Evaluation of 5‑(Trifluoromethyl)-1,2,4-oxadiazole-Based Class IIa HDAC Inhibitors for Huntington’s Disease
Stott, Andrew J, Maillard, Michel C, Beaumont, Vahri, Allcock, David, Aziz, Omar, Borchers, Alexander H, Blackaby, Wesley, Breccia, Perla, Creighton-Gutteridge, Gillian, Haughan, Alan F, Jarvis, Rebecca E, Luckhurst, Christopher A, Matthews, Kim L, McAllister, George, Pollack, Scott, Saville-Stones, Elizabeth, Van de Poël, Amanda J, Vater, Huw D, Vann, Julie, Williams, Rachel, Yates, Dawn, Muñoz-Sanjuán, Ignacio, Dominguez, Celia
Published in ACS medicinal chemistry letters (11.03.2021)
Published in ACS medicinal chemistry letters (11.03.2021)
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Potent, Selective, and CNS-Penetrant Tetrasubstituted Cyclopropane Class IIa Histone Deacetylase (HDAC) Inhibitors
Luckhurst, Christopher A, Breccia, Perla, Stott, Andrew J, Aziz, Omar, Birch, Helen L, Bürli, Roland W, Hughes, Samantha J, Jarvis, Rebecca E, Lamers, Marieke, Leonard, Philip M, Matthews, Kim L, McAllister, George, Pollack, Scott, Saville-Stones, Elizabeth, Wishart, Grant, Yates, Dawn, Dominguez, Celia
Published in ACS medicinal chemistry letters (14.01.2016)
Published in ACS medicinal chemistry letters (14.01.2016)
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히스톤 탈아세틸효소 억제제 및 그것의 조성물 및 사용 방법
WISHART GRANT, DOMINGUEZ CELIA, MAILLARD MICHEL C, JARVIS REBECCA E, BRECCIA PERLA, SAVILLE STONES ELIZABETH A, VAN DE POEL AMANDA, HAUGHAN ALAN F, LUCKHURST CHRISTOPHER A, WALL MICHAEL, STOTT ANDREW J
Year of Publication 08.01.2018
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Year of Publication 08.01.2018
Patent
히스톤 탈아세틸효소 억제제 및 그것의 조성물 및 사용 방법
WISHART GRANT, DOMINGUEZ CELIA, MAILLARD MICHEL C, JARVIS REBECCA E, VAN DE POEL AMANDA, SAVILLE STONES ELIZABETH A, BRECCIA PERLA, HAUGHAN ALAN F, LUCKHURST CHRISTOPHER A, WALL MICHAEL, STOTT ANDREW J
Year of Publication 08.01.2018
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Year of Publication 08.01.2018
Patent
Identification of a Potent, Selective, and Brain-Penetrant Rho Kinase Inhibitor and its Activity in a Mouse Model of Huntington’s Disease
Ladduwahetty, Tammy, Lee, Matthew R., Maillard, Michel C., Cachope, Roger, Todd, Daniel, Barnes, Michael, Beaumont, Vahri, Chauhan, Alka, Gallati, Caroline, Haughan, Alan F., Kempf, Georg, Luckhurst, Christopher A., Matthews, Kim, McAllister, George, Mitchell, Philip, Patel, Hiral, Rose, Mark, Saville-Stones, Elizabeth, Steinbacher, Stefan, Stott, Andrew J., Thatcher, Emma, Tierney, Jason, Urbonas, Liudvikas, Munoz-Sanjuan, Ignacio, Dominguez, Celia
Published in Journal of medicinal chemistry (28.07.2022)
Published in Journal of medicinal chemistry (28.07.2022)
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HISTONE DEACETYLASE INHIBITORS AND COMPOSITIONS AND METHODS OF USE THEREOF
WISHART GRANT, PENROSE STEPHEN D, SAVILLE STONES ELIZABETH, JARVIS REBECCA E, RAPHY GILLES, MUNOZ SANJUAN IGNACIO, LUCKHURST CHRISTOPHER A, HAUGHAN ALAN F, ALLEN DANIEL R, BURLI ROLAND W, DOMINGUEZ CELIA, BRECCIA PERLA, WALL MICHAEL, HUGHES SAMANTHA J, VATER HUW D, STOTT ANDREW J
Year of Publication 02.02.2017
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Year of Publication 02.02.2017
Patent
Evaluation of 5-(Trifluoromethyl)-1,2,4-oxadiazole-Based Class Ila HDAC Inhibitors for Huntington's Disease
Stott, Andrew J., Maillard, Michel C., Beaumont, Vahri, Allcock, David, Aziz, Omar, Borchers, Alexander H., Blackaby, Wesley, Breccia, Perla, Creighton-Gutteridge, Gillian, Haughan, Alan F., Jarvis, Rebecca E., Luckhurst, Christopher A., Matthews, Kim L., McAllister, George, Pollack, Scott, Saville-Stones, Elizabeth, Van de Poel, Amanda J., Vater, Huw D., Vann, Julie, Williams, Rachel, Yates, Dawn, Munoz-Sanjuan, Ignacio, Dominguez, Celia
Published in ACS medicinal chemistry letters (11.03.2021)
Published in ACS medicinal chemistry letters (11.03.2021)
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Journal Article
Potent, Selective, and CNS-Penetrant Tetrasubstituted Cyclopropane Class Ila Histone Deacetylase (HDAC) Inhibitors
