Pharmacokinetics and Pharmacodynamics of Imatinib in a Phase I Trial With Chronic Myeloid Leukemia Patients
Peng, Bin, Hayes, Michael, Resta, Debra, Racine-Poon, Amy, Druker, Brian J, Talpaz, Moshe, Sawyers, Charles L, Rosamilia, Marianne, Ford, John, Lloyd, Peter, Capdeville, Renaud
Published in Journal of clinical oncology (01.03.2004)
Published in Journal of clinical oncology (01.03.2004)
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GREB1 amplifies androgen receptor output in human prostate cancer and contributes to antiandrogen resistance
Lee, Eugine, Wongvipat, John, Choi, Danielle, Wang, Ping, Lee, Young Sun, Zheng, Deyou, Watson, Philip A, Gopalan, Anuradha, Sawyers, Charles L
Published in eLife (15.01.2019)
Published in eLife (15.01.2019)
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Efficacy and Safety of a Specific Inhibitor of the BCR-ABL Tyrosine Kinase in Chronic Myeloid Leukemia
Druker, Brian J, Talpaz, Moshe, Resta, Debra J, Peng, Bin, Buchdunger, Elisabeth, Ford, John M, Lydon, Nicholas B, Kantarjian, Hagop, Capdeville, Renaud, Ohno-Jones, Sayuri, Sawyers, Charles L
Published in The New England journal of medicine (05.04.2001)
Published in The New England journal of medicine (05.04.2001)
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Mammalian target of rapamycin inhibition promotes response to epidermal growth factor receptor kinase inhibitors in PTEN-deficient and PTEN-intact glioblastoma cells
WANG, Maria Y, LU, Kan V, MISCHEL, Paul S, SHAOJUN ZHU, DIA, Ederlyn Q, VIVANCO, Igor, SHACKLEFORD, Gregory M, CAVENEE, Webster K, MELLINGHOFF, Ingo K, CLOUGHESY, Timothy F, SAWYERS, Charles L
Published in Cancer research (Chicago, Ill.) (15.08.2006)
Published in Cancer research (Chicago, Ill.) (15.08.2006)
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Identification of the JNK Signaling Pathway as a Functional Target of the Tumor Suppressor PTEN
Vivanco, Igor, Palaskas, Nicolaos, Tran, Chris, Finn, Stephen P., Getz, Gad, Kennedy, Norman J., Jiao, Jing, Rose, Joshua, Xie, Wanling, Loda, Massimo, Golub, Todd, Mellinghoff, Ingo K., Davis, Roger J., Wu, Hong, Sawyers, Charles L.
Published in Cancer cell (01.06.2007)
Published in Cancer cell (01.06.2007)
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Persistence of malignant hematopoietic progenitors in chronic myelogenous leukemia patients in complete cytogenetic remission following imatinib mesylate treatment
Bhatia, Ravi, Holtz, Melissa, Niu, Ning, Gray, Rachel, Snyder, David S., Sawyers, Charles L., Arber, Daniel A., Slovak, Marilyn L., Forman, Stephen J.
Published in Blood (15.06.2003)
Published in Blood (15.06.2003)
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All the World's a Stage: Facilitating Discovery Science and Improved Cancer Care through the Global Alliance for Genomics and Health
Lawler, Mark, Siu, Lillian L, Rehm, Heidi L, Chanock, Stephen J, Alterovitz, Gil, Burn, John, Calvo, Fabien, Lacombe, Denis, Teh, Bin Tean, North, Kathryn N, Sawyers, Charles L
Published in Cancer discovery (01.11.2015)
Published in Cancer discovery (01.11.2015)
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AKT Activity Determines Sensitivity to Mammalian Target of Rapamycin (mTOR) Inhibitors by Regulating Cyclin D1 and c-myc Expression
Gera, Joseph F., Mellinghoff, Ingo K., Shi, Yijiang, Rettig, Matthew B., Tran, Chris, Hsu, Jung-hsin, Sawyers, Charles L., Lichtenstein, Alan K.
Published in The Journal of biological chemistry (23.01.2004)
Published in The Journal of biological chemistry (23.01.2004)
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MYC cooperates with AKT in prostate tumorigenesis and alters sensitivity to mTOR inhibitors
Clegg, Nicola J, Couto, Suzana S, Wongvipat, John, Hieronymus, Haley, Carver, Brett S, Taylor, Barry S, Ellwood-Yen, Katharine, Gerald, William L, Sander, Chris, Sawyers, Charles L
Published in PloS one (04.03.2011)
Published in PloS one (04.03.2011)
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Detection of BCR-ABL kinase mutations in CD34+ cells from chronic myelogenous leukemia patients in complete cytogenetic remission on imatinib mesylate treatment
Chu, Su, Xu, Helen, Shah, Neil P., Snyder, David S., Forman, Stephen J., Sawyers, Charles L., Bhatia, Ravi
Published in Blood (01.03.2005)
Published in Blood (01.03.2005)
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Modulators of prostate cancer cell proliferation and viability identified by short-hairpin RNA library screening
Dahlman, Kimberly Brown, Parker, Joel S, Shamu, Tambudzai, Hieronymus, Haley, Chapinski, Caren, Carver, Brett, Chang, Kenneth, Hannon, Gregory J, Sawyers, Charles L
Published in PloS one (11.04.2012)
Published in PloS one (11.04.2012)
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Organoid culture systems for prostate epithelial and cancer tissue
Drost, Jarno, Karthaus, Wouter R, Gao, Dong, Driehuis, Else, Sawyers, Charles L, Chen, Yu, Clevers, Hans
Published in Nature protocols (01.02.2016)
Published in Nature protocols (01.02.2016)
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Phosphorylation of the ATP-binding loop directs oncogenicity of drug-resistant BCR-ABL mutants
Skaggs, Brian J, Gorre, Mercedes E, Ryvkin, Ann, Burgess, Michael R, Xie, Yongming, Han, Yun, Komisopoulou, Evangelia, Brown, Lauren M, Loo, Joseph A, Landaw, Elliot M, Sawyers, Charles L, Graeber, Thomas G
Published in Proceedings of the National Academy of Sciences - PNAS (19.12.2006)
Published in Proceedings of the National Academy of Sciences - PNAS (19.12.2006)
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Developing Standards for Breakthrough Therapy Designation in Oncology
HORNING, Sandra J, HABER, Daniel A, SELIG, Wendy K. D, IVY, S. Percy, ROBERTS, Samantha A, ALLEN, Jeff D, SIGAL, Ellen V, SAWYERS, Charles L
Published in Clinical cancer research (15.08.2013)
Published in Clinical cancer research (15.08.2013)
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Assessment of TROP2, CEACAM5 and DLL3 in metastatic prostate cancer: Expression landscape and molecular correlates
Ajkunic, Azra, Sayar, Erolcan, Roudier, Martine P., Patel, Radhika A., Coleman, Ilsa M., De Sarkar, Navonil, Hanratty, Brian, Adil, Mohamed, Zhao, Jimmy, Zaidi, Samir, True, Lawrence D., Sperger, Jamie M., Cheng, Heather H., Yu, Evan Y., Montgomery, Robert B., Hawley, Jessica E., Ha, Gavin, Persse, Thomas, Galipeau, Patricia, Lee, John K., Harmon, Stephanie A., Corey, Eva, Lang, Joshua M., Sawyers, Charles L., Morrissey, Colm, Schweizer, Michael T., Gulati, Roman, Nelson, Peter S., Haffner, Michael C.
Published in NPJ precision oncology (17.05.2024)
Published in NPJ precision oncology (17.05.2024)
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