Preparation of Saxagliptin, a Novel DPP-IV Inhibitor
Savage, Scott A, Jones, Gregory S, Kolotuchin, Sergei, Ramrattan, Shelly Ann, Vu, Truc, Waltermire, Robert E
Published in Organic process research & development (20.11.2009)
Published in Organic process research & development (20.11.2009)
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Journal Article
Efficient Synthesis of 4-, 5-, and 6-Methyl-2,2‘-bipyridine by a Negishi Cross-Coupling Strategy Followed by High-Yield Conversion to Bromo- and Chloromethyl-2,2‘-bipyridines
Savage, Scott A, Smith, Adam P, Fraser, Cassandra L
Published in Journal of organic chemistry (25.12.1998)
Published in Journal of organic chemistry (25.12.1998)
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Journal Article
Utilizing Native Directing Groups: Synthesis of a Selective IKur Inhibitor, BMS-919373, via a Regioselective C–H Arylation
Wisniewski, Steven R, Stevens, Jason M, Yu, Miao, Fraunhoffer, Kenneth J, Romero, Evan O, Savage, Scott A
Published in Journal of organic chemistry (19.04.2019)
Published in Journal of organic chemistry (19.04.2019)
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Journal Article
Development of Two Synthetic Approaches to an APJ Receptor Agonist Containing a Tetra-ortho-Substituted Biaryl Pyridone
Goldfogel, Matthew J, Jamison, Christopher R, Savage, Scott A, Haley, Matthew W, Mukherjee, Subha, Sfouggatakis, Chris, Gujjar, Manjunath, Mohan, Jayaraj, Rakshit, Souvik, Vaidyanathan, Rajappa
Published in Organic process research & development (18.03.2022)
Published in Organic process research & development (18.03.2022)
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Journal Article
Revisiting a Classic Transformation: A Lossen Rearrangement Initiated by Nitriles and “Pseudo-Catalytic” in Isocyanate
Strotman, Neil A, Ortiz, Adrian, Savage, Scott A, Wilbert, Christopher R, Ayers, Sloan, Kiau, Susanne
Published in Journal of organic chemistry (21.04.2017)
Published in Journal of organic chemistry (21.04.2017)
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Journal Article
Synthesis of HIV-Maturation Inhibitor BMS-955176 from Betulin by an Enabling Oxidation Strategy
Ortiz, Adrian, Soumeillant, Maxime, Savage, Scott A, Strotman, Neil A, Haley, Matthew, Benkovics, Tamas, Nye, Jeffrey, Xu, Zhongmin, Tan, Yichen, Ayers, Sloan, Gao, Qi, Kiau, Susanne
Published in Journal of organic chemistry (05.05.2017)
Published in Journal of organic chemistry (05.05.2017)
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Journal Article
Utilizing Native Directing Groups: Synthesis of a Selective I Kur Inhibitor, BMS-919373, via a Regioselective C-H Arylation
Wisniewski, Steven R, Stevens, Jason M, Yu, Miao, Fraunhoffer, Kenneth J, Romero, Evan O, Savage, Scott A
Published in Journal of organic chemistry (19.04.2019)
Published in Journal of organic chemistry (19.04.2019)
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Journal Article
Utilizing Native Directing Groups: Mechanistic Understanding of a Direct Arylation Leads to Formation of Tetracyclic Heterocycles via Tandem Intermolecular, Intramolecular C–H Activation
Wisniewski, Steven R, Savage, Scott A, Romero, Evan O, Eastgate, Martin D, Tan, Yichen, Simmons, Eric M, Plata, R. Erik, Sowa, John R, Blackmond, Donna G
Published in Journal of organic chemistry (21.06.2019)
Published in Journal of organic chemistry (21.06.2019)
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Journal Article
Kinetic and Mechanistic Insight into the Thermodynamic Degradation of Saxagliptin
Jones, G. Scott, Savage, Scott A, Ivy, Sabrina, Benitez, Patrick L, Ramirez, Antonio
Published in Journal of organic chemistry (16.12.2011)
Published in Journal of organic chemistry (16.12.2011)
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Journal Article
Using In Silico Tools To Map the Structural Landscape of Nitroxyl (HNO Donor) Compounds
Sandhu, Bhupinder, Savage, Scott A., Park, Hyunsoo, Ilott, Andrew, Albrecht, Jacob, Yin, Shawn, Sarjeant, Amy A.
