Mast Cells in Alveolar Septa of COVID-19 Patients: A Pathogenic Pathway That May Link Interstitial Edema to Immunothrombosis
Motta Junior, Jarbas da Silva, Miggiolaro, Anna Flavia Ribeiro Dos Santos, Nagashima, Seigo, de Paula, Caroline Busatta Vaz, Baena, Cristina Pellegrino, Scharfstein, Julio, de Noronha, Lucia
Published in Frontiers in immunology (18.09.2020)
Published in Frontiers in immunology (18.09.2020)
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Pleiotropic antifibrotic actions of aspirin-triggered resolvin D1 in the lungs
Guilherme, Rafael F, Silva, José Bruno N F, Waclawiack, Ingrid, Fraga-Junior, Vanderlei S, Nogueira, Thaís O, Pecli, Cyntia, Araújo-Silva, Carlla A, Magalhães, Nathalia S, Lemos, Felipe S, Bulant, Carlos A, Blanco, Pablo J, Serra, Rafaela, Svensjö, Erik, Scharfstein, Júlio, Moraes, João A, Canetti, Claudio, Benjamim, Claudia F
Published in Frontiers in immunology (07.03.2023)
Published in Frontiers in immunology (07.03.2023)
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P2Y14 Receptor as a Target for Neutrophilia Attenuation in Severe COVID-19 Cases: From Hematopoietic Stem Cell Recruitment and Chemotaxis to Thrombo‐inflammation
Lintzmaier Petiz, Lyvia, Glaser, Talita, Scharfstein, Julio, Ratajczak, Mariusz Z., Ulrich, Henning
Published in Stem cell reviews and reports (01.02.2021)
Published in Stem cell reviews and reports (01.02.2021)
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Contact System Activation in Plasma from Dengue Patients Might Harness Endothelial Virus Replication through the Signaling of Bradykinin Receptors
Coelho, Sharton V A, Rust, Naiara M, Vellasco, Lucas, Papa, Michelle P, Pereira, Aline S G, Silva Palazzo, Matheus Ferreira da, Juliano, Maria Aparecida, Costa, Simone M, Alves, Ada M B, Cordeiro, Marli T, Marques, Ernesto T A, Scharfstein, Júlio, Arruda, Luciana B de
Published in Pharmaceuticals (Basel, Switzerland) (12.01.2021)
Published in Pharmaceuticals (Basel, Switzerland) (12.01.2021)
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High mobility group box 1, ATP, lipid mediators, and tissue factor are elevated in COVID‐19 patients: HMGB1 as a biomarker of worst prognosis
Vicentino, Amanda Roberta Revoredo, Fraga‐Junior, Vanderlei da Silva, Palazzo, Matheus, Tasmo, Natalia Recardo Amorim, Rodrigues, Danielle A. S., Barroso, Shana Priscila Coutinho, Ferreira, Sâmila Natiane, Neves‐Borges, Anna Cristina, Allonso, Diego, Fantappié, Marcelo Rosado, Scharfstein, Julio, Oliveira, Ana Carolina, Vianna‐Jorge, Rosane, Vale, André Macedo, Coutinho‐Silva, Robson, Savio, Luiz Eduardo Baggio, Canetti, Claudio, Benjamim, Claudia Farias
Published in Clinical and translational science (01.04.2023)
Published in Clinical and translational science (01.04.2023)
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Novel Family of Insect Salivary Inhibitors Blocks Contact Pathway Activation by Binding to Polyphosphate, Heparin, and Dextran Sulfate
Alvarenga, Patricia H, Xu, Xueqing, Oliveira, Fabiano, Chagas, Andrezza C, Nascimento, Clarissa R, Francischetti, Ivo M.B, Juliano, Maria A, Juliano, Luiz, Scharfstein, Julio, Valenzuela, Jesus G, Ribeiro, José M.C, Andersen, John F
Published in Arteriosclerosis, thrombosis, and vascular biology (01.12.2013)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.12.2013)
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Mast Cell Coupling to the Kallikrein-Kinin System Fuels Intracardiac Parasitism and Worsens Heart Pathology in Experimental Chagas Disease
Nascimento, Clarissa R, Andrade, Daniele, Carvalho-Pinto, Carla Eponina, Serra, Rafaela Rangel, Vellasco, Lucas, Brasil, Guilherme, Ramos-Junior, Erivan Schnaider, da Mota, Julia Barbalho, Almeida, Larissa Nogueira, Andrade, Marcus V, Correia Soeiro, Maria de Nazaré, Juliano, Luiz, Alvarenga, Patrícia Hessab, Oliveira, Ana Carolina, Sicuro, Fernando Lencastre, de Carvalho, Antônio C Campos, Svensjö, Erik, Scharfstein, Julio
Published in Frontiers in immunology (02.08.2017)
Published in Frontiers in immunology (02.08.2017)
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Bradykinin B2 Receptors of dendritic cells, acting as sensors of kinins proteolytically released by Trypanosoma cruzi, are critical for the development of protective type-1 responses
