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Potent and Selective Inhibitors of Platelet-Derived Growth Factor Receptor Phosphorylation. 1. Synthesis, Structure−Activity Relationship, and Biological Effects of a New Class of Quinazoline Derivatives
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Design, synthesis and biological activity of novel non-amidine factor Xa inhibitors. Part 1: P1 Structure-activity relationships of the substituted 1-(2-naphthyl)-1H-pyrazole-5-carboxylamides
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Identification of 4-piperazin-1-yl-quinazoline template based aryl and benzyl thioureas as potent, selective, and orally bioavailable inhibitors of platelet-derived growth factor (PDGF) receptor
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CT53518, a novel selective FLT3 antagonist for the treatment of acute myelogenous leukemia (AML)
Kelly, Louise M, Yu, Jin-Chen, Boulton, Christina L, Apatira, Mutiah, Li, Jason, Sullivan, Carol M, Williams, Ifor, Amaral, Sonia M, Curley, David P, Duclos, Nicole, Neuberg, Donna, Scarborough, Robert M, Pandey, Anjali, Hollenbach, Stanley, Abe, Keith, Lokker, Nathalie A, Gilliland, D.Gary, Giese, Neill A
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Huang, Wenrong, Zhang, Penglie, Zuckett, Jingmei F, Wang, Lingyan, Woolfrey, John, Song, Yonghong, Jia, Zhaozhong J, Clizbe, Lane A, Su, Ting, Tran, Katherine, Huang, Brian, Wong, Paul, Sinha, Uma, Park, Gary, Reed, Andrea, Malinowski, John, Hollenbach, Stanley J, Scarborough, Robert M, Zhu, Bing-Yan
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Antithrombotic and hemostatic capacity of factor Xa versus thrombin inhibitors in models of venous and arteriovenous thrombosis
Sinha, Uma, Ku, Paul, Malinowski, John, Zhu, Bing Yan, Scarborough, Robert M, Marlowe, Charles K, Wong, Paul W, Lin, Pei Hua, Hollenbach, Stanley J
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Published in Bioorganic & medicinal chemistry letters (15.04.2009)
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Design, Synthesis, and Biological Characterization of a Peptide-Mimetic Antagonist for a Tethered-Ligand Receptor
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1-(2-Naphthyl)-1H-pyrazole-5-carboxylamides as potent factor xa inhibitors. Part 3: Design, synthesis and sar of orally bioavailable benzamidine-P4 inhibitors
JIA, Zhaozhong J, YANHONG WU, HOLLENNBACH, Stanley J, LAMBING, Joseph L, SCARBOROUGH, Robert M, ZHU, Bing-Yan, WENRONG HUANG, PENGLIE ZHANG, YONGHONG SONG, WOOLFREY, John, SINHA, Uma, ARFSTEN, Ann E, EDWARDS, Susan T, HUTCHALEELAHA, Athiwat
Published in Bioorganic & medicinal chemistry letters (08.03.2004)
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Ligand Cross-reactivity within the Protease-activated Receptor Family
Blackhart, Brian D., Emilsson, Kjell, Nguyen, Dat, Teng, Willy, Martelli, Arnold J., Nystedt, Sverker, Sundelin, Johan, Scarborough, Robert M.
Published in The Journal of biological chemistry (12.07.1996)
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Published in Journal of medicinal chemistry (29.03.2001)
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