Aptamer ARC19499 mediates a procoagulant hemostatic effect by inhibiting tissue factor pathway inhibitor
Waters, Emily K., Genga, Ryan M., Schwartz, Michael C., Nelson, Jennifer A., Schaub, Robert G., Olson, Karen A., Kurz, Jeffrey C., McGinness, Kathleen E.
Published in Blood (19.05.2011)
Published in Blood (19.05.2011)
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First-in-human evaluation of anti von Willebrand factor therapeutic aptamer ARC1779 in healthy volunteers
Gilbert, James C, DeFeo-Fraulini, Tia, Hutabarat, Renta M, Horvath, Christopher J, Merlino, Patricia G, Marsh, H Nicholas, Healy, Judith M, Boufakhreddine, Sleiman, Holohan, Thomas V, Schaub, Robert G
Published in Circulation (New York, N.Y.) (04.12.2007)
Published in Circulation (New York, N.Y.) (04.12.2007)
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Prophylactic P-selectin inhibition with PSI-421 promotes resolution of venous thrombosis without anticoagulation
Meier, Thomas R, Myers, Jr, Daniel D, Wrobleski, Shirley K, Zajkowski, Paul J, Hawley, Angela E, Bedard, Patricia W, Ballard, Nicole E, Londy, Frank J, Kaila, Neelu, Vlasuk, George P, Schaub, Robert G, Wakefield, Thomas W
Published in Thrombosis and haemostasis (01.02.2008)
Published in Thrombosis and haemostasis (01.02.2008)
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Rotigaptide (ZP123) Prevents Spontaneous Ventricular Arrhythmias and Reduces Infarct Size During Myocardial Ischemia/Reperfusion Injury in Open-Chest Dogs
Hennan, James K, Swillo, Robert E, Morgan, Gwen A, Keith, Jr, James C, Schaub, Robert G, Smith, Robert P, Feldman, Hal S, Haugan, Ketil, Kantrowitz, Joel, Wang, Phil J, Abu-Qare, Aqel, Butera, John, Larsen, Bjarne D, Crandall, David L
Published in The Journal of pharmacology and experimental therapeutics (01.04.2006)
Published in The Journal of pharmacology and experimental therapeutics (01.04.2006)
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The von Willebrand factor antagonist (GPG-290) prevents coronary thrombosis without prolongation of bleeding time
Wadanoli, Michael, Sako, Dianne, Shaw, Gray D, Schaub, Robert G, Wang, Qin, Tchernychev, Boris, Xu, Jin, Porter, Thomas J, Huang, Qinheng
Published in Thrombosis and haemostasis (01.08.2007)
Published in Thrombosis and haemostasis (01.08.2007)
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Characterization of the Novel P-Selectin Inhibitor PSI-697 [2-(4-Chlorobenzyl)-3-hydroxy-7,8,9,10-tetrahydrobenzo[h] Quinoline-4-carboxylic acid] in Vitro and in Rodent Models of Vascular Inflammation and Thrombosis
Bedard, Patricia W, Clerin, Valerie, Sushkova, Natalia, Tchernychev, Boris, Antrilli, Thomas, Resmini, Christine, Keith, Jr, James C, Hennan, James K, Kaila, Neelu, Debernardo, Silvano, Janz, Kristin, Wang, Qin, Crandall, David L, Schaub, Robert G, Shaw, Gray D, Carter, Laura L
Published in The Journal of pharmacology and experimental therapeutics (01.02.2008)
Published in The Journal of pharmacology and experimental therapeutics (01.02.2008)
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P-Selectin–Dependent Inhibition of Thrombosis During Venous Stasis
Eppihimer, Michael J, Schaub, Robert G
Published in Arteriosclerosis, thrombosis, and vascular biology (01.11.2000)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.11.2000)
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Pharmacologic inhibition of platelet vWF-GPIb alpha interaction prevents coronary artery thrombosis
Hennan, James K, Swillo, Robert E, Morgan, Gwen A, Leik, Courtney E, Brooks, Jonathan M, Shaw, Gray D, Schaub, Robert G, Crandall, David L, Vlasuk, George P
Published in Thrombosis and haemostasis (01.03.2006)
Published in Thrombosis and haemostasis (01.03.2006)
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P-selectin inhibition therapeutically promotes thrombus resolution and prevents vein wall fibrosis better than enoxaparin and an inhibitor to von Willebrand factor
