Future treatment options for atopic dermatitis – Small molecules and beyond
Schäkel, Knut, Döbel, Thomas, Bosselmann, Ina
Published in Journal of dermatological science (01.02.2014)
Published in Journal of dermatological science (01.02.2014)
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Journal Article
Controlling the pro-inflammatory function of 6-sulfo LacNAc (slan) dendritic cells with dimethylfumarate
Oehrl, Stephanie, Olaru, Florina, Kunze, Anja, Maas, Michael, Pezer, Silvia, Schmitz, Marc, Schäkel, Knut
Published in Journal of dermatological science (01.09.2017)
Published in Journal of dermatological science (01.09.2017)
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Journal Article
Psoriasis Pathogenesis and Treatment
Rendon, Adriana, Schäkel, Knut
Published in International journal of molecular sciences (23.03.2019)
Published in International journal of molecular sciences (23.03.2019)
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Journal Article
No need to change the drug class: ixekizumab- following secukinumab-therapy in psoriasis
Bokor-Billmann, Therezia, Schäkel, Knut
Published in The Journal of dermatological treatment (03.04.2019)
Published in The Journal of dermatological treatment (03.04.2019)
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Journal Article
The CDK4/6-EZH2 pathway is a potential therapeutic target for psoriasis
Müller, Anne, Dickmanns, Antje, Resch, Claudia, Schäkel, Knut, Hailfinger, Stephan, Dobbelstein, Matthias, Schulze-Osthoff, Klaus, Kramer, Daniela
Published in The Journal of clinical investigation (01.11.2020)
Published in The Journal of clinical investigation (01.11.2020)
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Journal Article
Low-Dose Irradiation Programs Macrophage Differentiation to an iNOS+/M1 Phenotype that Orchestrates Effective T Cell Immunotherapy
Klug, Felix, Prakash, Hridayesh, Huber, Peter E., Seibel, Tobias, Bender, Noemi, Halama, Niels, Pfirschke, Christina, Voss, Ralf Holger, Timke, Carmen, Umansky, Ludmila, Klapproth, Kay, Schäkel, Knut, Garbi, Natalio, Jäger, Dirk, Weitz, Jürgen, Schmitz-Winnenthal, Hubertus, Hämmerling, Günter J., Beckhove, Philipp
Published in Cancer cell (11.11.2013)
Published in Cancer cell (11.11.2013)
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Journal Article
Neutrophil extracellular trap-associated RNA and LL37 enable self-amplifying inflammation in psoriasis
Herster, Franziska, Bittner, Zsofia, Archer, Nathan K., Dickhöfer, Sabine, Eisel, David, Eigenbrod, Tatjana, Knorpp, Thomas, Schneiderhan-Marra, Nicole, Löffler, Markus W., Kalbacher, Hubert, Vierbuchen, Tim, Heine, Holger, Miller, Lloyd S., Hartl, Dominik, Freund, Lukas, Schäkel, Knut, Heister, Martin, Ghoreschi, Kamran, Weber, Alexander N. R.
Published in Nature communications (08.01.2020)
Published in Nature communications (08.01.2020)
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Journal Article
Human slan (6-sulfo LacNAc) dendritic cells are inflammatory dermal dendritic cells in psoriasis and drive strong T 17/T 1 T-cell responses
Hänsel, Anja, Günther, Claudia, Ingwersen, Jens, Starke, Josephine, Schmitz, Marc, Bachmann, Michael, Meurer, Michael, Rieber, Ernst Peter, Schäkel, Knut
Published in Journal of allergy and clinical immunology (01.03.2011)
Published in Journal of allergy and clinical immunology (01.03.2011)
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Journal Article
Skin-Selective CD8 T-Cell Depletion by Photoimmunotherapy Inhibits Human Cutaneous Acute Graft-Versus-Host Disease
Freund, Lukas, Oehrl, Stephanie, Gräbe, Galina, Gholam, Patrick, Plum, Thomas, Schäkel, Knut
Published in Journal of investigative dermatology (01.07.2020)
Published in Journal of investigative dermatology (01.07.2020)
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Journal Article
Current Concepts on 6-sulfo LacNAc Expressing Monocytes (slanMo)
Ahmad, Fareed, Döbel, Thomas, Schmitz, Marc, Schäkel, Knut
Published in Frontiers in immunology (22.05.2019)
Published in Frontiers in immunology (22.05.2019)
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Journal Article
Comparative effectiveness of biologics in clinical practice: week 12 primary outcomes from an international observational psoriasis study of health outcomes (PSoHO)
Pinter, Andreas, Puig, Luis, Schäkel, Knut, Reich, Adam, Zaheri, Shirin, Costanzo, Antonio, Tsai, Tsen Fang, Smith, Saxon D., Lynde, Charles, Brnabic, Alan, Reed, Catherine, Hill, Julie, Schuster, Christopher, Riedl, Elisabeth, Paul, Carle
Published in Journal of the European Academy of Dermatology and Venereology (01.11.2022)
Published in Journal of the European Academy of Dermatology and Venereology (01.11.2022)
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Journal Article
Urticaria: Collegium Internationale Allergologicum (CIA) Update 2020
