High-Throughput Assay and Discovery of Small Molecules that Interrupt Malaria Transmission
Plouffe, David M., Wree, Melanie, Du, Alan Y., Meister, Stephan, Li, Fengwu, Patra, Kailash, Lubar, Aristea, Okitsu, Shinji L., Flannery, Erika L., Kato, Nobutaka, Tanaseichuk, Olga, Comer, Eamon, Zhou, Bin, Kuhen, Kelli, Zhou, Yingyao, Leroy, Didier, Schreiber, Stuart L., Scherer, Christina A., Vinetz, Joseph, Winzeler, Elizabeth A.
Published in Cell host & microbe (13.01.2016)
Published in Cell host & microbe (13.01.2016)
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Journal Article
Complex lipid metabolic remodeling is required for efficient hepatitis C virus replication
Hofmann, Sarah, Krajewski, Matthias, Scherer, Christina, Scholz, Verena, Mordhorst, Valerie, Truschow, Pavel, Schöbel, Anja, Reimer, Rudolph, Schwudke, Dominik, Herker, Eva
Published in Biochimica et biophysica acta. Molecular and cell biology of lipids (01.09.2018)
Published in Biochimica et biophysica acta. Molecular and cell biology of lipids (01.09.2018)
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Development and Validation of a Novel Leishmania donovani Screening Cascade for High-Throughput Screening Using a Novel Axenic Assay with High Predictivity of Leishmanicidal Intracellular Activity
Nühs, Andrea, De Rycker, Manu, Manthri, Sujatha, Comer, Eamon, Scherer, Christina A, Schreiber, Stuart L, Ioset, Jean-Robert, Gray, David W
Published in PLoS neglected tropical diseases (01.09.2015)
Published in PLoS neglected tropical diseases (01.09.2015)
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Journal Article
Discovery of Antimalarial Azetidine-2-carbonitriles That Inhibit P. falciparum Dihydroorotate Dehydrogenase
Maetani, Micah, Kato, Nobutaka, Jabor, Valquiria A. P, Calil, Felipe A, Nonato, Maria Cristina, Scherer, Christina A, Schreiber, Stuart L
Published in ACS medicinal chemistry letters (13.04.2017)
Published in ACS medicinal chemistry letters (13.04.2017)
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Journal Article
Extracellular 2′-5′ Oligoadenylate Synthetase Stimulates RNase L-Independent Antiviral Activity: a Novel Mechanism of Virus-Induced Innate Immunity
KRISTIANSEN, Helle, SCHERER, Christina A, PALUDAN, Søren R, HARTMANN, Rune, MCVEAN, Maralee, IADONATO, Shawn P, VENDS, Susanne, THAVACHELVAM, Karthiga, STEFFENSEN, Thomas B, HORAN, Kristy A, KURI, Thomas, WEBER, Friedemann
Published in Journal of Virology (01.11.2010)
Published in Journal of Virology (01.11.2010)
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Journal Article
STK33 kinase inhibitor BRD-8899 has no effect on KRAS-dependent cancer cell viability
Luo, Tuoping, Masson, Kristina, Jaffe, Jacob D, Silkworth, Whitney, Ross, Nathan T, Scherer, Christina A, Scholl, Claudia, Fröhling, Stefan, Carr, Steven A, Stern, Andrew M, Schreiber, Stuart L, Golub, Todd R
Published in Proceedings of the National Academy of Sciences - PNAS (21.02.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (21.02.2012)
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Journal Article
Association of the FTO Gene With BMI
Hunt, Steven C., Stone, Steven, Xin, Yuanpei, Scherer, Christina A., Magness, Charles L., Iadonato, Shawn P., Hopkins, Paul N., Adams, Ted D.