Published in Crystal growth & design (06.07.2022)
Published in Crystal growth & design (06.07.2022)
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Journal Article
N-((1R,2S,5R)-5-(tert-부틸아미노)-2-((S)-3-(7-tert-부틸피라졸로[1,5-a][1,3,5]트리아진-4-일아미노)-2-옥소피롤리딘-1-일)시클로헥실)아세트아미드의 제조 방법
HICKEY MATTHEW R, RAZLER THOMAS M, LUO HELEN Y, LAUSER KATHLEEN, EASTGATE MARTIN D, AYTAR BURCU SELIN, GONZALEZ BOBES FRANCISCO, BOROVIKA ALINA, LEE HONG GEUN, DEERBERG JOERG, SFOUGGATAKIS CHRIS, LEAHY DAVID K, SOUMEILLANT MAXIME C.D, FAN YU, ZHU YE, KOPP NATHANIEL DAVID, CHAN COLLIN, SAVAGE SCOTT A, DOMAGALSKI NATHAN R, FENSTER MICHAEL DAVID BENGT, GREEN REBECCA A, FOREST ROBERT V, ZHENG BIN, ZARETSKY SERGE, LA CRUZ THOMAS E
Year of Publication 24.03.2020
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Year of Publication 24.03.2020
Patent
HIV 성숙화 억제제를 생산하는 방법
STROTMAN NEIL A, SOUMEILLANT MAXIME, HALEY MATTHEW W, HO JEANNE, EASTGATE MARTIN D, KIAU SUSANNE, XU ZHONGMIN, NYE JEFFREY A, ORTIZ ADRIAN, SAVAGE SCOTT A, BENKOVICS TAMAS, TAN YICHEN
Year of Publication 08.12.2017
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Year of Publication 08.12.2017
Patent
Process for the preparation of N-((1R,2S,5R)-5-(tert,-butylamino)-2- ((S)-3-(7-tert-butylpyrazolo[l,5-a][1,3,5]triazin-4-ylamino)-2- oxopyrrolidin- 1 -yl)c yclohexyl) acetamide
SFOUGGATAKIS, Chris, ZARETSKY, Serge, DOMAGALSKI, Nathan R, EASTGATE, Martin D, RAZLER, Thomas M, LA CRUZ, Thomas E, LAUSER, Kathleen, FENSTER, Michael David Bengt, SOUMEILLANT, Maxime C.D, AYTAR, Burcu Selin, LUO, Helen Y, FAN, Yu, LEE, Hong Geun, LEAHY, David K, KOPP, Nathaniel David, CHAN, Collin, ZHENG, Bin, SAVAGE, Scott A, FOREST, Robert V, GREEN, Rebecca A, HICKEY, Matthew R, DEERBERG, Joerg, GONZALEZ-BOBES, Francisco, BOROVIKA, Alina, ZHU, Ye
Year of Publication 17.11.2022
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Year of Publication 17.11.2022
Patent
Process for the preparation of n-((1r,2s,5r)-5-(tert-butylamino)-2-((s)-3-(7-tert-butylpyrazolo[1,5-a][1,3,5]triazin-4-ylamino)-2-oxopyrrolidin-1-yl)cyclohexyl)acetamide
DOMAGALSKI Nathan R, FOREST Robert V, BOROVIKA Alina, FAN Yu, AYTAR Burcu Selin, LAUSER Kathleen, GREEN Rebecca A, FENSTER Michael David Bengt, LEAHY David K, SAVAGE Scott A, ZHU Ye, LA CRUZ Thomas E, LEE Hong Geun, RAZLER Thomas M, HICKEY Matthew R, ZHENG Bin, ZARETSKY Serge, DEERBERG Joerg, CHAN Collin, EASTGATE Martin D, LUO Helen Y, SOUMEILLANT Maxime C.D, GONZALEZ-BOBES Francisco, SFOUGGATAKIS Chris, KOPP Nathaniel David
