Pharmacokinetics of Organic Cation Transporter 1 (OCT1) Substrates in Oct1/2 Knockout Mice and Species Difference in Hepatic OCT1-Mediated Uptake
Morse, Bridget L, Kolur, Anil, Hudson, Loyd R, Hogan, Andrew T, Chen, Lisa Hong, Brackman, Ryan M, Sawada, Geri A, Fallon, John K, Smith, Philip C, Hillgren, Kathleen M
Published in Drug metabolism and disposition (01.02.2020)
Published in Drug metabolism and disposition (01.02.2020)
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Journal Article
In Silico and in Vitro Assessment of OATP1B1 Inhibition in Drug Discovery
Danielson, Matthew L, Sawada, Geri A, Raub, Thomas J, Desai, Prashant V
Published in Molecular pharmaceutics (06.08.2018)
Published in Molecular pharmaceutics (06.08.2018)
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Journal Article
Advances in blood-brain barrier modeling in microphysiological systems highlight critical differences in opioid transport due to cortisol exposure
Brown, Jacquelyn A, Faley, Shannon L, Shi, Yajuan, Hillgren, Kathleen M, Sawada, Geri A, Baker, Thomas K, Wikswo, John P, Lippmann, Ethan S
Published in Fluids and barriers of the CNS (03.06.2020)
Published in Fluids and barriers of the CNS (03.06.2020)
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Journal Article
QSAR Model of Unbound Brain-to-Plasma Partition Coefficient, Kp,uu,brain: Incorporating P-glycoprotein Efflux as a Variable
Dolgikh, Elena, Watson, Ian A, Desai, Prashant V, Sawada, Geri A, Morton, Stuart, Jones, Timothy M, Raub, Thomas J
Published in Journal of chemical information and modeling (28.11.2016)
Published in Journal of chemical information and modeling (28.11.2016)
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Journal Article
Breast Cancer Resistance Protein Interacts with Various Compounds in Vitro, but Plays a Minor Role in Substrate Efflux at the Blood-Brain Barrier
RONG ZHAO, RAUB, Thomas J, SAWADA, Geri A, KASPER, Steven C, BACON, James A, BRIDGES, Arlene S, POLLACK, Gary M
Published in Drug metabolism and disposition (01.06.2009)
Published in Drug metabolism and disposition (01.06.2009)
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Journal Article
Rhodamine Inhibitors of P-Glycoprotein: An Amide/Thioamide “Switch” for ATPase Activity
Gannon, Michael K, Holt, Jason J, Bennett, Stephanie M, Wetzel, Bryan R, Loo, Tip W, Bartlett, M. Claire, Clarke, David M, Sawada, Geri A, Higgins, J. William, Tombline, Gregory, Raub, Thomas J, Detty, Michael R
Published in Journal of medicinal chemistry (28.05.2009)
Published in Journal of medicinal chemistry (28.05.2009)
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Journal Article
Brain Exposure of Two Selective Dual CDK4 and CDK6 Inhibitors and the Antitumor Activity of CDK4 and CDK6 Inhibition in Combination with Temozolomide in an Intracranial Glioblastoma Xenograft
Raub, Thomas J, Wishart, Graham N, Kulanthaivel, Palaniappan, Staton, Brian A, Ajamie, Rose T, Sawada, Geri A, Gelbert, Lawrence M, Shannon, Harlan E, Sanchez-Martinez, Concepcion, De Dios, Alfonso
Published in Drug metabolism and disposition (01.09.2015)
Published in Drug metabolism and disposition (01.09.2015)
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Journal Article
Chalcogenopyrylium Compounds as Modulators of the ATP-Binding Cassette Transporters P-Glycoprotein (P-gp/ABCB1) and Multidrug Resistance Protein 1 (MRP1/ABCC1)
Ebert, Sean P, Wetzel, Bryan, Myette, Robert L, Conseil, Gwenaëlle, Cole, Susan P. C, Sawada, Geri A, Loo, Tip W, Bartlett, M. Claire, Clarke, David M, Detty, Michael R
Published in Journal of medicinal chemistry (24.05.2012)
Published in Journal of medicinal chemistry (24.05.2012)
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Journal Article
Selective photodepletion of malignant T cells in extracorporeal photopheresis with selenorhodamine photosensitizers
McIver, Zachariah A., Kryman, Mark W., Choi, Young, Coe, Benjamin N., Schamerhorn, Gregory A., Linder, Michelle K., Davies, Kellie S., Hill, Jacqueline E., Sawada, Geri A., Grayson, Jason M., Detty, Michael R.
