Search Results - "SCHEUNER, Donalyn" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

The IRE1α/XBP1s Pathway Is Essential for the Glucose Response and Protection of β Cells

The IRE1α/XBP1s Pathway Is Essential for the Glucose Response and Protection of β Cells

by Hassler, Justin R, Scheuner, Donalyn L, Wang, Shiyu, Han, Jaeseok, Kodali, Vamsi K, Li, Philip, Nguyen, Julie, George, Jenny S, Davis, Cory, Wu, Shengyang P, Bai, Yongsheng, Sartor, Maureen, Cavalcoli, James, Malhi, Harmeet, Baudouin, Gregory, Zhang, Yaoyang, Yates, III, John R, Itkin-Ansari, Pamela, Volkmann, Niels, Kaufman, Randal J
Published in PLoS biology (01.10.2015)

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PDIA1/P4HB is required for efficient proinsulin maturation and ß cell health in response to diet induced obesity

PDIA1/P4HB is required for efficient proinsulin maturation and ß cell health in response to diet induced obesity

by Jang, Insook, Pottekat, Anita, Poothong, Juthakorn, Yong, Jing, Lagunas-Acosta, Jacqueline, Charbono, Adriana, Chen, Zhouji, Scheuner, Donalyn L, Liu, Ming, Itkin-Ansari, Pamela, Arvan, Peter, Kaufman, Randal J
Published in eLife (11.06.2019)

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Ppp1r15 gene knockout reveals an essential role for translation initiation factor 2 alpha (eIF2α) dephosphorylation in mammalian development

Ppp1r15 gene knockout reveals an essential role for translation initiation factor 2 alpha (eIF2α) dephosphorylation in mammalian development

by Harding, Heather P, Zhang, Yuhong, Scheuner, Donalyn, Chen, Jane-Jane, Kaufman, Randal J, Ron, David
Published in Proceedings of the National Academy of Sciences - PNAS (10.02.2009)

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Stress granules and processing bodies are dynamically linked sites of mRNP remodeling

Stress granules and processing bodies are dynamically linked sites of mRNP remodeling

by Kedersha, Nancy, Stoecklin, Georg, Ayodele, Maranatha, Yacono, Patrick, Lykke-Andersen, Jens, Fitzler, Marvin J, Scheuner, Donalyn, Kaufman, Randal J, Golan, David E, Anderson, Paul
Published in The Journal of cell biology (20.06.2005)

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ER stress-regulated translation increases tolerance to extreme hypoxia and promotes tumor growth

ER stress-regulated translation increases tolerance to extreme hypoxia and promotes tumor growth

by Bi, Meixia, Naczki, Christine, Koritzinsky, Marianne, Fels, Diane, Blais, Jaime, Hu, Nianping, Harding, Heather, Novoa, Isabelle, Varia, Mahesh, Raleigh, James, Scheuner, Donalyn, Kaufman, Randal J, Bell, John, Ron, David, Wouters, Bradly G, Koumenis, Constantinos
Published in The EMBO journal (05.10.2005)

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Phosphorylation of Eukaryotic Translation Initiation Factor 2α Coordinates rRNA Transcription and Translation Inhibition during Endoplasmic Reticulum Stress

Phosphorylation of Eukaryotic Translation Initiation Factor 2α Coordinates rRNA Transcription and Translation Inhibition during Endoplasmic Reticulum Stress

by DuRose, Jenny B., Scheuner, Donalyn, Kaufman, Randal J., Rothblum, Lawrence I., Niwa, Maho
Published in Molecular and Cellular Biology (01.08.2009)

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Protein kinase R contributes to immunity against specific viruses by regulating interferon mRNA integrity

Protein kinase R contributes to immunity against specific viruses by regulating interferon mRNA integrity

by Schulz, Oliver, Pichlmair, Andreas, Rehwinkel, Jan, Rogers, Neil C, Scheuner, Donalyn, Kato, Hiroki, Takeuchi, Osamu, Akira, Shizuo, Kaufman, Randal J, Reis e Sousa, Caetano
Published in Cell host & microbe (20.05.2010)

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Translational Repression Mediates Activation of Nuclear Factor Kappa B by Phosphorylated Translation Initiation Factor 2

Translational Repression Mediates Activation of Nuclear Factor Kappa B by Phosphorylated Translation Initiation Factor 2

by Deng, Jing, Lu, Phoebe D., Zhang, Yuhong, Scheuner, Donalyn, Kaufman, Randal J., Sonenberg, Nahum, Harding, Heather P., Ron, David
Published in Molecular and Cellular Biology (01.12.2004)

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Heme-regulated Inhibitor Kinase-mediated Phosphorylation of Eukaryotic Translation Initiation Factor 2 Inhibits Translation, Induces Stress Granule Formation, and Mediates Survival upon Arsenite Exposure

Heme-regulated Inhibitor Kinase-mediated Phosphorylation of Eukaryotic Translation Initiation Factor 2 Inhibits Translation, Induces Stress Granule Formation, and Mediates Survival upon Arsenite Exposure

by McEwen, Edward, Kedersha, Nancy, Song, Benbo, Scheuner, Donalyn, Gilks, Natalie, Han, Anping, Chen, Jane-Jane, Anderson, Paul, Kaufman, Randal J.
Published in The Journal of biological chemistry (29.04.2005)

