Molecular Pathways: Targeting Protein Tyrosine Phosphatases in Cancer
Bollu, Lakshmi Reddy, Mazumdar, Abhijit, Savage, Michelle I, Brown, Powel H
Published in Clinical cancer research (01.05.2017)
Published in Clinical cancer research (01.05.2017)
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Comprehensive genomic analysis identifies novel subtypes and targets of triple-negative breast cancer
Burstein, Matthew D, Tsimelzon, Anna, Poage, Graham M, Covington, Kyle R, Contreras, Alejandro, Fuqua, Suzanne A W, Savage, Michelle I, Osborne, C Kent, Hilsenbeck, Susan G, Chang, Jenny C, Mills, Gordon B, Lau, Ching C, Brown, Powel H
Published in Clinical cancer research (01.04.2015)
Published in Clinical cancer research (01.04.2015)
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Molecularly targeted therapies for p53-mutant cancers
Zhao, Dekuang, Tahaney, William M., Mazumdar, Abhijit, Savage, Michelle I., Brown, Powel H.
Published in Cellular and molecular life sciences : CMLS (01.11.2017)
Published in Cellular and molecular life sciences : CMLS (01.11.2017)
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Identification of a BRCA1-mRNA Splicing Complex Required for Efficient DNA Repair and Maintenance of Genomic Stability
Savage, Kienan I., Gorski, Julia J., Barros, Eliana M., Irwin, Gareth W., Manti, Lorenzo, Powell, Alexander J., Pellagatti, Andrea, Lukashchuk, Natalia, McCance, Dennis J., McCluggage, W. Glenn, Schettino, Giuseppe, Salto-Tellez, Manuel, Boultwood, Jacqueline, Richard, Derek J., McDade, Simon S., Harkin, D. Paul
Published in Molecular cell (08.05.2014)
Published in Molecular cell (08.05.2014)
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The RNA processing factors THRAP3 and BCLAF1 promote the DNA damage response through selective mRNA splicing and nuclear export
Vohhodina, Jekaterina, Barros, Eliana M, Savage, Abigail L, Liberante, Fabio G, Manti, Lorenzo, Bankhead, Peter, Cosgrove, Nicola, Madden, Angelina F, Harkin, D Paul, Savage, Kienan I
Published in Nucleic acids research (15.12.2017)
Published in Nucleic acids research (15.12.2017)
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Targeted therapy for breast cancer prevention
den Hollander, Petra, Savage, Michelle I, Brown, Powel H
Published in Frontiers in oncology (23.09.2013)
Published in Frontiers in oncology (23.09.2013)
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The Nuclear Oncogene SET Controls DNA Repair by KAP1 and HP1 Retention to Chromatin
Kalousi, Alkmini, Hoffbeck, Anne-Sophie, Selemenakis, Platonas N., Pinder, Jordan, Savage, Kienan I., Khanna, Kum Kum, Brino, Laurent, Dellaire, Graham, Gorgoulis, Vassilis G., Soutoglou, Evi
Published in Cell reports (Cambridge) (07.04.2015)
Published in Cell reports (Cambridge) (07.04.2015)
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Disruption of SF3B1 results in deregulated expression and splicing of key genes and pathways in myelodysplastic syndrome hematopoietic stem and progenitor cells
Dolatshad, H, Pellagatti, A, Fernandez-Mercado, M, Yip, B H, Malcovati, L, Attwood, M, Przychodzen, B, Sahgal, N, Kanapin, A A, Lockstone, H, Scifo, L, Vandenberghe, P, Papaemmanuil, E, Smith, C W J, Campbell, P J, Ogawa, S, Maciejewski, J P, Cazzola, M, Savage, K I, Boultwood, J
Published in Leukemia (01.05.2015)
Published in Leukemia (01.05.2015)
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Cryptic splicing events in the iron transporter ABCB7 and other key target genes in SF3B1-mutant myelodysplastic syndromes
Dolatshad, H, Pellagatti, A, Liberante, F G, Llorian, M, Repapi, E, Steeples, V, Roy, S, Scifo, L, Armstrong, R N, Shaw, J, Yip, B H, Killick, S, Kušec, R, Taylor, S, Mills, K I, Savage, K I, Smith, C W J, Boultwood, J
Published in Leukemia (01.12.2016)
Published in Leukemia (01.12.2016)