Published in Obesity (Silver Spring, Md.) (01.04.2008)
Published in Obesity (Silver Spring, Md.) (01.04.2008)
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Journal Article
A Potent and Selective Quinoxalinone-Based STK33 Inhibitor Does Not Show Synthetic Lethality in KRAS-Dependent Cells
Weïwer, Michel, Spoonamore, James, Wei, Jingqiang, Guichard, Boris, Ross, Nathan T, Masson, Kristina, Silkworth, Whitney, Dandapani, Sivaraman, Palmer, Michelle, Scherer, Christina A, Stern, Andrew M, Schreiber, Stuart L, Munoz, Benito
Published in ACS medicinal chemistry letters (13.12.2012)
Published in ACS medicinal chemistry letters (13.12.2012)
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Journal Article
An Aedes aegypti-Derived Ago2 Knockout Cell Line to Investigate Arbovirus Infections
Scherer, Christina, Knowles, Jack, Sreenu, Vattipally B., Fredericks, Anthony C., Fuss, Janina, Maringer, Kevin, Fernandez-Sesma, Ana, Merits, Andres, Varjak, Margus, Kohl, Alain, Schnettler, Esther
Published in Viruses (03.06.2021)
Published in Viruses (03.06.2021)
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Journal Article
Diversity-Oriented Synthesis Probe Targets Plasmodium falciparum Cytochrome b Ubiquinone Reduction Site and Synergizes With Oxidation Site Inhibitors
Lukens, Amanda K., Heidebrecht, Richard W., Mulrooney, Carol, Beaudoin, Jennifer A., Comer, Eamon, Duvall, Jeremy R., Fitzgerald, Mark E., Masi, Daniela, Galinsky, Kevin, Scherer, Christina A., Palmer, Michelle, Munoz, Benito, Foley, Michael, Schreiber, Stuart L., Wiegand, Roger C., Wirth, Dyann F.
Published in The Journal of infectious diseases (01.04.2015)
Published in The Journal of infectious diseases (01.04.2015)
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Journal Article
High-Throughput Luciferase-Based Assay for the Discovery of Therapeutics That Prevent Malaria
Swann, Justine, Corey, Victoria, Scherer, Christina A, Kato, Nobutaka, Comer, Eamon, Maetani, Micah, Antonova-Koch, Yevgeniya, Reimer, Christin, Gagaring, Kerstin, Ibanez, Maureen, Plouffe, David, Zeeman, Anne-Marie, Kocken, Clemens H. M, McNamara, Case W, Schreiber, Stuart L, Campo, Brice, Winzeler, Elizabeth A, Meister, Stephan
Published in ACS infectious diseases (08.04.2016)
Published in ACS infectious diseases (08.04.2016)
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Journal Article
Diversity-Oriented Synthesis-Facilitated Medicinal Chemistry: Toward the Development of Novel Antimalarial Agents
Comer, Eamon, Beaudoin, Jennifer A, Kato, Nobutaka, Fitzgerald, Mark E, Heidebrecht, Richard W, Lee, Maurice duPont, Masi, Daniela, Mercier, Marion, Mulrooney, Carol, Muncipinto, Giovanni, Rowley, Ann, Crespo-Llado, Keila, Serrano, Adelfa E, Lukens, Amanda K, Wiegand, Roger C, Wirth, Dyann F, Palmer, Michelle A, Foley, Michael A, Munoz, Benito, Scherer, Christina A, Duvall, Jeremy R, Schreiber, Stuart L
Published in Journal of medicinal chemistry (23.10.2014)
Published in Journal of medicinal chemistry (23.10.2014)
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Journal Article
Novel diversity-oriented synthesis-derived respiratory syncytial virus inhibitors identified via a high throughput replicon-based screen
Duvall, Jeremy R, VerPlank, Lynn, Ludeke, Barbara, McLeod, Sarah M, Lee, 4th, Maurice D, Vishwanathan, Karthick, Mulrooney, Carol A, Le Quement, Sebastian, Yu, Qin, Palmer, Michelle A, Fleming, Paul, Fearns, Rachel, Foley, Michael A, Scherer, Christina A
Published in Antiviral research (01.07.2016)
Published in Antiviral research (01.07.2016)
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Journal Article
Antiviral RNAi Response against the Insect-Specific Agua Salud Alphavirus
