Control of Metazoan Heme Homeostasis by a Conserved Multidrug Resistance Protein
Korolnek, Tamara, Zhang, Jianbing, Beardsley, Simon, Scheffer, George L., Hamza, Iqbal
Published in Cell metabolism (03.06.2014)
Published in Cell metabolism (03.06.2014)
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Variations in ATP-Binding Cassette Transporter Regulation during the Progression of Human Nonalcoholic Fatty Liver Disease
HARDWICK, Rhiannon N, FISHER, Craig D, CANET, Mark J, SCHEFFER, George L, CHERRINGTON, Nathan J
Published in Drug metabolism and disposition (01.12.2011)
Published in Drug metabolism and disposition (01.12.2011)
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Oxidative and electrophilic stress induces multidrug resistance–associated protein transporters via the nuclear factor‐E2–related factor‐2 transcriptional pathway
Maher, Jonathan M., Dieter, Matthew Z., Aleksunes, Lauren M., Slitt, Angela L., Guo, Grace, Tanaka, Yuji, Scheffer, George L., Chan, Jefferson Y., Manautou, Jose E., Chen, Ying, Dalton, Timothy P., Yamamoto, Masayuki, Klaassen, Curtis D.
Published in Hepatology (Baltimore, Md.) (01.11.2007)
Published in Hepatology (Baltimore, Md.) (01.11.2007)
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Expression levels of the ABCG2 multidrug transporter in human erythrocytes correspond to pharmacologically relevant genetic variations
Kasza, Ildikó, Várady, György, Andrikovics, Hajnalka, Koszarska, Magdalena, Tordai, Attila, Scheffer, George L, Németh, Adrienn, Szakács, Gergely, Sarkadi, Balázs
Published in PloS one (15.11.2012)
Published in PloS one (15.11.2012)
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Mrp4 Confers Resistance to Topotecan and Protects the Brain from Chemotherapy
Leggas, Markos, Adachi, Masashi, Scheffer, George L., Sun, Daxi, Wielinga, Peter, Du, Guoqing, Mercer, Kelly E., Zhuang, Yanli, Panetta, John C., Johnston, Brad, Scheper, Rik J., Stewart, Clinton F., Schuetz, John D.
Published in Molecular and Cellular Biology (01.09.2004)
Published in Molecular and Cellular Biology (01.09.2004)
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The Breast Cancer Resistance Protein Protects against a Major Chlorophyll-Derived Dietary Phototoxin and Protoporphyria
Jonker, Johan W., Buitelaar, Marije, Wagenaar, Els, van der Valk, Martin A., Scheffer, George L., Scheper, Rik J., Plösch, Torsten, Kuipers, Folkert, Ronald P.J. Oude Elferink, Rosing, Hilde, Beijnen, Jos H., Schinkel, Alfred H.
Published in Proceedings of the National Academy of Sciences - PNAS (26.11.2002)
Published in Proceedings of the National Academy of Sciences - PNAS (26.11.2002)
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Localization of Breast Cancer Resistance Protein (BCRP) in Microvessel Endothelium of Human Control and Epileptic Brain
Aronica, Eleonora, Gorter, Jan A., Redeker, Sandra, Van Vliet, Erwin A., Ramkema, Marja, Scheffer, George L., Scheper, Rik J., Van Der Valk, Paul, Leenstra, Sieger, Baayen, Johannes C., Spliet, Wim G. M., Troost, Dirk
Published in Epilepsia (Copenhagen) (01.06.2005)
Published in Epilepsia (Copenhagen) (01.06.2005)
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The EGFR pathway regulates BCRP expression in NSCLC cells: role of erlotinib
Porcelli, Letizia, Giovannetti, Elisa, Assaraf, Yehuda G, Jansen, Gerrit, Scheffer, George L, Kathman, Ietje, Azzariti, Amalia, Paradiso, Angelo, Peters, Godefridus J
Published in Current drug targets (01.01.2014)
Published in Current drug targets (01.01.2014)
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Multifactorial resistance to aminopeptidase inhibitor prodrug CHR2863 in myeloid leukemia cells: down-regulation of carboxylesterase 1, drug sequestration in lipid droplets and pro-survival activation ERK/Akt/mTOR
Verbrugge, Sue Ellen, Al, Marjon, Assaraf, Yehuda G, Kammerer, Sarah, Chandrupatla, Durga M S H, Honeywell, Richard, Musters, Rene P J, Giovannetti, Elisa, O'Toole, Tom, Scheffer, George L, Krige, David, de Gruijl, Tanja D, Niessen, Hans W M, Lems, Willem F, Kramer, Pieternella A, Scheper, Rik J, Cloos, Jacqueline, Ossenkoppele, Gert J, Peters, Godefridus J, Jansen, Gerrit
Published in Oncotarget (02.02.2016)
Published in Oncotarget (02.02.2016)
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The wide spectrum of multidrug resistance 3 deficiency: from neonatal cholestasis to cirrhosis of adulthood
