Polymorphisms within novel risk loci for type 2 diabetes determine beta-cell function
Staiger, Harald, Machicao, Fausto, Stefan, Norbert, Tschritter, Otto, Thamer, Claus, Kantartzis, Konstantinos, Schäfer, Silke A, Kirchhoff, Kerstin, Fritsche, Andreas, Häring, Hans-Ulrich
Published in PloS one (05.09.2007)
Published in PloS one (05.09.2007)
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Polymorphisms within the novel type 2 diabetes risk locus MTNR1B determine beta-cell function
Staiger, Harald, Machicao, Fausto, Schäfer, Silke A, Kirchhoff, Kerstin, Kantartzis, Konstantinos, Guthoff, Martina, Silbernagel, Günther, Stefan, Norbert, Häring, Hans-Ulrich, Fritsche, Andreas
Published in PloS one (17.12.2008)
Published in PloS one (17.12.2008)
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Glycemia Determines the Effect of Type 2 Diabetes Risk Genes on Insulin Secretion
HENI, Martin, KETTERER, Caroline, THAMER, Claus, HERZBERG-SCHÄFER, Silke A, GUTHOFF, Martina, STEFAN, Norbert, MACHICAO, Fausto, STAIGER, Harald, FRITSCHE, Andreas, HÄRING, Hans-Ulrich
Published in Diabetes (New York, N.Y.) (01.12.2010)
Published in Diabetes (New York, N.Y.) (01.12.2010)
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Variations in PPARD Determine the Change in Body Composition during Lifestyle Intervention: A Whole-Body Magnetic Resonance Study
Thamer, Claus, Machann, Jürgen, Stefan, Norbert, Schäfer, Silke A, Machicao, Fausto, Staiger, Harald, Laakso, Markku, Böttcher, Michael, Claussen, Claus, Schick, Fritz, Fritsche, Andreas, Haring, Hans-Ulrich
Published in The journal of clinical endocrinology and metabolism (01.04.2008)
Published in The journal of clinical endocrinology and metabolism (01.04.2008)
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Evaluation of fasting state-/oral glucose tolerance test-derived measures of insulin release for the detection of genetically impaired β-cell function
Herzberg-Schäfer, Silke A, Staiger, Harald, Heni, Martin, Ketterer, Caroline, Guthoff, Martina, Kantartzis, Konstantinos, Machicao, Fausto, Stefan, Norbert, Häring, Hans-Ulrich, Fritsche, Andreas
Published in PloS one (02.12.2010)
Published in PloS one (02.12.2010)
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The Inhibitory Effect of Recent Type 2 Diabetes Risk Loci on Insulin Secretion Is Modulated by Insulin Sensitivity
Haupt, Axel, Guthoff, Martina, Schäfer, Silke A, Kirchhoff, Kerstin, Machicao, Fausto, Gallwitz, Baptist, Staiger, Harald, Stefan, Norbert, Fritsche, Andreas, Häring, Hans-Ulrich
Published in The journal of clinical endocrinology and metabolism (01.05.2009)
Published in The journal of clinical endocrinology and metabolism (01.05.2009)
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Journal Article
Novel meta-analysis-derived type 2 diabetes risk loci do not determine prediabetic phenotypes
Staiger, Harald, Machicao, Fausto, Kantartzis, Konstantinos, Schäfer, Silke A, Kirchhoff, Kerstin, Guthoff, Martina, Silbernagel, Günther, Stefan, Norbert, Fritsche, Andreas, Häring, Hans-Ulrich
Published in PloS one (20.08.2008)
Published in PloS one (20.08.2008)
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Journal Article
Association of obesity risk SNPs in PCSK1 with insulin sensitivity and proinsulin conversion
Heni, Martin, Haupt, Axel, Schäfer, Silke A, Ketterer, Caroline, Thamer, Claus, Machicao, Fausto, Stefan, Norbert, Staiger, Harald, Häring, Hans-Ulrich, Fritsche, Andreas
Published in BMC genetics (09.06.2010)
Published in BMC genetics (09.06.2010)
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Cerebrocortical beta activity in overweight humans responds to insulin detemir
Tschritter, Otto, Hennige, Anita M, Preissl, Hubert, Porubska, Katarina, Schäfer, Silke A, Lutzenberger, Werner, Machicao, Fausto, Birbaumer, Niels, Fritsche, Andreas, Häring, Hans-Ulrich
Published in PloS one (21.11.2007)
Published in PloS one (21.11.2007)
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Journal Article
Glucose-raising genetic variants in MADD and ADCY5 impair conversion of proinsulin to insulin
Wagner, Robert, Dudziak, Katarzyna, Herzberg-Schäfer, Silke A, Machicao, Fausto, Stefan, Norbert, Staiger, Harald, Häring, Hans-Ulrich, Fritsche, Andreas
Published in PloS one (22.08.2011)
Published in PloS one (22.08.2011)
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The Impact of Genetic Variation in the G6PC2 Gene on Insulin Secretion Depends on Glycemia
Heni, Martin, Ketterer, Caroline, Hart, Leen M. 't, Ranta, Felicia, van Haeften, Timon W, Eekhoff, Elisabeth M, Dekker, Jacqueline M, Boomsma, Dorret I, Nijpels, Giel, Kramer, Mark H, Diamant, Michaela, Simonis-Bik, Annemarie M, Heine, Robert J, de Geus, Eco J, Schäfer, Silke A, Machicao, Fausto, Ullrich, Susanne, Thamer, Claus, Stefan, Norbert, Staiger, Harald, Häring, Hans-Ulrich, Fritsche, Andreas
