Discovery of an Active RAG Transposon Illuminates the Origins of V(D)J Recombination
Huang, Shengfeng, Tao, Xin, Yuan, Shaochun, Zhang, Yuhang, Li, Peiyi, Beilinson, Helen A., Zhang, Ya, Yu, Wenjuan, Pontarotti, Pierre, Escriva, Hector, Le Petillon, Yann, Liu, Xiaolong, Chen, Shangwu, Schatz, David G., Xu, Anlong
Published in Cell (30.06.2016)
Published in Cell (30.06.2016)
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Journal Article
Structural basis of mismatch recognition by a SARS-CoV-2 proofreading enzyme
Liu, Chang, Shi, Wei, Becker, Scott T, Schatz, David G, Liu, Bin, Yang, Yang
Published in Science (03.09.2021)
Published in Science (03.09.2021)
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Structural insights into the evolution of the RAG recombinase
Liu, Chang, Zhang, Yuhang, Liu, Catherine C, Schatz, David G
Published in Nature reviews. Immunology (01.06.2022)
Published in Nature reviews. Immunology (01.06.2022)
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Journal Article
Transposon molecular domestication and the evolution of the RAG recombinase
Zhang, Yuhang, Cheng, Tat Cheung, Huang, Guangrui, Lu, Qingyi, Surleac, Marius D, Mandell, Jeffrey D, Pontarotti, Pierre, Petrescu, Andrei J, Xu, Anlong, Xiong, Yong, Schatz, David G
Published in Nature (London) (01.05.2019)
Published in Nature (London) (01.05.2019)
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Journal Article
Chromosomal Loop Domains Direct the Recombination of Antigen Receptor Genes
Hu, Jiazhi, Zhang, Yu, Zhao, Lijuan, Frock, Richard L., Du, Zhou, Meyers, Robin M., Meng, Fei-long, Schatz, David G., Alt, Frederick W.
Published in Cell (05.11.2015)
Published in Cell (05.11.2015)
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Journal Article
RAG2 abolishes RAG1 aggregation to facilitate V(D)J recombination
Gan, Tingting, Wang, Yuhong, Liu, Yang, Schatz, David G., Hu, Jiazhi
Published in Cell reports (Cambridge) (12.10.2021)
Published in Cell reports (Cambridge) (12.10.2021)
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Journal Article
The In Vivo Pattern of Binding of RAG1 and RAG2 to Antigen Receptor Loci
Ji, Yanhong, Resch, Wolfgang, Corbett, Elizabeth, Yamane, Arito, Casellas, Rafael, Schatz, David G.
Published in Cell (30.04.2010)
Published in Cell (30.04.2010)
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Journal Article
RAG Represents a Widespread Threat to the Lymphocyte Genome
Teng, Grace, Maman, Yaakov, Resch, Wolfgang, Kim, Min, Yamane, Arito, Qian, Jason, Kieffer-Kwon, Kyong-Rim, Mandal, Malay, Ji, Yanhong, Meffre, Eric, Clark, Marcus R., Cowell, Lindsay G., Casellas, Rafael, Schatz, David G.
Published in Cell (13.08.2015)
Published in Cell (13.08.2015)
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Journal Article
Collaboration of RAG2 with RAG1-like proteins during the evolution of V(D)J recombination
Carmona, Lina Marcela, Fugmann, Sebastian D, Schatz, David G
Published in Genes & development (15.04.2016)
Published in Genes & development (15.04.2016)
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Journal Article
Structural basis for the activation and suppression of transposition during evolution of the RAG recombinase
Zhang, Yuhang, Corbett, Elizabeth, Wu, Shenping, Schatz, David G
Published in The EMBO journal (02.11.2020)
Published in The EMBO journal (02.11.2020)
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Journal Article
Mechanisms of clonal evolution in childhood acute lymphoblastic leukemia
Swaminathan, Srividya, Klemm, Lars, Park, Eugene, Papaemmanuil, Elli, Ford, Anthony, Kweon, Soo-Mi, Trageser, Daniel, Hasselfeld, Brian, Henke, Nadine, Mooster, Jana, Geng, Huimin, Schwarz, Klaus, Kogan, Scott C, Casellas, Rafael, Schatz, David G, Lieber, Michael R, Greaves, Mel F, Müschen, Markus
Published in Nature immunology (01.07.2015)
Published in Nature immunology (01.07.2015)
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