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Journal Article
The novel phosphatase NUDT5 is a critical regulator of triple-negative breast cancer growth
Qian, Jing, Ma, Yanxia, Tahaney, William M, Moyer, Cassandra L, Lanier, Amanda, Hill, Jamal, Coleman, Darian, Koupaei, Negar, Hilsenbeck, Susan G, Savage, Michelle I, Page, Brent D G, Mazumdar, Abhijit, Brown, Powel H
Published in Breast cancer research : BCR (05.02.2024)
Published in Breast cancer research : BCR (05.02.2024)
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Journal Article
Correction: The novel phosphatase NUDT5 is a critical regulator of triple-negative breast cancer growth
Qian, Jing, Ma, Yanxia, Tahaney, William M, Moyer, Cassandra L, Lanier, Amanda, Hill, Jamal, Coleman, Darian, Koupaei, Negar, Hilsenbeck, Susan G, Savage, Michelle I, Page, Brent D G, Mazumdar, Abhijit, Brown, Powel H
Published in Breast cancer research : BCR (26.03.2024)
Published in Breast cancer research : BCR (26.03.2024)
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BRCA1 Deficiency Exacerbates Estrogen-Induced DNA Damage and Genomic Instability
SAVAGE, Kienan I, MATCHETT, Kyle B, POWELL, Alexander, MANTI, Lorenzo, MCDADE, Simon S, BEN HO PARK, PRISE, Kevin M, MCINTOSH, Stuart A, SALTO-TELLEZ, Manuel, RICHARD, Derek J, ELLIOTT, Christopher T, HARKIN, D. Paul, BARROS, Eliana M, COOPER, Kevin M, IRWIN, Gareth W, GORSKI, Julia J, ORR, Katy S, VOHHODINA, Jekaterina, KAVANAGH, Joy N, MADDEN, Angelina F
Published in Cancer research (Chicago, Ill.) (15.05.2014)
Published in Cancer research (Chicago, Ill.) (15.05.2014)
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Chronic loss of STAG2 leads to altered chromatin structure contributing to de-regulated transcription in AML
Smith, James S, Lappin, Katrina M, Craig, Stephanie G, Liberante, Fabio G, Crean, Clare M, McDade, Simon S, Thompson, Alexander, Mills, Ken I, Savage, Kienan I
Published in Journal of translational medicine (03.09.2020)
Published in Journal of translational medicine (03.09.2020)
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BRD7, a Subunit of SWI/SNF Complexes, Binds Directly to BRCA1 and Regulates BRCA1-Dependent Transcription
HARTE, Mary T, O'BRIEN, Garrett J, RYAN, Niamh M, GORSKI, Julia J, SAVAGE, Kienan I, CRAWFORD, Nyree T, MULLAN, Paul B, HARKIN, D. Paul
Published in Cancer research (Chicago, Ill.) (15.03.2010)
Published in Cancer research (Chicago, Ill.) (15.03.2010)
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NF-κB is a critical mediator of BRCA1-induced chemoresistance
Harte, M T, Gorski, J J, Savage, K I, Purcell, J W, Barros, E M, Burn, P M, McFarlane, C, Mullan, P B, Kennedy, R D, Perkins, N D, Harkin, D P
Published in Oncogene (06.02.2014)
Published in Oncogene (06.02.2014)
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Multifocal breast cancers are more prevalent in BRCA2 versus BRCA1 mutation carriers
McCrorie, Alan D, Ashfield, Susannah, Begley, Aislinn, Mcilmunn, Colin, Morrison, Patrick J, Boyd, Clinton, Eccles, Bryony, Greville‐Heygate, Stephanie, Copson, Ellen R, Cutress, Ramsey I, Eccles, Diana M, Savage, Kienan I, McIntosh, Stuart A
Published in The journal of pathology. Clinical research (01.04.2020)
Published in The journal of pathology. Clinical research (01.04.2020)
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COMMD4 functions with the histone H2A-H2B dimer for the timely repair of DNA double-strand breaks
Suraweera, Amila, Gandhi, Neha S., Beard, Sam, Burgess, Joshua T., Croft, Laura V., Bolderson, Emma, Naqi, Ali, Ashton, Nicholas W., Adams, Mark N., Savage, Kienan I., Zhang, Shu-Dong, O’Byrne, Kenneth J., Richard, Derek J.
Published in Communications biology (19.04.2021)
Published in Communications biology (19.04.2021)
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