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Published in Diabetes (New York, N.Y.) (01.05.2019)
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Development of a conditionally immortalized human pancreatic β cell line
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Published in The Journal of clinical investigation (01.05.2014)
Published in The Journal of clinical investigation (01.05.2014)
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Efficient Generation of Glucose-Responsive Beta Cells from Isolated GP2+ Human Pancreatic Progenitors
Ameri, Jacqueline, Borup, Rehannah, Prawiro, Christy, Ramond, Cyrille, Schachter, Karen A., Scharfmann, Raphael, Semb, Henrik
Published in Cell reports (Cambridge) (04.04.2017)
Published in Cell reports (Cambridge) (04.04.2017)
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Regulated expression and function of the GABAB receptor in human pancreatic beta cell line and islets
Rachdi, Latif, Maugein, Alicia, Pechberty, Severine, Armanet, Mathieu, Hamroune, Juliette, Ravassard, Philippe, Marullo, Stefano, Albagli, Olivier, Scharfmann, Raphael
Published in Scientific reports (10.08.2020)
Published in Scientific reports (10.08.2020)
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Mitochondrial Protein UCP2 Controls Pancreas Development
Broche, Benjamin, Ben Fradj, Selma, Aguilar, Esther, Sancerni, Tiphaine, Bénard, Matthieu, Makaci, Fatna, Berthault, Claire, Scharfmann, Raphaël, Alves-Guerra, Marie-Clotilde, Duvillié, Bertrand
Published in Diabetes (New York, N.Y.) (01.01.2018)
Published in Diabetes (New York, N.Y.) (01.01.2018)
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A 3D atlas of the human developing pancreas to explore progenitor proliferation and differentiation
Villalba, Adrian, Gitton, Yorick, Inoue, Megumi, Aiello, Virginie, Blain, Raphaël, Toupin, Maryne, Mazaud-Guittot, Séverine, Rachdi, Latif, Semb, Henrik, Chédotal, Alain, Scharfmann, Raphaël
Published in Diabetologia (01.06.2024)
Published in Diabetologia (01.06.2024)
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Functional genetics reveals the contribution of delta opioid receptor to type 2 diabetes and beta-cell function
Meulebrouck, Sarah, Merrheim, Judith, Queniat, Gurvan, Bourouh, Cyril, Derhourhi, Mehdi, Boissel, Mathilde, Yi, Xiaoyan, Badreddine, Alaa, Boutry, Raphaël, Leloire, Audrey, Toussaint, Bénédicte, Amanzougarene, Souhila, Vaillant, Emmanuel, Durand, Emmanuelle, Loiselle, Hélène, Huyvaert, Marlène, Dechaume, Aurélie, Scherrer, Victoria, Marchetti, Piero, Balkau, Beverley, Charpentier, Guillaume, Franc, Sylvia, Marre, Michel, Roussel, Ronan, Scharfmann, Raphaël, Cnop, Miriam, Canouil, Mickaël, Baron, Morgane, Froguel, Philippe, Bonnefond, Amélie
Published in Nature communications (05.08.2024)
Published in Nature communications (05.08.2024)
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Mutations in BOREALIN cause thyroid dysgenesis
Carré, Aurore, Stoupa, Athanasia, Kariyawasam, Dulanjalee, Gueriouz, Manelle, Ramond, Cyrille, Monus, Taylor, Léger, Juliane, Gaujoux, Sébastien, Sebag, Frédéric, Glaser, Nicolas, Zenaty, Delphine, Nitschke, Patrick, Bole-Feysot, Christine, Hubert, Laurence, Lyonnet, Stanislas, Scharfmann, Raphaël, Munnich, Arnold, Besmond, Claude, Taylor, William, Polak, Michel
Published in Human molecular genetics (01.02.2017)
Published in Human molecular genetics (01.02.2017)
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Systematic Functional Characterization of Candidate Causal Genes for Type 2 Diabetes Risk Variants
Thomsen, Soren K, Ceroni, Alessandro, van de Bunt, Martijn, Burrows, Carla, Barrett, Amy, Scharfmann, Raphael, Ebner, Daniel, McCarthy, Mark I, Gloyn, Anna L