Jacquemin, E, De Vree, J M, Cresteil, D, Sokal, E M, Sturm, E, Dumont, M, Scheffer, G L, Paul, M, Burdelski, M, Bosma, P J, Bernard, O, Hadchouel, M, Elferink, R P
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2001)
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2001)
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Expression and Cellular Distribution of Multidrug Resistance–related Proteins in the Hippocampus of Patients with Mesial Temporal Lobe Epilepsy
Aronica, Eleonora, Gorter, Jan A., Ramkema, Marja, Redeker, Sandra, Özbas‐Gerçeker, Filiz, Van Vliet, Edwin A., Scheffer, George L., Scheper, Rik J., Van Der Valk, Paul, Baayen, Johannes C., Troost, Dirk
Published in Epilepsia (Copenhagen) (01.05.2004)
Published in Epilepsia (Copenhagen) (01.05.2004)
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Disruption of Abcc6 in the mouse: novel insight in the pathogenesis of pseudoxanthoma elasticum
Gorgels, Theo G.M.F., Hu, Xiaofeng, Scheffer, George L., van der Wal, Allard C., Toonstra, Johan, de Jong, Paulus T.V.M., van Kuppevelt, Toin H., Levelt, Christiaan N., de Wolf, Anneke, Loves, Willem J.P., Scheper, Rik J., Peek, Ron, Bergen, Arthur A.B.
Published in Human molecular genetics (01.07.2005)
Published in Human molecular genetics (01.07.2005)
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MRP3, an Organic Anion Transporter Able to Transport Anti-Cancer Drugs
Kool, Marcel, van der Linden, Marcel, de Haas, Marcel, Scheffer, George L., J. Marleen L. De Vree, Smith, Alexander J., Jansen, Gerrit, Peters, Godefridus J., Ponne, Nico, Scheper, Rik J., Ronald P. J. Oude Elferink, Baas, Frank, Borst, Piet
Published in Proceedings of the National Academy of Sciences - PNAS (08.06.1999)
Published in Proceedings of the National Academy of Sciences - PNAS (08.06.1999)
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The Effect of Low pH on Breast Cancer Resistance Protein (ABCG2)-Mediated Transport of Methotrexate, 7-Hydroxymethotrexate, Methotrexate Diglutamate, Folic Acid, Mitoxantrone, Topotecan, and Resveratrol in In Vitro Drug Transport Models
Breedveld, Pauline, Pluim, Dick, Cipriani, Greta, Dahlhaus, Femke, van Eijndhoven, Maria A J, de Wolf, Cornelia J F, Kuil, Annemieke, Beijnen, Jos H, Scheffer, George L, Jansen, Gerrit, Borst, Piet, Schellens, Jan H M
Published in Molecular pharmacology (01.01.2007)
Published in Molecular pharmacology (01.01.2007)
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Altered arsenic disposition in experimental nonalcoholic fatty liver disease
Canet, Mark J, Hardwick, Rhiannon N, Lake, April D, Kopplin, Michael J, Scheffer, George L, Klimecki, Walter T, Gandolfi, A Jay, Cherrington, Nathan J
Published in Drug metabolism and disposition (01.09.2012)
Published in Drug metabolism and disposition (01.09.2012)
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ABCG2 overexpression in colon cancer cells resistant to SN38 and in irinotecan‐treated metastases
Candeil, Laurent, Gourdier, Isabelle, Peyron, Delphine, Vezzio, Nadia, Copois, Virginie, Bibeau, Frederic, Orsetti, Beatrice, Scheffer, George L., Ychou, Marc, Khan, Qasim A., Pommier, Yves, Pau, Bernard, Martineau, Pierre, Del Rio, Maguy
Published in International journal of cancer (10.05.2004)
Published in International journal of cancer (10.05.2004)
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Hepatic Mrp4 induction following acetaminophen exposure is dependent on Kupffer cell function
Campion, Sarah N, Johnson, Rachel, Aleksunes, Lauren M, Goedken, Michael J, van Rooijen, Nico, Scheffer, George L, Cherrington, Nathan J, Manautou, José E
Published in American journal of physiology: Gastrointestinal and liver physiology (01.08.2008)
Published in American journal of physiology: Gastrointestinal and liver physiology (01.08.2008)
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Journal Article
Mitochondria-mediated apoptosis operating irrespective of multidrug resistance in breast cancer cells by the anticancer agent prodigiosin
Soto-Cerrato, Vanessa, Llagostera, Esther, Montaner, Beatriz, Scheffer, George L., Perez-Tomas, Ricardo
Published in Biochemical pharmacology (01.10.2004)
Published in Biochemical pharmacology (01.10.2004)
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