Single domain antibodies: promising experimental and therapeutic tools in infection and immunity
Wesolowski, Janusz, Alzogaray, Vanina, Reyelt, Jan, Unger, Mandy, Juarez, Karla, Urrutia, Mariela, Cauerhff, Ana, Danquah, Welbeck, Rissiek, Björn, Scheuplein, Felix, Schwarz, Nicole, Adriouch, Sahil, Boyer, Olivier, Seman, Michel, Licea, Alexei, Serreze, David V., Goldbaum, Fernando A., Haag, Friedrich, Koch-Nolte, Friedrich
Published in Medical microbiology and immunology (01.08.2009)
Published in Medical microbiology and immunology (01.08.2009)
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Journal Article
Cancer Immunotherapeutic Potential of NKTT320, a Novel, Invariant, Natural Killer T Cell-Activating, Humanized Monoclonal Antibody
Patel, Nishant P, Guan, Peng, Bahal, Devika, Hashem, Tanwir, Scheuplein, Felix, Schaub, Robert, Nichols, Kim E, Das, Rupali
Published in International journal of molecular sciences (17.06.2020)
Published in International journal of molecular sciences (17.06.2020)
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Journal Article
Evaluation of STK17B as a cancer immunotherapy target utilizing highly potent and selective small molecule inhibitors
Scheuplein, Felix, Renner, Florian, Campbell, John E., Campbell, Robert, De Savi, Chris, Eckmann, Jan, Fischer, Holger, Ge, Jie, Green, Luke, Jakob, Peter, Kim, Joseph L., Kinkema, Caitlin, McGinn, Katie, Medina, Ricardo, Müller, Annemarie, Perez, Nisha, Perola, Emanuele, Timsit, Yoav, Traore, Tary, Hopfer, Ulrike, Tyanova, Stefka, Tzouros, Manuel, Wang, Ruduan, Woessner, Richard, Dorsch, Marion, Bischoff, James R.
Published in Frontiers in immunology (21.10.2024)
Published in Frontiers in immunology (21.10.2024)
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Journal Article
Mouse Invariant Monoclonal Antibody NKT14: A Novel Tool to Manipulate iNKT Cell Function In Vivo
Scheuplein, Felix, Lamont, Deanna J, Poynter, Matthew E, Boyson, Jonathan E, Serreze, David, Lundblad, Lennart K A, Mashal, Robert, Schaub, Robert
Published in PloS one (16.10.2015)
Published in PloS one (16.10.2015)
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Journal Article
The role of iNKT cells on the phenotypes of allergic airways in a mouse model
Lundblad, Lennart K.A, Gülec, Nazey, Poynter, Matthew E, DeVault, Victoria L, Dienz, Oliver, Boyson, Jonathan E, Daphtary, Nirav, Aliyeva, Minara, Ather, Jennifer L, Scheuplein, Felix, Schaub, Robert
Published in Pulmonary pharmacology & therapeutics (01.08.2017)
Published in Pulmonary pharmacology & therapeutics (01.08.2017)
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Journal Article
Invariant Natural Killer T-Cell Control of Type 1 Diabetes: A Dendritic Cell Genetic Decision of a Silver Bullet or Russian Roulette
DRIVER, John P, SCHEUPLEIN, Felix, CHEN, Yi-Guang, GRIER, Alexandra E, WILSON, S. Brian, SERREZE, David V
Published in Diabetes (New York, N.Y.) (01.02.2010)
Published in Diabetes (New York, N.Y.) (01.02.2010)
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Journal Article
Targeted Disruption of CD38 Accelerates Autoimmune Diabetes in NOD/Lt Mice by Enhancing Autoimmunity in an ADP-Ribosyltransferase 2-Dependent Fashion
Chen, Jing, Chen, Yi-Guang, Reifsnyder, Peter C, Schott, William H, Lee, Chul-Ho, Osborne, Melissa, Scheuplein, Felix, Haag, Friedrich, Koch-Nolte, Friedrich, Serreze, David V, Leiter, Edward H
Published in Journal of Immunology (15.04.2006)
Published in Journal of Immunology (15.04.2006)
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Journal Article
Pharmacokinetics and Pharmacodynamics after Subcutaneous Dosing of the iNKT Cell Depleting Antibody NKTT120
Schaub, Robert, Thariath, Abraham, Scheuplein, Felix, Mashal, Robert
Published in Blood (03.12.2015)
Published in Blood (03.12.2015)
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Journal Article
Abstract 1717: MAP4K1 inhibition enhances immune cell activation and anti-tumor immunity in preclinical tumor models
