Development of torsadogenic risk assessment using human induced pluripotent stem cell-derived cardiomyocytes: Japan iPS Cardiac Safety Assessment (JiCSA) update
Kanda, Yasunari, Yamazaki, Daiju, Osada, Tomoharu, Yoshinaga, Takashi, Sawada, Kohei
Published in Journal of pharmacological sciences (01.12.2018)
Published in Journal of pharmacological sciences (01.12.2018)
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International Multisite Study of Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes for Drug Proarrhythmic Potential Assessment
Blinova, Ksenia, Dang, Qianyu, Millard, Daniel, Smith, Godfrey, Pierson, Jennifer, Guo, Liang, Brock, Mathew, Lu, Hua Rong, Kraushaar, Udo, Zeng, Haoyu, Shi, Hong, Zhang, Xiaoyu, Sawada, Kohei, Osada, Tomoharu, Kanda, Yasunari, Sekino, Yuko, Pang, Li, Feaster, Tromondae K., Kettenhofen, Ralf, Stockbridge, Norman, Strauss, David G., Gintant, Gary
Published in Cell reports (Cambridge) (25.09.2018)
Published in Cell reports (Cambridge) (25.09.2018)
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A New Perspective in the Field of Cardiac Safety Testing through the Comprehensive In Vitro Proarrhythmia Assay Paradigm
Fermini, Bernard, Hancox, Jules C, Abi-Gerges, Najah, Bridgland-Taylor, Matthew, Chaudhary, Khuram W, Colatsky, Thomas, Correll, Krystle, Crumb, William, Damiano, Bruce, Erdemli, Gul, Gintant, Gary, Imredy, John, Koerner, John, Kramer, James, Levesque, Paul, Li, Zhihua, Lindqvist, Anders, Obejero-Paz, Carlos A, Rampe, David, Sawada, Kohei, Strauss, David G, Vandenberg, Jamie I
Published in Journal of biomolecular screening (01.01.2016)
Published in Journal of biomolecular screening (01.01.2016)
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Journal Article
Assessment of Testing Methods for Drug-Induced Repolarization Delay and Arrhythmias in an iPS Cell–Derived Cardiomyocyte Sheet: Multi-site Validation Study
Nakamura, Yuji, Matsuo, Junko, Miyamoto, Norimasa, Ojima, Atsuko, Ando, Kentaro, Kanda, Yasunari, Sawada, Kohei, Sugiyama, Atsushi, Sekino, Yuko
Published in Journal of Pharmacological Sciences (2014)
Published in Journal of Pharmacological Sciences (2014)
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Electrophysiological Characteristics of Human iPSC-Derived Cardiomyocytes for the Assessment of Drug-Induced Proarrhythmic Potential
Yamamoto, Wataru, Asakura, Keiichi, Ando, Hiroyuki, Taniguchi, Tomohiko, Ojima, Atsuko, Uda, Takaaki, Osada, Tomoharu, Hayashi, Seiji, Kasai, Chieko, Miyamoto, Norimasa, Tashibu, Hiroyuki, Yoshinaga, Takashi, Yamazaki, Daiju, Sugiyama, Atsushi, Kanda, Yasunari, Sawada, Kohei, Sekino, Yuko
Published in PloS one (06.12.2016)
Published in PloS one (06.12.2016)
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Importance of beating rate control for the analysis of drug effects on contractility in human induced pluripotent stem cell-derived cardiomyocytes
Hinata, Yuto, Kagawa, Yuki, Kubo, Hirotsugu, Kato, Eriko, Baba, Atsushi, Sasaki, Daisuke, Matsuura, Katsuhisa, Sawada, Kohei, Shimizu, Tatsuya
Published in Journal of pharmacological and toxicological methods (01.11.2022)
Published in Journal of pharmacological and toxicological methods (01.11.2022)
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Journal Article
Arrhythmic hazard map for a 3D whole‐ventricle model under multiple ion channel block
Okada, Jun‐ichi, Yoshinaga, Takashi, Kurokawa, Junko, Washio, Takumi, Furukawa, Tetsushi, Sawada, Kohei, Sugiura, Seiryo, Hisada, Toshiaki
Published in British journal of pharmacology (01.09.2018)
Published in British journal of pharmacology (01.09.2018)
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Journal Article