Published in Bioorganic & medicinal chemistry (01.09.2016)
Published in Bioorganic & medicinal chemistry (01.09.2016)
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Journal Article
QSAR Model of Unbound Brain-to-Plasma Partition Coefficient, K p,uu,brain: Incorporating P‑glycoprotein Efflux as a Variable
Dolgikh, Elena, Watson, Ian A, Desai, Prashant V, Sawada, Geri A, Morton, Stuart, Jones, Timothy M, Raub, Thomas J
Published in Journal of chemical information and modeling (28.11.2016)
Published in Journal of chemical information and modeling (28.11.2016)
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Journal Article
Enterohepatic circulation of glucuronide metabolites of drugs in dog
Zhou, Xin, Cassidy, Kenneth C., Hudson, Loyd, Mohutsky, Michael A., Sawada, Geri A., Hao, Junliang
Published in Pharmacology research & perspectives (01.08.2019)
Published in Pharmacology research & perspectives (01.08.2019)
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Journal Article
Thiorhodamines containing amide and thioamide functionality as inhibitors of the ATP-binding cassette drug transporter P-glycoprotein (ABCB1)
Orchard, Alexandra, Schamerhorn, Gregory A., Calitree, Brandon D., Sawada, Geri A., Loo, Tip W., Claire Bartlett, M., Clarke, David M., Detty, Michael R.
Published in Bioorganic & medicinal chemistry (15.07.2012)
Published in Bioorganic & medicinal chemistry (15.07.2012)
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Journal Article
ATP Occlusion by P-Glycoprotein as a Surrogate Measure for Drug Coupling
Tombline, Gregory, Holt, Jason J, Gannon, Michael K, Donnelly, David J, Wetzel, Bryan, Sawada, Geri A, Raub, Thomas J, Detty, Michael R
Published in Biochemistry (Easton) (11.03.2008)
Published in Biochemistry (Easton) (11.03.2008)
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Journal Article
Chalcogenopyrylium dyes as inhibitors/modulators of P-glycoprotein in multidrug-resistant cells
Sawada, Geri A., Raub, Thomas J., William Higgins, J., Brennan, Nancy K., Moore, Teiah M., Tombline, Gregory, Detty, Michael R.
Published in Bioorganic & medicinal chemistry (15.11.2008)
Published in Bioorganic & medicinal chemistry (15.11.2008)
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Journal Article
Increased Lipophilicity and Subsequent Cell Partitioning Decrease Passive Transcellular Diffusion of Novel, Highly Lipophilic Antioxidants
Sawada, G A, Barsuhn, C L, Lutzke, B S, Houghton, M E, Padbury, G E, Ho, N F, Raub, T J
Published in The Journal of pharmacology and experimental therapeutics (01.03.1999)
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Published in The Journal of pharmacology and experimental therapeutics (01.03.1999)
Journal Article
Expression of a P-Selectin Ligand in Zona Pellucida of Porcine Oocytes and P-Selectin on Acrosomal Membrane of Porcine Sperm Cells. Potential Implications for Their Involvement in Sperm-Egg Interactions
Geng, Jian-Guo, Raub, Thomas J., Baker, Carolyn A., Sawada, Geri A., Ma, Li, Elhammer, Åke P.
Published in The Journal of cell biology (05.05.1997)
Published in The Journal of cell biology (05.05.1997)
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Journal Article
QSAR Model of Unbound Brain-to-Plasma Partition Coefficient, K^sub p,uu,brain^: Incorporating P-glycoprotein Efflux as a Variable
Dolgikh, Elena, Watson, Ian A, Desai, Prashant V, Sawada, Geri A, Morton, Stuart, Jones, Timothy M, Raub, Thomas J
Published in Journal of chemical information and modeling (28.11.2016)
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Published in Journal of chemical information and modeling (28.11.2016)
Journal Article