Year of Publication 01.07.2022
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Year of Publication 01.07.2022
Patent
PROCESS FOR THE PREPARATION OF N-((1R,2S,SR)-5-(TERT-BUTYLAMINO)-2-((S)-3-(7-TERT-BUTYLPYRAZOLO[1,5-A][1,3,5]TRIAZIN-4-YLAMINO)-2-OXOPYRROLIDIN-1-YL)CYCLOHEXYL)ACETAMIDE
SFOUGGATAKIS, Chris, ZARETSKY, Serge, DOMAGALSKI, Nathan R, EASTGATE, Martin D, RAZLER, Thomas M, LA CRUZ, Thomas E, LAUSER, Kathleen, FENSTER, Michael David Bengt, SOUMEILLANT, Maxime C.D, AYTAR, Burcu Selin, LUO, Helen Y, FAN, Yu, LEE, Hong Geun, LEAHY, David K, KOPP, Nathaniel David, CHAN, Collin, ZHENG, Bin, SAVAGE, Scott A, FOREST, Robert V, GREEN, Rebecca A, HICKEY, Matthew R, DEERBERG, Joerg, GONZALEZ-BOBES, Francisco, BOROVIKA, Alina, ZHU, Ye
Year of Publication 28.06.2022
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Year of Publication 28.06.2022
Patent
PROCESS FOR THE PREPARATION OF N-((1R,2S,5R)-5-(TERT-BUTYLAMINO)-2-((S)-3-(7-TERT-BUTYLPYRAZOLO[1,5-A][1,3,5]TRIAZIN-4-YLAMINO)-2-OXOPYRROLIDIN-1-YL)CYCLOHEXYL)ACETAMIDE
Fan, Yu, Eastgate, Martin D, Gonzalez-Bobes, Francisco, Hickey, Matthew R, Razler, Thomas M, Soumeillant, Maxime C.D, Aytar, Burcu Selin, Green, Rebecca A, Savage, Scott A, Sfouggatakis, Chris, Leahy, David K, Deerberg, Joerg, La Cruz, Thomas E, Borovika, Alina, Zaretsky, Serge, Zheng, Bin, Fenster, Michael David Bengt, Lauser, Kathleen, Zhu, Ye, Luo, Helen Y, Domagalski, Nathan R, Chan, Collin, Lee, Hong Geun, Kopp, Nathaniel David, Forest, Robert V
Year of Publication 09.06.2022
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Year of Publication 09.06.2022
Patent
Process for the preparation of n-((1r,2s,5r)-5-(tert-butylamino)-2-((s)-3-(7-tert-butylpyrazolo[1,5-a][1,3,5]triazin-4-ylamino)-2-oxopyrrolidin-1-yl)cyclohexyl)acetamide
DOMAGALSKI Nathan R, FOREST Robert V, FAN Yu, BOROVIKA Alina, AYTAR Burcu Selin, LAUSER Kathleen, GREEN Rebecca A, FENSTER Michael David Bengt, LEAHY David K, SAVAGE Scott A, ZHU Ye, LA CRUZ Thomas E, LEE Hong Geun, RAZLER Thomas M, HICKEY Matthew R, ZHENG Bin, ZARETSKY Serge, DEERBERG Joerg, CHAN Collin, EASTGATE Martin D, LUO Helen Y, SOUMEILLANT Maxime C.D, GONZALEZ-BOBES Francisco, SFOUGGATAKIS Chris, KOPP Nathaniel David
Year of Publication 01.06.2022
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Year of Publication 01.06.2022
Patent