Hsp90 inhibitor geldanamycin attenuates the cytotoxicity of sunitinib in cardiomyocytes via inhibition of the autophagy pathway
Kimura, Takayuki, Uesugi, Mai, Takase, Kazuma, Miyamoto, Norimasa, Sawada, Kohei
Published in Toxicology and applied pharmacology (15.08.2017)
Published in Toxicology and applied pharmacology (15.08.2017)
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Journal Article
Low-density plating is sufficient to induce cardiac hypertrophy and electrical remodeling in highly purified human iPS cell-derived cardiomyocytes
Uesugi, Mai, Ojima, Atsuko, Taniguchi, Tomohiko, Miyamoto, Norimasa, Sawada, Kohei
Published in Journal of pharmacological and toxicological methods (01.03.2014)
Published in Journal of pharmacological and toxicological methods (01.03.2014)
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Growth of structure-controlled polycrystalline silicon ingots for solar cells by casting
Fujiwara, Kozo, Pan, Wugen, Usami, Noritaka, Sawada, Kohei, Tokairin, Masatoshi, Nose, Yoshitaro, Nomura, Akiko, Shishido, Toetsu, Nakajima, Kazuo
Published in Acta materialia (01.07.2006)
Published in Acta materialia (01.07.2006)
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Chloroquine and hydroxychloroquine provoke arrhythmias at concentrations higher than those clinically used to treat COVID‐19: A simulation study
Okada, Jun‐ichi, Yoshinaga, Takashi, Washio, Takumi, Sawada, Kohei, Sugiura, Seiryo, Hisada, Toshiaki
Published in Clinical and Translational Science (01.05.2021)
Published in Clinical and Translational Science (01.05.2021)
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Screening system for drug-induced arrhythmogenic risk combining a patch clamp and heart simulator
Okada, Jun-Ichi, Yoshinaga, Takashi, Kurokawa, Junko, Washio, Takumi, Furukawa, Tetsushi, Sawada, Kohei, Sugiura, Seiryo, Hisada, Toshiaki
Published in Science advances (01.05.2015)
Published in Science advances (01.05.2015)
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Emotion estimation using a wearable heart rate monitoring device in Asian elephants (Elephas maximus) during veterinary clinical procedures
KIDO, Nobuhide, TANAKA, Sohei, OMIYA, Tomoko, KAMITE, Yuko, SAWADA, Kohei, KOMATSU, Yoko, SHOJI, Yasuyuki, SENZAKI, Masaru, HANZAWA, Sayuri, ANDO, Masato, SUTO, Ikko
Published in Journal of Veterinary Medical Science (2020)
Published in Journal of Veterinary Medical Science (2020)
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A novel method of selecting human embryonic stem cell-derived cardiomyocyte clusters for assessment of potential to influence QT interval
Yamazaki, Kazuto, Hihara, Taro, Taniguchi, Tomohiko, Kohmura, Naohiro, Yoshinaga, Takashi, Ito, Masashi, Sawada, Kohei
Published in Toxicology in vitro (01.03.2012)
Published in Toxicology in vitro (01.03.2012)
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Design, synthesis, and characterization of BK channel openers based on oximation of abietane diterpene derivatives
Cui, Yong-Mei, Yasutomi, Eriko, Otani, Yuko, Ido, Katsutoshi, Yoshinaga, Takashi, Sawada, Kohei, Ohwada, Tomohiko
Published in Bioorganic & medicinal chemistry (15.12.2010)
Published in Bioorganic & medicinal chemistry (15.12.2010)
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Journal Article
A patient presenting painful chest wall swelling: Tietze syndrome
Sawada, Kohei, Ihoriya, Hiromi, Yamada, Taihei, Yumoto, Tetsuya, Tsukahara, Kohei, Osako, Takaaki, Naito, Hiromichi, Nakao, Atsunori
Published in World journal of emergency medicine (01.04.2019)
Published in World journal of emergency medicine (01.04.2019)
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