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Control of mRNA translation preserves endoplasmic reticulum function in beta cells and maintains glucose homeostasis

Control of mRNA translation preserves endoplasmic reticulum function in beta cells and maintains glucose homeostasis

by Schuit, Frans C, Kaufman, Randal J, Scheuner, Donalyn, Mierde, Dirk Vander, Song, Benbo, Flamez, Daisy, Creemers, John W M, Tsukamoto, Katsura, Ribick, Mark
Published in Nature medicine (01.07.2005)

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Phosphorylation of the α Subunit of Eukaryotic Initiation Factor 2 Is Required for Activation of NF-κB in Response to Diverse Cellular Stresses

Phosphorylation of the α Subunit of Eukaryotic Initiation Factor 2 Is Required for Activation of NF-κB in Response to Diverse Cellular Stresses

by Jiang, Hao-Yuan, Wek, Sheree A., McGrath, Barbara C., Scheuner, Donalyn, Kaufman, Randal J., Cavener, Douglas R., Wek, Ronald C.
Published in Molecular and Cellular Biology (01.08.2003)

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Translational Control Is Required for the Unfolded Protein Response and In Vivo Glucose Homeostasis

Translational Control Is Required for the Unfolded Protein Response and In Vivo Glucose Homeostasis

by Scheuner, Donalyn, Song, Benbo, McEwen, Edward, Liu, Chuan, Laybutt, Ross, Gillespie, Patrick, Saunders, Thom, Bonner-Weir, Susan, Kaufman, Randal J
Published in Molecular cell (01.06.2001)

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The unfolded protein response in nutrient sensing and differentiation

The unfolded protein response in nutrient sensing and differentiation

by Kaufman, Randal J, Scheuner, Donalyn, Schröder, Martin, Shen, Xiaohua, Lee, Kyungho, Liu, Chuan Yin, Arnold, Stacey M
Published in Nature reviews. Molecular cell biology (01.06.2002)

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Regulation of starvation- and virus-induced autophagy by the eIF2α kinase signaling pathway

Regulation of starvation- and virus-induced autophagy by the eIF2α kinase signaling pathway

by Talloczy, Z, Jiang, W, Virgin IV, HW, Leib, DA, Scheuner, D, Kaufman, R J, Eskelinen, E, Levine, B
Published in Proceedings of the National Academy of Sciences - PNAS (08.01.2002)

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Cytoprotection by pre-emptive conditional phosphorylation of translation initiation factor 2

Cytoprotection by pre-emptive conditional phosphorylation of translation initiation factor 2

by Lu, Phoebe D, Jousse, Céline, Marciniak, Stefan J, Zhang, Yuhong, Novoa, Isabel, Scheuner, Donalyn, Kaufman, Randal J, Ron, David, Harding, Heather P
Published in The EMBO journal (14.01.2004)

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Activation of GCN2 in UV-Irradiated Cells Inhibits Translation

Activation of GCN2 in UV-Irradiated Cells Inhibits Translation

by Deng, Jing, Harding, Heather P., Raught, Brian, Gingras, Anne-Claude, Berlanga, Juan Jose, Scheuner, Donalyn, Kaufman, Randal J., Ron, David, Sonenberg, Nahum
Published in Current biology (06.08.2002)

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Bioactive small molecules reveal antagonism between the integrated stress response and sterol-regulated gene expression

Bioactive small molecules reveal antagonism between the integrated stress response and sterol-regulated gene expression

by Harding, Heather P., Zhang, Yuhong, Khersonsky, Sonya, Marciniak, Stefan, Scheuner, Donalyn, Kaufman, Randal J., Javitt, Norman, Chang, Young-Tae, Ron, David
Published in Cell metabolism (01.12.2005)

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Novel Function of PERK as a Mediator of Force-induced Apoptosis

Novel Function of PERK as a Mediator of Force-induced Apoptosis

by Mak, Baldwin C., Wang, Qin, Laschinger, Carol, Lee, Wilson, Ron, David, Harding, Heather P., Kaufman, Randal J., Scheuner, Donalyn, Austin, Richard C., McCulloch, Christopher A.
Published in The Journal of biological chemistry (22.08.2008)

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The Unfolded Protein Response: A Pathway That Links Insulin Demand with β-Cell Failure and Diabetes

The Unfolded Protein Response: A Pathway That Links Insulin Demand with β-Cell Failure and Diabetes

by Scheuner, Donalyn, Kaufman, Randal J
Published in Endocrine reviews (01.05.2008)

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Chop deletion reduces oxidative stress, improves beta cell function, and promotes cell survival in multiple mouse models of diabetes

Chop deletion reduces oxidative stress, improves beta cell function, and promotes cell survival in multiple mouse models of diabetes

by Song, Benbo, Scheuner, Donalyn, Ron, David, Pennathur, Subramaniam, Kaufman, Randal J
Published in The Journal of clinical investigation (01.10.2008)

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