Altinli, Mine, Leggewie, Mayke, Badusche, Marlis, Gyanwali, Rashwita, Scherer, Christina, Schulze, Jonny, Sreenu, Vattipally B, Fegebank, Marvin, Zibrat, Bernhard, Fuss, Janina, Junglen, Sandra, Schnettler, Esther
Published in mSphere (23.02.2022)
Published in mSphere (23.02.2022)
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Journal Article
Identification of Regulators of Polyploidization Presents Therapeutic Targets for Treatment of AMKL
Wen, Qiang, Goldenson, Benjamin, Silver, Serena J., Schenone, Monica, Dancik, Vlado, Huang, Zan, Wang, Ling-Zhi, Lewis, Timothy A., An, W. Frank, Li, Xiaoyu, Bray, Mark-Anthony, Thiollier, Clarisse, Diebold, Lauren, Gilles, Laure, Vokes, Martha S., Moore, Christopher B., Bliss-Moreau, Meghan, VerPlank, Lynn, Tolliday, Nicola J., Mishra, Rama, Vemula, Sasidhar, Shi, Jianjian, Wei, Lei, Kapur, Reuben, Lopez, Cécile K., Gerby, Bastien, Ballerini, Paola, Pflumio, Francoise, Gilliland, D. Gary, Goldberg, Liat, Birger, Yehudit, Izraeli, Shai, Gamis, Alan S., Smith, Franklin O., Woods, William G., Taub, Jeffrey, Scherer, Christina A., Bradner, James E., Goh, Boon-Cher, Mercher, Thomas, Carpenter, Anne E., Gould, Robert J., Clemons, Paul A., Carr, Steven A., Root, David E., Schreiber, Stuart L., Stern, Andrew M., Crispino, John D.
Published in Cell (03.08.2012)
Published in Cell (03.08.2012)
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Journal Article
Macrocyclic Hedgehog Pathway Inhibitors: Optimization of Cellular Activity and Mode of Action Studies
Dockendorff, Chris, Nagiec, Marek M, Weïwer, Michel, Buhrlage, Sara, Ting, Amal, Nag, Partha P, Germain, Andrew, Kim, Han-Je, Youngsaye, Willmen, Scherer, Christina, Bennion, Melissa, Xue, Linlong, Stanton, Benjamin Z, Lewis, Timothy A, MacPherson, Lawrence, Palmer, Michelle, Foley, Michael A, Perez, José R, Schreiber, Stuart L
Published in ACS medicinal chemistry letters (11.10.2012)
Published in ACS medicinal chemistry letters (11.10.2012)
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Journal Article
Identification of Highly Specific Diversity-Oriented Synthesis-Derived Inhibitors of Clostridium difficile
Duvall, Jeremy R, Bedard, Leanne, Naylor-Olsen, Adel M, Manson, Abigail L, Bittker, Joshua A, Sun, Wenye, Fitzgerald, Mark E, He, Zhenmin, Lee, Maurice D, Marie, Jean-Charles, Muncipinto, Giovanni, Rush, Diane, Xu, Deming, Xu, Huisheng, Zhang, Mingliang, Earl, Ashlee M, Palmer, Michelle A, Foley, Michael A, Vacca, Joseph P, Scherer, Christina A
Published in ACS infectious diseases (12.05.2017)
Published in ACS infectious diseases (12.05.2017)
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Journal Article
Distinct gene expression profiles in peripheral blood mononuclear cells from patients infected with vaccinia virus, yellow fever 17D virus, or upper respiratory infections
Scherer, Christina A, Magness, Charles L, Steiger, Kathryn V, Poitinger, Nicholas D, Caputo, Christine M, Miner, Douglas G, Winokur, Patricia L, Klinzman, Donna, McKee, Janice, Pilar, Christine, Ward, Patricia A, Gillham, Martha H, Haulman, N. Jean, Stapleton, Jack T, Iadonato, Shawn P
Published in Vaccine (29.08.2007)
Published in Vaccine (29.08.2007)
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Journal Article
Arginine N-Methyltransferase 1 Is Required for Early Postimplantation Mouse Development, but Cells Deficient in the Enzyme Are Viable
Pawlak, Maciej R., Scherer, Christina A., Chen, Jin, Roshon, Michael J., Ruley, H. Earl
Published in Molecular and Cellular Biology (01.07.2000)
Published in Molecular and Cellular Biology (01.07.2000)
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