Monteiro, Ana Carolina, Schmitz, Verônica, Morrot, Alexandre, de Arruda, Luciana Barros, Nagajyothi, Fnu, Granato, Alessandra, Pesquero, João B, Müller-Esterl, Werner, Tanowitz, Herbert B, Scharfstein, Julio
Published in PLoS pathogens (01.11.2007)
Published in PLoS pathogens (01.11.2007)
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Proteolytic generation of kinins in tissues infected by Trypanosoma cruzi depends on CXC chemokine secretion by macrophages activated via Toll-like 2 receptors
Schmitz, Veronica, Svensjö, Erik, Serra, Rafaela Rangel, Teixeira, Mauro M., Scharfstein, Julio
Published in Journal of leukocyte biology (01.06.2009)
Published in Journal of leukocyte biology (01.06.2009)
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Ecotin-Like ISP of L. major Promastigotes Fine-Tunes Macrophage Phagocytosis by Limiting the Pericellular Release of Bradykinin from Surface-Bound Kininogens: A Survival Strategy Based on the Silencing of Proinflammatory G-Protein Coupled Kinin B2 and B1 Receptors
Juliano, Luiz, Vellasco, Lucas, Nogueira de Almeida, Larissa, Svensjö, Erik, Scharfstein, Julio
Published in Mediators of inflammation (2014)
Published in Mediators of inflammation (2014)
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Sheltered in Stromal Tissue Cells, Trypanosoma cruzi Orchestrates Inflammatory Neovascularization via Activation of the Mast Cell Chymase Pathway
Vellasco, Lucas, Svensjö, Erik, Bulant, Carlos Alberto, Blanco, Pablo Javier, Nogueira, Fábio, Domont, Gilberto, de Almeida, Natália Pinto, Nascimento, Clarissa Rodrigues, Silva-Dos-Santos, Danielle, Carvalho-Pinto, Carla Eponina, Medei, Emiliano Horácio, Almeida, Igor C, Scharfstein, Julio
Published in Pathogens (Basel) (29.01.2022)
Published in Pathogens (Basel) (29.01.2022)
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Kinins Released by Erythrocytic Stages of Plasmodium falciparum Enhance Adhesion of Infected Erythrocytes to Endothelial Cells and Increase Blood Brain Barrier Permeability via Activation of Bradykinin Receptors
Silva, Leandro S, Pinheiro, Alessandro S, Teixeira, Douglas E, Silva-Aguiar, Rodrigo P, Peruchetti, Diogo B, Scharfstein, Julio, Caruso-Neves, Celso, Pinheiro, Ana Acacia S
Published in Frontiers in medicine (16.04.2019)
Published in Frontiers in medicine (16.04.2019)
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Journal Article
Ecotin-Like ISP of L. major Promastigotes Fine-Tunes Macrophage Phagocytosis by Limiting the Pericellular Release of Bradykinin from Surface-Bound Kininogens: A Survival Strategy Based on the Silencing of Proinflammatory G-Protein Coupled Kinin B_2 and B_1 Receptors
Svensjö, Erik, Nogueira de Almeida, Larissa, Vellasco, Lucas, Juliano, Luiz, Scharfstein, Julio
Published in Mediators of Inflammation (01.01.2014)
Published in Mediators of Inflammation (01.01.2014)
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Protease activated receptor signaling is required for African trypanosome traversal of human brain microvascular endothelial cells
Grab, Dennis J, Garcia-Garcia, Jose C, Nikolskaia, Olga V, Kim, Yuri V, Brown, Amanda, Pardo, Carlos A, Zhang, Yongqing, Becker, Kevin G, Wilson, Brenda A, de A Lima, Ana Paula C, Scharfstein, Julio, Dumler, J Stephen
Published in PLoS neglected tropical diseases (21.07.2009)
Published in PLoS neglected tropical diseases (21.07.2009)
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Maxadilan, the Lutzomyia longipalpis vasodilator, drives plasma leakage via PAC1–CXCR1/2-pathway
Svensjö, Erik, Saraiva, Elvira M., Amendola, Rafael Silveira, Barja-Fidalgo, Christina, Bozza, Marcelo T., Lerner, Ethan A., Teixeira, Mauro M., Scharfstein, Julio
Published in Microvascular research (01.03.2012)
Published in Microvascular research (01.03.2012)
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Perspectives on the Trypanosoma cruzi-host cell receptor interactions
Villalta, Fernando, Scharfstein, Julio, Ashton, Anthony W, Tyler, Kevin M, Guan, Fangxia, Mukherjee, Shankar, Lima, Maria F, Alvarez, Sandra, Weiss, Louis M, Huang, Huan, Machado, Fabiana S, Tanowitz, Herbert B
Published in Parasitology research (1987) (01.06.2009)
Published in Parasitology research (1987) (01.06.2009)
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