic domain of HIV-1 restriction factor APOBEC3G in complex with ssDNA
Maiti, Atanu, Myint, Wazo, Kanai, Tapan, Delviks-Frankenberry, Krista, Sierra Rodriguez, Christina, Pathak, Vinay K., Schiffer, Celia A., Matsuo, Hiroshi
Published in Nature communications (25.06.2018)
Published in Nature communications (25.06.2018)
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Drug resistance against HCV NS3/4A inhibitors is defined by the balance of substrate recognition versus inhibitor binding
Romano, Keith P., Ali, Akbar, Royer, William E., Schiffer, Celia A., Coffin, John M.
Published in Proceedings of the National Academy of Sciences - PNAS (07.12.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (07.12.2010)
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The ssDNA Mutator APOBEC3A Is Regulated by Cooperative Dimerization
Bohn, Markus-Frederik, Shandilya, Shivender M D, Silvas, Tania V, Nalivaika, Ellen A, Kouno, Takahide, Kelch, Brian A, Ryder, Sean P, Kurt-Yilmaz, Nese, Somasundaran, Mohan, Schiffer, Celia A
Published in Structure (London) (05.05.2015)
Published in Structure (London) (05.05.2015)
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Influenza virus drug resistance: a time-sampled population genetics perspective
Foll, Matthieu, Poh, Yu-Ping, Renzette, Nicholas, Ferrer-Admetlla, Anna, Bank, Claudia, Shim, Hyunjin, Malaspinas, Anna-Sapfo, Ewing, Gregory, Liu, Ping, Wegmann, Daniel, Caffrey, Daniel R, Zeldovich, Konstantin B, Bolon, Daniel N, Wang, Jennifer P, Kowalik, Timothy F, Schiffer, Celia A, Finberg, Robert W, Jensen, Jeffrey D
Published in PLoS genetics (01.02.2014)
Published in PLoS genetics (01.02.2014)
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Non-canonical pattern recognition of a pathogen-derived metabolite by a nuclear hormone receptor identifies virulent bacteria in C. elegans
Peterson, Nicholas D., Tse, Samantha Y., Huang, Qiuyu Judy, Wani, Khursheed A., Schiffer, Celia A., Pukkila-Worley, Read
Published in Immunity (Cambridge, Mass.) (11.04.2023)
Published in Immunity (Cambridge, Mass.) (11.04.2023)
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Pan-3C Protease Inhibitor Rupintrivir Binds SARS-CoV‑2 Main Protease in a Unique Binding Mode
Lockbaum, Gordon J, Henes, Mina, Lee, Jeong Min, Timm, Jennifer, Nalivaika, Ellen A, Thompson, Paul R, Kurt Yilmaz, Nese, Schiffer, Celia A
Published in Biochemistry (Easton) (05.10.2021)
Published in Biochemistry (Easton) (05.10.2021)
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