Mechanism of mitochondrial permeability transition pore induction and damage in the pancreas: inhibition prevents acute pancreatitis by protecting production of ATP
Mukherjee, Rajarshi, Mareninova, Olga A, Odinokova, Irina V, Huang, Wei, Murphy, John, Chvanov, Michael, Javed, Muhammad A, Wen, Li, Booth, David M, Cane, Matthew C, Awais, Muhammad, Gavillet, Bruno, Pruss, Rebecca M, Schaller, Sophie, Molkentin, Jeffery D, Tepikin, Alexei V, Petersen, Ole H, Pandol, Stephen J, Gukovsky, Ilya, Criddle, David N, Gukovskaya, Anna S, Sutton, Robert
Published in Gut (01.08.2016)
Published in Gut (01.08.2016)
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Characterization of osteoclasts derived from CD14+ monocytes isolated from peripheral blood
SØRENSEN, Mette Grøndahl, HENRIKSEN, Kim, SCHALLER, Sophie, HENRIKSEN, Dennis Bang, NIELSEN, Finn Cilius, DZIEGIEL, Morten Hanefeld, KARSDAL, Morten Asser
Published in Journal of bone and mineral metabolism (01.01.2007)
Published in Journal of bone and mineral metabolism (01.01.2007)
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Characterization of Osteoclasts from Patients Harboring a G215R Mutation in ClC-7 Causing Autosomal Dominant Osteopetrosis Type II
Henriksen, Kim, Gram, Jeppe, Schaller, Sophie, Dahl, Bjarne H., Dziegiel, Morten H., Bollerslev, Jens, Karsdal, Morten A.
Published in The American journal of pathology (01.05.2004)
Published in The American journal of pathology (01.05.2004)
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Degradation of the Organic Phase of Bone by Osteoclasts: A Secondary Role for Lysosomal Acidification
Henriksen, Kim, Sørensen, Mette G, Nielsen, Rasmus H, Gram, Jeppe, Schaller, Sophie, Dziegiel, Morten H, Everts, Vincent, Bollerslev, Jens, Karsdal, Morten A
Published in Journal of bone and mineral research (01.01.2006)
Published in Journal of bone and mineral research (01.01.2006)
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The Chloride Channel Inhibitor NS3736 Prevents Bone Resorption in Ovariectomized Rats Without Changing Bone Formation
Schaller, Sophie, Henriksen, Kim, Sveigaard, Christina, Heegaard, Anne‐Marie, Hélix, Nathalie, Stahlhut, Martin, Ovejero, Maria C, Johansen, Jens V, Solberg, Helene, Andersen, Thomas L, Hougaard, Dorit, Berryman, Mark, Shiødt, Christine B, Sørensen, Bjørn H, Lichtenberg, Jens, Christophersen, Palle, Foged, Niels T, Delaissé, Jean‐Marie, Engsig, Michael T, Karsdal, Morten A
Published in Journal of bone and mineral research (01.07.2004)
Published in Journal of bone and mineral research (01.07.2004)
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Effect of intravenous TRO40303 as an adjunct to primary percutaneous coronary intervention for acute ST-elevation myocardial infarction: MITOCARE study results
Atar, Dan, Arheden, Håkan, Berdeaux, Alain, Bonnet, Jean-Louis, Carlsson, Marcus, Clemmensen, Peter, Cuvier, Valérie, Danchin, Nicolas, Dubois-Randé, Jean-Luc, Engblom, Henrik, Erlinge, David, Firat, Hüseyin, Halvorsen, Sigrun, Hansen, Henrik Steen, Hauke, Wilfried, Heiberg, Einar, Koul, Sasha, Larsen, Alf-Inge, Le Corvoisier, Philippe, Nordrehaug, Jan Erik, Paganelli, Franck, Pruss, Rebecca M, Rousseau, Hélène, Schaller, Sophie, Sonou, Giles, Tuseth, Vegard, Veys, Julien, Vicaut, Eric, Jensen, Svend Eggert
Published in European heart journal (07.01.2015)
Published in European heart journal (07.01.2015)
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TRO40303 Ameliorates Alcohol-Induced Pancreatitis Through Reduction of Fatty Acid Ethyl Ester-Induced Mitochondrial Injury and Necrotic Cell Death
Javed, Muhammad Ahsan, Wen, Li, Awais, Muhammad, Latawiec, Diane, Huang, Wei, Chvanov, Michael, Schaller, Sophie, Bordet, Thierry, Michaud, Magali, Pruss, Rebecca, Tepikin, Alexei, Criddle, David, Sutton, Robert
Published in Pancreas (01.01.2018)
Published in Pancreas (01.01.2018)
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TRO40303, a new cardioprotective compound, inhibits mitochondrial permeability transition
Schaller, Sophie, Paradis, Stéphanie, Ngoh, Gladys A, Assaly, Rana, Buisson, Bruno, Drouot, Cyrille, Ostuni, Mariano A, Lacapere, Jean-Jacques, Bassissi, Firas, Bordet, Thierry, Berdeaux, Alain, Jones, Steven P, Morin, Didier, Pruss, Rebecca M
Published in The Journal of pharmacology and experimental therapeutics (01.06.2010)
Published in The Journal of pharmacology and experimental therapeutics (01.06.2010)
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Journal Article
Differences in the profile of protection afforded by TRO40303 and mild hypothermia in models of cardiac ischemia/reperfusion injury
Hansson, Magnus J., Llwyd, Osian, Morin, Didier, de Paulis, Damien, Arnoux, Thomas, Gouarné, Caroline, Koul, Sasha, Engblom, Henrik, Bordet, Thierry, Tissier, Renaud, Arheden, Haakan, Erlinge, David, Halestrap, Andrew P., Berdeaux, Alain, Pruss, Rebecca M., Schaller, Sophie
