Search Results - "SAVARAJ, Niramol" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Phase 2 study of pembrolizumab and circulating biomarkers to predict anticancer response in advanced, unresectable hepatocellular carcinoma

Phase 2 study of pembrolizumab and circulating biomarkers to predict anticancer response in advanced, unresectable hepatocellular carcinoma

by Feun, Lynn G., Li, Ying‐Ying, Wu, Chunjing, Wangpaichitr, Medhi, Jones, Patricia D., Richman, Stephen P., Madrazo, Beatrice, Kwon, Deukwoo, Garcia‐Buitrago, Monica, Martin, Paul, Hosein, Peter J., Savaraj, Niramol
Published in Cancer (15.10.2019)

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Targeting of the Hedgehog signal transduction pathway suppresses survival of malignant pleural mesothelioma cells in vitro

Targeting of the Hedgehog signal transduction pathway suppresses survival of malignant pleural mesothelioma cells in vitro

by You, Min, PhD, Varona-Santos, Javier, PhD, Singh, Samer, PhD, Robbins, David J., PhD, Savaraj, Niramol, MD, Nguyen, Dao M., MD, MSc, FRCSC, FACS
Published in The Journal of thoracic and cardiovascular surgery (2014)

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Activation of Ras/PI3K/ERK Pathway Induces c-Myc Stabilization to Upregulate Argininosuccinate Synthetase, Leading to Arginine Deiminase Resistance in Melanoma Cells

Activation of Ras/PI3K/ERK Pathway Induces c-Myc Stabilization to Upregulate Argininosuccinate Synthetase, Leading to Arginine Deiminase Resistance in Melanoma Cells

by TSAI, Wen-Bin, AIBA, Isamu, YAN LONG, LIN, Hui-Kuan, FEUN, Lynn, SAVARAJ, Niramol, TIEN KUO, Macus
Published in Cancer research (Chicago, Ill.) (15.05.2012)

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2-Deoxy-d-glucose activates autophagy via endoplasmic reticulum stress rather than ATP depletion

2-Deoxy-d-glucose activates autophagy via endoplasmic reticulum stress rather than ATP depletion

by Xi, Haibin, Kurtoglu, Metin, Liu, Huaping, Wangpaichitr, Medhi, You, Min, Liu, Xiongfei, Savaraj, Niramol, Lampidis, Theodore J.
Published in Cancer chemotherapy and pharmacology (01.04.2011)

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Role of the Human High-Affinity Copper Transporter in Copper Homeostasis Regulation and Cisplatin Sensitivity in Cancer Chemotherapy

Role of the Human High-Affinity Copper Transporter in Copper Homeostasis Regulation and Cisplatin Sensitivity in Cancer Chemotherapy

by TIEN KUO, Macus, SIQING FU, SAVARAJ, Niramol, CHEN, Helen H. W
Published in Cancer research (Chicago, Ill.) (15.09.2012)

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Cisplatin Resistance and Redox-Metabolic Vulnerability: A Second Alteration

Cisplatin Resistance and Redox-Metabolic Vulnerability: A Second Alteration

by Wangpaichitr, Medhi, Theodoropoulos, George, Nguyen, Dan J M, Wu, Chunjing, Spector, Sydney A, Feun, Lynn G, Savaraj, Niramol
Published in International journal of molecular sciences (09.07.2021)

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The roles of copper transporters in cisplatin resistance

The roles of copper transporters in cisplatin resistance

by Kuo, Macus Tien, Chen, Helen H W, Song, Im-Sook, Savaraj, Niramol, Ishikawa, Toshihisa
Published in Cancer and metastasis reviews (01.03.2007)

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Targeting the Proline-Glutamine-Asparagine-Arginine Metabolic Axis in Amino Acid Starvation Cancer Therapy

Targeting the Proline-Glutamine-Asparagine-Arginine Metabolic Axis in Amino Acid Starvation Cancer Therapy

by Kuo, Macus Tien, Chen, Helen H W, Feun, Lynn G, Savaraj, Niramol
Published in Pharmaceuticals (Basel, Switzerland) (18.01.2021)

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Resistance to arginine deiminase treatment in melanoma cells is associated with induced argininosuccinate synthetase expression involving c-Myc/HIF-1α/Sp4

Resistance to arginine deiminase treatment in melanoma cells is associated with induced argininosuccinate synthetase expression involving c-Myc/HIF-1α/Sp4

by Tsai, Wen-Bin, Aiba, Isamu, Lee, Soo-yong, Feun, Lynn, Savaraj, Niramol, Kuo, Macus Tien
Published in Molecular cancer therapeutics (01.12.2009)

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Under normoxia, 2-deoxy-d-glucose elicits cell death in select tumor types not by inhibition of glycolysis but by interfering with N-linked glycosylation

Under normoxia, 2-deoxy-d-glucose elicits cell death in select tumor types not by inhibition of glycolysis but by interfering with N-linked glycosylation

by Kurtoglu, Metin, Gao, Ningguo, Shang, Jie, Maher, Johnathan C, Lehrman, Mark A, Wangpaichitr, Medhi, Savaraj, Niramol, Lane, Andrew N, Lampidis, Theodore J
Published in Molecular cancer therapeutics (01.11.2007)

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Enhancing the Effect of Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand Signaling and Arginine Deprivation in Melanoma

