Human TLR8 senses UR/URR motifs in bacterial and mitochondrial RNA
Krüger, Anne, Oldenburg, Marina, Chebrolu, Chiranjeevi, Beisser, Daniela, Kolter, Julia, Sigmund, Anna M, Steinmann, Jörg, Schäfer, Simon, Hochrein, Hubertus, Rahmann, Sven, Wagner, Hermann, Henneke, Philipp, Hornung, Veit, Buer, Jan, Kirschning, Carsten J
Published in EMBO reports (01.12.2015)
Published in EMBO reports (01.12.2015)
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Long interspersed nuclear elements safeguard neural progenitors from precocious differentiation
Toda, Tomohisa, Bedrosian, Tracy A., Schafer, Simon T., Cuoco, Michael S., Linker, Sara B., Ghassemzadeh, Saeed, Mitchell, Lisa, Whiteley, Jack T., Novaresi, Nicole, McDonald, Aidan H., Gallina, Iryna S., Yoon, Hyojung, Hester, Mark E., Pena, Monique, Lim, Christina, Suljic, Emelia, AlFatah Mansour, Abed, Boulard, Matthieu, Parylak, Sarah L., Gage, Fred H.
Published in Cell reports (Cambridge) (27.02.2024)
Published in Cell reports (Cambridge) (27.02.2024)
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Real-time detection and differentiation of direct oral anticoagulants (rivaroxaban and dabigatran) using modified thromboelastometric reagents
Schäfer, Simon Thomas, Wiederkehr, Tobias, Kammerer, Tobias, Acevedo, Alice-Christin, Feil, Katharina, Kellert, Lars, Görlinger, Klaus, Hinske, Ludwig Christian, Groene, Philipp
Published in Thrombosis research (01.06.2020)
Published in Thrombosis research (01.06.2020)
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Journal Article
NGLY1 mutations cause protein aggregation in human neurons
Manole, Andreea, Wong, Thomas, Rhee, Amanda, Novak, Sammy, Chin, Shao-Ming, Tsimring, Katya, Paucar, Andres, Williams, April, Newmeyer, Traci Fang, Schafer, Simon T., Rosh, Idan, Kaushik, Susmita, Hoffman, Rene, Chen, Songjie, Wang, Guangwen, Snyder, Michael, Cuervo, Ana Maria, Andrade, Leo, Manor, Uri, Lee, Kevin, Jones, Jeffrey R., Stern, Shani, Marchetto, Maria C., Gage, Fred H.
Published in Cell reports (Cambridge) (26.12.2023)
Published in Cell reports (Cambridge) (26.12.2023)
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AQP5-1364A/C polymorphism and the AQP5 expression influence sepsis survival and immune cell migration: a prospective laboratory and patient study
Rump, Katharina, Unterberg, Matthias, Bergmann, Lars, Bankfalvi, Agnes, Menon, Anil, Schäfer, Simon, Scherag, André, Bazzi, Zainab, Siffert, Winfried, Peters, Jürgen, Adamzik, Michael
Published in Journal of translational medicine (21.11.2016)
Published in Journal of translational medicine (21.11.2016)
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Chemical modulation of transcriptionally enriched signaling pathways to optimize the conversion of fibroblasts into neurons
Herdy, Joseph, Schafer, Simon, Kim, Yongsung, Ansari, Zoya, Zangwill, Dina, Ku, Manching, Paquola, Apua, Lee, Hyungjun, Mertens, Jerome, Gage, Fred H
Published in eLife (17.05.2019)
Published in eLife (17.05.2019)
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REST Regulates Non-Cell-Autonomous Neuronal Differentiation and Maturation of Neural Progenitor Cells via Secretogranin II
Kim, Hyung Joon, Denli, Ahmet M, Wright, Rebecca, Baul, Tithi D, Clemenson, Gregory D, Morcos, Ari S, Zhao, Chunmei, Schafer, Simon T, Gage, Fred H, Kagalwala, Mohamedi N
Published in The Journal of neuroscience (04.11.2015)
Published in The Journal of neuroscience (04.11.2015)
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Dynamic Interrogation of Stochastic Transcriptome Trajectories Using Disease Associated Genes Reveals Distinct Origins of Neurological and Psychiatric Disorders
Bermperidis, Theodoros, Schafer, Simon, Gage, Fred H, Sejnowski, Terrence, Torres, Elizabeth B
Published in Frontiers in neuroscience (02.06.2022)
Published in Frontiers in neuroscience (02.06.2022)
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Targeting B cells in the pre-phase of systemic autoimmunity globally interferes with autoimmune pathology
Werner, Anja, Schäfer, Simon, Zaytseva, Olga, Albert, Heike, Lux, Anja, Krištić, Jasminka, Pezer, Marija, Lauc, Gordan, Winkler, Thomas, Nimmerjahn, Falk
Published in iScience (24.09.2021)
Published in iScience (24.09.2021)
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A New Approach for Air Cargo Network Planning
Derigs, Ulrich, Friederichs, Stefan, Schafer, Simon
Published in Transportation science (01.08.2009)
Published in Transportation science (01.08.2009)
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Improved Method for Efficient Generation of Functional Neurons from Murine Neural Progenitor Cells
Soni, Abhinav, Klütsch, Diana, Hu, Xin, Houtman, Judith, Rund, Nicole, McCloskey, Asako, Mertens, Jerome, Schafer, Simon T, Amin, Hayder, Toda, Tomohisa
Published in Cells (Basel, Switzerland) (26.07.2021)
Published in Cells (Basel, Switzerland) (26.07.2021)
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The NFKB1 Promoter Polymorphism (―94ins/delATTG) Alters Nuclear Translocation of NF-κB1 in Monocytes after Lipopolysaccharide Stimulation and Is Associated with Increased Mortality in Sepsis
ADAMZIK, Michael, SCHAFER, Simon, SIFFERT, Winfried, PETERS, Jürgen, HARTMANN, Matthias, FREY, Ulrich H, BECKER, Arne, KREUZER, Maximiliane, WINNING, Sandra, FREDE, Stilla, STEINMANN, Jörg, FANDREY, Joachim, ZACHAROWSKI, Kai
Published in Anesthesiology (Philadelphia) (2013)
Published in Anesthesiology (Philadelphia) (2013)
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Reduced synaptic activity and dysregulated extracellular matrix pathways in midbrain neurons from Parkinson’s disease patients
Stern, Shani, Lau, Shong, Manole, Andreea, Rosh, Idan, Percia, Menachem Mendel, Ben Ezer, Ran, Shokhirev, Maxim N., Qiu, Fan, Schafer, Simon, Mansour, Abed AlFatah, Mangan, Kile P., Stern, Tchelet, Ofer, Polina, Stern, Yam, Diniz Mendes, Ana Paula, Djamus, Jose, Moore, Lynne Randolph, Nayak, Ritu, Laufer, Sapir Havusha, Aicher, Aidan, Rhee, Amanda, Wong, Thomas L., Nguyen, Thao, Linker, Sara B., Winner, Beate, Freitas, Beatriz C., Jones, Eugenia, Sagi, Irit, Bardy, Cedric, Brice, Alexis, Winkler, Juergen, Marchetto, Maria C., Gage, Fred H.