Published in Diabetes (New York, N.Y.) (01.12.2016)
Published in Diabetes (New York, N.Y.) (01.12.2016)
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Loss-of-function mutations in MRAP2 are pathogenic in hyperphagic obesity with hyperglycemia and hypertension
Baron, Morgane, Maillet, Julie, Huyvaert, Marlène, Dechaume, Aurélie, Boutry, Raphaël, Loiselle, Hélène, Durand, Emmanuelle, Toussaint, Bénédicte, Vaillant, Emmanuel, Philippe, Julien, Thomas, Jérémy, Ghulam, Amjad, Franc, Sylvia, Charpentier, Guillaume, Borys, Jean-Michel, Lévy-Marchal, Claire, Tauber, Maïthé, Scharfmann, Raphaël, Weill, Jacques, Aubert, Cécile, Kerr-Conte, Julie, Pattou, François, Roussel, Ronan, Balkau, Beverley, Marre, Michel, Boissel, Mathilde, Derhourhi, Mehdi, Gaget, Stefan, Canouil, Mickaël, Froguel, Philippe, Bonnefond, Amélie
Published in Nature Medicine (01.11.2019)
Published in Nature Medicine (01.11.2019)
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The RB gene family controls the maturation state of the EndoC-βH2 human pancreatic β-cells
Maugein, Alicia, Diedisheim, Marc, Bailly, Karine, Scharfmann, Raphaël, Albagli, Olivier
Published in Differentiation (London) (01.05.2020)
Published in Differentiation (London) (01.05.2020)
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Understanding human fetal pancreas development using subpopulation sorting, RNA sequencing and single-cell profiling
Ramond, Cyrille, Beydag-Tasöz, Belin Selcen, Azad, Ajuna, van de Bunt, Martijn, Petersen, Maja Borup Kjær, Beer, Nicola L, Glaser, Nicolas, Berthault, Claire, Gloyn, Anna L, Hansson, Mattias, McCarthy, Mark I, Honoré, Christian, Grapin-Botton, Anne, Scharfmann, Raphael
Published in Development (Cambridge) (15.08.2018)
Published in Development (Cambridge) (15.08.2018)
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TUBB1 mutations cause thyroid dysgenesis associated with abnormal platelet physiology
Stoupa, Athanasia, Adam, Frédéric, Kariyawasam, Dulanjalee, Strassel, Catherine, Gawade, Sanjay, Szinnai, Gabor, Kauskot, Alexandre, Lasne, Dominique, Janke, Carsten, Natarajan, Kathiresan, Schmitt, Alain, Bole‐Feysot, Christine, Nitschke, Patrick, Léger, Juliane, Jabot‐Hanin, Fabienne, Tores, Frédéric, Michel, Anita, Munnich, Arnold, Besmond, Claude, Scharfmann, Raphaël, Lanza, François, Borgel, Delphine, Polak, Michel, Carré, Aurore
Published in EMBO molecular medicine (01.12.2018)
Published in EMBO molecular medicine (01.12.2018)
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L-Leucine Alters Pancreatic β-Cell Differentiation and Function via the mTor Signaling Pathway
RACHDI, Latif, AIELLO, Virginie, DUVILLIE, Bertrand, SCHARFMANN, Raphael
Published in Diabetes (New York, N.Y.) (01.02.2012)
Published in Diabetes (New York, N.Y.) (01.02.2012)
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MicroRNA-124a Regulates Foxa2 Expression and Intracellular Signaling in Pancreatic β-Cell Lines
Baroukh, Nadine, Ravier, Magalie A., Loder, Merewyn K., Hill, Elaine V., Bounacer, Ali, Scharfmann, Raphaël, Rutter, Guy A., Van Obberghen, Emmanuel
Published in The Journal of biological chemistry (06.07.2007)
Published in The Journal of biological chemistry (06.07.2007)
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Specific control of pancreatic endocrine β- and δ-cell mass by class IIa histone deacetylases HDAC4, HDAC5, and HDAC9
Lenoir, Olivia, Flosseau, Kathleen, Ma, Feng Xia, Blondeau, Bertrand, Mai, Antonello, Bassel-Duby, Rhonda, Ravassard, Philippe, Olson, Eric N, Haumaitre, Cécile, Scharfmann, Raphaël
Published in Diabetes (New York, N.Y.) (01.11.2011)
Published in Diabetes (New York, N.Y.) (01.11.2011)
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