Maurer, Marcus, Eyerich, Kilian, Eyerich, Stefanie, Ferrer, Marta, Gutermuth, Jan, Hartmann, Karin, Jakob, Thilo, Kapp, Alexander, Kolkhir, Pavel, Larenas-Linnemann, Désirée, Park, Hae-Sim, Pejler, Gunnar, Sánchez-Borges, Mario, Schäkel, Knut, Simon, Dagmar, Simon, Hans-Uwe, Weller, Karsten, Zuberbier, Torsten, Metz, Martin
Published in International archives of allergy and immunology (2020)
Published in International archives of allergy and immunology (2020)
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Journal Article
Guselkumab demonstrates long-term efficacy and maintenance of treatment response postwithdrawal in systemic treatment-naïve patients and nonresponders to fumaric acid esters: results from parts II and III of a randomized active-comparator-controlled phase IIIb trial (POLARIS)
Thaçi, Diamant, Pinter, Andreas, Sebastian, Michael, Termeer, Christian, Sticherling, Michael, Gerdes, Sascha, Schäkel, Knut, Wegner, Sven, Krampe, Stefanie, Bartz, Holger, Rausch, Christian, Taut, Friedemann, Eyerich, Kilian
Published in British journal of dermatology (1951) (20.06.2024)
Published in British journal of dermatology (1951) (20.06.2024)
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Journal Article
IL-4 abrogates T(H)17 cell-mediated inflammation by selective silencing of IL-23 in antigen-presenting cells
Guenova, Emmanuella, Skabytska, Yuliya, Hoetzenecker, Wolfram, Weindl, Günther, Sauer, Karin, Tham, Manuela, Kim, Kyu-Won, Park, Ji-Hyeon, Seo, Ji Hae, Ignatova, Desislava, Cozzio, Antonio, Levesque, Mitchell P, Volz, Thomas, Köberle, Martin, Kaesler, Susanne, Thomas, Peter, Mailhammer, Reinhard, Ghoreschi, Kamran, Schäkel, Knut, Amarov, Boyko, Eichner, Martin, Schaller, Martin, Clark, Rachael A, Röcken, Martin, Biedermann, Tilo
Published in Proceedings of the National Academy of Sciences - PNAS (17.02.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (17.02.2015)
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Journal Article
Formation of keto-type ceramides in palmoplantar keratoderma based on biallelic KDSR mutations in patients
Pilz, Robert, Opálka, Lukáš, Majcher, Adam, Grimm, Elisabeth, Van Maldergem, Lionel, Mihalceanu, Silvia, Schäkel, Knut, Enk, Alexander, Aubin, François, Bursztejn, Anne-Claire, Brischoux-Boucher, Elise, Fischer, Judith, Sandhoff, Roger
Published in Human molecular genetics (31.03.2022)
Published in Human molecular genetics (31.03.2022)
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Journal Article
TH2 Cytokines from Malignant Cells Suppress TH1 Responses and Enforce a Global TH2 Bias in Leukemic Cutaneous T-cell Lymphoma
GUENOVA, Emmanuella, WATANABE, Rei, FISHER, David C, KUPPER, Thomas S, CLARK, Rachael A, TEAGUE, Jessica E, DESIMONE, Jennifer A, YING JIANG, DOWLATSHAHI, Mitra, SCHLAPBACH, Christoph, SCHAEKEL, Knut, ROOK, Alain H, TAWA, Marianne
Published in Clinical cancer research (15.07.2013)
Published in Clinical cancer research (15.07.2013)
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Journal Article
A simple tool for evaluation of inflammation in psoriasis: Neutrophil-to-lymphocyte and platelet-to-lymphocyte ratio as markers in psoriasis patients and related murine models of psoriasis-like skin disease
Kommoss, Katharina S., Bieler, Tabea, Ringen, Julia, Lehmann, Annika, Mihalceanu, Silvia, Hobohm, Lukas, Keller, Karsten, Brand, Anna, Fischer, Berenice, Kramer, Daniela, Wild, Johannes, Waisman, Ari, Enk, Alexander, Schäkel, Knut, Heikenwälder, Mathias, Karbach, Susanne
Published in Journal of molecular medicine (Berlin, Germany) (01.02.2024)
Published in Journal of molecular medicine (Berlin, Germany) (01.02.2024)
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Journal Article
IFNγ Causes Keratinocyte Necroptosis in Acute Graft-Versus-Host Disease
Freund, Lukas, Oehrl, Stephanie, Schwingen, Julius, Haeberle, Stefanie, Döbel, Thomas, Lee, Paul D.H., Meisel, Stefan, Mihalceanu, Silvia, Rußwurm, Martin, Luft, Thomas, Schäkel, Knut
Published in Journal of investigative dermatology (01.09.2023)
Published in Journal of investigative dermatology (01.09.2023)
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Journal Article
Myeloperoxidase Modulates Inflammation in Generalized Pustular Psoriasis and Additional Rare Pustular Skin Diseases
Haskamp, Stefan, Bruns, Heiko, Hahn, Madelaine, Hoffmann, Markus, Gregor, Anne, Löhr, Sabine, Hahn, Jonas, Schauer, Christine, Ringer, Mark, Flamann, Cindy, Frey, Benjamin, Lesner, Adam, Thiel, Christian T., Ekici, Arif B., von Hörsten, Stephan, Aßmann, Gunter, Riepe, Claudia, Euler, Maximilien, Schäkel, Knut, Philipp, Sandra, Prinz, Jörg C., Mößner, Rotraut, Kersting, Florina, Sticherling, Michael, Sefiani, Abdelaziz, Lyahyai, Jaber, Sondermann, Wiebke, Oji, Vinzenz, Schulz, Peter, Wilsmann-Theis, Dagmar, Sticht, Heinrich, Schett, Georg, Reis, André, Uebe, Steffen, Frey, Silke, Hüffmeier, Ulrike
Published in American journal of human genetics (03.09.2020)
Published in American journal of human genetics (03.09.2020)
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