Diaz, Jose A, Wrobleski, Shirley K, Alvarado, Christine M, Hawley, Angela E, Doornbos, Nichole K, Lester, Patrick A, Lowe, Suzan E, Gabriel, Joy E, Roelofs, Karen J, Henke, Peter K, Schaub, Robert G, Wakefield, Thomas W, Myers, Jr, Daniel D
Published in Arteriosclerosis, thrombosis, and vascular biology (01.04.2015)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.04.2015)
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Serum myeloperoxidase levels are associated with the future risk of coronary artery disease in apparently healthy individuals : The EPIC-Norfolk prospective population study
MEUWESE, Marijn C, STROES, Erik S. G, MATTHIJS BOEKHOLDT, S, HAZEN, Stanley L, VAN MIERT, Joram N, KUIVENHOVEN, Jan Albert, SCHAUB, Robert G, WAREHAM, Nicholas J, LUBEN, Robert, KASTELEIN, John J. P, KHAW, Kay-Tee
Published in Journal of the American College of Cardiology (10.07.2007)
Published in Journal of the American College of Cardiology (10.07.2007)
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Inhibition of cell adhesion by anti–P-selectin aptamer: a new potential therapeutic agent for sickle cell disease
Gutsaeva, Diana R., Parkerson, James B., Yerigenahally, Shobha D., Kurz, Jeffrey C., Schaub, Robert G., Ikuta, Tohru, Head, C. Alvin
Published in Blood (13.01.2011)
Published in Blood (13.01.2011)
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Recombinant soluble form of PSGL-1 accelerates thrombolysis and prevents reocclusion in a porcine model
KUMAR, A, VILLANI, M. P, PATEL, U. K, KEITH, J. C, SCHAUB, R. G
Published in Circulation (New York, N.Y.) (16.03.1999)
Published in Circulation (New York, N.Y.) (16.03.1999)
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ARC15105 Is a Potent Antagonist of Von Willebrand Factor Mediated Platelet Activation and Adhesion
Siller-Matula, Jolanta M, Merhi, Yahye, Tanguay, Jean-François, Duerschmied, Daniel, Wagner, Denisa D, McGinness, Kathleen E, Pendergrast, P Shannon, Chung, Jou-Ku, Tian, Xianbin, Schaub, Robert G, Jilma, Bernd
Published in Arteriosclerosis, thrombosis, and vascular biology (01.04.2012)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.04.2012)
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Interleukin 11 significantly increases plasma von Willebrand factor and factor VIII in wild type and von Willebrand disease mouse models
Denis, Cécile V., Kwack, Kyubum, Saffaripour, Simin, Maganti, Srinivas, André, Patrick, Schaub, Robert G., Wagner, Denisa D.
Published in Blood (15.01.2001)
Published in Blood (15.01.2001)
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Interaction of P-selectin and PSGL-1 generates microparticles that correct hemostasis in a mouse model of hemophilia A
Wagner, Denisa D, Hrachovinová, Ingrid, Cambien, Beatrice, Hafezi-Moghadam, Ali, Kappelmayer, János, Camphausen, Raymond T, Widom, Angela, Xia, Lijun, Kazazian, Haig H, Schaub, Robert G, McEver, Rodger P
Published in Nature medicine (01.08.2003)
Published in Nature medicine (01.08.2003)
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Recombinant soluble P-selectin glycoprotein ligand-Ig (rPSGL-Ig) attenuates infarct size and myeloperoxidase activity in a canine model of ischemia-reperfusion
Wang, Kai, Zhou, Xiaorong, Zhou, Zhongmin, Tarakji, Khaldoun, Qin, Jian Xin, Sitges, Marta, Shiota, Takahiro, Forudi, Farhad, Schaub, Robert G, Kumar, Anjali, Penn, Marc S, Topol, Eric J, Lincoff, A Michael
Published in Thrombosis and haemostasis (01.07.2002)
Published in Thrombosis and haemostasis (01.07.2002)
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P-selectin and leukocyte microparticles are associated with venous thrombogenesis
Myers, Daniel D., Hawley, Angela E., Farris, Diana M., Wrobleski, Shirley K., Thanaporn, Porama, Schaub, Robert G., Wagner, Denisa D., Kumar, Anjali, Wakefield, Thomas W.
Published in Journal of vascular surgery (01.11.2003)
Published in Journal of vascular surgery (01.11.2003)
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