Luckhurst, Christopher A., Breccia, Perla, Stott, Andrew J., Aziz, Omar, Birch, Helen L., Buerli, Roland W., Hughes, Samantha J., Jarvis, Rebecca E., Lamers, Marieke, Leonard, Philip M., Matthews, Kim L., McAllister, George, Pollack, Scott, Saville-Stones, Elizabeth, Wishart, Grant, Yates, Dawn, Dominguez, Celia
Published in ACS medicinal chemistry letters (01.01.2016)
Published in ACS medicinal chemistry letters (01.01.2016)
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Synthesis of inhibitors of imidazole glycerol phosphate dehydratase
Lindell, Stephen D., Earnshaw, Christopher G., Wright (deceased), Brian J., Carver, David S., O'Mahony, Mary J., Saville-Stones, Elizabeth A.
Published in Bioorganic & medicinal chemistry letters (05.03.1996)
Published in Bioorganic & medicinal chemistry letters (05.03.1996)
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Polyfunctionalisation of imidazole via sequential imidazolyl anion formation
Carver, David S., Lindell, Stephen D., Saville-Stones, Elizabeth A.
Published in Tetrahedron (20.10.1997)
Published in Tetrahedron (20.10.1997)
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HISTONE DEACETYLASE INHIBITORS AND COMPOSITIONS AND METHODS OF USE THEREOF
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Year of Publication 09.01.2024
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Year of Publication 09.01.2024
Patent
HISTONE DEACETYLASE INHIBITORS AND COMPOSITIONS AND METHODS OF USE THEREOF
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Year of Publication 26.09.2023
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Year of Publication 26.09.2023
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HISTONE DEACETYLASE INHIBITORS AND COMPOSITIONS AND METHODS OF USE THEREOF
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Year of Publication 10.08.2022
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Year of Publication 10.08.2022
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Histone deacetylase inhibitors and compositions and methods of use thereof
Stott, Andrew J, Jarvis, Rebecca E, Haughan, Alan F, Wall, Michael, Maillard, Michel C, Van De Poël, Amanda, Luckhurst, Christopher A, Breccia, Perla, Saville-Stones, Elizabeth A, Wishart, Grant, Dominguez, Celia
Year of Publication 26.08.2021
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Year of Publication 26.08.2021
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Histone deacetylase inhibitors and compositions and methods of use thereof
Jarvis, Rebecca E, Stott, Andrew J, Haughan, Alan F, Wall, Michael, Maillard, Michel C, Van De Poël, Amanda, Luckhurst, Christopher A, Breccia, Perla, Saville-Stones, Elizabeth A, Wishart, Grant, Dominguez, Celia
Year of Publication 26.08.2021
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Year of Publication 26.08.2021
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HISTONE DEACETYLASE INHIBITORS AND COMPOSITIONS AND METHODS OF USE THEREOF
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Year of Publication 25.08.2021
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Year of Publication 25.08.2021
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HISTONE DEACETYLASE INHIBITORS AND COMPOSITIONS AND METHODS OF USE THEREOF
DOMINGUEZ, Celia, HUGHES, Samantha J, SAVILLE-STONES, Elizabeth, LUCKHURST, Christopher A, STOTT, Andrew J, BRECCIA, Perla, WISHART, Grant, MUN OZ-SANJUAN, Ignacio, BÛRLI, Roland W, HAUGHAN, Alan F, JARVIS, Rebecca E, ALLEN, Daniel R, VATER, Huw D, PENROSE, Stephen D, RAPHY, Gilles, WALL, Michael
Year of Publication 17.02.2021
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Year of Publication 17.02.2021
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HISTONE DEACETYLASE INHIBITORS AND COMPOSITIONS AND METHODS OF USE THEREOF
Stott, Andrew J, Jarvis, Rebecca E, Haughan, Alan F, Wall, Michael, Maillard, Michel C, Luckhurst, Christopher A, Breccia, Perla, Van de Poël, Amanda, Saville-Stones, Elizabeth A, Wishart, Grant, Dominguez, Celia
Year of Publication 04.07.2019
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Year of Publication 04.07.2019
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