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A Cellular Taxonomy of the Bone Marrow Stroma in Homeostasis and Leukemia
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The bone marrow at the crossroads of blood and immunity
Mercier, Francois E., Ragu, Christine, Scadden, David T.
Published in Nature reviews. Immunology (01.01.2012)
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Cell-state-specific metabolic dependency in hematopoiesis and leukemogenesis
Wang, Ying-Hua, Israelsen, William J, Lee, Dongjun, Yu, Vionnie W C, Jeanson, Nathaniel T, Clish, Clary B, Cantley, Lewis C, Vander Heiden, Matthew G, Scadden, David T
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SIRT3 Reverses Aging-Associated Degeneration
Brown, Katharine, Xie, Stephanie, Qiu, Xiaolei, Mohrin, Mary, Shin, Jiyung, Liu, Yufei, Zhang, Dan, Scadden, David T., Chen, Danica
Published in Cell reports (Cambridge) (21.02.2013)
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Endogenous Bone Marrow MSCs Are Dynamic, Fate-Restricted Participants in Bone Maintenance and Regeneration
Park, Dongsu, Spencer, Joel A., Koh, Bong Ihn, Kobayashi, Tatsuya, Fujisaki, Joji, Clemens, Thomas L., Lin, Charles P., Kronenberg, Henry M., Scadden, David T.
Published in Cell stem cell (02.03.2012)
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Cancers predispose neutrophils to release extracellular DNA traps that contribute to cancer-associated thrombosis
Demers, Mélanie, Krause, Daniela S, Schatzberg, Daphne, Martinod, Kimberly, Voorhees, Jaymie R, Fuchs, Tobias A, Scadden, David T, Wagner, Denisa D
Published in Proceedings of the National Academy of Sciences - PNAS (07.08.2012)
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Bone progenitor dysfunction induces myelodysplasia and secondary leukaemia
Raaijmakers, Marc H. G. P, Scadden, David. T, Mukherjee, Siddhartha, Guo, Shangqin, Zhang, Siyi, Kobayashi, Tatsuya, Schoonmaker, Jesse A, Ebert, Benjamin L, Al-Shahrour, Fatima, Hasserjian, Robert P, Scadden, Edward O, Aung, Zinmar, Matza, Marc, Merkenschlager, Matthias, Lin, Charles, Rommens, Johanna M
Published in Nature (London) (08.04.2010)
Published in Nature (London) (08.04.2010)
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Direct measurement of local oxygen concentration in the bone marrow of live animals
Spencer, Joel A., Ferraro, Francesca, Roussakis, Emmanuel, Klein, Alyssa, Wu, Juwell, Runnels, Judith M., Zaher, Walid, Mortensen, Luke J., Alt, Clemens, Turcotte, Raphaël, Yusuf, Rushdia, Côté, Daniel, Vinogradov, Sergei A., Scadden, David T., Lin, Charles P.
Published in Nature (London) (10.04.2014)
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Distinct bone marrow blood vessels differentially regulate haematopoiesis
Itkin, Tomer, Gur-Cohen, Shiri, Spencer, Joel A., Schajnovitz, Amir, Ramasamy, Saravana K., Kusumbe, Anjali P., Ledergor, Guy, Jung, Yookyung, Milo, Idan, Poulos, Michael G., Kalinkovich, Alexander, Ludin, Aya, Golan, Karin, Khatib, Eman, Kumari, Anju, Kollet, Orit, Shakhar, Guy, Butler, Jason M., Rafii, Shahin, Adams, Ralf H., Scadden, David T., Lin, Charles P., Lapidot, Tsvee
Published in Nature (London) (21.04.2016)
Published in Nature (London) (21.04.2016)
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Leukaemogenic effects of Ptpn11 activating mutations in the stem cell microenvironment
Dong, Lei, Yu, Wen-Mei, Zheng, Hong, Loh, Mignon L., Bunting, Silvia T., Pauly, Melinda, Huang, Gang, Zhou, Muxiang, Broxmeyer, Hal E., Scadden, David T., Qu, Cheng-Kui
Published in Nature (London) (10.11.2016)
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dropEst: pipeline for accurate estimation of molecular counts in droplet-based single-cell RNA-seq experiments
Petukhov, Viktor, Guo, Jimin, Baryawno, Ninib, Severe, Nicolas, Scadden, David T, Samsonova, Maria G, Kharchenko, Peter V
Published in Genome Biology (19.06.2018)
Published in Genome Biology (19.06.2018)
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Programmable microencapsulation for enhanced mesenchymal stem cell persistence and immunomodulation
Mao, Angelo S., Özkale, Berna, Shah, Nisarg J., Vining, Kyle H., Descombes, Tiphaine, Zhang, Liyuan, Tringides, Christina M., Wong, Sing-Wan, Shin, Jae-Won, Scadden, David T., Weitz, David A., Mooney, David J.
Published in Proceedings of the National Academy of Sciences - PNAS (30.07.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (30.07.2019)
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Angiogenin Promotes Hematopoietic Regeneration by Dichotomously Regulating Quiescence of Stem and Progenitor Cells
Goncalves, Kevin A., Silberstein, Lev, Li, Shuping, Severe, Nicolas, Hu, Miaofen G., Yang, Hailing, Scadden, David T., Hu, Guo-fu
Published in Cell (11.08.2016)
Published in Cell (11.08.2016)
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Stress-Induced Changes in Bone Marrow Stromal Cell Populations Revealed through Single-Cell Protein Expression Mapping
Severe, Nicolas, Karabacak, Nezihi Murat, Gustafsson, Karin, Baryawno, Ninib, Courties, Gabriel, Kfoury, Youmna, Kokkaliaris, Konstantinos D., Rhee, Catherine, Lee, Dongjun, Scadden, Elizabeth W., Garcia-Robledo, Juan Esteban, Brouse, Thomas, Nahrendorf, Matthias, Toner, Mehmet, Scadden, David T.
Published in Cell stem cell (03.10.2019)
Published in Cell stem cell (03.10.2019)
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