Published in NPJ Parkinson's Disease (10.08.2022)
Published in NPJ Parkinson's Disease (10.08.2022)
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A Phase 1/2 Single-arm Clinical Trial of Recombinant Bacillus Calmette-Guérin (BCG) VPM1002BC Immunotherapy in Non–muscle-invasive Bladder Cancer Recurrence After Conventional BCG Therapy: SAKK 06/14
Rentsch, Cyrill A., Thalmann, George N., Lucca, Ilaria, Kwiatkowski, Maciej, Wirth, Grégory J., Strebel, Räto T., Engeler, Daniel, Pedrazzini, Augusto, Hüttenbrink, Clemens, Schultze-Seemann, Wolfgang, Torpai, Raimund, Bubendorf, Lukas, Wicki, Andreas, Roth, Beat, Bosshard, Piet, Püschel, Heike, Boll, Daniel T., Hefermehl, Lukas, Roghmann, Florian, Gierth, Michael, Ribi, Karin, Schäfer, Simon, Hayoz, Stefanie
Published in European urology oncology (01.04.2022)
Published in European urology oncology (01.04.2022)
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Erratum: Differential responses to lithium in hyperexcitable neurons from patients with bipolar disorder
Mertens, Jerome, Wang, Qiu-Wen, Kim, Yongsung, Yu, Diana X., Pham, Son, Yang, Bo, Zheng, Yi, Diffenderfer, Kenneth E., Zhang, Jian, Soltani, Sheila, Eames, Tameji, Schafer, Simon T., Boyer, Leah, Marchetto, Maria C., Nurnberger, John I., Calabrese, Joseph R., Oedegaard, Ketil J., McCarthy, Michael J., Zandi, Peter P., Alda, Martin, Nievergelt, Caroline M., Mi, Shuangli, Brennand, Kristen J., Kelsoe, John R., Gage, Fred H., Yao, Jun
Published in Nature (London) (11.02.2016)
Published in Nature (London) (11.02.2016)
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Evidence for Substrate Binding-Induced Zwitterion Formation in the Catalytic Cys-His Dyad of the SARS-CoV Main Protease
Paasche, Alexander, Zipper, Andreas, Schäfer, Simon, Ziebuhr, John, Schirmeister, Tanja, Engels, Bernd
Published in Biochemistry (Easton) (23.09.2014)
Published in Biochemistry (Easton) (23.09.2014)
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Hydrocortisone fails to abolish NF-κB1 protein nuclear translocation in deletion allele carriers of the NFKB1 promoter polymorphism (-94ins/delATTG) and is associated with increased 30-day mortality in septic shock
Schäfer, Simon T, Gessner, Sophia, Scherag, André, Rump, Katharina, Frey, Ulrich H, Siffert, Winfried, Westendorf, Astrid M, Steinmann, Jörg, Peters, Jürgen, Adamzik, Michael
Published in PloS one (18.08.2014)
Published in PloS one (18.08.2014)
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Coagulation under Mild Hypothermia Assessed by Thromboelastometry
Nitschke, Tobias, Groene, Philipp, Acevedo, Alice-Christin, Kammerer, Tobias, Schäfer, Simon T.
Published in Transfusion medicine and hemotherapy (01.08.2021)
Published in Transfusion medicine and hemotherapy (01.08.2021)
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Journal Article
Mitochondrial DNA: An Endogenous Trigger for Immune Paralysis
Schäfer, Simon T, Franken, Lars, Adamzik, Michael, Schumak, Beatrix, Scherag, André, Engler, Andrea, Schönborn, Niels, Walden, Jennifer, Koch, Susanne, Baba, Hideo A, Steinmann, Jörg, Westendorf, Astrid M, Fandrey, Joachim, Bieber, Thomas, Kurts, Christian, Frede, Stilla, Peters, Jürgen, Limmer, Andreas
Published in Anesthesiology (Philadelphia) (01.04.2016)
Published in Anesthesiology (Philadelphia) (01.04.2016)
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