Published in The journal of clinical endocrinology and metabolism (01.12.2010)
Published in The journal of clinical endocrinology and metabolism (01.12.2010)
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Polymorphism rs11085226 in the gene encoding polypyrimidine tract-binding protein 1 negatively affects glucose-stimulated insulin secretion
Heni, Martin, Ketterer, Caroline, Wagner, Robert, Linder, Katarzyna, Böhm, Anja, Herzberg-Schäfer, Silke A, Machicao, Fausto, Knoch, Klaus-Peter, Fritsche, Andreas, Staiger, Harald, Häring, Hans-Ulrich, Solimena, Michele
Published in PloS one (15.10.2012)
Published in PloS one (15.10.2012)
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Common polymorphisms within the NR4A3 locus, encoding the orphan nuclear receptor Nor-1, are associated with enhanced beta-cell function in non-diabetic subjects
Weyrich, Peter, Staiger, Harald, Stancáková, Alena, Schäfer, Silke A, Kirchhoff, Kerstin, Ullrich, Susanne, Ranta, Felicia, Gallwitz, Baptist, Stefan, Norbert, Machicao, Fausto, Kuusisto, Johanna, Laakso, Markku, Fritsche, Andreas, Häring, Hans-Ulrich
Published in BMC medical genetics (14.08.2009)
Published in BMC medical genetics (14.08.2009)
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The CTRB1/2 Locus Affects Diabetes Susceptibility and Treatment via the Incretin Pathway
'T HART, Leen M, FRITSCHE, Andreas, PALMER, Colin N. A, VAN HAEFTEN, Timon W, HERZBERG-SCHÄFER, Silke A, SIMONIS-BIK, Annemarie M. C, HOUWING-DUISTERMAAT, Jeanine J, HELMER, Quinta, DEELEN, Joris, GUIGAS, Bruno, HANSEN, Torben, MACHICAO, Fausto, NIJPELS, Giel, WILLEMSEN, Gonneke, HEINE, Robert J, KRAMER, Mark H. H, HOLST, Jens J, DE KONING, Eelco J. P, HÄRING, Hans-Ulrich, PEDERSEN, Oluf, GROOP, Leif, DE GEUS, Eco J. C, SLAGBOOM, P. Eline, VAN LEEUWEN, Nienke, BOOMSMA, Dorret I, EEKHOFF, Elisabeth M. W, PEARSON, Ewan R, DIAMANT, Michaela, DONNELLY, Louise A, DEKKER, Jacqueline M, ALSSEMA, Marjan, FADISTA, Joao, CARLOTTI, Françoise, GJESING, Anette P
Published in Diabetes (New York, N.Y.) (01.09.2013)
Published in Diabetes (New York, N.Y.) (01.09.2013)
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Journal Article
Association of Type 2 Diabetes Candidate Polymorphisms in KCNQ1 With Incretin and Insulin Secretion
MÜSSIG, Karsten, STAIGER, Harald, GALLWITZ, Baptist, HÄRING, Hans-Ulrich, FRITSCHE, Andreas, MACHICAO, Fausto, KIRCHHOFF, Kerstin, GUTHOFF, Martina, SCHÄFER, Silke A, KANTARTZIS, Konstantinos, SILBERNAGEL, Günther, STEFAN, Norbert, HOLST, Jens J
Published in Diabetes (New York, N.Y.) (01.07.2009)
Published in Diabetes (New York, N.Y.) (01.07.2009)
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Combined Risk Allele Score of Eight Type 2 Diabetes Genes Is Associated With Reduced First-Phase Glucose-Stimulated Insulin Secretion During Hyperglycemic Clamps
't Hart, Leen M, Simonis-Bik, Annemarie M, Nijpels, Giel, van Haeften, Timon W, Schäfer, Silke A, Houwing-Duistermaat, Jeanine J, Boomsma, Dorret I, Groenewoud, Marlous J, Reiling, Erwin, van Hove, Els C, Diamant, Michaela, Kramer, Mark H H, Heine, Robert J, Maassen, J Antonie, Kirchhoff, Kerstin, Machicao, Fausto, Häring, Hans-Ulrich, Slagboom, P Eline, Willemsen, Gonneke, Eekhoff, Elisabeth M, de Geus, Eco J, Dekker, Jacqueline M, Fritsche, Andreas
Published in Diabetes (New York, N.Y.) (01.01.2010)
Published in Diabetes (New York, N.Y.) (01.01.2010)
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Preliminary report: genetic variation within the GPBAR1 gene is not associated with metabolic traits in white subjects at an increased risk for type 2 diabetes mellitus
Müssig, Karsten, Staiger, Harald, Machicao, Fausto, Machann, Jürgen, Schick, Fritz, Schäfer, Silke A, Claussen, Claus D, Holst, Jens J, Gallwitz, Baptist, Stefan, Norbert, Fritsche, Andreas, Häring, Hans-Ulrich
Published in Metabolism, clinical and experimental (01.12.2009)
Published in Metabolism, clinical and experimental (01.12.2009)
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Biochemical and morphological effects of K-111, a peroxisome proliferator-activated receptor (PPAR)α activator, in non-human primates
Schäfer, Silke A, Hansen, Barbara C, Völkl, Alfred, Fahimi, H.Dariush, Pill, Johannes
Published in Biochemical pharmacology (15.07.2004)
Published in Biochemical pharmacology (15.07.2004)
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Journal Article
Association of obesity risk SNPs in PCSK1with insulin sensitivity and proinsulin conversion
Heni, Martin, Haupt, Axel, Schäfer, Silke A, Ketterer, Caroline, Thamer, Claus, Machicao, Fausto, Stefan, Norbert, Staiger, Harald, Häring, Hans-Ulrich, Fritsche, Andreas
Published in BMC medical genetics (09.06.2010)
Published in BMC medical genetics (09.06.2010)
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