Faia, Kerrie, Toso, Alberto, Fetalvero, Kristina, Roche, Marly, Bench, Steven, O'Hearn, Erin, Cao, Qiongfang, Bright, Kerry-Ann, Paduraru, Debora, Romagnani, Andrea, Weng, Weifan, Zimmermann, Tina, Burke, Michael, Close, Joshua, Green, Luke, Kim, Joseph, Miduturu, Chandra, Ribeiro, Alison, Bacac, Marina, Herter, Sylvia, Perola, Emanuele, Sheets, Michael, Eckmann, Jan, Heidkamp, Gordon, Traore, Tary, Gerson, Erik, Woessner, Rich, Wolter, Carsten, Scheuplein, Felix, Perez, Nisha, LaBranche, Timothy, Silva, Grace, Ye, Chaoyang, Utt, Caitlin, Gross, Stefan, Bischoff, James R., Dorsch, Marion, Guzi, Tim, Hoeflich, Klaus, Brubaker, Jason
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Journal Article
Mouse Invariant TCR Specific Monoclonal Antibody NKT14: A Novel Tool To Manipulate Invariant NKT Cell Function In Vivo
Scheuplein, Felix, Thariath, Abraham, Mashal, Robert, Schaub, Robert
Published in Blood (15.11.2013)
Published in Blood (15.11.2013)
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Journal Article
Abstract 4294: Cancer immunotherapeutic potential of NKTT320, a novel human invariant natural killer T-cell activating monoclonal antibody
Das, Rupali, Scheuplein, Felix, Guan, Peng, Schaub, Robert, Nichols, Kim E.
Published in Cancer research (Chicago, Ill.) (01.08.2015)
Published in Cancer research (Chicago, Ill.) (01.08.2015)
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Journal Article
NAD-Induced T Cell Death: ADP-Ribosylation of Cell Surface Proteins by ART2 Activates the Cytolytic P2X7 Purinoceptor
Seman, Michel, Adriouch, Sahil, Scheuplein, Felix, Krebs, Christian, Freese, Dunja, Glowacki, Gustavo, Deterre, Phillipe, Haag, Friedrich, Koch-Nolte, Friedrich
Published in Immunity (Cambridge, Mass.) (01.10.2003)
Published in Immunity (Cambridge, Mass.) (01.10.2003)
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Journal Article
Adult Patients with Stable Sickle Cell Disease Prior to Treatment with the iNKT Cell Depleting Antibody NKTT120 Have Consistent and Elevated Numbers of Activated (CD69+) iNKT Cells Relative to Healthy Adult Volunteers
Mazanet, Rosemary, Schaub, Robert, Scheuplein, Felix, Eaton, Cheryl A., Mashal, Robert, Field, Joshua J.
Published in Blood (06.12.2014)
Published in Blood (06.12.2014)
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Journal Article
Abstract 653: NKTT320, a novel monoclonal antibody activates the immuno-stimulatory functions of human invariant natural killer T cells
Das, Rupali, Scheuplein, Felix, Patel, Nishant P., Guan, Peng, Schaub, Robert G., Nichols, Kim E.
Published in Cancer research (Chicago, Ill.) (01.10.2014)
Published in Cancer research (Chicago, Ill.) (01.10.2014)
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Journal Article
Abstract B30: Discovery and functional characterization of novel anti-PD-1 antibodies using ex vivo cell-based assays, single-cell immunoprofiling, and in vivo studies in humanized mice
Scheuplein, Felix, Ranganath, Sheila, McQuade, Thomas, Wang, Lei, Spaulding, Vikki, Vadde, Sri, Watkins-Yoon, Jennifer, Feng, Bin, Mehta, Shanu, Chiu, Maria Isabel, Nguyen, Cokey
Published in Cancer research (Chicago, Ill.) (01.08.2016)
Published in Cancer research (Chicago, Ill.) (01.08.2016)
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Journal Article
Abstract 4871: Two novel anti-PD-1 antibodies, 244C8 and 388D4, elicit in vivo antitumor efficacy in a lung PDX tumorgraft in immuno-humanized NSG mice
Scheuplein, Felix, Ranganath, Sheila, Feng, Bin, McQuade, Thomas, Wang, Lei, Spaulding, Vikki, Vadde, Sri, Mehta, Shanu, Chiu, Maria Isabel, Nguyen, Cokey
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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Journal Article
Extracellular NAD and ATP: Partners in immune cell modulation
Haag, Friedrich, Adriouch, Sahil, Braß, Anette, Jung, Caroline, Möller, Sina, Scheuplein, Felix, Bannas, Peter, Seman, Michel, Koch-Nolte, Friedrich
Published in Purinergic signalling (01.03.2007)
Published in Purinergic signalling (01.03.2007)
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Journal Article