Enhancing the Effect of Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand Signaling and Arginine Deprivation in Melanoma

by Wu, Chunjing, You, Min, Nguyen, Dao, Wangpaichitr, Medhi, Li, Ying-Ying, Feun, Lynn G., Kuo, Macus T., Savaraj, Niramol
Published in International journal of molecular sciences (16.07.2021)

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The relationship of thioredoxin-1 and cisplatin resistance: its impact on ROS and oxidative metabolism in lung cancer cells

The relationship of thioredoxin-1 and cisplatin resistance: its impact on ROS and oxidative metabolism in lung cancer cells

by Wangpaichitr, Medhi, Sullivan, Elizabeth J, Theodoropoulos, George, Wu, Chunjing, You, Min, Feun, Lynn G, Lampidis, Theodore J, Kuo, Macus T, Savaraj, Niramol
Published in Molecular cancer therapeutics (01.03.2012)

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Mechanistic basis for overcoming platinum resistance using copper chelating agents

Mechanistic basis for overcoming platinum resistance using copper chelating agents

by Liang, Zheng D, Long, Yan, Tsai, Wen-Bin, Fu, Siqing, Kurzrock, Razelle, Gagea-Iurascu, Mihai, Zhang, Fan, Chen, Helen H W, Hennessy, Bryan T, Mills, Gordon B, Savaraj, Niramol, Kuo, Macus Tien
Published in Molecular cancer therapeutics (01.11.2012)

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Journal Article

Autophagic Mechanism in Anti-Cancer Immunity: Its Pros and Cons for Cancer Therapy

Autophagic Mechanism in Anti-Cancer Immunity: Its Pros and Cons for Cancer Therapy

by Li, Ying-Ying, Feun, Lynn G, Thongkum, Angkana, Tu, Chiao-Hui, Chen, Shu-Mei, Wangpaichitr, Medhi, Wu, Chunjing, Kuo, Macus T, Savaraj, Niramol
Published in International journal of molecular sciences (19.06.2017)

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The Combination of Arginine Deprivation and 5-Fluorouracil Improves Therapeutic Efficacy in Argininosuccinate Synthetase Negative Hepatocellular Carcinoma

The Combination of Arginine Deprivation and 5-Fluorouracil Improves Therapeutic Efficacy in Argininosuccinate Synthetase Negative Hepatocellular Carcinoma

by Thongkum, Angkana, Wu, Chunjing, Li, Ying-Ying, Wangpaichitr, Medhi, Navasumrit, Panida, Parnlob, Varabhorn, Sricharunrat, Thaniya, Bhudhisawasdi, Vajarabhongsa, Ruchirawat, Mathuros, Savaraj, Niramol
Published in International journal of molecular sciences (01.06.2017)

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2-deoxy-d-glucose increases the efficacy of adriamycin and paclitaxel in human osteosarcoma and non-small cell lung cancers in vivo

2-deoxy-d-glucose increases the efficacy of adriamycin and paclitaxel in human osteosarcoma and non-small cell lung cancers in vivo

by MASCHEK, Gregory, SAVARAJ, Niramol, PRIEBE, Waldemar, BRAUNSCHWEIGER, Paul, HAMILTON, Kara, TIDMARSH, George F, DE YOUNG, Linda R, LAMPIDIS, Theodore J
Published in Cancer research (Chicago, Ill.) (2004)

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Collaboration Between RSK-EphA2 and Gas6-Axl RTK Signaling in Arginine Starvation Response That Confers Resistance to EGFR Inhibitors

Collaboration Between RSK-EphA2 and Gas6-Axl RTK Signaling in Arginine Starvation Response That Confers Resistance to EGFR Inhibitors

by Kuo, Macus Tien, Long, Yan, Tsai, Wen-Bin, Li, Ying-Ying, Chen, Helen H.W., Feun, Lynn G., Savaraj, Niramol
Published in Translational oncology (01.02.2020)

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Dual inhibition of IDO1/TDO2 enhances anti-tumor immunity in platinum-resistant non-small cell lung cancer

Dual inhibition of IDO1/TDO2 enhances anti-tumor immunity in platinum-resistant non-small cell lung cancer

by Wu, Chunjing, Spector, Sydney A, Theodoropoulos, George, Nguyen, Dan J M, Kim, Emily Y, Garcia, Ashley, Savaraj, Niramol, Lim, Diane C, Paul, Ankita, Feun, Lynn G, Bickerdike, Michael, Wangpaichitr, Medhi
Published in Cancer & metabolism (24.05.2023)

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Mechanistic Comparison of Human High-Affinity Copper Transporter 1-Mediated Transport between Copper Ion and Cisplatin

Mechanistic Comparison of Human High-Affinity Copper Transporter 1-Mediated Transport between Copper Ion and Cisplatin

by Liang, Zheng D, Stockton, David, Savaraj, Niramol, Tien Kuo, Macus
Published in Molecular pharmacology (01.10.2009)

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Journal Article

Degradation of AMPK‐α1 sensitizes BRAF inhibitor‐resistant melanoma cells to arginine deprivation

Degradation of AMPK‐α1 sensitizes BRAF inhibitor‐resistant melanoma cells to arginine deprivation

by Li, Ying‐Ying, Wu, Chunjing, Shah, Sumedh S., Chen, Shu‐Mei, Wangpaichitr, Medhi, Kuo, Macus T., Feun, Lynn G., Han, Xiaoqing, Suarez, Miguel, Prince, Jeffrey, Savaraj, Niramol
Published in Molecular oncology (01.12.2017)

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