Published in European journal of pharmacology (05.08.2015)
Published in European journal of pharmacology (05.08.2015)
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Mitochondrial translocator protein (TSPO) ligands prevent doxorubicin-induced mechanical dysfunction and cell death in isolated cardiomyocytes
de Tassigny, Alexandra d'Anglemont, Assaly, Rana, Schaller, Sophie, Pruss, Rebecca M, Berdeaux, Alain, Morin, Didier
Published in Mitochondrion (01.11.2013)
Published in Mitochondrion (01.11.2013)
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Translation of TRO40303 from myocardial infarction models to demonstration of safety and tolerance in a randomized Phase I trial
Le Lamer, Sophie, Paradis, Stéphanie, Rahmouni, Hidayat, Chaimbault, Corinne, Michaud, Magali, Culcasi, Marcel, Afxantidis, Jean, Latreille, Mathilde, Berna, Patrick, Berdeaux, Alain, Pietri, Sylvia, Morin, Didier, Donazzolo, Yves, Abitbol, Jean-Louis, Pruss, Rebacca M, Schaller, Sophie
Published in Journal of translational medicine (07.02.2014)
Published in Journal of translational medicine (07.02.2014)
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Journal Article
Acidification of the Osteoclastic Resorption Compartment Provides Insight into the Coupling of Bone Formation to Bone Resorption
Karsdal, Morten A., Henriksen, Kim, Sørensen, Mette G., Gram, Jeppe, Schaller, Sophie, Dziegiel, Morten H., Heegaard, Anne-Marie, Christophersen, Palle, Martin, Thomas J., Christiansen, Claus, Bollerslev, Jens
Published in The American journal of pathology (01.02.2005)
Published in The American journal of pathology (01.02.2005)
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Journal Article
Rationale and Design of the ‘MITOCARE’ Study: A Phase II, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Assess the Safety and Efficacy of TRO40303 for the Reduction of Reperfusion Injury in Patients Undergoing Percutaneous Coronary Intervention for Acute Myocardial Infarction
Atar, Dan, Abitbol, Jean-Louis, Arheden, Håkan, Berdeaux, Alain, Bonnet, Jean-Louis, Carlsson, Marcus, Clemmensen, Peter, Cuvier, Valerie, Danchin, Nicolas, Dubois-Rande, Jean-Luc, Engblom, Henrik, Erlinge, David, Firat, Huseyin, Jensen, Svend Eggert, Halvorsen, Sigrun, Hansen, Henrik Steen, Heiberg, Einar, Larsen, Alf-Inge, Le Corvoisier, Philippe, Longlade, Pascal, Nordrehaug, Jan Erik, Perez, Carole, Pruss, Rebecca, Sonou, Gilles, Schaller, Sophie, Tuseth, Vegard, Vicaut, Eric
Published in Cardiology (01.01.2012)
Published in Cardiology (01.01.2012)
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Journal Article
The chloride channel inhibitor N53736 prevents bone resorption in ovariectomized rats without changing bone formation
SCHALLER, Sophie, HENRIKSEN, Kim, HOUGAARD, Dorit, BERRYMAN, Mark, SHIODT, Christine B, SØRENSEN, Bjørn H, LICHTENBERG, Jens, CHRISTOPHERSEN, Palle, FOGED, Niels T, DELAISSE, Jean-Marie, ENGSIG, Michael T, KARSDAL, Morten A, SVEIGAARD, Christina, HEEGAARD, Anne-Marie, HELIX, Nathalie, STAHLHUT, Martin, OVEJERO, Maria C, JOHANSEN, Jens V, SOLBERG, Helene, ANDERSEN, Thomas L
Published in Journal of bone and mineral research (01.07.2004)
Published in Journal of bone and mineral research (01.07.2004)
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Journal Article
Osteoclasts from Patients with Autosomal Dominant Osteopetrosis Type I Caused by a T253I Mutation in Low-Density Lipoprotein Receptor-Related Protein 5 Are Normal in Vitro, but Have Decreased Resorption Capacity in Vivo
Henriksen, Kim, Gram, Jeppe, Høegh-Andersen, Pernille, Jemtland, Rune, Ueland, Thor, Dziegiel, Morten H., Schaller, Sophie, Bollerslev, Jens, Karsdal, Morten A.
Published in The American journal of pathology (01.11.2005)
Published in The American journal of pathology (01.11.2005)
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Journal Article
TRO40303, a mitochondrial‐targeted cytoprotective compound, provides protection in hepatitis models
Schaller, Sophie, Michaud, Magali, Latyszenok, Virginie, Robert, Fabrice, Hocine, Mélanie, Arnoux, Thomas, Gabriac, Mélanie, Codoul, Hélène, Bourhane, Ahmed, Bellefois, Isabel Clémançon, Afxantidis, Jean, Pruss, Rebecca M.
Published in Pharmacology research & perspectives (01.06.2015)
Published in Pharmacology research & perspectives (01.06.2015)
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Journal Article
TRO 40303, a mitochondrial‐targeted cytoprotective compound, provides protection in hepatitis models
Schaller, Sophie, Michaud, Magali, Latyszenok, Virginie, Robert, Fabrice, Hocine, Mélanie, Arnoux, Thomas, Gabriac, Mélanie, Codoul, Hélène, Bourhane, Ahmed, de Bellefois, Isabel Clémançon, Afxantidis, Jean, Pruss, Rebecca M.
Published in Pharmacology research & perspectives (01.06.2015)
Published in Pharmacology research & perspectives (01.06.2015)
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